scholarly article | Q13442814 |
P50 | author | William C. Sessa | Q64680365 |
David Fulton | Q88410298 | ||
P2093 | author name string | Yasuko Iwakiri | |
Jason Fontana | |||
Lisette Acevedo | |||
Roger Babbitt | |||
Stefan Zoellner | |||
Timothy J McCabe | |||
P2860 | cites work | Regulation of endothelium-derived nitric oxide production by the protein kinase Akt | Q22010149 |
Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation | Q22010150 | ||
Roles for insulin receptor, PI3-kinase, and Akt in insulin-signaling pathways related to production of nitric oxide in human vascular endothelial cells | Q22253424 | ||
NOSIP, a novel modulator of endothelial nitric oxide synthase activity | Q24290718 | ||
NOSTRIN: a protein modulating nitric oxide release and subcellular distribution of endothelial nitric oxide synthase | Q24321312 | ||
The first 35 amino acids and fatty acylation sites determine the molecular targeting of endothelial nitric oxide synthase into the Golgi region of cells: a green fluorescent protein study | Q24680049 | ||
Pulmonary phosphatidic acid phosphatase and lipid phosphate phosphohydrolase | Q28216832 | ||
Endothelial nitric oxide synthase is regulated by tyrosine phosphorylation and interacts with caveolin-1 | Q28296135 | ||
Targeting of nitric oxide synthase to endothelial cell caveolae via palmitoylation: implications for nitric oxide signaling | Q28609890 | ||
Interaction of oestrogen receptor with the regulatory subunit of phosphatidylinositol-3-OH kinase | Q30439814 | ||
Mutation of N-myristoylation site converts endothelial cell nitric oxide synthase from a membrane to a cytosolic protein | Q30464616 | ||
Mutagenesis of palmitoylation sites in endothelial nitric oxide synthase identifies a novel motif for dual acylation and subcellular targeting | Q33722544 | ||
A novel Golgi-localisation domain shared by a class of coiled-coil peripheral membrane proteins | Q33859187 | ||
Phosphorylation of Thr(495) regulates Ca(2+)/calmodulin-dependent endothelial nitric oxide synthase activity. | Q33950554 | ||
Nitric oxide mediates angiogenesis in vivo and endothelial cell growth and migration in vitro promoted by substance P. | Q34158412 | ||
Ras pathway signaling on endomembranes | Q35089365 | ||
Functional Expression of Endothelial Nitric Oxide Synthase Fused to Green Fluorescent Protein in Transgenic Mice | Q35792234 | ||
Nitric oxide synthase is localized predominantly in the Golgi apparatus and cytoplasmic vesicles of vascular endothelial cells | Q36680797 | ||
Nitric oxide synthase lies downstream from vascular endothelial growth factor-induced but not basic fibroblast growth factor-induced angiogenesis | Q37368066 | ||
Nitric oxide production contributes to the angiogenic properties of vascular endothelial growth factor in human endothelial cells | Q37376612 | ||
Calmodulin-dependent endothelium-derived relaxing factor/nitric oxide synthase activity is present in the particulate and cytosolic fractions of bovine aortic endothelial cells | Q37416665 | ||
Purification and characterization of particulate endothelium-derived relaxing factor synthase from cultured and native bovine aortic endothelial cells | Q37628594 | ||
Nitric oxide regulates exocytosis by S-nitrosylation of N-ethylmaleimide-sensitive factor. | Q39821682 | ||
Endothelial NO synthase phosphorylated at SER635 produces NO without requiring intracellular calcium increase | Q40622130 | ||
Receptor-Regulated Dynamic Interaction between Endothelial Nitric Oxide Synthase and Calmodulin Revealed by Fluorescence Resonance Energy Transfer in Living Cells | Q40628809 | ||
Phosphorylation of threonine 497 in endothelial nitric-oxide synthase coordinates the coupling of L-arginine metabolism to efficient nitric oxide production | Q40638231 | ||
Acute modulation of endothelial Akt/PKB activity alters nitric oxide-dependent vasomotor activity in vivo | Q40730346 | ||
Basal and stimulated protein S-nitrosylation in multiple cell types and tissues | Q40756642 | ||
Endothelial nitric oxide synthase activity is linked to its presence at cell-cell contacts | Q40759918 | ||
Localization of endothelial nitric-oxide synthase phosphorylated on serine 1179 and nitric oxide in Golgi and plasma membrane defines the existence of two pools of active enzyme. | Q40765690 | ||
Vesicle budding on Golgi membranes: regulation by G proteins and myosin motors | Q40845647 | ||
Membrane estrogen receptor engagement activates endothelial nitric oxide synthase via the PI3-kinase-Akt pathway in human endothelial cells | Q40849536 | ||
Trafficking of endothelial nitric-oxide synthase in living cells. Quantitative evidence supporting the role of palmitoylation as a kinetic trapping mechanism limiting membrane diffusion. | Q40938612 | ||
Palmitoylation of endothelial nitric oxide synthase is necessary for optimal stimulated release of nitric oxide: implications for caveolae localization | Q41158636 | ||
Acylation targets emdothelial nitric-oxide synthase to plasmalemmal caveolae | Q41215934 | ||
Myristoylation of endothelial cell nitric oxide synthase is important for extracellular release of nitric oxide | Q41269678 | ||
Role of the enzyme calmodulin-binding domain in membrane association and phospholipid inhibition of endothelial nitric oxide synthase | Q41334662 | ||
A polybasic domain or palmitoylation is required in addition to the CAAX motif to localize p21ras to the plasma membrane | Q41718569 | ||
Compensatory phosphorylation and protein-protein interactions revealed by loss of function and gain of function mutants of multiple serine phosphorylation sites in endothelial nitric-oxide synthase | Q42437220 | ||
Hypochlorite-modified low density lipoprotein inhibits nitric oxide synthesis in endothelial cells via an intracellular dislocalization of endothelial nitric-oxide synthase | Q43559341 | ||
Sphingosine 1-phosphate and activation of endothelial nitric-oxide synthase. differential regulation of Akt and MAP kinase pathways by EDG and bradykinin receptors in vascular endothelial cells | Q43559410 | ||
Sphingosine 1-phosphate activates Akt, nitric oxide production, and chemotaxis through a Gi protein/phosphoinositide 3-kinase pathway in endothelial cells | Q43559665 | ||
Reciprocal phosphorylation and regulation of endothelial nitric-oxide synthase in response to bradykinin stimulation | Q43599368 | ||
The GRIP domain is a specific targeting sequence for a population of trans-Golgi network derived tubulo-vesicular carriers. | Q43605992 | ||
Endothelial nitric oxide synthase and its negative regulator caveolin-1 localize to distinct perinuclear organelles | Q43999127 | ||
Subcellular targeting and agonist-induced site-specific phosphorylation of endothelial nitric-oxide synthase | Q44110016 | ||
Synergistic activation of endothelial nitric-oxide synthase (eNOS) by HSP90 and Akt: calcium-independent eNOS activation involves formation of an HSP90-Akt-CaM-bound eNOS complex | Q44473651 | ||
Chaperone-dependent regulation of endothelial nitric-oxide synthase intracellular trafficking by the co-chaperone/ubiquitin ligase CHIP. | Q44595338 | ||
Production of PtdInsP3 at endomembranes is triggered by receptor endocytosis | Q44607820 | ||
A tool coming of age: thapsigargin as an inhibitor of sarco-endoplasmic reticulum Ca(2+)-ATPases | Q48014886 | ||
P433 | issue | 29 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | endothelium | Q111140 |
P304 | page(s) | 30349-30357 | |
P577 | publication date | 2004-05-10 | |
P1433 | published in | Journal of Biological Chemistry | Q867727 |
P1476 | title | Targeting of endothelial nitric-oxide synthase to the cytoplasmic face of the Golgi complex or plasma membrane regulates Akt- versus calcium-dependent mechanisms for nitric oxide release | |
P478 | volume | 279 |
Q90171736 | A DNA-based fluorescent probe maps NOS3 activity with subcellular spatial resolution |
Q46044599 | AMP-Activated Protein Kinase and Sirtuin 1 Coregulation of Cortactin Contributes to Endothelial Function |
Q53590999 | Aberrant cytoplasmic sequestration of eNOS in endothelial cells after monocrotaline, hypoxia, and senescence: live-cell caveolar and cytoplasmic NO imaging. |
Q35957168 | Activation of Endothelial Nitric Oxide (eNOS) Occurs through Different Membrane Domains in Endothelial Cells |
Q33900675 | Activation of hypoxia-inducible factors in hyperoxia through prolyl 4-hydroxylase blockade in cells and explants of primate lung |
Q49734562 | Altered angiogenesis in caveolin-1 gene-deficient mice is restored by ablation of endothelial nitric oxide synthase. |
Q37050456 | Antioxidant properties of glutamine and its role in VEGF-Akt pathways in portal hypertension gastropathy. |
Q24620561 | Argininosuccinate synthase: at the center of arginine metabolism |
Q28509077 | CYP1B1 and endothelial nitric oxide synthase combine to sustain proangiogenic functions of endothelial cells under hyperoxic stress |
Q28211479 | Cardioprotective effects of nitric oxide-aspirin in myocardial ischemia-reperfused rats |
Q47721484 | Caveolin 1 Promotes Renal Water and Salt Reabsorption. |
Q37421145 | Caveolin-1 mediates endotoxin inhibition of endothelin-1-induced endothelial nitric oxide synthase activity in liver sinusoidal endothelial cells |
Q38509844 | Compartmentalized nitric oxide signaling in the resistance vasculature |
Q39209626 | Contemporary Approaches to Modulating the Nitric Oxide-cGMP Pathway in Cardiovascular Disease |
Q41906283 | Coordinated endothelial nitric oxide synthase activation by translocation and phosphorylation determines flow-induced nitric oxide production in resistance vessels |
Q46781614 | Differences in eNOS activity because of subcellular localization are dictated by phosphorylation state rather than the local calcium environment. |
Q46792342 | Dissociation of endothelial nitric oxide synthase phosphorylation and activity in uterine artery endothelial cells |
Q57146623 | Effect of spatial heterogeneity and colocalization of eNOS and capacitative calcium entry channels on shear stress-induced NO production by endothelial cells: A modeling approach |
Q33901272 | Endogenous NO upon estradiol-17β stimulation and NO donor differentially regulate mitochondrial S-nitrosylation in endothelial cells |
Q36873738 | Endomembrane H-Ras controls vascular endothelial growth factor-induced nitric-oxide synthase-mediated endothelial cell migration |
Q49960687 | Endothelial Cell Autonomous Role of Akt1: Regulation of Vascular Tone and Ischemia-Induced Arteriogenesis. |
Q30278654 | Endothelial nitric oxide synthase in the microcirculation |
Q52568380 | Endothelial nitric oxide synthase is segregated from caveolin-1 and localizes to the leading edge of migrating cells. |
Q34033512 | Endothelial-specific overexpression of caveolin-1 accelerates atherosclerosis in apolipoprotein E-deficient mice |
Q35536905 | Ephrin type-B receptor 4 activation reduces neointimal hyperplasia in human saphenous vein in vitro. |
Q39998327 | Estrogen and the Ca2+-mobilizing agonist ATP evoke acute NO synthesis via distinct pathways in an individual human vascular endothelium-derived cell |
Q49789512 | Flow-mediated dilation stimulated by sustained increases in shear stress: A useful tool for assessing endothelial function in humans? |
Q35182857 | Functional significance of cytosolic endothelial nitric-oxide synthase (eNOS): regulation of hyperpermeability |
Q39478189 | G-PKDrep-live, a genetically encoded FRET reporter to measure PKD activity at the trans-Golgi-network |
Q38772779 | Gasotransmitter Heterocellular Signaling |
Q48337356 | Glucose, insulin, and leptin signaling pathways modulate nitric oxide synthesis in glucose-inhibited neurons in the ventromedial hypothalamus |
Q33565388 | HMG-CoA reductase inhibitor improves endothelial dysfunction in spontaneous hypertensive rats via down-regulation of caveolin-1 and activation of endothelial nitric oxide synthase |
Q28566787 | Hypothyroid phenotype is contributed by mitochondrial complex I inactivation due to translocated neuronal nitric-oxide synthase |
Q36118353 | Identification of Golgi-localized acyl transferases that palmitoylate and regulate endothelial nitric oxide synthase |
Q40276985 | Inhibition of MEK/ERK1/2 signalling alters endothelial nitric oxide synthase activity in an agonist-dependent manner |
Q34530182 | Inorganic nitrite and chronic tissue ischaemia: a novel therapeutic modality for peripheral vascular diseases. |
Q37142734 | Insights into the arginine paradox: evidence against the importance of subcellular location of arginase and eNOS. |
Q42815226 | Interaction of the endothelial nitric oxide synthase with the CAT-1 arginine transporter enhances NO release by a mechanism not involving arginine transport |
Q46510601 | Intracellular location regulates calcium-calmodulin-dependent activation of organelle-restricted eNOS. |
Q91881339 | Metabolomic changes of the multi (-AGC-) kinase inhibitor AT13148 in cells, mice and patients are associated with NOS regulation |
Q37887771 | Nitric oxide: a guardian for vascular grafts? |
Q37595822 | Nitrones reverse hyperglycemia-induced endothelial dysfunction in bovine aortic endothelial cells |
Q36964950 | Oleanolic acid induces relaxation and calcium-independent release of endothelium-derived nitric oxide. |
Q37408105 | Paradoxical activation of endothelial nitric oxide synthase by NADPH oxidase |
Q37821307 | Physiopathology of splanchnic vasodilation in portal hypertension |
Q34586633 | Platelet-endothelial cell adhesion molecule-1 regulates endothelial NO synthase activity and localization through signal transducers and activators of transcription 3-dependent NOSTRIN expression |
Q21129237 | Post-translational regulation of endothelial nitric oxide synthase in vascular endothelium |
Q28818673 | Potential implication of the chemical properties and bioactivity of nitrone spin traps for therapeutics |
Q88124089 | Reciprocal regulation of eNOS and caveolin-1 functions in endothelial cells |
Q36472633 | Recruitment of dynamic endothelial Ca2+ signals by the TRPA1 channel activator AITC in rat cerebral arteries |
Q41871145 | Role of local production of endothelium-derived nitric oxide on cGMP signaling and S-nitrosylation. |
Q37663691 | S-Nitrosation of β-catenin and p120 catenin: a novel regulatory mechanism in endothelial hyperpermeability. |
Q35492444 | S-nitrosylation in the regulation of gene transcription |
Q42232104 | S-nitrosylation of proteins: a new insight into endothelial cell function regulated by eNOS-derived NO. |
Q37204142 | Specificity in S-nitrosylation: a short-range mechanism for NO signaling? |
Q36488231 | Subcellular targeting and trafficking of nitric oxide synthases |
Q41112424 | The Molecular Basis of Portal Hypertension |
Q34007426 | The N-terminal portion of autoinhibitory element modulates human endothelial nitric-oxide synthase activity through coordinated controls of phosphorylation at Thr495 and Ser1177. |
Q30434679 | The trafficking/interaction of eNOS and caveolin-1 induced by insulin modulates endothelial nitric oxide production |
Q35071651 | Translocation of endothelial nitric-oxide synthase involves a ternary complex with caveolin-1 and NOSTRIN. |
Q46832332 | Transport-dependent calcium signaling in spatially segregated cellular caveolar domains |
Q43002344 | Where is endothelial nitric oxide synthase more critical: plasma membrane or Golgi? |
Q35889758 | eNOS activation and NO function: structural motifs responsible for the posttranslational control of endothelial nitric oxide synthase activity |
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