Pulmonary phosphatidic acid phosphatase and lipid phosphate phosphohydrolase

scientific article (publication date: 2003)

Pulmonary phosphatidic acid phosphatase and lipid phosphate phosphohydrolase is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1152/AJPCELL.00460.2002
10.1152/AJPLUNG.00029.2002
P3181OpenCitations bibliographic resource ID271048
P698PubMed publication ID12471011

P2093author name stringFred Possmayer
Meera Nanjundan
P2860cites workMolecular cloning and functional characterization of a novel mammalian sphingosine kinase type 2 isoformQ22253469
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Sequential actions of phospholipase D and phosphatidic acid phosphohydrolase 2b generate diglyceride in mammalian cellsQ24651630
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Folate receptors targeted to clathrin-coated pits cannot regulate vitamin uptakeQ34382612
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Mammalian Mg2+-independent phosphatidate phosphatase (PAP2) displays diacylglycerol pyrophosphate phosphatase activityQ34421337
Ten years of protein kinase B signalling: a hard Akt to followQ34432885
Signalling roles of mammalian phospholipase D1 and D2.Q34437828
Diacylglycerol--when is it an intracellular messenger?Q34482095
Lipid phosphate phosphatases regulate signal transduction through glycerolipids and sphingolipidsQ34691427
Segregation of heterotrimeric G proteins in cell surface microdomains. G(q) binds caveolin to concentrate in caveolae, whereas G(i) and G(s) target lipid rafts by defaultQ34990345
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Signal transducing molecules and glycosyl-phosphatidylinositol-linked proteins form a caveolin-rich insoluble complex in MDCK cellsQ36232566
Purification and characterization of smooth muscle cell caveolaeQ36234345
Dynamin at the neck of caveolae mediates their budding to form transport vesicles by GTP-driven fission from the plasma membrane of endotheliumQ36255255
Identification of a novel phosphatase sequence motifQ36280312
ON BIMOLECULAR LAYERS OF LIPOIDS ON THE CHROMOCYTES OF THE BLOODQ24684323
Identification and characterization of a gene encoding phospholipase D activity in yeastQ27930171
Isolation and characterization of the Saccharomyces cerevisiae DPP1 gene encoding diacylglycerol pyrophosphate phosphatase.Q27935613
Regulation of the Saccharomyces cerevisiae DPP1-encoded diacylglycerol pyrophosphate phosphatase by zincQ27937324
Isolation and characterization of a structural homologue of human PRK2 from rat liver. Distinguishing substrate and lipid activator specificitiesQ28119092
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Functional characterization of human sphingosine kinase-1Q28143917
Properties and functions of diacylglycerol kinasesQ28143959
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Back in the water: the return of the inositol phosphatesQ28186774
Molecular characterization of the type 2 phosphatidic acid phosphataseQ28198800
The fluid mosaic model of the structure of cell membranesQ28239890
Inositol trisphosphate and calcium signallingQ28262867
Inducible gene targeting in mice using the Cre/lox systemQ28272460
Diacylglycerols and phosphatidates: which molecular species are intracellular messengers?Q28274993
Association of SH2 domain protein tyrosine phosphatases with the epidermal growth factor receptor in human tumor cells. Phosphatidic acid activates receptor dephosphorylation by PTP1CQ28297366
Characterization of two alternately spliced forms of phospholipase D1. Activation of the purified enzymes by phosphatidylinositol 4,5-bisphosphate, ADP-ribosylation factor, and Rho family monomeric GTP-binding proteins and protein kinase C-alphaQ28302448
Co-option of endocytic functions of cellular caveolae by pathogensQ28347332
Structural organization of mammalian lipid phosphate phosphatases: implications for signal transductionQ28508570
Protein kinase N (PKN) and PKN-related protein rhophilin as targets of small GTPase RhoQ28511023
Characterization of a Rac1- and RhoGDI-associated lipid kinase signaling complexQ28567098
Differential expression of cyclin D2 and cdc2 genes in proliferating and nonproliferating alveolar epithelial cellsQ28571048
Cloning, expression, and characterization of a novel phospholipase D complementary DNA from rat brainQ28579191
Mice mutant for Ppap2c, a homolog of the germ cell migration regulator wunen, are viable and fertileQ28579971
Molecular cloning and expression of pulmonary lipid phosphate phosphohydrolasesQ28580156
Identification and cDNA cloning of 35-kDa phosphatidic acid phosphatase (type 2) bound to plasma membranes. Polymerase chain reaction amplification of mouse H2O2-inducible hic53 clone yielded the cDNA encoding phosphatidic acid phosphataseQ28593858
Mammalian lipid phosphate phosphohydrolasesQ28594743
Phosphatidate phosphatases and diacylglycerol pyrophosphate phosphatases in Saccharomyces cerevisiae and Escherichia coliQ28609584
Structure, function, and control of phosphoinositide-specific phospholipase CQ28646117
Sphingosine-1-Phosphate Signaling via the EDG-1 Family of G-Protein-Coupled ReceptorsQ29394420
The caveolae membrane systemQ29614726
Inositol phosphates and cell signallingQ29615042
Maintenance of the differentiated type II cell phenotype by culture with an apical air surfaceQ46558665
The Drosophila protein Wunen repels migrating germ cellsQ47071906
Cationic lipids, phosphatidylethanolamine and the intracellular delivery of polymeric, nucleic acid-based drugs (review).Q47614304
cDNA cloning of an alternative splicing variant of protein kinase C delta (PKC deltaIII), a new truncated form of PKCdelta, in ratsQ47878773
Cloning and characterization of phospholipase D from rat brainQ48042634
Secretory vesicle budding from the trans-Golgi network is mediated by phosphatidic acid levels.Q48432795
Transgenic models for study of lung morphogenesis and repair: Parker B. Francis lecture.Q48576568
Fas ligand expression coincides with alveolar cell apoptosis in late-gestation fetal lung development.Q52163651
The cyclin D1 gene is transcriptionally repressed by caveolin-1.Q52169522
Immunoisolation of caveolae with high affinity antibody binding to the oligomeric caveolin cage. Toward understanding the basis of purification.Q52535988
Mg2-dependent phosphatidate phosphohydrolase of rat lung: development of an assay employing a defined chemical substrate which reflects the phosphohydrolase activity measured using membrane-bound substrate.Q54388841
Agonist-modulated targeting of the EDG-1 receptor to plasmalemmal caveolae. eNOS activation by sphingosine 1-phosphate and the role of caveolin-1 in sphingolipid signal transduction.Q55034100
A contribution to the theory of permeability of thin filmsQ55967051
Phospholipase D1 Is Phosphorylated and Activated by Protein Kinase C in Caveolin-enriched Microdomains within the Plasma MembraneQ57371832
Phospholipase A2 and arachidonate increase in bronchoalveolar lavage fluid after inhaled antigen challenge in asthmaticsQ58857468
Stimulation of Biosynthesis of GlycerideQ59029978
A tale of two messengersQ59052080
Role of transcription factors in fetal lung development and surfactant protein gene expression.Q33938823
N-terminal protein acylation confers localization to cholesterol, sphingolipid-enriched membranes but not to lipid rafts/caveolaeQ33948557
Charting the fate of the "good cholesterol": identification and characterization of the high-density lipoprotein receptor SR-BI.Q33953583
Potential role of EDG receptors and lysophospholipids as their endogenous ligands in the respiratory tractQ33954330
Physiological and nutritional regulation of enzymes of triacylglycerol synthesisQ34001422
Apoptosis in lung pathophysiologyQ34012836
Protein kinase C isozymes and the regulation of diverse cell responsesQ34012841
Cell-free activation of neutrophil NADPH oxidase by a phosphatidic acid-regulated protein kinaseQ34018461
ABC transporters in cellular lipid traffickingQ34069104
Calcium-independent phospholipase A(2): structure and function.Q34083751
Cellular components that functionally interact with signaling phospholipase A(2)sQ34083797
Multidrug resistance: a role for cholesterol efflux pathways?Q34085592
Insolubility of lipids in triton X-100: physical origin and relationship to sphingolipid/cholesterol membrane domains (rafts).Q34088700
Cholesterol and caveolae: structural and functional relationshipsQ34101258
Lipid traffic: the ABC of transbilayer movementQ34156610
Stimulation by phospholipids of a protein-tyrosine-phosphatase containing two src homology 2 domainsQ36288543
Antigen-induced generation of lyso-phospholipids in human airways.Q36366671
Hormonal regulation of caveolae internalizationQ36382786
Isolation of a novel ras-recision gene that is induced by hydrogen peroxide from a mouse osteoblastic cell line, MC3T3-E1.Q36681236
Production of immortalized distal respiratory epithelial cell lines from surfactant protein C/simian virus 40 large tumor antigen transgenic miceQ36686163
Purification and characterization of a fatty acid-activated protein kinase (PKN) from rat testisQ36691956
Cloning and expression of the alveolar type II cell P2u-purinergic receptorQ36711108
Subtractive hybridization cloning of novel genes differentially expressed during intestinal developmentQ36736649
Alpha2-adrenergic receptor-mediated release of lysophosphatidic acid by adipocytes. A paracrine signal for preadipocyte growthQ37380211
Generation of lyso-phospholipids from surfactant in acute lung injury is mediated by type-II phospholipase A2 and inhibited by a direct surfactant protein A-phospholipase A2 protein interactionQ37387430
Phosphatidate-dependent protein phosphorylationQ37548665
Isolation and culture of alveolar type II cellsQ37920407
Functional roles for fatty acylated amino-terminal domains in subcellular localizationQ38614617
The biosynthesis of glycerides by mitochondria from rat liver. The requirement for a soluble proteinQ39255332
Inositol trisphosphate and diacylglycerol: two interacting second messengersQ39664919
Intracellular translocation of phosphatidate phosphohydrolase and its possible role in the control of glycerolipid synthesisQ40081072
Pulmonary phosphatidic acid phosphatase. Properties of membrane-bound phosphatidate-dependent phosphatidic acid phosphatase in rat lungQ40257699
Phosphatidohydrolase activity in a solubilized preparation from rat brain particulate fractionQ40336618
Factors influencing efficacy of exogenous surfactant in acute lung injury.Q40466341
Extracellular metabolism of pulmonary surfactant: the role of a new serine proteaseQ40543188
Generation of an immortal differentiated lung type-II epithelial cell line from the adult H-2K(b)tsA58 transgenic mouseQ40860365
Glycosphingolipids are not essential for formation of detergent-resistant membrane rafts in melanoma cells. methyl-beta-cyclodextrin does not affect cell surface transport of a GPI-anchored proteinQ40917288
Regulation of cyclooxygenase-2 expression by phosphatidate phosphohydrolase in human amnionic WISH cellsQ40928810
Reduction of caveolin 1 gene expression in lung carcinoma cell linesQ40970296
Proinflammatory macrophage-activating properties of the novel phospholipid diacylglycerol pyrophosphate.Q40985562
Heparin-binding EGF-like growth factor is a mitogen for rat alveolar type II cellsQ41119113
Nuclear translocation of RhoA mediates the mitogen-induced activation of phospholipase D involved in nuclear envelope signal transductionQ41127011
Regulation of phosphatidic acid phosphohydrolase by epidermal growth factor. Reduced association with the EGF receptor followed by increased association with protein kinase CepsilonQ41150470
In vitro and in vivo gene transfer to pulmonary cells mediated by cationic liposomes.Q41206351
A phospholipase D-mediated pathway for generating diacylglycerol in nuclei from Madin-Darby canine kidney cellsQ41344806
Phosphatidic acid activation of protein kinase C-zeta overexpressed in COS cells: comparison with other protein kinase C isotypes and other acidic lipidsQ41410908
New developments in phospholipase D.Q41503616
Regulation of Raf-1 kinase by interaction with the lipid second messenger, phosphatidic acidQ41505368
Cyclin A expression in normal and transformed alveolar epithelial cellsQ41536970
Structure of detergent-resistant membrane domains: does phase separation occur in biological membranes?Q41641699
Induction of A- and D-type cyclins and cdc2 kinase activity during recovery from short-term hyperoxic lung injuryQ41665412
Ceramide path in human lung cell deathQ41727820
Cloning, differential regulation and tissue distribution of alternatively spliced isoforms of ADP-ribosylation-factor-dependent phospholipase D from rat liverQ42106122
Identification of structurally important domains of lipid phosphate phosphatase-1: implications for its sites of actionQ42158591
Lysophosphatidate-induced cell proliferation: identification and dissection of signaling pathways mediated by G proteins.Q42160798
Lysophosphatidic acid activation of phosphatidylcholine-hydrolysing phospholipase D and actin polymerization by a pertussis toxin-sensitive mechanismQ42160836
Diacylglycerol kinase epsilon, but not zeta, selectively removes polyunsaturated diacylglycerol, inducing altered protein kinase C distribution in vivo.Q42480957
Bombesin stimulates distinct time-dependent changes in the sn-1,2-diradylglycerol molecular species profile from Swiss 3T3 fibroblasts as analysed by 3,5-dinitrobenzoyl derivatization and h.p.l.c. separationQ42509622
Mouse model for lung tumorigenesis through Cre/lox controlled sporadic activation of the K-Ras oncogeneQ42661743
Physical association with ras enhances activation of membrane-bound raf (RafCAAX).Q42801543
p42/44 MAP kinase-dependent and -independent signaling pathways regulate caveolin-1 gene expression. Activation of Ras-MAP kinase and protein kinase a signaling cascades transcriptionally down-regulates caveolin-1 promoter activityQ42809229
Localization of phospholipase D in detergent-insoluble, caveolin-rich membrane domains. Modulation by caveolin-1 expression and caveolin-182-101.Q42820574
The effects of Triton X-100 and chlorpromazine on the Mg2+-dependent and Mg2+-independent phosphatidate phosphohydrolase activities of rat lungQ42836674
Ras GTPase-activating protein physically associates with mitogenically active phospholipidsQ43182913
Phospholipase D2 activity suppresses hydrogen peroxide-induced apoptosis in PC12 cellsQ43505979
Phospholipase D activation by norepinephrine is mediated by 12(s)-, 15(s)-, and 20-hydroxyeicosatetraenoic acids generated by stimulation of cytosolic phospholipase a2. tyrosine phosphorylation of phospholipase d2 in response to norepinephrineQ43560047
Effects of phorbol-12,13-diesters on prostaglandin production and phospholipase activity in canine kidney (MDCK) cellsQ43570080
Site- and time-specific gene targeting in the mouseQ43591560
Loss of caveolae, vascular dysfunction, and pulmonary defects in caveolin-1 gene-disrupted miceQ29615180
Functions of lipid rafts in biological membranesQ29616845
Endophilin I mediates synaptic vesicle formation by transfer of arachidonate to lysophosphatidic acid.Q30175352
Lipid phosphate phosphohydrolase-1 degrades exogenous glycerolipid and sphingolipid phosphate estersQ30708920
Requirements and effects of palmitoylation of rat PLD1.Q31717168
Caveolae and their coat proteins, the caveolins: from electron microscopic novelty to biological launching pad.Q31911842
Caveolin and its cellular and subcellular immunolocalisation in lung alveolar epithelium: implications for alveolar epithelial type I cell function.Q31916421
Molecular mechanisms underlying endocytosis and sorting of ErbB receptor tyrosine kinasesQ32062433
Phospholipase D, tumor promoters, proliferation and prostaglandinsQ33178715
Signalling via caveolin: involvement in the cross-talk between phosphoinositolglycans and insulinQ33181719
Phospholipase D as an effector for ADP-ribosylation factor in the regulation of vesicular traffic.Q33652673
Detergent-insoluble glycosphingolipid/cholesterol-rich membrane domains, lipid rafts and caveolae (review).Q33694188
Sphingosine-1-phosphate: extracellular mediator or intracellular second messenger?Q33697778
Regulation of phospholipase D.Q33698777
Regulation of phospholipase D by phosphorylation-dependent mechanisms.Q33698782
Mammalian phospholipase D structure and regulationQ33698799
Phospholipase D and membrane traffic. Potential roles in regulated exocytosis, membrane delivery and vesicle buddingQ33698823
Localization and possible functions of phospholipase D isozymesQ33698828
A novel protein kinase target for the lipid second messenger phosphatidic acidQ33698833
Endothelium-derived nitric oxide and vascular physiology and pathologyQ33708030
Lipid translocation across the plasma membrane of mammalian cellsQ33710622
Caveolins, liquid-ordered domains, and signal transductionQ33752828
The GPI biosynthetic pathway as a therapeutic target for African sleeping sickness.Q33778459
Bioactive lysophospholipids and their G protein-coupled receptorsQ33783568
A proposed model for the assembly of chylomicronsQ33783778
Calcium signal transduction from caveolaeQ33822066
Phospholipase A2 in eicosanoid generationQ33836689
Mechanisms of nuclear translocation of insulinQ33875142
CtBP/BARS induces fission of Golgi membranes by acylating lysophosphatidic acidQ33882728
Induction of endothelial cell chemotaxis by sphingosine 1-phosphate and stabilization of endothelial monolayer barrier function by lysophosphatidic acid, potential mediators of hematopoietic angiogenesisQ33887527
Platelet-activating factor and related lipid mediatorsQ33916020
De novo formation of caveolae in lymphocytes by expression of VIP21-caveolin.Q33916325
A gonadotropin-releasing hormone-responsive phosphatase hydrolyses lysophosphatidic acid within the plasma membrane of ovarian cancer cellsQ33918778
Recent advances in the regulation of cytosolic phospholipase A(2).Q33927870
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)L1-23
P577publication date2003-01-01
P1433published inAmerican Journal of Physiology - Lung Cellular and Molecular PhysiologyQ4352992
P1476titlePulmonary phosphatidic acid phosphatase and lipid phosphate phosphohydrolase
P478volume284

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