Flow-dependent regulation of endothelial nitric oxide synthase: role of protein kinases

scientific article

Flow-dependent regulation of endothelial nitric oxide synthase: role of protein kinases is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P356DOI10.1152/AJPCELL.00122.2003
P698PubMed publication ID12900384

P50authorYong Chool BooQ40175584
Hanjoong JoQ40201403
P2860cites workRole of c-Src in regulation of endothelial nitric oxide synthase expression during exercise trainingQ44321377
Neuronal nitric-oxide synthase interaction with calmodulin-troponin C chimeras.Q48493450
Nitric oxide synthases: structure, function and inhibitionQ55951119
Regulation of endothelium-derived nitric oxide production by the protein kinase AktQ22010149
Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylationQ22010150
Nitric oxide down-regulates MKP-3 mRNA levels: involvement in endothelial cell protection from apoptosisQ22254259
NOSIP, a novel modulator of endothelial nitric oxide synthase activityQ24290718
Endothelial nitric oxide synthase interactions with G-protein-coupled receptorsQ24531842
Signal transduction of eNOS activationQ28145425
Pulmonary phosphatidic acid phosphatase and lipid phosphate phosphohydrolaseQ28216832
Regulation of endothelial nitric oxide synthase: location, location, locationQ28217344
Direct interaction of endothelial nitric-oxide synthase and caveolin-1 inhibits synthase activityQ28244026
Endothelial nitric oxide synthase is regulated by tyrosine phosphorylation and interacts with caveolin-1Q28296135
Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factorQ28299224
Nitric oxide inhibits tumor necrosis factor-alpha-induced apoptosis by reducing the generation of ceramideQ28344228
Transcriptional and posttranscriptional regulation of endothelial nitric oxide synthase expression by hydrogen peroxideQ28370621
Upregulation of superoxide dismutase and nitric oxide synthase mediates the apoptosis-suppressive effects of shear stress on endothelial cellsQ28371345
The Akt kinase signals directly to endothelial nitric oxide synthaseQ28609847
Reciprocal regulation of endothelial nitric-oxide synthase by Ca2+-calmodulin and caveolinQ28609899
The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholineQ29547539
Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxideQ29619956
Molecular cloning and characterization of the constitutive bovine aortic endothelial cell nitric oxide synthaseQ31172360
Estrogen induces the Akt-dependent activation of endothelial nitric-oxide synthase in vascular endothelial cellsQ31484668
Direct interaction between endothelial nitric-oxide synthase and dynamin-2. Implications for nitric-oxide synthase functionQ31713201
Identification of regulatory sites of phosphorylation of the bovine endothelial nitric-oxide synthase at serine 617 and serine 635.Q33184040
Endogenous nitric oxide synthesis: biological functions and pathophysiologyQ33814359
Phosphorylation of Thr(495) regulates Ca(2+)/calmodulin-dependent endothelial nitric oxide synthase activity.Q33950554
Nitric oxide reversibly inhibits seven members of the caspase family via S-nitrosylationQ34065605
Cellular signaling: pivoting around PDK-1.Q34073383
Interaction of heterotrimeric G13 protein with an A-kinase-anchoring protein 110 (AKAP110) mediates cAMP-independent PKA activationQ34100595
Functional interaction of endothelial nitric oxide synthase with a voltage-dependent anion channel.Q34191808
Flow-mediated endothelial mechanotransductionQ34648558
Hypercholesterolemia increases endothelial superoxide anion productionQ35610616
Nitric oxide decreases cytokine-induced endothelial activation. Nitric oxide selectively reduces endothelial expression of adhesion molecules and proinflammatory cytokinesQ35749970
Calmodulin is a subunit of nitric oxide synthase from macrophagesQ36231600
Phosphorylation and activation of cAMP-dependent protein kinase by phosphoinositide-dependent protein kinaseQ36278250
Regulation of endothelin 1 gene by fluid shear stress is transcriptionally mediated and independent of protein kinase C and cAMP.Q36388240
Nitric oxide synthases: which, where, how, and why?Q37374087
Purification and characterization of particulate endothelium-derived relaxing factor synthase from cultured and native bovine aortic endothelial cellsQ37628594
Disabling a C-terminal autoinhibitory control element in endothelial nitric-oxide synthase by phosphorylation provides a molecular explanation for activation of vascular NO synthesis by diverse physiological stimuli.Q38292157
Transactivation of vascular endothelial growth factor (VEGF) receptor Flk-1/KDR is involved in sphingosine 1-phosphate-stimulated phosphorylation of Akt and endothelial nitric-oxide synthase (eNOS).Q38363037
Physiological phosphorylation of protein kinase A at Thr-197 is by a protein kinase A kinaseQ39574548
Nitric oxide synthase: Aspects concerning structure and catalysisQ40393175
Localization of endothelial nitric-oxide synthase phosphorylated on serine 1179 and nitric oxide in Golgi and plasma membrane defines the existence of two pools of active enzyme.Q40765690
Sphingosine 1-phosphate and isoform-specific activation of phosphoinositide 3-kinase beta. Evidence for divergence and convergence of receptor-regulated endothelial nitric-oxide synthase signaling pathwaysQ40790165
Characterization of the roles of the 594-645 region in human endothelial nitric-oxide synthase in regulating calmodulin binding and electron transferQ40884539
Inhibitory interactions of the bradykinin B2 receptor with endothelial nitric-oxide synthaseQ41011014
Dynamic activation of endothelial nitric oxide synthase by Hsp90.Q41044129
Blood radicals: reactive nitrogen species, reactive oxygen species, transition metal ions, and the vascular systemQ41154272
Chronic treatment with polyethylene-glycolated superoxide dismutase partially restores endothelium-dependent vascular relaxations in cholesterol-fed rabbitsQ41169284
Identification, characterization, and comparison of the calmodulin-binding domains of the endothelial and inducible nitric oxide synthasesQ41215964
PI3K: downstream AKTion blocks apoptosisQ41351876
Calcium-dependent and calcium-independent activation of the endothelial NO synthaseQ41534240
Autoinhibition of endothelial nitric-oxide synthase. Identification of an electron transfer control elementQ41665327
Angioscopic coronary macromorphology in patients with acute coronary disordersQ41839591
Flow modulation of agonist (ATP)-response (Ca2+) coupling in vascular endothelial cellsQ42471422
Protein kinase C modulates receptor-independent activation of endothelial nitric oxide synthaseQ42475887
Shear stress elevates endothelial cGMP. Role of a potassium channel and G protein couplingQ42508047
Intracellular pH and tyrosine phosphorylation but not calcium determine shear stress-induced nitric oxide production in native endothelial cellsQ42517024
Modulation by peroxynitrite of Akt- and AMP-activated kinase-dependent Ser1179 phosphorylation of endothelial nitric oxide synthase.Q42523433
Ca2+-independent activation of the endothelial nitric oxide synthase in response to tyrosine phosphatase inhibitors and fluid shear stressQ42543420
Suppression of apoptosis by nitric oxide via inhibition of interleukin-1beta-converting enzyme (ICE)-like and cysteine protease protein (CPP)-32-like proteasesQ42947736
Heat shock protein 90 mediates the balance of nitric oxide and superoxide anion from endothelial nitric-oxide synthaseQ43559219
Sphingosine 1-phosphate and activation of endothelial nitric-oxide synthase. differential regulation of Akt and MAP kinase pathways by EDG and bradykinin receptors in vascular endothelial cellsQ43559410
Sphingosine 1-phosphate activates Akt, nitric oxide production, and chemotaxis through a Gi protein/phosphoinositide 3-kinase pathway in endothelial cellsQ43559665
Coordinated control of endothelial nitric-oxide synthase phosphorylation by protein kinase C and the cAMP-dependent protein kinaseQ43568413
Cyclic AMP-independent activation of protein kinase A by vasoactive peptidesQ43594112
Reciprocal phosphorylation and regulation of endothelial nitric-oxide synthase in response to bradykinin stimulationQ43599368
Hsp90 ensures the transition from the early Ca2+-dependent to the late phosphorylation-dependent activation of the endothelial nitric-oxide synthase in vascular endothelial growth factor-exposed endothelial cellsQ43653363
Protein kinase B/Akt activates c-Jun NH(2)-terminal kinase by increasing NO production in response to shear stress.Q43745423
Shear stress regulates endothelial nitric oxide synthase expression through c-Src by divergent signaling pathwaysQ43805171
Shear stress stimulates phosphorylation of endothelial nitric-oxide synthase at Ser1179 by Akt-independent mechanisms: role of protein kinase A.Q43812771
Hydrogen peroxide activates endothelial nitric-oxide synthase through coordinated phosphorylation and dephosphorylation via a phosphoinositide 3-kinase-dependent signaling pathway.Q43823904
Dephosphorylation of endothelial nitric-oxide synthase by vascular endothelial growth factor. Implications for the vascular responses to cyclosporin A.Q44018080
Shear stress stimulates phosphorylation of eNOS at Ser(635) by a protein kinase A-dependent mechanismQ44182985
Akt-dependent phosphorylation of serine 1179 and mitogen-activated protein kinase kinase/extracellular signal-regulated kinase 1/2 cooperatively mediate activation of the endothelial nitric-oxide synthase by hydrogen peroxideQ44278276
P433issue3
P921main subjectendotheliumQ111140
P304page(s)C499-508
P577publication date2003-09-01
P1433published inAmerican Journal of Physiology - Cell PhysiologyQ2227080
P1476titleFlow-dependent regulation of endothelial nitric oxide synthase: role of protein kinases
P478volume285

Reverse relations

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