KPNB1, XPO7 and IPO8 Mediate the Translocation ofNF‐κB/p65 into the Nucleus

scientific article published on August 19, 2013

KPNB1, XPO7 and IPO8 Mediate the Translocation ofNF‐κB/p65 into the Nucleus is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1111/TRA.12097
P953full work available online athttps://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Ftra.12097
https://onlinelibrary.wiley.com/doi/pdf/10.1111/tra.12097
https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/tra.12097
P698PubMed publication ID23906023
P5875ResearchGate publication ID254263195

P2093author name stringHaiyan Zhang
Guoxin Wang
Suping Li
Biliang Zhang
Peizhou Liang
Shujie Cong
Yingyun Luo
P2860cites workA physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathwayQ21735927
Transport between the cell nucleus and the cytoplasmQ22065411
Mechanisms of Receptor-Mediated Nuclear Import and Nuclear ExportQ22065647
Identification of two novel RanGTP-binding proteins belonging to the importin beta superfamilyQ24290375
NF-{kappa}B is transported into the nucleus by importin {alpha}3 and importin {alpha}4Q24293000
Cloning of two novel human importin-alpha subunits and analysis of the expression pattern of the importin-alpha protein familyQ24311981
Rch1, a protein that specifically interacts with the RAG-1 recombination-activating proteinQ24312782
A novel class of RanGTP binding proteinsQ24316050
Export of importin alpha from the nucleus is mediated by a specific nuclear transport factorQ24316152
RAG-1 interacts with the repeated amino acid motif of the human homologue of the yeast protein SRP1Q24316431
Importin beta, transportin, RanBP5 and RanBP7 mediate nuclear import of ribosomal proteins in mammalian cellsQ24319791
Two different subunits of importin cooperate to recognize nuclear localization signals and bind them to the nuclear envelopeQ24320769
Importin 8 is a gene silencing factor that targets argonaute proteins to distinct mRNAsQ24321397
Cloning of a cDNA encoding a novel importin-alpha homologue, Qip1: discrimination of Qip1 and Rch1 from hSrp1 by their ability to interact with DNA helicase Q1/RecQLQ24324633
The importin beta/importin 7 heterodimer is a functional nuclear import receptor for histone H1.Q24534118
Evidence for distinct substrate specificities of importin alpha family members in nuclear protein importQ24554392
Exportin 7 defines a novel general nuclear export pathwayQ24563375
Nuclear targeting sequences--a consensus?Q27860997
A distinct nuclear import pathway used by ribosomal proteinsQ27929963
Yrb4p, a yeast ran-GTP-binding protein involved in import of ribosomal protein L25 into the nucleusQ27932000
NF-kappaB regulation in the immune systemQ28205043
Isolation of a protein that is essential for the first step of nuclear protein importQ28243173
Crosstalk in NF-κB signaling pathwaysQ29617418
NF-kappaB: a key role in inflammatory diseasesQ29617726
NF-kappa B: ten years afterQ29618566
The GTP-binding protein Ran/TC4 is required for protein import into the nucleusQ29620192
Identification of cytosolic factors required for nuclear location sequence-mediated binding to the nuclear envelopeQ29622845
STRADalpha regulates LKB1 localization by blocking access to importin-alpha, and by association with Crm1 and exportin-7.Q30441588
Role of importin alpha8, a new member of the importin alpha family of nuclear transport proteins, in early embryonic development in cattleQ33440177
Multiple signals converging on NF-kappaB.Q33597403
NF-kappaB family of transcription factors: central regulators of innate and adaptive immune functions.Q34720640
Preferential utilization of Imp7/8 in nuclear import of SmadsQ34783790
Nucleocytoplasmic transport: navigating the channelQ35092062
Crosstalk between the canonical NF-κB and Notch signaling pathways inhibits Pparγ expression and promotes pancreatic cancer progression in miceQ35578568
Importin beta: conducting a much larger cellular symphonyQ35938681
The direction of transport through the nuclear pore can be invertedQ36428044
Characterization and quantitation of NF-kappaB nuclear translocation induced by interleukin-1 and tumor necrosis factor-alpha. Development and use of a high capacity fluorescence cytometric system.Q36899057
Nucleocytoplasmic transport of proteinsQ37087415
Importins and beyond: non-conventional nuclear transport mechanismsQ37528567
I kappa B interacts with the nuclear localization sequences of the subunits of NF-kappa B: a mechanism for cytoplasmic retentionQ38325326
Cytoplasmic sequestration of rel proteins by IkappaBalpha requires CRM1-dependent nuclear exportQ39584943
NF-kappaB p52, RelB and c-Rel are transported into the nucleus via a subset of importin alpha moleculesQ39984698
Genome-wide mapping of RELA(p65) binding identifies E2F1 as a transcriptional activator recruited by NF-kappaB upon TLR4 activationQ40091968
Signaling molecules of the NF-kappa B pathway shuttle constitutively between cytoplasm and nucleus.Q42516012
A 65-kappaD subunit of active NF-kappaB is required for inhibition of NF-kappaB by I kappaB.Q45142085
The regulation and roles of Rel/NF-κB transcription factors during lymphocyte activationQ47933661
Requirement of the NF-κB pathway for induction of Wnt-5A by interleukin-1β in condylar chondrocytes of the temporomandibular joint: functional crosstalk between the Wnt-5A and NF-κB signaling pathwaysQ51553635
High-throughput RNAi screening in cultured cells: a user's guideQ52666716
Apoptotic histone modification inhibits nuclear transport by regulating RCC1.Q53433190
The interaction between importin-α and Nup153 promotes importin-α/β-mediated nuclear importQ83910788
P433issue11
P407language of work or nameEnglishQ1860
P921main subjectNF-κBQ411114
P304page(s)1132-1143
P577publication date2013-08-19
P1433published inTrafficQ1572846
P1476titleKPNB1, XPO7 and IPO8 mediate the translocation ofNF-κB/p65 into the nucleus
KPNB1, XPO7 and IPO8 Mediate the Translocation ofNF‐κB/p65 into the Nucleus
P478volume14

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cites work (P2860)
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Q35609624High expression of KPNA2 defines poor prognosis in patients with upper tract urothelial carcinoma treated with radical nephroureterectomy
Q35859525IPO3-mediated Nonclassical Nuclear Import of NF-κB Essential Modulator (NEMO) Drives DNA Damage-dependent NF-κB Activation
Q38906502Importin β1 targeting by hepatitis C virus NS3/4A protein restricts IRF3 and NF-κB signaling of IFNB1 antiviral response
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Q38857615KPNA2 Contributes to the Inflammatory Processes in Synovial Tissue of Patients with Rheumatoid Arthritis and SW982 Cells
Q55081473KPNB1 inhibition disrupts proteostasis and triggers unfolded protein response-mediated apoptosis in glioblastoma cells.
Q33779276KPNB1-mediated nuclear import is required for motility and inflammatory transcription factor activity in cervical cancer cells
Q53317062KPNβ1 promotes palmitate-induced insulin resistance via NF-κB signaling in hepatocytes
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Q59125995Mechanisms of NF-κB p65 and strategies for therapeutic manipulation
Q91994891NF-κB Signaling Pathways in Osteoarthritic Cartilage Destruction
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Q90041633USP22 promotes IRF3 nuclear translocation and antiviral responses by deubiquitinating the importin protein KPNA2
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