Evidence of a link between ubiquilin 2 and optineurin in amyotrophic lateral sclerosis

scientific article published on 14 November 2014

Evidence of a link between ubiquilin 2 and optineurin in amyotrophic lateral sclerosis is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1093/HMG/DDU575
P698PubMed publication ID25398946

P50authorDaisuke ItoQ30430138
Norihiro SuzukiQ30430157
P2093author name stringTakuya Yagi
Yoshihiro Nihei
Mayuko Osaka
P2860cites workCharacterization and dynamics of aggresome formation by a cytosolic GFP-chimeraQ42870983
Characterization of alternative isoforms and inclusion body of the TAR DNA-binding protein-43.Q42940304
Nuclear transport impairment of amyotrophic lateral sclerosis-linked mutations in FUS/TLS.Q52607544
Caveolin-Stabilized Membrane Domains as Multifunctional Transport and Sorting Devices in Endocytic Membrane TrafficQ57359930
Identification of ubiquilin, a novel presenilin interactor that increases presenilin protein accumulationQ24290515
Parkin accumulation in aggresomes due to proteasome impairmentQ24308757
Huntingtin is ubiquitinated and interacts with a specific ubiquitin-conjugating enzymeQ24311567
TBC1D14 regulates autophagosome formation via Rab11- and ULK1-positive recycling endosomesQ24324535
Ubiquilin and p97/VCP bind erasin, forming a complex involved in ERADQ24324707
Mutations in UBQLN2 cause dominant X-linked juvenile and adult-onset ALS and ALS/dementiaQ24600027
ALS-associated fused in sarcoma (FUS) mutations disrupt Transportin-mediated nuclear importQ24630100
Ubiquilin-1 is a molecular chaperone for the amyloid precursor proteinQ24634983
The hPLIC proteins may provide a link between the ubiquitination machinery and the proteasomeQ28138493
Aggresomes formed by alpha-synuclein and synphilin-1 are cytoprotectiveQ28185660
Null mutations in progranulin cause ubiquitin-positive frontotemporal dementia linked to chromosome 17q21Q28253639
Aggresomes: a cellular response to misfolded proteinsQ28292275
The role of autophagy during the early neonatal starvation periodQ29547489
Mutations of optineurin in amyotrophic lateral sclerosisQ29614836
Aggresomes, inclusion bodies and protein aggregationQ29615253
Regulation of endocytic trafficking of transferrin receptor by optineurin and its impairment by a glaucoma-associated mutantQ30493294
From UBA to UBX: new words in the ubiquitin vocabulary.Q34133094
Roles of ataxin-2 in pathological cascades mediated by TAR DNA-binding protein 43 (TDP-43) and Fused in Sarcoma (FUS)Q34304833
Diverse autophagosome membrane sources coalesce in recycling endosomes.Q34370963
Fractalkine attenuates excito-neurotoxicity via microglial clearance of damaged neurons and antioxidant enzyme heme oxygenase-1 expressionQ34503290
Molecular pathogenesis of seipin/BSCL2-related motor neuron diseasesQ34612571
Ubiquilin-1 regulates amyloid precursor protein maturation and degradation by stimulating K63-linked polyubiquitination of lysine 688Q36170580
Progranulin mutations and amyotrophic lateral sclerosis or amyotrophic lateral sclerosis-frontotemporal dementia phenotypesQ36227050
Enhanced aggregation of androgen receptor in induced pluripotent stem cell-derived neurons from spinal and bulbar muscular atrophyQ36708477
Kaposi's sarcoma-associated herpesvirus K7 protein targets a ubiquitin-like/ubiquitin-associated domain-containing protein to promote protein degradationQ37424480
Rab proteins mediate Golgi transport of caveola-internalized glycosphingolipids and correct lipid trafficking in Niemann-Pick C cellsQ39738033
Characterization of seipin/BSCL2, a protein associated with spastic paraplegia 17.Q39967409
Ubiquilin at a crossroads in protein degradation pathwaysQ42152457
Huntington's disease intranuclear inclusions contain truncated, ubiquitinated huntingtin proteinQ42598739
P433issue6
P921main subjectamyotrophic lateral sclerosisQ206901
P304page(s)1617-1629
P577publication date2014-11-14
P1433published inHuman Molecular GeneticsQ2720965
P1476titleEvidence of a link between ubiquilin 2 and optineurin in amyotrophic lateral sclerosis
P478volume24

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cites work (P2860)
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Q37052727Ubiquilin/Dsk2 promotes inclusion body formation and vacuole (lysosome)-mediated disposal of mutated huntingtin

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