| scholarly article | Q13442814 |
| P2093 | author name string | Dong Chen | |
| Pessin JE | |||
| Waters SB | |||
| Holt KH | |||
| P2860 | cites work | Signal transduction by tumor necrosis factor mediated by JNK protein kinases | Q24308037 |
| JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain | Q24308838 | ||
| A novel transforming protein (SHC) with an SH2 domain is implicated in mitogenic signal transduction | Q24338592 | ||
| Mammalian Ras interacts directly with the serine/threonine kinase Raf | Q27860833 | ||
| A divergence in the MAP kinase regulatory network defined by MEK kinase and Raf | Q28263195 | ||
| Guanine-nucleotide-releasing factor hSos1 binds to Grb2 and links receptor tyrosine kinases to Ras signalling | Q28268458 | ||
| Complexes of Ras.GTP with Raf-1 and mitogen-activated protein kinase kinase | Q28269621 | ||
| Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine | Q28287650 | ||
| A synthetic inhibitor of the mitogen-activated protein kinase cascade | Q28367955 | ||
| How MAP kinases are regulated | Q28609360 | ||
| MAPKs: new JNK expands the group | Q28611010 | ||
| Insulin-stimulated disassociation of the SOS-Grb2 complex | Q28615780 | ||
| Selective activation of the JNK signaling cascadeand c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs | Q29547308 | ||
| The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway | Q29614258 | ||
| Association of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation | Q29616396 | ||
| The stress-activated protein kinase subfamily of c-Jun kinases | Q29620001 | ||
| Differential activation of ERK and JNK mitogen-activated protein kinases by Raf-1 and MEKK | Q29620274 | ||
| Differential effects on cAMP on the MAP kinase cascade: evidence for a cAMP-insensitive step that can bypass Raf-1 | Q34450770 | ||
| Signal transduction via the MAP kinases: proceed at your own RSK. | Q36381460 | ||
| Raf-1 forms a stable complex with Mek1 and activates Mek1 by serine phosphorylation | Q36682210 | ||
| Reconstitution of the Raf-1-MEK-ERK signal transduction pathway in vitro | Q36824645 | ||
| Protein synthesis inhibitors reveal differential regulation of mitogen-activated protein kinase and stress-activated protein kinase pathways that converge on Elk-1. | Q40017118 | ||
| Epidermal growth factor induces phosphorylation of extracellular signal-regulated kinase 2 via multiple pathways | Q40656830 | ||
| Raf meets Ras: completing the framework of a signal transduction pathway | Q40682071 | ||
| Direct interaction between Ras and the kinase domain of mitogen-activated protein kinase kinase kinase (MEKK1). | Q41344713 | ||
| Insulin and epidermal growth factor influence guanine nucleotide-releasing factor by distinct mechanisms | Q41415010 | ||
| Anisomycin-activated protein kinases p45 and p55 but not mitogen-activated protein kinases ERK-1 and -2 are implicated in the induction of c-fos and c-jun | Q41431597 | ||
| Desensitization of Ras Activation by a Feedback Disassociation of the SOS-Grb2 Complex | Q42824495 | ||
| An osmosensing signal transduction pathway in mammalian cells | Q48080102 | ||
| P433 | issue | 11 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | phosphorylation | Q242736 |
| P304 | page(s) | 6328-6332 | |
| P577 | publication date | 1996-03-01 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | SOS phosphorylation and disassociation of the Grb2-SOS complex by the ERK and JNK signaling pathways | |
| P478 | volume | 271 |
| Q38220879 | "RAF" neighborhood: protein-protein interaction in the Raf/Mek/Erk pathway |
| Q52065307 | A computational study of feedback effects on signal dynamics in a mitogen-activated protein kinase (MAPK) pathway model. |
| Q28645870 | A molecular basis for insulin resistance. Elevated serine/threonine phosphorylation of IRS-1 and IRS-2 inhibits their binding to the juxtamembrane region of the insulin receptor and impairs their ability to undergo insulin-induced tyrosine phosphory |
| Q43116108 | A negative feedback signaling network underlies oncogene-induced senescence |
| Q92642778 | Adaptive Responses as Mechanisms of Resistance to BRAF Inhibitors in Melanoma |
| Q52684503 | Allele-Specific Mechanisms of Activation of MEK1 Mutants Determine Their Properties. |
| Q42449840 | Altered regulation of insulin signaling components in adipocytes of insulin-resistant type II diabetic Goto-Kakizaki rats |
| Q39630957 | Anisomycin selectively desensitizes signalling components involved in stress kinase activation and fos and jun induction |
| Q35887391 | Association of ERK2 mitogen-activated protein kinase with human immunodeficiency virus particles |
| Q36973111 | BRAF Mutants Evade ERK-Dependent Feedback by Different Mechanisms that Determine Their Sensitivity to Pharmacologic Inhibition |
| Q48034415 | Bidirectional regulation of p38 kinase and c-Jun N-terminal protein kinase by insulin-like growth factor-I. |
| Q41848152 | Biology using engineering tools: the negative feedback amplifier |
| Q28138256 | CAIR-1/BAG-3 forms an EGF-regulated ternary complex with phospholipase C-gamma and Hsp70/Hsc70 |
| Q40423778 | Cdc2-mediated inhibition of epidermal growth factor activation of the extracellular signal-regulated kinase pathway during mitosis |
| Q34361161 | Complexity of receptor tyrosine kinase signal processing |
| Q33508697 | Computational modelling of cancerous mutations in the EGFR/ERK signalling pathway |
| Q36313362 | Current challenges in quantitative modeling of epidermal growth factor signaling |
| Q47847884 | Difference between senescence-accelerated prone and resistant mice in response to insulin in the heart |
| Q33852403 | Discovery of novel anticancer therapeutics targeting the PI3K/Akt/mTOR pathway |
| Q24294914 | Disruption of CRAF-mediated MEK activation is required for effective MEK inhibition in KRAS mutant tumors |
| Q50538898 | Dissecting Cell-Fate Determination Through Integrated Mathematical Modeling of the ERK/MAPK Signaling Pathway. |
| Q44863595 | Dominant negative EGFR-CD533 and inhibition of MAPK modify JNK1 activation and enhance radiation toxicity of human mammary carcinoma cells.Miko |
| Q52328132 | Dynamics and control of the ERK signaling pathway: Sensitivity, bistability, and oscillations. |
| Q47246768 | Effects of ERK1/2 S-nitrosylation on ERK1/2 phosphorylation and cell survival in glioma cells |
| Q30176064 | Evidence that DOCK180 up-regulates signals from the CrkII-p130(Cas) complex |
| Q33364591 | Exact model reduction of combinatorial reaction networks |
| Q28265686 | Extracellular signal-regulated kinase activated by epidermal growth factor and cell adhesion interacts with and phosphorylates vinexin |
| Q37831109 | Feedback regulation of EGFR signalling: decision making by early and delayed loops. |
| Q37698293 | Four-dimensional dynamics of MAPK information processing systems. |
| Q34449946 | Functional roles of multiple feedback loops in extracellular signal-regulated kinase and Wnt signaling pathways that regulate epithelial-mesenchymal transition |
| Q42806282 | Hyperosmolality induces activation of cPKC and nPKC, a requirement for ERK1/2 activation in NIH/3T3 cells |
| Q43713575 | Hyperosmotic stress activates the insulin receptor in CHO cells |
| Q44679396 | Identification of novel ERK-mediated feedback phosphorylation sites at the C-terminus of B-Raf |
| Q33940377 | Identification of the mechanisms regulating the differential activation of the mapk cascade by epidermal growth factor and nerve growth factor in PC12 cells |
| Q24648281 | Identification of the mitogen-activated protein kinase phosphorylation sites on human Sos1 that regulate interaction with Grb2 |
| Q40751010 | In Hyperthermia Increased ERK and WNT Signaling Suppress Colorectal Cancer Cell Growth |
| Q30470683 | Insulin activates a PD 098059-sensitive kinase that is involved in the regulation of p70S6K and PHAS-I. |
| Q42830970 | Insulin induction of pip 92, CL-6, and novel mRNAs in rat hepatoma cells |
| Q48021735 | Insulin signal transduction through protein kinase cascades |
| Q34377093 | Integrating phosphoproteomics in systems biology |
| Q36254464 | Ligand-dependent responses of the ErbB signaling network: experimental and modeling analyses |
| Q73689121 | Ligation of membrane IgM stimulates a novel c-Jun amino-terminal domain kinase activity in Daudi human B cells |
| Q29615542 | MAP kinase signalling pathways in cancer |
| Q31834439 | Mast cell tryptase activates extracellular-regulated kinases (p44/p42) in airway smooth-muscle cells: importance of proteolytic events, time course, and role in mediating mitogenesis |
| Q52534273 | Mitogen-activated protein kinase and phosphorylation of connexin43 are not sufficient for the disruption of gap junctional communication by platelet-derived growth factor and tetradecanoylphorbol acetate. |
| Q92630701 | Mutations That Confer Drug-Resistance, Oncogenicity and Intrinsic Activity on the ERK MAP Kinases-Current State of the Art |
| Q45317149 | Negative feedback regulation of MAPK pathway |
| Q52666594 | New insights into RAS biology reinvigorate interest in mathematical modeling of RAS signaling. |
| Q34763366 | Opposite regulation of CD36 ubiquitination by fatty acids and insulin: effects on fatty acid uptake |
| Q28188974 | PAK1 phosphorylation of MEK1 regulates fibronectin-stimulated MAPK activation |
| Q28274831 | Phosphorylation of CrkII adaptor protein at tyrosine 221 by epidermal growth factor receptor |
| Q81581176 | Prediction and validation of the distinct dynamics of transient and sustained ERK activation |
| Q24316181 | Raf family kinases: old dogs have learned new tricks |
| Q43973600 | Ras Signaling Regulates Stem Cells and Amelogenesis in the Mouse Incisor |
| Q34101310 | Ras-activated endocytosis is mediated by the Rab5 guanine nucleotide exchange activity of RIN1. |
| Q24324545 | Regulation of Sos activity by intramolecular interactions |
| Q40891017 | Regulation of adenylyl cyclase, ERK1/2, and CREB by Gz following acute and chronic activation of the delta-opioid receptor |
| Q43667366 | Regulation of insulin-stimulated tyrosine phosphorylation of Shc and Shc/Grb2 association in liver, muscle, and adipose tissue of epinephrine- and streptozotocin-treated rats |
| Q41647860 | Regulation of the ERK subgroup of MAP kinase cascades through G protein-coupled receptors |
| Q90396914 | Role of c-Jun N-terminal Kinase (JNK) in Obesity and Type 2 Diabetes |
| Q37865381 | Roles of the Ras/Raf/MEK/ERK pathway in leukemia therapy. |
| Q36828963 | S-nitrosylation of ERK inhibits ERK phosphorylation and induces apoptosis |
| Q42827799 | Selective desensitization of growth factor signaling by cell adhesion to fibronectin |
| Q30176498 | Shrinkage-induced protein tyrosine phosphorylation in Chinese hamster ovary cells |
| Q40872114 | Signal transduction pathways and their relevance in human astrocytomas |
| Q41750250 | Signal transduction through MAP kinase cascades |
| Q41135422 | Signal-transducing protein phosphorylation cascades mediated by Ras/Rho proteins in the mammalian cell: the potential for multiplex signalling |
| Q34076266 | Spatial cycles in G-protein crowd control |
| Q39912075 | Spatio-temporal dynamics of a cell signal pathway with negative feedbacks: the MAPK/ERK pathway |
| Q41133285 | Syk-dependent and -independent signaling cascades in B cells elicited by osmotic and oxidative stress. |
| Q36716462 | System properties of ErbB receptor signaling for the understanding of cancer progression |
| Q37196175 | Systems-level interactions between insulin-EGF networks amplify mitogenic signaling. |
| Q37564511 | Targeting MAPK (Ras/ERK) and PI3K/Akt pathways in pituitary tumorigenesis |
| Q28277407 | Temporal analysis of phosphotyrosine-dependent signaling networks by quantitative proteomics |
| Q28294401 | Temporal regulation of EGF signalling networks by the scaffold protein Shc1 |
| Q37945533 | The "SWOT" of BRAF inhibition in melanoma: RAF inhibitors, MEK inhibitors or both? |
| Q77343239 | The p21-Ras signal transduction pathway and growth regulation in human high-grade gliomas |
| Q39763725 | The scaffold protein Shoc2/SUR-8 accelerates the interaction of Ras and Raf. |
| Q38097400 | The type 1 insulin-like growth factor receptor signalling system and targeted tyrosine kinase inhibition in cancer |
| Q35826480 | The vaccinia virus O1 protein is required for sustained activation of extracellular signal-regulated kinase 1/2 and promotes viral virulence |
| Q33323383 | Topological analysis of MAPK cascade for kinetic ErbB signaling |
| Q30175294 | Vinexin forms a signaling complex with Sos and modulates epidermal growth factor-induced c-Jun N-terminal kinase/stress-activated protein kinase activities. |
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