| scholarly article | Q13442814 |
| P50 | author | Tilman Brummer | Q43375998 |
| P2093 | author name string | Michael Reth | |
| Yukiko Misawa | |||
| Heike Naegele | |||
| P2860 | cites work | The complete coding sequence of the human A-raf-1 oncogene and transforming activity of a human A-raf carrying retrovirus | Q22254864 |
| T cell receptor (TCR) interacting molecule (TRIM), a novel disulfide-linked dimer associated with the TCR-CD3-zeta complex, recruits intracellular signaling proteins to the plasma membrane | Q24319819 | ||
| Meaningful relationships: the regulation of the Ras/Raf/MEK/ERK pathway by protein interactions | Q24532168 | ||
| Serine and tyrosine phosphorylations cooperate in Raf-1, but not B-Raf activation | Q24534094 | ||
| Mutations of the BRAF gene in human cancer | Q27860760 | ||
| Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation | Q28131755 | ||
| ERK2 mitogen-activated protein kinase binding, phosphorylation, and regulation of the PDE4D cAMP-specific phosphodiesterases. The involvement of COOH-terminal docking sites and NH2-terminal UCR regions | Q28145238 | ||
| Overlapping and specific functions of Braf and Craf-1 proto-oncogenes during mouse embryogenesis | Q28589059 | ||
| Purification of a Ras-dependent mitogen-activated protein kinase kinase kinase from bovine brain cytosol and its identification as a complex of B-Raf and 14-3-3 proteins | Q28609134 | ||
| PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo | Q28609356 | ||
| The docking protein FRS2alpha controls a MAP kinase-mediated negative feedback mechanism for signaling by FGF receptors | Q28609622 | ||
| Modulation of kinase activity and oncogenic properties by alternative splicing reveals a novel regulatory mechanism for B-Raf | Q28611463 | ||
| The structural basis for 14-3-3:phosphopeptide binding specificity | Q29547190 | ||
| Identification of a novel inhibitor of mitogen-activated protein kinase kinase | Q29616448 | ||
| Regulation of transcription by MAP kinase cascades | Q29618477 | ||
| Self-perpetuating states in signal transduction: positive feedback, double-negative feedback and bistability | Q29619706 | ||
| Mitogen-activated protein kinases: specific messages from ubiquitous messengers | Q30303652 | ||
| Mutational activation of c-raf-1 and definition of the minimal transforming sequence | Q30406579 | ||
| Raf-1 is a potential substrate for mitogen-activated protein kinase in vivo | Q30439640 | ||
| Inhibition of platelet-derived growth factor- and epidermal growth factor-mediated mitogenesis and signaling in 3T3 cells expressing delta Raf-1:ER, an estradiol-regulated form of Raf-1. | Q30450197 | ||
| Novel mechanisms of estrogen action in the brain: new players in an old story. | Q33635913 | ||
| Genetic analysis of B cell antigen receptor signaling | Q33652515 | ||
| Extracellular-signal-regulated kinase signalling in neurons | Q33745304 | ||
| Isotype-specific functions of Raf kinases | Q33783496 | ||
| Control of B cell development by Ras-mediated activation of Raf. | Q33887809 | ||
| Identification of the mechanisms regulating the differential activation of the mapk cascade by epidermal growth factor and nerve growth factor in PC12 cells | Q33940377 | ||
| Positive and negative regulation of Raf kinase activity and function by phosphorylation | Q34080535 | ||
| Serum- and glucocorticoid-inducible kinase SGK phosphorylates and negatively regulates B-Raf | Q34515800 | ||
| KSR is a scaffold required for activation of the ERK/MAPK module | Q35005553 | ||
| The complete coding sequence of the human raf oncogene and the corresponding structure of the c-raf-1 gene | Q36089427 | ||
| The cytoplasmic raf oncogene induces a neuronal phenotype in PC12 cells: a potential role for cellular raf kinases in neuronal growth factor signal transduction | Q36332163 | ||
| Raf-1 and p21v-ras cooperate in the activation of mitogen-activated protein kinase | Q36375189 | ||
| Involvement of guanosine triphosphatases and phospholipase C-gamma2 in extracellular signal-regulated kinase, c-Jun NH2-terminal kinase, and p38 mitogen-activated protein kinase activation by the B cell antigen receptor. | Q36401566 | ||
| Different protein tyrosine kinases are required for B cell antigen receptor-mediated activation of extracellular signal-regulated kinase, c-Jun NH2-terminal kinase 1, and p38 mitogen-activated protein kinase. | Q36401603 | ||
| Biochemical analysis of torso and D-raf during Drosophila embryogenesis: implications for terminal signal transduction | Q36661670 | ||
| The mouse B-raf gene encodes multiple protein isoforms with tissue-specific expression. | Q36681724 | ||
| Genomic organization and nucleotide sequence of the coding region of the chicken c-Rmil(B-raf-1) proto-oncogene | Q36764218 | ||
| A structural basis for substrate specificities of protein Ser/Thr kinases: primary sequence preference of casein kinases I and II, NIMA, phosphorylase kinase, calmodulin-dependent kinase II, CDK5, and Erk1. | Q36828945 | ||
| Inducible gene deletion reveals different roles for B-Raf and Raf-1 in B-cell antigen receptor signalling | Q39665762 | ||
| Inducible site-directed recombination in mouse embryonic stem cells | Q39715564 | ||
| An EBV-Genome-Negative Cell Line Established from an American Burkitt Lymphoma; Receptor Characteristics. EBV Infectibility and Permanent Conversion into EBV-Positive Sublines by <i>in vitro</i> Infection | Q40001995 | ||
| Inhibition of the MEK/ERK signaling pathway blocks a subset of B cell responses to antigen | Q40822193 | ||
| MEK1 mediates a positive feedback on Raf-1 activity independently of Ras and Src. | Q41085082 | ||
| Detection of ERK activation by a novel monoclonal antibody | Q41109336 | ||
| Mitogen-activated protein (MAP) kinase phosphorylation of MAP kinase kinase: determination of phosphorylation sites by mass spectrometry and site-directed mutagenesis | Q42487950 | ||
| Sequential modification of serines 621 and 624 in the Raf-1 carboxyl terminus produces alterations in its electrophoretic mobility. | Q42804533 | ||
| Rap1 mediates sustained MAP kinase activation induced by nerve growth factor | Q42830846 | ||
| The requirement of specific membrane domains for Raf-1 phosphorylation and activation | Q44226145 | ||
| SOS phosphorylation and disassociation of the Grb2-SOS complex by the ERK and JNK signaling pathways | Q45345641 | ||
| Disruption of the 14-3-3 binding site within the B-Raf kinase domain uncouples catalytic activity from PC12 cell differentiation | Q48899475 | ||
| In situ activation pattern of Drosophila EGF receptor pathway during development. | Q52192958 | ||
| Nerve Growth Factor-mediated Activation of the Mitogen-activated Protein (MAP) Kinase Cascade Involves a Signaling Complex Containing B-Raf and HSP90 | Q57711702 | ||
| Negative Modulation of Membrane Localization of the Raf-1 Protein Kinase by Hyperphosphorylation | Q58197205 | ||
| Pre-B cell receptor signaling mediates selective response to IL-7 at the pro-B to pre-B cell transition via an ERK/MAP kinase-dependent pathway | Q74840030 | ||
| P433 | issue | 55 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | phosphorylation | Q242736 |
| P304 | page(s) | 8823-8834 | |
| P577 | publication date | 2003-12-01 | |
| P1433 | published in | Oncogene | Q1568657 |
| P1476 | title | Identification of novel ERK-mediated feedback phosphorylation sites at the C-terminus of B-Raf | |
| P478 | volume | 22 |
| Q38220879 | "RAF" neighborhood: protein-protein interaction in the Raf/Mek/Erk pathway |
| Q43543397 | A Mek1-Mek2 heterodimer determines the strength and duration of the Erk signal |
| Q50292950 | Activated MAPKs phosphorylate BRAF |
| Q40347847 | B-Raf and C-Raf signaling investigated in a simplified model of the mitogenic kinase cascade |
| Q28235023 | B-Raf and Raf-1 are regulated by distinct autoregulatory mechanisms |
| Q48086875 | B-Raf is critical for MAPK activation during mitosis and is regulated in an M phase-dependent manner in Xenopus egg extracts |
| Q36418729 | BH3-only protein silencing contributes to acquired resistance to PLX4720 in human melanoma |
| Q33531822 | Cellular Ser/Thr-kinase assays using generic peptide substrates |
| Q42370777 | Combined MEK and ERK inhibition overcomes therapy-mediated pathway reactivation in RAS mutant tumors |
| Q47123785 | Combined targeting of Raf and Mek synergistically inhibits tumorigenesis in triple negative breast cancer model systems |
| Q38238604 | Consequences of feedback in signal transduction for targeted therapies. |
| Q48348507 | Discrete cytosolic macromolecular BRAF complexes exhibit distinct activities and composition |
| Q24314807 | Distinct requirement for an intact dimer interface in wild-type, V600E and kinase-dead B-Raf signalling |
| Q40281543 | Dynamic positive feedback phosphorylation of mixed lineage kinase 3 by JNK reversibly regulates its distribution to Triton-soluble domains |
| Q39561513 | ERK and PDE4 cooperate to induce RAF isoform switching in melanoma |
| Q48963518 | ERK1/2 protein and mRNA levels in human blood are linked to smoking behavior |
| Q37588717 | Emerging Raf inhibitors. |
| Q43148247 | Expression of excess receptors and negative feedback control of signal pathways are required for rapid activation and prompt cessation of signal transduction. |
| Q41521854 | Extracellular signal-regulated kinase 2 (ERK2) mediates phosphorylation and inactivation of nuclear interaction partner of anaplastic lymphoma kinase (NIPA) at G2/M. |
| Q52725941 | Extracellular-Regulated Kinases: Signaling From Ras to ERK Substrates to Control Biological Outcomes. |
| Q35730802 | Feedback regulation of lymphocyte signalling |
| Q30586789 | Frequency-modulated pulses of ERK activity transmit quantitative proliferation signals |
| Q40279488 | Functional analysis of the regulatory requirements of B-Raf and the B-Raf(V600E) oncoprotein |
| Q28578122 | Hierarchical scaffolding of an ERK1/2 activation pathway |
| Q33613978 | Impact of feedback phosphorylation and Raf heterodimerization on normal and mutant B-Raf signaling |
| Q38705548 | Inferring Intracellular Signal Transduction Circuitry from Molecular Perturbation Experiments |
| Q26741279 | JNK Signaling: Regulation and Functions Based on Complex Protein-Protein Partnerships |
| Q34491748 | Kidins220/ARMS binds to the B cell antigen receptor and regulates B cell development and activation |
| Q35693850 | Mechanism of RAF isoform switching induced by oncogenic RAS in melanoma |
| Q34341768 | Mechanisms of GnRH-induced extracellular signal-regulated kinase nuclear localization |
| Q60928825 | Mechanisms shaping the role of ERK1/2 in cellular senescence (Review) |
| Q45317149 | Negative feedback regulation of MAPK pathway |
| Q28079202 | Negative feedback regulation of the ERK1/2 MAPK pathway |
| Q40820078 | New targeted therapies for thyroid cancer |
| Q45218398 | Novel C-Raf phosphorylation sites: serine 296 and 301 participate in Raf regulation |
| Q37295744 | Phospho-proteomic analyses of B-Raf protein complexes reveal new regulatory principles. |
| Q38391612 | Phosphoproteome analysis of the MAPK pathway reveals previously undetected feedback mechanisms. |
| Q33690728 | Phosphorylation of c-Cbl and p85 PI3K driven by all-trans retinoic acid and CD38 depends on Lyn kinase activity. |
| Q46458312 | Positive regulation of A-RAF by phosphorylation of isoform-specific hinge segment and identification of novel phosphorylation sites |
| Q39647630 | RETRACTED: A novel class of specific Hsp90 small molecule inhibitors demonstrate in vitro and in vivo anti-tumor activity in human melanoma cells |
| Q24316181 | Raf family kinases: old dogs have learned new tricks |
| Q49874520 | Ras-Mediated Activation of the Raf Family Kinases |
| Q28580581 | Regulation and role of Raf-1/B-Raf heterodimerization |
| Q36738312 | Regulation of MAPKs by growth factors and receptor tyrosine kinases |
| Q37977165 | Regulation of MEK/ERK pathway output by subcellular localization of B-Raf |
| Q34966603 | Roles of the Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR pathways in controlling growth and sensitivity to therapy-implications for cancer and aging |
| Q37865381 | Roles of the Ras/Raf/MEK/ERK pathway in leukemia therapy. |
| Q37256977 | Signaling dynamics of the KSR1 scaffold complex |
| Q39406388 | Specifically targeting ERK1 or ERK2 kills melanoma cells |
| Q35848373 | Src inhibitors, PP2 and dasatinib, increase retinoic acid-induced association of Lyn and c-Raf (S259) and enhance MAPK-dependent differentiation of myeloid leukemia cells |
| Q39173195 | Strategies for Overcoming Resistance in Tumours Harboring BRAF Mutations |
| Q39536250 | Strong negative feedback from Erk to Raf confers robustness to MAPK signalling. |
| Q36716462 | System properties of ErbB receptor signaling for the understanding of cancer progression |
| Q35147151 | Targeted treatment of differentiated and medullary thyroid cancer |
| Q92663940 | Targeting Aberrant RAS/RAF/MEK/ERK Signaling for Cancer Therapy |
| Q33823577 | Targeting signal transduction pathways to eliminate chemotherapeutic drug resistance and cancer stem cells. |
| Q38212717 | The clinical development of MEK inhibitors |
| Q34572036 | The dual RAF/MEK inhibitor CH5126766/RO5126766 may be a potential therapy for RAS-mutated tumor cells |
| Q24314695 | The kinase Syk as an adaptor controlling sustained calcium signalling and B-cell development |
| Q33323383 | Topological analysis of MAPK cascade for kinetic ErbB signaling |
| Q40975668 | Wallenda/DLK protein levels are temporally downregulated by Tramtrack69 to allow R7 growth cones to become stationary boutons |
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