A realistic chance for gene therapy in the near future

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A realistic chance for gene therapy in the near future is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P6179Dimensions Publication ID1050301954
P356DOI10.1007/S00467-004-1680-0
P698PubMed publication ID15549408

P2093author name stringStefan Worgall
P2860cites workEvidence that bone morphogenetic protein 4 has multiple biological functions during kidney and urinary tract developmentQ24297582
Gene therapy of human severe combined immunodeficiency (SCID)-X1 diseaseQ28143064
LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1Q28210584
Fatal systemic inflammatory response syndrome in a ornithine transcarbamylase deficient patient following adenoviral gene transferQ28211178
Transcription start regions in the human genome are favored targets for MLV integrationQ29618456
A pilot study of in vivo liver-directed gene transfer with an adenoviral vector in partial ornithine transcarbamylase deficiencyQ33340517
Angiogenesis gene therapy: phase I assessment of direct intramyocardial administration of an adenovirus vector expressing VEGF121 cDNA to individuals with clinically significant severe coronary artery diseaseQ33869745
Molecular biology of adeno-associated virusesQ34002311
Clinical protocol. Gene therapy of Canavan disease: AAV-2 vector for neurosurgical delivery of aspartoacylase gene (ASPA) to the human brainQ34142832
AAV-mediated factor IX gene transfer to skeletal muscle in patients with severe hemophilia B.Q34168942
Antivector and antitransgene host responses in gene therapy.Q34183384
Accelerated vaccination for Ebola virus haemorrhagic fever in non-human primatesQ34220503
High-capacity 'gutless' adenoviral vectors.Q34431803
Hepatic and renal differentiation from blood-borne stem cells.Q34658441
Efficient mobilization and recruitment of marrow-derived endothelial and hematopoietic stem cells by adenoviral vectors expressing angiogenic factorsQ34658448
Therapeutic globin gene delivery using lentiviral vectors.Q34999167
Adeno-associated viruses undergo substantial evolution in primates during natural infectionsQ35022838
Current status of gene therapy for inherited lung diseasesQ35043830
Gene delivery using herpes simplex virus vectorsQ35062264
Gene therapy progress and prospects: therapeutic angiogenesis for limb and myocardial ischemiaQ35069562
Gene therapy using an adenovirus vector for apoptosis-related genes is a highly effective therapeutic modality for killing glioma cellsQ35090824
Progress and problems with the use of viral vectors for gene therapyQ35120176
Immune responses to replication-defective HSV-1 type vectors within the CNS: implications for gene therapyQ35131218
Bone marrow stem cells contribute to healing of the kidneyQ35133240
Renal gene transfer: nonviral approachesQ35141421
Applications of gene therapy to kidney diseaseQ35157973
From virus evolution to vector revolution: use of naturally occurring serotypes of adeno-associated virus (AAV) as novel vectors for human gene therapyQ35180997
Targeting retroviral and lentiviral vectors.Q35204394
Gene therapy for human malignant brain tumors.Q35210470
Comparison of replication-selective, oncolytic viruses for the treatment of human cancers.Q35545265
AAV-based gene transferQ35545274
Targeting survival: integration site selection by retroviruses and LTR-retrotransposonsQ35563809
AAV-mediated gene therapy for hemophiliaQ35577203
Recent advances in the development of HIV-1 vaccines using replication-incompetent adenovirus vectorsQ35640271
Gene delivery by lentivirus vectors an overview.Q35670108
Activation of the T-cell oncogene LMO2 after gene therapy for X-linked severe combined immunodeficiencyQ35676196
Gene therapy in renal diseases.Q35746821
Prospects and implications of using chromatin insulators in gene therapy and transgenesisQ35819847
Modification to the capsid of the adenovirus vector that enhances dendritic cell infection and transgene-specific cellular immune responsesQ36954135
Molecular therapy for renal diseasesQ39182534
Transfer of genes to humans: early lessons and obstacles to successQ40418899
AAV-mediated gene transfer to skeletal muscle.Q40588802
The basic science of gene therapyQ40907463
A replication-defective human adenovirus recombinant serves as a highly efficacious vaccine carrier.Q41203495
Long-term gene expression and phenotypic correction using adeno-associated virus vectors in the mammalian brainQ42280576
Safety of local delivery of low- and intermediate-dose adenovirus gene transfer vectors to individuals with a spectrum of morbid conditionsQ43846711
Correction of ADA-SCID by stem cell gene therapy combined with nonmyeloablative conditioningQ44044895
Gene therapy by transforming growth factor-beta receptor-IgG Fc chimera suppressed extracellular matrix accumulation in experimental glomerulonephritis.Q44266290
Phase I trial of intramuscular injection of a recombinant adeno-associated virus alpha 1-antitrypsin (rAAV2-CB-hAAT) gene vector to AAT-deficient adultsQ45676046
Immunity to adeno-associated virus serotype 2 delivered transgenes imparted by genetic predisposition to autoimmunityQ45698037
Transduction of renal cells in vitro and in vivo by adeno-associated virus gene therapy vectors.Q45747405
A serious adverse event after successful gene therapy for X-linked severe combined immunodeficiencyQ45857796
Gene therapy death prompts review of adenovirus vectorQ45864618
Clinical gene transfer studies for hemophilia B.Q45875059
Muscle-directed gene transfer and transient immune suppression result in sustained partial correction of canine hemophilia B caused by a null mutationQ45879591
Gene therapy with recombinant adenovirus vectors: evaluation of the host immune responseQ45882846
Sustained phenotypic correction of hemophilia B dogs with a factor IX null mutation by liver-directed gene therapyQ45884700
Genomic DNA transfer with a high-capacity adenovirus vector results in improved in vivo gene expression and decreased toxicity.Q45885499
Fas ligand gene transfer to renal allografts in rats: effects on allograft survivalQ46449268
Favorable effect of cotransfection with TGF-beta and CTLA4Ig of the donor kidney on allograft survivalQ47841574
Gene delivery using human cord blood-derived CD34+cells into inflamed glomeruli in NOD/SCID miceQ47860423
CTLA4Ig gene transfer prolongs survival and induces donor-specific tolerance in a rat renal allograftQ56906071
Non-invasive liposome-mediated gene delivery can correct the ion transport defect in cystic fibrosis mutant miceQ64377665
Detailed analysis of structures and formulations of cationic lipids for efficient gene transfer to the lungQ64382719
Administration of an adenovirus containing the human CFTR cDNA to the respiratory tract of individuals with cystic fibrosisQ71660966
Genetically modified bone marrow-derived vehicle cells site specifically deliver an anti-inflammatory cytokine to inflamed interstitium of obstructive nephropathyQ73311951
Human gene therapyQ95799789
P433issue2
P921main subjectgene therapyQ213901
P304page(s)118-124
P577publication date2004-11-10
P1433published inPediatric NephrologyQ15749796
P1476titleA realistic chance for gene therapy in the near future
P478volume20

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cites work (P2860)
Q34450895Acinar-to-ductal metaplasia induced by adenovirus-mediated pancreatic expression of Isl1.
Q35791792Adeno-Associated Virus-Mediated Gene Transfer to Renal Tubule Cells via a Retrograde Ureteral Approach
Q36600228Combining cell therapy and nanotechnology
Q36418370Gene therapeutics for periodontal regenerative medicine.
Q35770271Gene therapy of benign gynecological diseases
Q36583746Growth factor delivery for oral and periodontal tissue engineering
Q41853299Nucleofection mediates high-efficiency stable gene knockdown and transgene expression in human embryonic stem cells
Q39827069SHARP-2 gene silencing by lentiviral-based short hairpin RNA interference prolonged rat kidney transplant recipients' survival time
Q36972714The state of the art of adeno-associated virus-based vectors in gene therapy

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