| scholarly article | Q13442814 |
| P50 | author | Robert Tjian | Q906579 |
| Jennifer Doudna | Q56068 | ||
| Spencer C. Knight | Q67473082 | ||
| P2860 | cites work | Imaging Specific Genomic DNA in Living Cells | Q38825672 |
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| A Biophysical Model of CRISPR/Cas9 Activity for Rational Design of Genome Editing and Gene Regulation | Q28552981 | ||
| Cas9-crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria | Q29614420 | ||
| Dynamic imaging of genomic loci in living human cells by an optimized CRISPR/Cas system | Q29615782 | ||
| DNA targeting specificity of RNA-guided Cas9 nucleases | Q29615793 | ||
| Transcription regulation and animal diversity | Q29618752 | ||
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| Cas9-chromatin binding information enables more accurate CRISPR off-target prediction. | Q30279249 | ||
| Genome-wide analysis reveals characteristics of off-target sites bound by the Cas9 endonuclease. | Q30458169 | ||
| Live Cell Imaging Reveals the Dynamics of Telomerase Recruitment to Telomeres | Q30460277 | ||
| Visualization of repetitive DNA sequences in human chromosomes with transcription activator-like effectors | Q30560977 | ||
| Targeting and tracing of specific DNA sequences with dTALEs in living cells. | Q30575324 | ||
| In the right place at the right time: visualizing and understanding mRNA localization. | Q30656002 | ||
| CRISPRi-based genome-scale identification of functional long noncoding RNA loci in human cells | Q33573686 | ||
| Requirements for double-strand cleavage by chimeric restriction enzymes with zinc finger DNA-recognition domains | Q33786657 | ||
| Multiplexed and programmable regulation of gene networks with an integrated RNA and CRISPR/Cas toolkit in human cells. | Q33830378 | ||
| The HP1 protein family: getting a grip on chromatin | Q33885013 | ||
| Direct observation of R-loop formation by single RNA-guided Cas9 and Cascade effector complexes. | Q33919648 | ||
| Stimulation of homologous recombination through targeted cleavage by chimeric nucleases | Q33927812 | ||
| DNA interrogation by the CRISPR RNA-guided endonuclease Cas9. | Q33931841 | ||
| Programmable RNA recognition and cleavage by CRISPR/Cas9. | Q34042210 | ||
| Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex | Q34042665 | ||
| Epigenome editing by a CRISPR-Cas9-based acetyltransferase activates genes from promoters and enhancers. | Q34043681 | ||
| CASFISH: CRISPR/Cas9-mediated in situ labeling of genomic loci in fixed cells | Q34044790 | ||
| Rationally engineered Cas9 nucleases with improved specificity | Q34045530 | ||
| Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells | Q34093413 | ||
| Fluorescence in situ hybridization: past, present and future | Q34206080 | ||
| Transcription activator-like effector nucleases (TALENs): a highly efficient and versatile tool for genome editing | Q34333858 | ||
| Exploring the three-dimensional organization of genomes: interpreting chromatin interaction data | Q34343663 | ||
| Orthogonal Cas9 proteins for RNA-guided gene regulation and editing | Q34374050 | ||
| CRISPR interference (CRISPRi) for sequence-specific control of gene expression | Q34378409 | ||
| Topological organization of multichromosomal regions by the long intergenic noncoding RNA Firre | Q34400074 | ||
| CRISPR-based technologies: prokaryotic defense weapons repurposed | Q34405661 | ||
| Looping back to leap forward: transcription enters a new era | Q34412648 | ||
| Rational design of highly active sgRNAs for CRISPR-Cas9-mediated gene inactivation. | Q34436638 | ||
| Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation | Q34443093 | ||
| CRISPRdirect: software for designing CRISPR/Cas guide RNA with reduced off-target sites. | Q34448898 | ||
| GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases | Q34454104 | ||
| High-fidelity CRISPR-Cas9 nucleases with no detectable genome-wide off-target effects. | Q34507554 | ||
| Biology and Applications of CRISPR Systems: Harnessing Nature's Toolbox for Genome Engineering | Q34509196 | ||
| Targeted chromosomal cleavage and mutagenesis in Drosophila using zinc-finger nucleases | Q34615432 | ||
| Visualizing chromatin dynamics in interphase nuclei. | Q34656009 | ||
| Programmable RNA Tracking in Live Cells with CRISPR/Cas9. | Q34676404 | ||
| DNA repair mechanisms in dividing and non-dividing cells | Q34727858 | ||
| Engineering complex synthetic transcriptional programs with CRISPR RNA scaffolds | Q34979506 | ||
| Genome-wide detection of DNA double-stranded breaks induced by engineered nucleases. | Q35060760 | ||
| Dynamic regulation of transcriptional states by chromatin and transcription factors. | Q35068557 | ||
| Multicolor CRISPR labeling of chromosomal loci in human cells. | Q35190002 | ||
| A genome-wide analysis of Cas9 binding specificity using ChIP-seq and targeted sequence capture. | Q35237040 | ||
| Genome-wide specificity of DNA binding, gene regulation, and chromatin remodeling by TALE- and CRISPR/Cas9-based transcriptional activators | Q35876055 | ||
| Chromatin architecture reorganization during stem cell differentiation. | Q35889947 | ||
| Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9. | Q35896845 | ||
| Shelterin Protects Chromosome Ends by Compacting Telomeric Chromatin | Q35922154 | ||
| Cas9 Functionally Opens Chromatin | Q35975110 | ||
| CRISPRscan: designing highly efficient sgRNAs for CRISPR-Cas9 targeting in vivo | Q36109068 | ||
| Compact and highly active next-generation libraries for CRISPR-mediated gene repression and activation. | Q36142402 | ||
| In vivo localization of DNA sequences and visualization of large-scale chromatin organization using lac operator/repressor recognition | Q36257776 | ||
| RPA binds histone H3-H4 and functions in DNA replication-coupled nucleosome assembly | Q36261938 | ||
| GuideScan software for improved single and paired CRISPR guide RNA design | Q36298067 | ||
| High-throughput biochemical profiling reveals sequence determinants of dCas9 off-target binding and unbinding | Q36369721 | ||
| Genetics of global gene expression | Q36626609 | ||
| Beyond the sequence: cellular organization of genome function | Q36744492 | ||
| Fluorescent DNA nanotags: supramolecular fluorescent labels based on intercalating dye arrays assembled on nanostructured DNA templates. | Q36867814 | ||
| Expanding the CRISPR imaging toolset with Staphylococcus aureus Cas9 for simultaneous imaging of multiple genomic loci | Q36870491 | ||
| Conformational control of DNA target cleavage by CRISPR-Cas9. | Q36879255 | ||
| Nucleosomes impede Cas9 access to DNA in vivo and in vitro | Q36885171 | ||
| Nucleosome breathing and remodeling constrain CRISPR-Cas9 function | Q36936033 | ||
| An RNA-aptamer-based two-color CRISPR labeling system | Q36941440 | ||
| High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity | Q37196274 | ||
| CRISPR-Cas9 nuclear dynamics and target recognition in living cells. | Q37216431 | ||
| Real-time observation of DNA recognition and rejection by the RNA-guided endonuclease Cas9. | Q37263726 | ||
| Analysis of off-target effects of CRISPR/Cas-derived RNA-guided endonucleases and nickases. | Q37420333 | ||
| Fluorescence in situ hybridization: applications in cytogenetics and gene mapping | Q37778082 | ||
| Karyotyping human chromosomes by combinatorial multi-fluor FISH. | Q38507389 | ||
| Editing DNA Methylation in the Mammalian Genome | Q38744151 | ||
| Enhancing homology-directed genome editing by catalytically active and inactive CRISPR-Cas9 using asymmetric donor DNA. | Q38801430 | ||
| P433 | issue | 16 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | CRISPR | Q412563 |
| Cas9 | Q16965677 | ||
| CRISPR-Cas method | Q17310682 | ||
| P304 | page(s) | 4329-4337 | |
| P577 | publication date | 2018-02-28 | |
| P1433 | published in | Angewandte Chemie International Edition | Q62023953 |
| P1476 | title | Genomes in Focus: Development and Applications of CRISPR-Cas9 Imaging Technologies. | |
| P478 | volume | 57 |
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| Q90029724 | CRISPR/dual-FRET molecular beacon for sensitive live-cell imaging of non-repetitive genomic loci |
| Q90298764 | CRISPRdisco: An Automated Pipeline for the Discovery and Analysis of CRISPR-Cas Systems |
| Q89983035 | Cas9 interrogates DNA in discrete steps modulated by mismatches and supercoiling |
| Q64054399 | Circadian rhythms in the three-dimensional genome: implications of chromatin interactions for cyclic transcription |
| Q92557887 | Conditional Guide RNAs: Programmable Conditional Regulation of CRISPR/Cas Function in Bacterial and Mammalian Cells via Dynamic RNA Nanotechnology |
| Q89510923 | Embryo-Based Large Fragment Knock-in in Mammals: Why, How and What's Next |
| Q58580323 | Live imaging and tracking of genome regions in CRISPR/dCas9 knock-in mice |
| Q90570342 | Recent advances in CRISPR research |
| Q64096627 | The CRIPSR/Cas gene-editing system-an immature but useful toolkit for experimental and clinical medicine |
| Q92689577 | The CRISPR toolbox in medical mycology: State of the art and perspectives |
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