| scholarly article | Q13442814 |
| P356 | DOI | 10.1038/NI1104 |
| P698 | PubMed publication ID | 15311277 |
| P2093 | author name string | Bin Liu | |
| Hong Wu | |||
| Ke Shuai | |||
| Sheldon Mink | |||
| Paul W Dempsey | |||
| Kelly A Wong | |||
| Natalie Stein | |||
| Crescent Getman | |||
| P2860 | cites work | A transcriptional corepressor of Stat1 with an essential LXXLL signature motif | Q24290918 |
| Identification of a nuclear Stat1 protein tyrosine phosphatase | Q24302061 | ||
| Inhibition of Stat1-mediated gene activation by PIAS1 | Q24310082 | ||
| Members of the PIAS family act as SUMO ligases for c-Jun and p53 and repress p53 activity | Q24531180 | ||
| How cells respond to interferons | Q27861006 | ||
| Functional heterogeneity of small ubiquitin-related protein modifiers SUMO-1 versus SUMO-2/3 | Q28145507 | ||
| PIAS proteins promote SUMO-1 conjugation to STAT1 | Q28186494 | ||
| An E3-like factor that promotes SUMO conjugation to the yeast septins | Q28188846 | ||
| Involvement of PIAS1 in the sumoylation of tumor suppressor p53 | Q28189956 | ||
| PIASx is a transcriptional co-repressor of signal transducer and activator of transcription 4 | Q28201360 | ||
| Involvement of receptor-interacting protein 2 in innate and adaptive immune responses | Q28207221 | ||
| Activation of p53 by Protein Inhibitor of Activated Stat1 (PIAS1) | Q28215308 | ||
| Specific Inhibition of Stat3 Signal Transduction by PIAS3 | Q28255665 | ||
| Activation of transcription by IFN-gamma: tyrosine phosphorylation of a 91-kD DNA binding protein | Q28646262 | ||
| Stats: transcriptional control and biological impact | Q29547776 | ||
| Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease | Q29615967 | ||
| Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway | Q29615968 | ||
| Interferon-induced guanylate binding protein-1 (GBP-1) mediates an antiviral effect against vesicular stomatitis virus and encephalomyocarditis virus | Q33177702 | ||
| Interferon gamma receptor deficient mice are resistant to endotoxic shock | Q33492546 | ||
| Negative regulators of cytokine signal transduction | Q33754091 | ||
| Rta of murine gammaherpesvirus 68 reactivates the complete lytic cycle from latency. | Q33802415 | ||
| Central role for type I interferons and Tyk2 in lipopolysaccharide-induced endotoxin shock | Q33965313 | ||
| Cytokine signaling in 2002: new surprises in the Jak/Stat pathway | Q34126053 | ||
| Stat1-dependent and -independent pathways in IFN-gamma-dependent signaling | Q34584978 | ||
| IFNs and STATs in innate immunity to microorganisms | Q34647015 | ||
| Suppressors of cytokine signalling (SOCS) in the immune system | Q34716329 | ||
| Regulation of JAK-STAT signalling in the immune system | Q35605437 | ||
| Stat1-independent regulation of gene expression in response to IFN-gamma | Q36231607 | ||
| Biologic consequences of Stat1-independent IFN signaling. | Q36231950 | ||
| Induction of the Ly-6A/E gene by interferon alpha/beta and gamma requires a DNA element to which a tyrosine-phosphorylated 91-kDa protein binds | Q36432406 | ||
| Transcription program of murine gammaherpesvirus 68 | Q36524071 | ||
| Tyrosine phosphorylated p91 binds to a single element in the ISGF2/IRF-1 promoter to mediate induction by IFN alpha and IFN gamma, and is likely to autoregulate the p91 gene. | Q37627335 | ||
| SUMO modification of STAT1 and its role in PIAS-mediated inhibition of gene activation | Q40645462 | ||
| IRF3 mediates a TLR3/TLR4-specific antiviral gene program | Q40700858 | ||
| Phosphorylation of the Stat1 transactivation domain is required for full-fledged IFN-gamma-dependent innate immunity | Q44689531 | ||
| The STAT3 isoforms alpha and beta have unique and specific functions | Q44800009 | ||
| JAK/STAT signaling by cytokine receptors | Q46606420 | ||
| SOCS1/JAB is a negative regulator of LPS-induced macrophage activation | Q78518643 | ||
| SOCS-1 participates in negative regulation of LPS responses | Q78518680 | ||
| P433 | issue | 9 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 891-898 | |
| P577 | publication date | 2004-08-15 | |
| P1433 | published in | Nature Immunology | Q1071725 |
| P1476 | title | PIAS1 selectively inhibits interferon-inducible genes and is important in innate immunity. | |
| P478 | volume | 5 |
| Q64079625 | A Threshold Model for T-Cell Activation in the Era of Checkpoint Blockade Immunotherapy |
| Q80501651 | A peek at PIAS |
| Q36368258 | A role for protein inhibitor of activated STAT1 (PIAS1) in lipogenic regulation through SUMOylation-independent suppression of liver X receptors. |
| Q36985265 | AIRE regulates T-cell-independent B-cell responses through BAFF. |
| Q40113142 | ATM supports gammaherpesvirus replication by attenuating type I interferon pathway |
| Q43037981 | Activation of endoplasmic reticulum stress response by hepatitis viruses up-regulates protein phosphatase 2A. |
| Q35864559 | Age-Associated Failure To Adjust Type I IFN Receptor Signaling Thresholds after T Cell Activation |
| Q92445719 | Age-Dependent and -Independent Effects of Perivascular Adipose Tissue and Its Paracrine Activities during Neointima Formation |
| Q58763820 | Alcohol-induced autophagy via upregulation of PIASy promotes HCV replication in human hepatoma cells |
| Q36166518 | An In Vitro Förster Resonance Energy Transfer-Based High-Throughput Screening Assay for Inhibitors of Protein–Protein Interactions in SUMOylation Pathway |
| Q93270552 | An in vitro Förster resonance energy transfer-based high-throughput screening assay identifies inhibitors of SUMOylation E2 Ubc9 |
| Q47137780 | B Cell Receptor Activation and Chemical Induction Trigger Caspase-Mediated Cleavage of PIAS1 to Facilitate Epstein-Barr Virus Reactivation. |
| Q37146441 | Biology and significance of the JAK/STAT signalling pathways |
| Q27473235 | Blocking of Interferon-Induced Jak-Stat Signaling by Japanese Encephalitis Virus NS5 through a Protein Tyrosine Phosphatase-Mediated Mechanism |
| Q28570664 | CREB SUMOylation by the E3 ligase PIAS1 enhances spatial memory |
| Q37168136 | Computational models of the JAK1/2-STAT1 signaling |
| Q39386692 | Concepts and Methodologies to Study Protein SUMOylation: An Overview. |
| Q35880280 | Control of specificity and magnitude of NF-kappa B and STAT1-mediated gene activation through PIASy and PIAS1 cooperation |
| Q24644027 | DNA methylation represses IFN-gamma-induced and signal transducer and activator of transcription 1-mediated IFN regulatory factor 8 activation in colon carcinoma cells |
| Q30982143 | Deficiency of the dual ubiquitin/SUMO ligase Topors results in genetic instability and an increased rate of malignancy in mice |
| Q34751430 | Development of FRET assay into quantitative and high-throughput screening technology platforms for protein-protein interactions |
| Q28475642 | Ebola Zaire virus blocks type I interferon production by exploiting the host SUMO modification machinery |
| Q60306477 | Expression analysis of protein inhibitor of activated STAT (PIAS) genes in IFNβ-treated multiple sclerosis patients |
| Q46691163 | FLI-1 functionally interacts with PIASxalpha, a member of the PIAS E3 SUMO ligase family. |
| Q54243187 | Flavivirus internalization is regulated by a size-dependent endocytic pathway |
| Q34305645 | Functional reconstitution of a tunable E3-dependent sumoylation pathway in Escherichia coli. |
| Q24539130 | GPX-Macrophage Expression Atlas: a database for expression profiles of macrophages challenged with a variety of pro-inflammatory, anti-inflammatory, benign and pathogen insults |
| Q64163827 | Galectin-3 promotes Aβ oligomerization and Aβ toxicity in a mouse model of Alzheimer’s disease |
| Q41989639 | Gamma interferon-induced interferon regulatory factor 1-dependent antiviral response inhibits vaccinia virus replication in mouse but not human fibroblasts |
| Q37307906 | Genetic polymorphisms, their allele combinations and IFN-beta treatment response in Irish multiple sclerosis patients |
| Q34552627 | Glucocorticoid-induced S-adenosylmethionine enhances the interferon signaling pathway by restoring STAT1 protein methylation in hepatitis B virus-infected cells |
| Q38613608 | HCV Innate Immune Responses |
| Q33315750 | Identification of a new site of sumoylation on Tel (ETV6) uncovers a PIAS-dependent mode of regulating Tel function. |
| Q91330071 | Inducible degradation of lncRNA Sros1 promotes IFN-γ-mediated activation of innate immune responses by stabilizing Stat1 mRNA |
| Q41282268 | Innate immunity in pluripotent human cells: attenuated response to interferon-β. |
| Q92296644 | Interaction of PIAS1 with PRRS virus nucleocapsid protein mediates NF-κB activation and triggers proinflammatory mediators during viral infection |
| Q28270336 | Interferons, immunity and cancer immunoediting |
| Q36617091 | Interleukins and STAT signaling |
| Q38102561 | Interplay between viruses and host sumoylation pathways |
| Q92012490 | JAK-STAT Signaling: A Double-Edged Sword of Immune Regulation and Cancer Progression |
| Q34740192 | Listeria monocytogenes Infection Induces Prosurvival Metabolic Signaling in Macrophages |
| Q24316163 | MDA5 is SUMOylated by PIAS2β in the upregulation of Type I interferon signaling |
| Q38793618 | Macrophage polarization in response to oral commensals and pathogens |
| Q43253103 | Mapping of Char10, a novel malaria susceptibility locus on mouse chromosome 9. |
| Q39190119 | Mechanisms and consequences of Jak-STAT signaling in the immune system. |
| Q37311038 | Mechanisms of Signal Transduction from Receptors of Type I and Type II Cytokines. |
| Q46656248 | Modification of the Stat1 SH2 domain broadly improves interferon efficacy in proportion to p300/CREB-binding protein coactivator recruitment |
| Q40318695 | Modulation of the activation of Stat1 by the interferon-gamma receptor complex |
| Q58883554 | Molecular mechanisms underlying the synergistic induction of CXCL10 by LPS and IFN-γ in human neutrophils |
| Q48375685 | NMDA receptor signaling mediates the expression of protein inhibitor of activated STAT1 (PIAS1) in rat hippocampus |
| Q33714545 | Negative regulation of NF-kappaB signaling by PIAS1. |
| Q36231107 | Negative regulation of cytokine and TLR signalings by SOCS and others |
| Q81133805 | Negative regulation of cytokine signaling |
| Q24816896 | Negative regulation of cytokine signaling and immune responses by SOCS proteins |
| Q34249505 | Negative regulation of the interferon response by an interferon-induced long non-coding RNA |
| Q34858737 | New regulators of NF-kappaB in inflammation |
| Q38789307 | Novel Role for Protein Inhibitor of Activated STAT 4 (PIAS4) in the Restriction of Herpes Simplex Virus 1 by the Cellular Intrinsic Antiviral Immune Response |
| Q34485736 | Novel role and mechanism of protein inhibitor of activated STAT1 in spatial learning |
| Q28248545 | PIAS proteins: pleiotropic interactors associated with SUMO |
| Q36984471 | PIAS1 Promotes Lymphomagenesis through MYC Upregulation |
| Q37088539 | PIAS1 Regulates Mutant Huntingtin Accumulation and Huntington's Disease-Associated Phenotypes In Vivo |
| Q38797348 | PIAS1 SUMO ligase regulates the self-renewal and differentiation of hematopoietic stem cells |
| Q34076409 | PIAS1 and STAT-3 impair the tumoricidal potential of IFN-γ-stimulated mouse dendritic cells generated with IL-15. |
| Q35107382 | PIAS1 regulates breast tumorigenesis through selective epigenetic gene silencing |
| Q34624300 | PIASy inhibits virus-induced and interferon-stimulated transcription through distinct mechanisms. |
| Q38092800 | PML Degradation: Multiple Ways to Eliminate PML. |
| Q36791361 | PPARs and molecular mechanisms of transrepression |
| Q39896633 | PRMT1-mediated arginine methylation of PIAS1 regulates STAT1 signaling |
| Q37356528 | Pharmacogenomics of IFN-beta in multiple sclerosis: towards a personalized medicine approach |
| Q42721929 | Pias1 is essential for erythroid and vascular development in the mouse embryo. |
| Q33830595 | Pias3 is necessary for dorso-ventral patterning and visual response of retinal cones but is not required for rod photoreceptor differentiation |
| Q89185950 | Post-Receptor Inhibitors of the GHR-JAK2-STAT Pathway in the Growth Hormone Signal Transduction |
| Q91340499 | Protein inhibitor of activated STAT1 (PIAS1) inhibits IRF8 activation of Epstein-Barr virus lytic gene expression |
| Q33267059 | Protein inhibitor of activated STAT1 interacts with and up-regulates activities of the pro-proliferative transcription factor Krüppel-like factor 5. |
| Q38125942 | Protein sumoylation in brain development, neuronal morphology and spinogenesis. |
| Q37224188 | Protein tyrosine phosphatases PTP-1B and TC-PTP play nonredundant roles in macrophage development and IFN-gamma signaling |
| Q36003873 | Protein-tyrosine phosphatases are involved in interferon resistance associated with insulin resistance in HepG2 cells and obese mice |
| Q36237663 | Reactive Oxygen Species, SUMOylation, and Endothelial Inflammation |
| Q38222709 | Regulation of NF-κB by TNF family cytokines |
| Q28297056 | Regulation of cytokine signaling pathways by PIAS proteins |
| Q28264801 | Regulation of gene-activation pathways by PIAS proteins in the immune system |
| Q24329099 | Regulation of protein tyrosine phosphatase 1B by sumoylation |
| Q36808685 | Regulation of the sumoylation system in gene expression |
| Q37902868 | Return to homeostasis: downregulation of NF-κB responses |
| Q40300400 | S-Adenosylmethionine and betaine correct hepatitis C virus induced inhibition of interferon signaling in vitro |
| Q44227187 | SUMO E3 ligases are expressed in the retina and regulate SUMOylation of the metabotropic glutamate receptor 8b. |
| Q38132691 | SUMO rules: regulatory concepts and their implication in neurologic functions. |
| Q34400369 | SUMO--a post-translational modification with therapeutic potential? |
| Q28243325 | SUMO: a history of modification |
| Q24318593 | SUMOylation of Blimp-1 is critical for plasma cell differentiation |
| Q36048656 | Signal transducer and activator of transcription (STAT) signalling and T-cell lymphomas. |
| Q37101568 | Signal transducer and activator of transcription 1 (STAT1) gain-of-function mutations and disseminated coccidioidomycosis and histoplasmosis |
| Q37859135 | Signal transducers and activators of transcription—from cytokine signalling to cancer biology |
| Q37392596 | Small ubiquitin-like modifiers in cellular malignancy and metastasis |
| Q43286701 | Small ubiquitin-related modifier paralogs are indispensable but functionally redundant during early development of zebrafish |
| Q36006811 | Smurf1 Protein Negatively Regulates Interferon-γ Signaling through Promoting STAT1 Protein Ubiquitination and Degradation |
| Q41939510 | Spatial interplay between PIASy and FIP200 in the regulation of signal transduction and transcriptional activity |
| Q40252886 | Stat1 and SUMO modification |
| Q36846094 | Sumo-1 function is dispensable in normal mouse development |
| Q40875210 | Sumoylation coordinates the repression of inflammatory and anti-viral gene-expression programs during innate sensing |
| Q34412329 | Suppression of IFN-Induced Transcription Underlies IFN Defects Generated by Activated Ras/MEK in Human Cancer Cells |
| Q99594459 | Targeting NF-κB pathway for the therapy of diseases: mechanism and clinical study |
| Q37241502 | Targeting the PIAS1 SUMO ligase pathway to control inflammation |
| Q28247891 | The E3 SUMO ligase PIASy is a regulator of cellular senescence and apoptosis |
| Q28589178 | The PIAS-like protein Zimp10 is essential for embryonic viability and proper vascular development |
| Q28600908 | The language-related transcription factor FOXP2 is post-translationally modified with small ubiquitin-like modifiers |
| Q35214750 | The promyelocytic leukemia protein functions as a negative regulator of IFN-gamma signaling |
| Q36898668 | The role of type I interferons in TLR responses. |
| Q37197979 | Toxoplasma gondii TgIST co-opts host chromatin repressors dampening STAT1-dependent gene regulation and IFN-γ-mediated host defenses. |
| Q34071375 | Unique Type I Interferon Responses Determine the Functional Fate of Migratory Lung Dendritic Cells during Influenza Virus Infection |
| Q36869463 | Virus infection triggers SUMOylation of IRF3 and IRF7, leading to the negative regulation of type I interferon gene expression |
| Q34803388 | Zimp7 and Zimp10, two novel PIAS-like proteins, function as androgen receptor coregulators |
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