From Genes to Ecosystems in Microbiology: Modeling Approaches and the Importance of Individuality

scientific article published on 27 November 2017

From Genes to Ecosystems in Microbiology: Modeling Approaches and the Importance of Individuality is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.3389/FMICB.2017.02299
P932PMC publication ID5711835
P698PubMed publication ID29230200

P50authorJohan H J LeveauQ90257428
Clara PratsQ52731169
Jan-Ulrich KreftQ54143137
P2093author name stringCaroline M Plugge
Weiwen Zhang
Ferdi L Hellweger
P2860cites workDynamic flux balance modeling of microbial co-cultures for efficient batch fermentation of glucose and xylose mixtures.Q54378421
Summer heatwaves promote blooms of harmful cyanobacteriaQ56115994
A problem of persistence: still more questions than answers?Q56761811
Is maximization of molar yield in metabolic networks favoured by evolution?Q57320470
Individual-based modelling of adaptation in marine microbial populations using genetically defined physiological parametersQ57933910
The GS-GOGAT pathway is not operative in the heterocysts. Cloning and expression of glsF gene from the cyanobacterium Anabaena sp. PCC 7120Q58480360
Penetration of oxygen into bacterial coloniesQ70445543
Micromixing in fermentors: metabolic changes in Saccharomyces cerevisiae and their relationship to fluid turbulenceQ81570454
Embracing the mantra of modellers and synthesizing omics, experiments and modelsQ88616813
Localization of protein aggregation in Escherichia coli is governed by diffusion and nucleoid macromolecular crowding effectQ21563476
Environments that induce synthetic microbial ecosystemsQ21563487
Robust growth of Escherichia coliQ24611036
A whole-cell computational model predicts phenotype from genotypeQ24622101
Non-genetic heterogeneity from stochastic partitioning at cell divisionQ24631799
Comprehensive identification of cell cycle-regulated genes of the yeast Saccharomyces cerevisiae by microarray hybridizationQ24657378
Metabolic Network Modeling of Microbial Interactions in Natural and Engineered Environmental SystemsQ26744686
Synthetic Ecology of Microbes: Mathematical Models and ApplicationsQ26777567
Application of metagenomics in the human gut microbiomeQ26851464
Bet hedging in yeast by heterogeneous, age-correlated expression of a stress protectantQ27319462
Analysis of optimality in natural and perturbed metabolic networksQ28213254
Microbial cell individuality and the underlying sources of heterogeneityQ28252446
Comparison of network-based pathway analysis methodsQ28274818
Context-specific metabolic networks are consistent with experimentsQ28472711
Competitive and cooperative metabolic interactions in bacterial communities.Q39676882
Stoichiometric flux balance models quantitatively predict growth and metabolic by-product secretion in wild-type Escherichia coli W3110.Q39916365
Flux balance analysis accounting for metabolite dilutionQ41018622
Use of agent-based modeling to explore the mechanisms of intracellular phosphorus heterogeneity in cultured phytoplanktonQ41436525
Stoichiometric model and flux balance analysis for a mixed culture of Leptospirillum ferriphilum and Ferroplasma acidiphilum.Q41693997
Dynamic metabolic modeling of a microaerobic yeast co-culture: predicting and optimizing ethanol production from glucose/xylose mixturesQ42012504
Isolated microbial single cells and resulting micropopulations grow faster in controlled environmentsQ42259015
Emergent cooperation in microbial metabolismQ42397954
Genome-scale dynamic modeling of the competition between Rhodoferax and Geobacter in anoxic subsurface environmentsQ42743118
Genome‐scale metabolic modeling of a clostridial co‐culture for consolidated bioprocessingQ42954180
N-terminal acetylation and replicative age affect proteasome localization and cell fitness during agingQ43088198
Metabolic modelling of syntrophic-like growth of a 1,3-propanediol producer, Clostridium butyricum, and a methanogenic archeon, Methanosarcina mazei, under anaerobic conditionsQ43292159
High and stable substrate specificities of microorganisms in enhanced biological phosphorus removal plantsQ43353837
Characterization and modelling of interspecies electron transfer mechanisms and microbial community dynamics of a syntrophic associationQ44156854
Carrying photosynthesis genes increases ecological fitness of cyanophage in silicoQ44364538
Quality control: putting protein aggregates in a bindQ45828012
Self-destructive cooperation mediated by phenotypic noise.Q45951262
How microbes survive in the open ocean.Q46004142
Asymmetric Damage Segregation Constitutes an Emergent Population-Level Stress ResponseQ46273057
A road map for the development of community systems (CoSy) biologyQ46534952
Dynamic, mechanistic, molecular-level modelling of cyanobacteria: Anabaena and nitrogen interactionQ46566955
Escherichia coliadapts to tetracycline resistance plasmid (pBR322) by mutating endogenous potassium transport:in silicohypothesis testingQ46637874
The design of long‐term effective uranium bioremediation strategy using a community metabolic modelQ47891637
The mechanics of bacterial cluster formation on plant leaf surfaces as revealed by bioreporter technologyQ50501831
Microbial seed banks: the ecological and evolutionary implications of dormancyQ51173560
Trade-offs of chemotactic foraging in turbulent waterQ51304105
Phenotypic diversity, population growth, and information in fluctuating environmentsQ51965535
From molecular noise to behavioural variability in a single bacteriumQ52000300
Stochasticity of metabolism and growth at the single-cell levelQ53053028
100 Years since Streeter and Phelps: It Is Time To Update the Biology in Our Water Quality ModelsQ53229729
Community flux balance analysis for microbial consortia at balanced growthQ28533513
Plankton networks driving carbon export in the oligotrophic oceanQ28603507
A genome-wide analysis of promoter-mediated phenotypic noise in Escherichia coliQ28732701
Ecosystem dynamics based on plankton functional types for global ocean biogeochemistry modelsQ29031510
Bacterial community variation in human body habitats across space and timeQ29547432
Reconstruction of biochemical networks in microorganismsQ29616018
Bacterial persistence as a phenotypic switchQ29618111
Treg induction by a rationally selected mixture of Clostridia strains from the human microbiotaQ29618128
Metabolic network modeling of microbial communitiesQ30279122
Predicting the response of the deep-ocean microbiome to geochemical perturbations by hydrothermal vents.Q30377666
Novel multiscale modeling tool applied to Pseudomonas aeruginosa biofilm formationQ30416783
Asymmetric segregation of protein aggregates is associated with cellular aging and rejuvenation.Q30481495
Modelling emergence of oscillations in communicating bacteria: a structured approach from one to many cellsQ30534748
Microbial community structure in autotrophic nitrifying granules characterized by experimental and simulation analysesQ30874473
Context-specific metabolic network reconstruction of a naphthalene-degrading bacterial community guided by metaproteomic dataQ30885879
Compartmentalized function through cell differentiation in filamentous cyanobacteria.Q30960272
Biofilms promote altruismQ31104215
In silico approaches to study mass and energy flows in microbial consortia: a syntrophic case study.Q33517877
Antimalarial drug targets in Plasmodium falciparum predicted by stage-specific metabolic network analysisQ33679330
A modular minimal cell model: purine and pyrimidine transport and metabolismQ33696631
Controlling harmful cyanobacterial blooms in a world experiencing anthropogenic and climatic-induced changeQ33827687
Genome complexity, robustness and genetic interactions in digital organisms.Q33871822
Metabolic resource allocation in individual microbes determines ecosystem interactions and spatial dynamicsQ33900751
A computational exploration of bacterial metabolic diversity identifying metabolic interactions and growth-efficient strain communitiesQ34050854
OptCom: a multi-level optimization framework for the metabolic modeling and analysis of microbial communitiesQ34154442
Dynamic flux balance analysis of diauxic growth in Escherichia coliQ34178626
Ecosystems biology of microbial metabolismQ34185936
Insight into human alveolar macrophage and M. tuberculosis interactions via metabolic reconstructionsQ34344292
Fission yeast does not age under favorable conditions, but does so after stress.Q34371090
Adaptability of non-genetic diversity in bacterial chemotaxisQ34411302
Analysis of surface protein expression reveals the growth pattern of the gram-negative outer membraneQ34426332
Marine microbes see a sea of gradientsQ34464187
Diel gene expression profiles of a phosphorus limited mountain lake using metatranscriptomics.Q34487097
Scaling laws governing stochastic growth and division of single bacterial cellsQ34526498
Architecture of a transcribing-translating expressomeQ34555220
Cyanobacterial daily life with Kai-based circadian and diurnal genome-wide transcriptional control in Synechococcus elongatusQ37310804
Asymmetrical distribution of the second messenger c-di-GMP upon bacterial cell divisionQ37531699
Gene-centric approach to integrating environmental genomics and biogeochemical models.Q37571168
Compartmentalized cyanophycin metabolism in the diazotrophic filaments of a heterocyst-forming cyanobacteriumQ37640993
Phase variation: how to create and coordinate population diversity.Q37835537
Microbial modulators of soil carbon storage: integrating genomic and metabolic knowledge for global prediction.Q38153966
How sisters grow apart: mycobacterial growth and divisionQ38226730
Global analysis of the genetic network controlling a bacterial cell cycleQ38305782
Non-random distribution of macromolecules as driving forces for phenotypic variation.Q38479855
Quantification of lateral heterogeneity in carbohydrate permeability of isolated plant leaf cuticles.Q38834875
Constraint-based stoichiometric modelling from single organisms to microbial communities.Q39196318
Inoculation density and nutrient level determine the formation of mushroom-shaped structures in Pseudomonas aeruginosa biofilms.Q39406850
Distribution of bacterial growth activity in flow-chamber biofilmsQ39527850
Metabolic potential of microbial mats and microbialites: Autotrophic capabilities described by an in silico stoichiometric approach from shared genomic resources.Q39669162
Repair rather than segregation of damage is the optimal unicellular aging strategyQ34568460
Single-cell analysis reveals gene-expression heterogeneity in syntrophic dual-culture of Desulfovibrio vulgaris with Methanosarcina barkeriQ34698812
Metabolic modeling of species interaction in the human microbiome elucidates community-level assembly rulesQ34822704
Understanding the interactions between bacteria in the human gut through metabolic modelingQ34975280
Explaining bacterial dispersion on leaf surfaces with an individual-based model (PHYLLOSIM)Q35016784
Ecological modeling from time-series inference: insight into dynamics and stability of intestinal microbiotaQ35069150
Age-correlated stress resistance improves fitness of yeast: support from agent-based simulationsQ35094615
Genome-scale metabolic reconstructions of Bifidobacterium adolescentis L2-32 and Faecalibacterium prausnitzii A2-165 and their interactionQ35141420
d-OptCom: Dynamic multi-level and multi-objective metabolic modeling of microbial communitiesQ35151234
Precision microbiome reconstitution restores bile acid mediated resistance to Clostridium difficile.Q35163017
Metabolic model reconstruction and analysis of an artificial microbial ecosystem for vitamin C production.Q35166250
Emergent biosynthetic capacity in simple microbial communitiesQ35200847
Quantifying the effects of the division of labor in metabolic pathwaysQ35209137
Spatially-resolved metabolic cooperativity within dense bacterial coloniesQ35223683
Modelling the emergent dynamics and major metabolites of the human colonic microbiotaQ35228982
Anoxic Conditions Promote Species-Specific Mutualism between Gut Microbes In SilicoQ35595024
Unraveling interactions in microbial communities - from co-cultures to microbiomes.Q35620876
Metabolic dependencies drive species co-occurrence in diverse microbial communitiesQ35622200
Metabolic modeling of a mutualistic microbial community.Q35742362
Calibration and analysis of genome-based models for microbial ecologyQ35810400
MDSINE: Microbial Dynamical Systems INference Engine for microbiome time-series analyses.Q36040381
Advancing microbial sciences by individual-based modellingQ36041733
Asymmetry and aging of mycobacterial cells lead to variable growth and antibiotic susceptibilityQ36096651
Cell-to-cell heterogeneity in growth rate and gene expression in Methylobacterium extorquens AM1Q36098414
Integrating biogeochemistry with multiomic sequence information in a model oxygen minimum zoneQ36140307
Modelling plankton ecosystems in the meta-omics era. Are we ready?Q36304875
Relationship between cellular response and behavioral variability in bacterial chemotaxisQ36491299
Evidence for hydrogen oxidation and metabolic plasticity in widespread deep-sea sulfur-oxidizing bacteriaQ36512366
In situ substrate preferences of abundant bacterioplankton populations in a prealpine freshwater lake.Q36792485
Heterogeneity in protein expression induces metabolic variability in a modeled Escherichia coli population.Q37117908
Bistability, epigenetics, and bet-hedging in bacteriaQ37184651
Superposition of Individual Activities: Urea-Mediated Suppression of Nitrate Uptake in the Dinoflagellate Prorocentrum minimum Revealed at the Population and Single-Cell Levels.Q37201851
Coupling a genome-scale metabolic model with a reactive transport model to describe in situ uranium bioremediation.Q37274785
Transcriptional Control in Marine Copiotrophic and Oligotrophic Bacteria with Streamlined GenomesQ37287087
P921main subjectecosystemQ37813
P304page(s)2299
P577publication date2017-11-27
P1433published inFrontiers in MicrobiologyQ27723481
P1476titleFrom Genes to Ecosystems in Microbiology: Modeling Approaches and the Importance of Individuality
P478volume8

Reverse relations

cites work (P2860)
Q64974597Augmenting Biogas Process Modeling by Resolving Intracellular Metabolic Activity.
Q61449817Extreme Osmotolerance and Halotolerance in Food-Relevant Yeasts and the Role of Glycerol-Dependent Cell Individuality
Q58757809FLYCOP: metabolic modeling-based analysis and engineering microbial communities
Q104501886Future directions for studying resilience of the oral ecosystem
Q97526594Toward Engineering Biosystems With Emergent Collective Functions

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