| scholarly article | Q13442814 |
| P2093 | author name string | Alan S Verkman | |
| Lukmanee Tradtrantip | |||
| Puay-Wah Phuan | |||
| Alex J Smith | |||
| Marc O Anderson | |||
| P2860 | cites work | cDNA cloning, gene organization, and chromosomal localization of a human mercurial insensitive water channel. Evidence for distinct transcriptional units | Q24310448 |
| Syntrophin-dependent expression and localization of Aquaporin-4 water channel protein | Q24555081 | ||
| Aquaporin 4 and neuromyelitis optica | Q24613666 | ||
| A paravascular pathway facilitates CSF flow through the brain parenchyma and the clearance of interstitial solutes, including amyloid β. | Q24631193 | ||
| Crystal structure of human aquaporin 4 at 1.8 A and its mechanism of conductance | Q24648744 | ||
| Greatly improved neurological outcome after spinal cord compression injury in AQP4-deficient mice. | Q27863378 | ||
| Identification of arylsulfonamides as Aquaporin 4 inhibitors | Q27919706 | ||
| Impaired hearing in mice lacking aquaporin-4 water channels | Q28585889 | ||
| Determinants of aquaporin-4 assembly in orthogonal arrays revealed by live-cell single-molecule fluorescence imaging | Q30488992 | ||
| Aquaporin-4-dependent K(+) and water transport modeled in brain extracellular space following neuroexcitation | Q30531303 | ||
| Aggregation state determines the localization and function of M1- and M23-aquaporin-4 in astrocytes | Q30572079 | ||
| Delayed onset of brain edema and mislocalization of aquaporin-4 in dystrophin-null transgenic mice | Q30723936 | ||
| Improved long-term outcome after transient cerebral ischemia in aquaporin-4 knockout mice | Q31036924 | ||
| Automated cell-based assay for screening of aquaporin inhibitors. | Q33496547 | ||
| Pretreatment with a novel aquaporin 4 inhibitor, TGN-020, significantly reduces ischemic cerebral edema | Q33711269 | ||
| Inhibition of aquaporin-1 and aquaporin-4 water permeability by a derivative of the loop diuretic bumetanide acting at an internal pore-occluding binding site | Q43106571 | ||
| Involvement of aquaporin-4 in astroglial cell migration and glial scar formation | Q43406920 | ||
| Mildly abnormal retinal function in transgenic mice without Müller cell aquaporin-4 water channels | Q43871295 | ||
| K+ waves in brain cortex visualized using a long-wavelength K+-sensing fluorescent indicator. | Q44390087 | ||
| Increased seizure threshold in mice lacking aquaporin-4 water channels | Q44839011 | ||
| Inhibition of IkappaB phosphorylation in cardiomyocytes attenuates myocardial ischemia/reperfusion injury | Q44934421 | ||
| Accelerated progression of kaolin-induced hydrocephalus in aquaporin-4-deficient mice. | Q45060496 | ||
| Increased seizure duration and slowed potassium kinetics in mice lacking aquaporin-4 water channels. | Q46024174 | ||
| Greatly impaired migration of implanted aquaporin-4-deficient astroglial cells in mouse brain toward a site of injury | Q46072044 | ||
| Protective role of aquaporin-4 water channels after contusion spinal cord injury | Q46486212 | ||
| Impairment of angiogenesis and cell migration by targeted aquaporin-1 gene disruption. | Q46588165 | ||
| Aquaporin-4 facilitates reabsorption of excess fluid in vasogenic brain edema. | Q46651668 | ||
| Localization of MIWC and GLIP water channel homologs in neuromuscular, epithelial and glandular tissues | Q46744705 | ||
| Identification of aquaporin 4 inhibitors using in vitro and in silico methods | Q46817469 | ||
| Inhibition of aquaporin 4 by antiepileptic drugs | Q46820895 | ||
| Aquaporin-4 knockout regulated cocaine-induced behavior and neurochemical changes in mice | Q48488746 | ||
| Absence of orthogonal arrays in kidney, brain and muscle from transgenic knockout mice lacking water channel aquaporin-4. | Q48565812 | ||
| Specialized membrane domains for water transport in glial cells: high-resolution immunogold cytochemistry of aquaporin-4 in rat brain. | Q48823528 | ||
| Quaternary ammonium compounds as water channel blockers. Specificity, potency, and site of action. | Q50114413 | ||
| Aquaporin-4 gene deletion in mice increases focal edema associated with staphylococcal brain abscess. | Q50482942 | ||
| Impact of aquaporin-4 channels on K+ buffering and gap junction coupling in the hippocampus | Q83739626 | ||
| The mercurial insensitive water channel (AQP-4) forms orthogonal arrays in stably transfected Chinese hamster ovary cells | Q95817895 | ||
| Aquaporins: important but elusive drug targets. | Q33792739 | ||
| Heterotetrameric composition of aquaporin-4 water channels. | Q33872001 | ||
| Microfiberoptic measurement of extracellular space volume in brain and tumor slices based on fluorescent dye partitioning | Q34062264 | ||
| Small-molecule inhibitors of NMO-IgG binding to aquaporin-4 reduce astrocyte cytotoxicity in neuromyelitis optica. | Q34154265 | ||
| Critical role of aquaporin-4 (AQP4) in astrocytic Ca2+ signaling events elicited by cerebral edema | Q34490433 | ||
| An aquaporin-4/transient receptor potential vanilloid 4 (AQP4/TRPV4) complex is essential for cell-volume control in astrocytes | Q34572856 | ||
| Proinflammatory role of aquaporin-4 in autoimmune neuroinflammation | Q34813295 | ||
| Binding affinity and specificity of neuromyelitis optica autoantibodies to aquaporin-4 M1/M23 isoforms and orthogonal arrays | Q34963829 | ||
| Neuroprotective effect of aquaporin-4 deficiency in a mouse model of severe global cerebral ischemia produced by transient 4-vessel occlusion. | Q35013123 | ||
| Model of aquaporin-4 supramolecular assembly in orthogonal arrays based on heterotetrameric association of M1-M23 isoforms | Q35070474 | ||
| Anti-aquaporin-4 monoclonal antibody blocker therapy for neuromyelitis optica. | Q35857869 | ||
| Aquaporins in clinical medicine | Q35870411 | ||
| Lack of aquaporin-4 water transport inhibition by antiepileptics and arylsulfonamides | Q35885354 | ||
| Aquaporin-4 Mz isoform: brain expression, supramolecular assembly and neuromyelitis optica antibody binding | Q35892159 | ||
| Experimental Evaluation of Proposed Small-Molecule Inhibitors of Water Channel Aquaporin-1 | Q35963493 | ||
| Mildly Reduced Brain Swelling and Improved Neurological Outcome in Aquaporin-4 Knockout Mice following Controlled Cortical Impact Brain Injury. | Q36108495 | ||
| Superresolution Imaging of Aquaporin-4 Cluster Size in Antibody-Stained Paraffin Brain Sections | Q36426460 | ||
| Super-resolution imaging of aquaporin-4 orthogonal arrays of particles in cell membranes. | Q36451210 | ||
| Aquaporin-4 regulates the velocity and frequency of cortical spreading depression in mice. | Q36552112 | ||
| Molecular cloning of a mercurial-insensitive water channel expressed in selected water-transporting tissues | Q36674076 | ||
| Glial cell aquaporin-4 overexpression in transgenic mice accelerates cytotoxic brain swelling. | Q36678507 | ||
| Impaired olfaction in mice lacking aquaporin-4 water channels. | Q36841776 | ||
| Discovery of the aquaporins and development of the field | Q37354949 | ||
| Spatial model of convective solute transport in brain extracellular space does not support a "glymphatic" mechanism. | Q37457029 | ||
| Live cell analysis of aquaporin-4 m1/m23 interactions and regulated orthogonal array assembly in glial cells | Q37467723 | ||
| Greatly improved survival and neuroprotection in aquaporin-4-knockout mice following global cerebral ischemia | Q37503646 | ||
| Structure and functions of aquaporin-4-based orthogonal arrays of particles | Q37854201 | ||
| Selected cysteine point mutations confer mercurial sensitivity to the mercurial-insensitive water channel MIWC/AQP-4. | Q38362748 | ||
| Three-dimensional organ scanning reveals brain edema reduction in a rat model of stroke treated with an aquaporin 4 inhibitor | Q38775679 | ||
| Challenging AQP4 druggability for NMO-IgG antibody binding using molecular dynamics and molecular interaction fields | Q39021970 | ||
| Evidences for a leaky scanning mechanism for the synthesis of the shorter M23 protein isoform of aquaporin-4: implication in orthogonal array formation and neuromyelitis optica antibody interaction | Q39539421 | ||
| Role of aquaporin-4 in the regulation of migration and invasion of human glioma cells | Q39572770 | ||
| Very high single channel water permeability of aquaporin-4 in baculovirus-infected insect cells and liposomes reconstituted with purified aquaporin-4. | Q41104307 | ||
| Test of the 'glymphatic' hypothesis demonstrates diffusive and aquaporin-4-independent solute transport in rodent brain parenchyma. | Q41578156 | ||
| Aquaporin-4 deletion in mice reduces brain edema after acute water intoxication and ischemic stroke. | Q41717152 | ||
| Impairment of select forms of spatial memory and neurotrophin-dependent synaptic plasticity by deletion of glial aquaporin-4. | Q42487285 | ||
| Evidence against functional interaction between aquaporin-4 water channels and Kir4.1 potassium channels in retinal Müller cells. | Q42621778 | ||
| P433 | issue | 12 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 1161-1170 | |
| P577 | publication date | 2017-11-05 | |
| P1433 | published in | Expert Opinion on Therapeutic Targets | Q5421214 |
| P1476 | title | The aquaporin-4 water channel as a potential drug target in neurological disorders | |
| P478 | volume | 21 |
| Q64087442 | AQP4ex is crucial for the anchoring of AQP4 at the astrocyte end-feet and for neuromyelitis optica antibody binding |
| Q91938747 | Advances in the Potential Biomarkers of Epilepsy |
| Q58105591 | Aloin Inhibits Müller Cells Swelling in a Rat Model of Thioacetamide-Induced Hepatic Retinopathy |
| Q48337589 | Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes-2. |
| Q96162980 | Clearance of activity-evoked K+ transients and associated glia cell swelling occur independently of AQP4: A study with an isoform-selective AQP4 inhibitor |
| Q90517167 | Experimental animal models of aquaporin-4-IgG-seropositive neuromyelitis optica spectrum disorders: progress and shortcomings |
| Q91972929 | Ginsenoside-Rb1 for Ischemic Stroke: A Systematic Review and Meta-analysis of Preclinical Evidence and Possible Mechanisms |
| Q90400196 | Herbal Compatibility of Ginseng and Rhubarb Exerts Synergistic Neuroprotection in Cerebral Ischemia/Reperfusion Injury of Rats |
| Q64103262 | Inhibitors of Mammalian Aquaporin Water Channels |
| Q47216965 | Iridoids and Other Monoterpenes in the Alzheimer's Brain: Recent Development and Future Prospects |
| Q97524144 | Methylene blue ameliorates brain edema in rats with experimental ischemic stroke via inhibiting aquaporin 4 expression |
| Q58777731 | Profile of intravenous glyburide for the prevention of cerebral edema following large hemispheric infarction: evidence to date |
| Q89944662 | Regulation of AQP4 in the Central Nervous System |
| Q64118530 | Role of Glutamatergic Excitotoxicity in Neuromyelitis Optica Spectrum Disorders |
| Q58743091 | SMMDB: a web-accessible database for small molecule modulators and their targets involved in neurological diseases |
| Q89719343 | The Pattern of AQP4 Expression in the Ageing Human Brain and in Cerebral Amyloid Angiopathy |
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