Graded sympatholytic effect of exogenous ATP on postjunctional alpha-adrenergic vasoconstriction in the human forearm: implications for vascular control in contracting muscle

scientific article published on 10 July 2008

Graded sympatholytic effect of exogenous ATP on postjunctional alpha-adrenergic vasoconstriction in the human forearm: implications for vascular control in contracting muscle is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1113/JPHYSIOL.2008.154252
P932PMC publication ID2652174
P698PubMed publication ID18617568
P5875ResearchGate publication ID5230982

P2093author name stringBrett S Kirby
Frank A Dinenno
Rick E Carlson
Wyatt F Voyles
P2860cites workInhibition of alpha-adrenergic vasoconstriction in exercising human thigh musclesQ31034272
Exercise attenuates alpha-adrenergic-receptor responsiveness in skeletal muscle vasculatureQ31776933
Exogenous NO administration and alpha-adrenergic vasoconstriction in human limbsQ33188181
The red blood cell as an oxygen sensor: what is the evidence?Q33888508
ATP-induced vasodilation in human skeletal muscleQ35046189
Red blood cell-derived ATP as a regulator of skeletal muscle perfusionQ35621214
Systemic hypoxia and vasoconstrictor responsiveness in exercising human muscleQ36016319
ATP-sensitive potassium channels mediate contraction-induced attenuation of sympathetic vasoconstriction in rat skeletal muscle.Q37367976
Overflow of catecholamine neurotransmitters to the circulation: source, fate, and functionsQ37601429
Neural control of muscle blood flow: importance during dynamic exerciseQ41389735
Skeletal muscle blood flow in humans and its regulation during exerciseQ41760252
Role of erythrocyte in regulating local O2 delivery mediated by hemoglobin oxygenationQ43610552
Is sympathetic neural vasoconstriction blunted in the vascular bed of exercising human muscle?Q44013303
Attenuated vascular responsiveness to noradrenaline release during dynamic exercise in dogsQ44013306
Aging and forearm postjunctional alpha-adrenergic vasoconstriction in healthy men.Q44131319
Erythrocyte and the regulation of human skeletal muscle blood flow and oxygen delivery: role of circulating ATP.Q44232562
alpha1- and alpha2-adrenergic vasoconstriction is blunted in contracting human muscleQ44317055
Blunted sympathetic vasoconstriction in contracting skeletal muscle of healthy humans: is nitric oxide obligatory?Q44569252
Circulating ATP-induced vasodilatation overrides sympathetic vasoconstrictor activity in human skeletal muscleQ44904872
Combined NO and PG inhibition augments alpha-adrenergic vasoconstriction in contracting human skeletal muscleQ44991344
Inhibition of KATP channel activity augments baroreflex-mediated vasoconstriction in exercising human skeletal muscleQ45042747
Impaired modulation of sympathetic alpha-adrenergic vasoconstriction in contracting forearm muscle of ageing men.Q46537525
During hypoxic exercise some vasoconstriction is needed to match O2 delivery with O2 demand at the microcirculatory levelQ46954388
Nitric oxide-dependent modulation of sympathetic neural control of oxygenation in exercising human skeletal muscle.Q49148880
Interaction between sympathetic nerve activation and muscle fibre contraction in resistance vessels of hamster retractor muscle.Q51837145
Microvascular response to blockade of prostaglandin synthesis in rat skeletal muscle.Q51860523
Deformation-induced ATP release from red blood cells requires CFTR activity.Q54117015
Characterization of ATP-induced vasodilation in the human forearm vascular bed.Q54193800
Resistance or conductance for expression of arterial vascular tone.Q54358451
Maximal muscular vascular conductances during whole body upright exercise in humansQ58818190
Release of ATP from human erythrocytes in response to a brief period of hypoxia and hypercapniaQ67503213
Interactions between alpha-adrenoceptors and adenosine receptors on microvascular smooth muscleQ67916564
Regional vascular resistance vs. conductance: which index for baroreflex responses?Q68201043
Differential sensitivity of arteriolar alpha 1- and alpha 2-adrenoceptor constriction to metabolic inhibition during rat skeletal muscle contractionQ68241246
A dual function for adenosine 5'-triphosphate in the regulation of vascular tone. Excitatory cotransmitter with noradrenaline from perivascular nerves and locally released inhibitory intravascular agentQ70142019
The erythrocyte as a regulator of vascular toneQ70986072
Inhibition of alpha 2-adrenergic vasoconstriction during contraction of glycolytic, not oxidative, rat hindlimb muscleQ72675196
Gender differences in sensitivity to adrenergic agonists of forearm resistance vasculatureQ73069737
Having it both ways? Vasoconstriction in contracting musclesQ73459148
Effect of sympathoinhibition on exercise performance in patients with heart failureQ73542981
Metabolic modulation of sympathetic vasoconstriction in human skeletal muscle: role of tissue hypoxiaQ74257999
Nitric oxide mediates contraction-induced attenuation of sympathetic vasoconstriction in rat skeletal muscleQ74315971
Blood pressure during supine exercise in idiopathic orthostatic hypotensionQ79068596
Functional sympatholysis during muscular activity. Observations on influence of carotid sinus on oxygen uptakeQ79635280
Effects of ATP-induced leg vasodilation on VO2 peak and leg O2 extraction during maximal exercise in humansQ80128662
Ageing and leg postjunctional alpha-adrenergic vasoconstrictor responsiveness in healthy menQ80226402
Mechanical effects of muscle contraction do not blunt sympathetic vasoconstriction in humansQ81795827
P433issue17
P407language of work or nameEnglishQ1860
P921main subjectvasoconstrictionQ1067506
P304page(s)4305-4316
P577publication date2008-07-10
P1433published inJournal of PhysiologyQ7743612
P1476titleGraded sympatholytic effect of exogenous ATP on postjunctional alpha-adrenergic vasoconstriction in the human forearm: implications for vascular control in contracting muscle
P478volume586

Reverse relations

cites work (P2860)
Q38019919ATP as a mediator of erythrocyte-dependent regulation of skeletal muscle blood flow and oxygen delivery in humans
Q37668494ATP metabolism in skeletal muscle arterioles.
Q46178223ATP-induced vasodilation and purinergic receptors in the human leg: roles of nitric oxide, prostaglandins, and adenosine
Q84552796ATP-mediated vasodilatation occurs via activation of inwardly rectifying potassium channels in humans
Q46395479ATP: a double-edged signalling molecule regulating the flow of oxygen
Q44585114Activation of ATP/UTP-selective receptors increases blood flow and blunts sympathetic vasoconstriction in human skeletal muscle
Q23919099Acute dilation to alpha(2)-adrenoceptor antagonists uncovers dual constriction and dilation mediated by arterial alpha(2)- adrenoceptors
Q37391915Adenosine receptor antagonist and augmented vasodilation during hypoxic exercise
Q34304875Adrenergic receptor activation involves ATP release and feedback through purinergic receptors
Q84226900Augmented skeletal muscle hyperaemia during hypoxic exercise in humans is blunted by combined inhibition of nitric oxide and vasodilating prostaglandins
Q37308947Blood temperature and perfusion to exercising and non-exercising human limbs.
Q38693262Cardiovascular Adaptations to Exercise Training
Q51717573Chronic hypoxia increases arterial blood pressure and reduces adenosine and ATP induced vasodilatation in skeletal muscle in healthy humans.
Q87153080Contracting human skeletal muscle maintains the ability to blunt α1 -adrenergic vasoconstriction during KIR channel and Na(+) /K(+) -ATPase inhibition
Q37203118Differential effects of nebivolol versus metoprolol on functional sympatholysis in hypertensive humans
Q34447030Disparity in regional and systemic circulatory capacities: do they affect the regulation of the circulation?
Q47176957Effects of Dăoyĭn Qìgōng in postpolio syndrome patients with cold intolerance
Q88554643Elevated extracellular potassium prior to muscle contraction reduces onset and steady-state exercise hyperemia in humans
Q46078227Endothelium-dependent vasodilatation and exercise hyperaemia in ageing humans: impact of acute ascorbic acid administration
Q51550205Endothelium-dependent vasodilatory signalling modulates α1 -adrenergic vasoconstriction in contracting skeletal muscle of humans.
Q34426194Erythrocyte-dependent regulation of human skeletal muscle blood flow: role of varied oxyhemoglobin and exercise on nitrite, S-nitrosohemoglobin, and ATP.
Q35043742Functional sympatholysis during exercise in patients with type 2 diabetes with intact response to acetylcholine
Q85838301Haemodynamic responses to dehydration in the resting and exercising human leg
Q34720069Hemodynamic responses to heat stress in the resting and exercising human leg: insight into the effect of temperature on skeletal muscle blood flow
Q88511928Impaired modulation of postjunctional α1 - but not α2 -adrenergic vasoconstriction in contracting forearm muscle of postmenopausal women
Q36086617Impaired skeletal muscle blood flow control with advancing age in humans: attenuated ATP release and local vasodilation during erythrocyte deoxygenation
Q47651108Integration of Central and Peripheral Regulation of the Circulation during Exercise: Acute and Chronic Adaptations
Q30979635Intradermal administration of ATP does not mitigate tyramine-stimulated vasoconstriction in human skin.
Q34296753KIR channel activation contributes to onset and steady-state exercise hyperemia in humans
Q84959282Lifelong physical activity preserves functional sympatholysis and purinergic signalling in the ageing human leg
Q42348099Local temperature-sensitive mechanisms are important mediators of limb tissue hyperemia in the heat-stressed human at rest and during small muscle mass exercise
Q43143590Losing control over adenosine 5'-triphosphate release: implications for the red blood cell storage lesion
Q36787416Mechanical effects of muscle contraction increase intravascular ATP draining quiescent and active skeletal muscle in humans
Q35395499Mechanisms of ATP-mediated vasodilation in humans: modest role for nitric oxide and vasodilating prostaglandins
Q37054924Mechanisms of rapid vasodilation after a brief contraction in human skeletal muscle
Q83842055Modulation of postjunctional α-adrenergic vasoconstriction during exercise and exogenous ATP infusions in ageing humans
Q43268360Muscle interstitial ATP and norepinephrine concentrations in the human leg during exercise and ATP infusion
Q34173595Neural control of blood flow during exercise in human metabolic syndrome
Q34753720Nitric oxide-mediated vasodilation becomes independent of beta-adrenergic receptor activation with increased intensity of hypoxic exercise
Q84102624Not a fine wine: the ATP hypothesis may not get better with age
Q41840262Persistence of functional sympatholysis post-exercise in human skeletal muscle
Q58577734Plasma Nucleotide Dynamics during Exercise and Recovery in Highly Trained Athletes and Recreationally Active Individuals
Q42089069Prolonged adenosine triphosphate infusion and exercise hyperemia in humans
Q39295378Purinergic control of red blood cell metabolism: novel strategies to improve red cell storage quality
Q38533603Reduced blood flow to contracting skeletal muscle in ageing humans: is it all an effect of sand through the hourglass?
Q52146628Reflex control of the circulation during exercise.
Q27001180Regulation of increased blood flow (hyperemia) to muscles during exercise: a hierarchy of competing physiological needs
Q38579190Regulation of skeletal muscle blood flow during exercise in ageing humans
Q33390289Role of {alpha}1-adrenergic vasoconstriction in the regulation of skeletal muscle blood flow with advancing age.
Q33466664Skeletal muscle blood flow responses to hypoperfusion at rest and during rhythmic exercise in humans
Q36788024Sources of intravascular ATP during exercise in humans: critical role for skeletal muscle perfusion
Q48314410Sympatholytic effect of intravascular ATP is independent of nitric oxide, prostaglandins, Na+ /K+ -ATPase and KIR channels in humans
Q41860416Temperature-dependent release of ATP from human erythrocytes: mechanism for the control of local tissue perfusion
Q50426563The effect of purinergic P2 receptor blockade on skeletal muscle exercise hyperemia in miniature swine
Q46317272Tripartite function of ATP in vascular signalling
Q36124885Vascular regulation via KIR channels and Na(+)/K(+)-ATPase
Q42921063Vasodilatory responsiveness to adenosine triphosphate in ageing humans
Q34305319α-Adrenergic control of blood flow during exercise: effect of sex and menstrual phase

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