scholarly article | Q13442814 |
P356 | DOI | 10.1007/S00359-010-0582-9 |
P698 | PubMed publication ID | 20820785 |
P50 | author | David K. Jones | Q56440773 |
Christopher A Ahern | Q57070092 | ||
P2093 | author name string | Maen F Sarhan | |
Peter C Ruben | |||
Chong Hyun Lee | |||
P2860 | cites work | KcsA crystal structure as framework for a molecular model of the Na(+) channel pore | Q73977454 |
A defect in skeletal muscle sodium channel deactivation exacerbates hyperexcitability in human paramyotonia congenita | Q74315934 | ||
Selectivity filter residues contribute unequally to pore stabilization in voltage-gated sodium channels | Q81360756 | ||
Mechanisms of Adaptation in a Predator-Prey Arms Race: TTX-Resistant Sodium Channels | Q22065829 | ||
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences | Q24336098 | ||
Primary structure and functional expression of the human cardiac tetrodotoxin-insensitive voltage-dependent sodium channel | Q24563388 | ||
Sequence and genomic structure of the human adult skeletal muscle sodium channel alpha subunit gene on 17q | Q28208755 | ||
Evolutionary diversification of TTX-resistant sodium channels in a predator-prey interaction | Q28243909 | ||
International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels | Q28289125 | ||
A single residue differentiates between human cardiac and skeletal muscle Na+ channel slow inactivation | Q28363700 | ||
A novel persistent tetrodotoxin-resistant sodium current in SNS-null and wild-type small primary sensory neurons | Q28377530 | ||
Toxin-resistant sodium channels: parallel adaptive evolution across a complete gene family | Q30436012 | ||
Ultra-slow inactivation in mu1 Na+ channels is produced by a structural rearrangement of the outer vestibule | Q30447518 | ||
Binding properties of (3)H-PbTx-3 and (3)H-saxitoxin to brain membranes and to skeletal muscle membranes of puffer fish Fugu pardalis and the primary structure of a voltage-gated Na(+) channel alpha-subunit (fMNa1) from skeletal muscle of F. pardali | Q30830873 | ||
Structure of the sodium channel pore revealed by serial cysteine mutagenesis. | Q33618326 | ||
Molecular dynamics of the sodium channel pore vary with gating: interactions between P-segment motions and inactivation. | Q33852460 | ||
Molecular motions within the pore of voltage-dependent sodium channels | Q33907113 | ||
Defective fast inactivation recovery and deactivation account for sodium channel myotonia in the I1160V mutant | Q33907568 | ||
Mechanisms of sodium/calcium selectivity in sodium channels probed by cysteine mutagenesis and sulfhydryl modification | Q33915656 | ||
Slow inactivation differs among mutant Na channels associated with myotonia and periodic paralysis | Q33915721 | ||
Voltage-gated sodium channels as therapeutic targets | Q33925684 | ||
Interaction between fast and slow inactivation in Skm1 sodium channels | Q34041249 | ||
On the structural basis for ionic selectivity among Na+, K+, and Ca2+ in the voltage-gated sodium channel | Q34041257 | ||
Steady-state availability of sodium channels. Interactions between activation and slow inactivation | Q34088636 | ||
Holding potential affects the apparent voltage-sensitivity of sodium channel activation in crayfish giant axons | Q34126640 | ||
A mutation in the pore of the sodium channel alters gating | Q34129377 | ||
Differences in saxitoxin and tetrodotoxin binding revealed by mutagenesis of the Na+ channel outer vestibule. | Q34169482 | ||
Rapid and slow voltage-dependent conformational changes in segment IVS6 of voltage-gated Na(+) channels | Q34173224 | ||
Interactions of the C-11 hydroxyl of tetrodotoxin with the sodium channel outer vestibule | Q34180126 | ||
The cooperative voltage sensor motion that gates a potassium channel | Q34482244 | ||
Na channel inactivation from open and closed states | Q35215140 | ||
The permeability of the sodium channel to metal cations in myelinated nerve | Q36387879 | ||
Coupling interactions between voltage sensors of the sodium channel as revealed by site-specific measurements | Q36412534 | ||
Altered ionic selectivity of the sodium channel revealed by cysteine mutations within the pore | Q36416088 | ||
A structural rearrangement in the sodium channel pore linked to slow inactivation and use dependence | Q36436280 | ||
Tracking voltage-dependent conformational changes in skeletal muscle sodium channel during activation. | Q36436547 | ||
Role of domain 4 in sodium channel slow inactivation | Q36442905 | ||
Immobilizing the moving parts of voltage-gated ion channels | Q36444725 | ||
How membrane proteins sense voltage | Q37114573 | ||
The external pore loop interacts with S6 and S3-S4 linker in domain 4 to assume an essential role in gating control and anticonvulsant action in the Na(+) channel | Q37280509 | ||
Genetic basis of tetrodotoxin resistance in pufferfishes | Q38318555 | ||
Two critical residues in p-loop regions of puffer fish Na+ channels on TTX sensitivity | Q40037690 | ||
Restoration of inactivation and block of open sodium channels by an inactivation gate peptide | Q41469205 | ||
Functional expression and properties of the human skeletal muscle sodium channel | Q41470649 | ||
Voltage sensors in domains III and IV, but not I and II, are immobilized by Na+ channel fast inactivation | Q41608443 | ||
The permeability of the sodium channel to organic cations in myelinated nerve | Q41920397 | ||
The selectivity filter of the voltage-gated sodium channel is involved in channel activation | Q43624026 | ||
17 Cut-open oocyte voltage-clamp technique | Q46504085 | ||
SELECTION ON LOCOMOTOR PERFORMANCE CAPACITY IN A NATURAL POPULATION OF GARTER SNAKES. | Q46717622 | ||
A mutant of TTX-resistant cardiac sodium channels with TTX-sensitive properties | Q48479782 | ||
A cation-pi interaction discriminates among sodium channels that are either sensitive or resistant to tetrodotoxin block. | Q48628517 | ||
Predominant interactions between mu-conotoxin Arg-13 and the skeletal muscle Na+ channel localized by mutant cycle analysis | Q48942641 | ||
Control of ion flux and selectivity by negatively charged residues in the outer mouth of rat sodium channels. | Q49019522 | ||
A conserved ring of charge in mammalian Na+ channels: a molecular regulator of the outer pore conformation during slow inactivation | Q50646634 | ||
Mapping the site of block by tetrodotoxin and saxitoxin of sodium channel II. | Q50796508 | ||
TTX Resistivity of Na+Channel in Newt Retinal Neuron | Q51533333 | ||
A single point mutation confers tetrodotoxin and saxitoxin insensitivity on the sodium channel II. | Q51744647 | ||
COSTS OF EXPLOITING POISONOUS PREY: EVOLUTIONARY TRADE-OFFS IN A PREDATOR-PREY ARMS RACE. | Q54101292 | ||
P433 | issue | 1 | |
P921 | main subject | common garter snake | Q911786 |
P304 | page(s) | 33-43 | |
P577 | publication date | 2010-09-07 | |
P1433 | published in | Journal of Comparative Physiology | Q1709835 |
P1476 | title | Biophysical costs associated with tetrodotoxin resistance in the sodium channel pore of the garter snake, Thamnophis sirtalis | |
P478 | volume | 197 |
Q37735702 | Behavioral and chemical ecology of marine organisms with respect to tetrodotoxin |
Q30424913 | Constraint shapes convergence in tetrodotoxin-resistant sodium channels of snakes |
Q35897348 | Convergent Substitutions in a Sodium Channel Suggest Multiple Origins of Toxin Resistance in Poison Frogs. |
Q30252741 | Convergent adaptation to dangerous prey proceeds through the same first-step mutation in the garter snake Thamnophis sirtalis |
Q57138021 | Large-effect mutations generate trade-off between predatory and locomotor ability during arms race coevolution with deadly prey |
Q30409940 | Parallel evolution of tetrodotoxin resistance in three voltage-gated sodium channel genes in the garter snake Thamnophis sirtalis |
Q24633753 | The chemical and evolutionary ecology of tetrodotoxin (TTX) toxicity in terrestrial vertebrates |
Q34034876 | The molecular mystique of tetrodotoxin |
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