scholarly article | Q13442814 |
P356 | DOI | 10.1074/JBC.M507622200 |
P698 | PubMed publication ID | 16371368 |
P2093 | author name string | Jing Chen | |
Cheng-Kui Qu | |||
Wen-Mei Yu | |||
Kevin D Bunting | |||
Hanako Daino | |||
P2860 | cites work | Mutations in PTPN11, encoding the protein tyrosine phosphatase SHP-2, cause Noonan syndrome | Q24291893 |
Spatial constraints on the recognition of phosphoproteins by the tandem SH2 domains of the phosphatase SH-PTP2 | Q24314461 | ||
Jak2 deficiency defines an essential developmental checkpoint in definitive hematopoiesis | Q24316448 | ||
Crystal structure of the tyrosine phosphatase SHP-2 | Q27748898 | ||
Shc associates with the IL-3 receptor β subunit, SHIP and Gab2 following IL-3 stimulation | Q28137857 | ||
The 'Shp'ing news: SH2 domain-containing tyrosine phosphatases in cell signaling | Q28182148 | ||
Jak2 is essential for signaling through a variety of cytokine receptors | Q28270987 | ||
Activating mutations of the noonan syndrome-associated SHP2/PTPN11 gene in human solid tumors and adult acute myelogenous leukemia | Q28298677 | ||
Nf1 and Gmcsf interact in myeloid leukemogenesis | Q28507018 | ||
Mouse model of Noonan syndrome reveals cell type- and gene dosage-dependent effects of Ptpn11 mutation | Q28594140 | ||
New role for Shc in activation of the phosphatidylinositol 3-kinase/Akt pathway | Q28608965 | ||
Evidence for a physical association between the Shc-PTB domain and the beta c chain of the granulocyte-macrophage colony-stimulating factor receptor | Q28609037 | ||
Dynamic changes of BRCA1 subnuclear location and phosphorylation state are initiated by DNA damage | Q29619360 | ||
Requirement of Shp-2 tyrosine phosphatase in lymphoid and hematopoietic cell development | Q31835063 | ||
Signaling domains of the beta c chain of the GM-CSF/IL-3/IL-5 receptor | Q33661908 | ||
Biased suppression of hematopoiesis and multiple developmental defects in chimeric mice containing Shp-2 mutant cells | Q33781066 | ||
IL-3 signaling and the role of Src kinases, JAKs and STATs: a covert liaison unveiled | Q33941375 | ||
Combinatorial control of the specificity of protein tyrosine phosphatases | Q34180660 | ||
Role of the SHP-2 tyrosine phosphatase in cytokine-induced signaling and cellular response | Q34991820 | ||
Human somatic PTPN11 mutations induce hematopoietic-cell hypersensitivity to granulocyte-macrophage colony-stimulating factor | Q35847470 | ||
Functional analysis of leukemia-associated PTPN11 mutations in primary hematopoietic cells | Q35847802 | ||
Dynamic regulation of the Ras pathway via proteolysis of the NF1 tumor suppressor | Q35964121 | ||
Nf1 regulates hematopoietic progenitor cell growth and ras signaling in response to multiple cytokines | Q36400929 | ||
A deletion mutation in the SH2-N domain of Shp-2 severely suppresses hematopoietic cell development | Q36572223 | ||
Catalytic-dependent and -independent roles of SHP-2 tyrosine phosphatase in interleukin-3 signaling | Q40637759 | ||
Juvenile myelomonocytic leukemia: molecular understanding and prospects for therapy | Q40921921 | ||
Revealing mechanisms for SH2 domain mediated regulation of the protein tyrosine phosphatase SHP-2. | Q41743522 | ||
Somatic mutations in PTPN11 in juvenile myelomonocytic leukemia, myelodysplastic syndromes and acute myeloid leukemia | Q44419404 | ||
Mutations in PTPN11 implicate the SHP-2 phosphatase in leukemogenesis | Q44673842 | ||
Prognostic, therapeutic, and mechanistic implications of a mouse model of leukemia evoked by Shp2 (PTPN11) mutations. | Q44760563 | ||
A negative role of SHP-2 tyrosine phosphatase in growth factor-dependent hematopoietic cell survival | Q44872938 | ||
P433 | issue | 9 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | leukemia | Q29496 |
P304 | page(s) | 5426-5434 | |
P577 | publication date | 2005-12-21 | |
P1433 | published in | Journal of Biological Chemistry | Q867727 |
P1476 | title | Effects of a leukemia-associated gain-of-function mutation of SHP-2 phosphatase on interleukin-3 signaling | |
P478 | volume | 281 |