Oligosaccharide G19 inhibits U-87 MG human glioma cells growth in vitro and in vivo by targeting epidermal growth factor (EGF) and activating p53/p21 signaling

scientific article published on 5 May 2014

Oligosaccharide G19 inhibits U-87 MG human glioma cells growth in vitro and in vivo by targeting epidermal growth factor (EGF) and activating p53/p21 signaling is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1093/GLYCOB/CWU038
P698PubMed publication ID24799378
P5875ResearchGate publication ID262076008

P2093author name stringYing Wang
Ping Li
Kan Ding
Fei Xiao
Ling Zhou
Hailing Liu
Xinyan Ni
Shunchun Wang
Songshan Shi
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Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?Q29616804
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Surviving cell death through epidermal growth factor (EGF) signal transduction pathways: implications for cancer therapyQ36525426
EGFRvIII and DNA double-strand break repair: a molecular mechanism for radioresistance in glioblastomaQ37223890
DNA repair and resistance of gliomas to chemotherapy and radiotherapyQ37553777
A novel small molecule, HK-156, inhibits lipopolysaccharide-induced activation of NF-κB signaling and improves survival in mouse models of sepsisQ37729477
The epidermal growth factor receptor engages receptor interacting protein and nuclear factor-kappa B (NF-kappa B)-inducing kinase to activate NF-kappa B. Identification of a novel receptor-tyrosine kinase signalosomeQ38305593
Oligosaccharide from apple induces apoptosis and cell cycle arrest in HT29 human colon cancer cellsQ39178403
Inhibition of phosphatidylinositol-3-OH kinase/Akt signaling impairs DNA repair in glioblastoma cells following ionizing radiationQ39504308
Cyclin A Promotes S-Phase Entry via Interaction with the Replication Licensing Factor Mcm7Q39631585
The epidermal growth factor receptor modulates DNA double-strand break repair by regulating non-homologous end-joiningQ39682604
Waltonitone induces human hepatocellular carcinoma cells apoptosis in vitro and in vivoQ39836076
p21 and p27 induction by silibinin is essential for its cell cycle arrest effect in prostate carcinoma cells.Q40067416
Structural features and anti-HIV-1 activity of novel polysaccharides from red algae Grateloupia longifolia and Grateloupia filicinaQ40113316
ATM mediates phosphorylation at multiple p53 sites, including Ser(46), in response to ionizing radiationQ40747424
HER-2/neu induces p53 ubiquitination via Akt-mediated MDM2 phosphorylationQ40767550
Redox-sensitive transactivation of epidermal growth factor receptor by tumor necrosis factor confers the NF-kappa B activation.Q40808041
Mitochondrial DNA damage initiates a cell cycle arrest by a Chk2-associated mechanism in mammalian cellsQ41788968
Gambogic acid mediates apoptosis as a p53 inducer through down-regulation of mdm2 in wild-type p53-expressing cancer cellsQ46318821
Antiangiogenic effects of GFP08, an agaran-type polysaccharide isolated from Grateloupia filicinaQ47610263
Transcriptional activation by p53 correlates with suppression of growth but not transformation.Q53468212
P433issue8
P921main subjectoligosaccharideQ320607
P304page(s)748-765
P577publication date2014-05-05
P1433published inGlycobiologyQ5572596
P1476titleOligosaccharide G19 inhibits U-87 MG human glioma cells growth in vitro and in vivo by targeting epidermal growth factor (EGF) and activating p53/p21 signaling
P478volume24

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cites work (P2860)
Q42659450Antitumor Exopolysaccharides Derived from Novel Marine Bacillus: Isolation, Characterization Aspect and Biological Activity
Q40257600Effect of temozolomide on the viability of musculoskeletal sarcoma cells
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Q35722027Honokiol induces cell cycle arrest and apoptosis via p53 activation in H4 human neuroglioma cells
Q38361238Role of tenascins in the ECM of gliomas
Q37028372Surgical injury induces local and distant adipose tissue browning

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