Cavin-1 regulates caveolae-mediated LDL transcytosis: crosstalk in an AMPK/eNOS/ NF-κB/Sp1 loop

scientific article

Cavin-1 regulates caveolae-mediated LDL transcytosis: crosstalk in an AMPK/eNOS/ NF-κB/Sp1 loop is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.18632/ONCOTARGET.21944
P932PMC publication ID5732781
P698PubMed publication ID29262615

P2093author name stringSi Jin
Xiong Jia
Xiao-Yan Yang
Yu-Mei Wang
Zhi-Fan Xiong
Xiang-Li Bai
Ju-Yi Li
Ye-Li
P2860cites workFunctional analysis of the human endothelial nitric oxide synthase promoter. Sp1 and GATA factors are necessary for basal transcription in endothelial cellsQ28288107
Nitric oxide inhibits endothelial IL-1[beta]-induced ICAM-1 gene expression at the transcriptional level decreasing Sp1 and AP-1 activityQ28345029
Hyperglycemia inhibits endothelial nitric oxide synthase activity by posttranslational modification at the Akt siteQ28363492
Adjacent sequence controls the response polarity of nitric oxide-sensitive Sp factor binding sitesQ40646180
Salidroside improves endothelial function and alleviates atherosclerosis by activating a mitochondria-related AMPK/PI3K/Akt/eNOS pathwayQ40723319
Vascular endothelial growth factor governs endothelial nitric-oxide synthase expression via a KDR/Flk-1 receptor and a protein kinase C signaling pathwayQ40919226
Identification of nitric oxide as an endogenous activator of the AMP-activated protein kinase in vascular endothelial cellsQ41901421
Induction and stabilization of I kappa B alpha by nitric oxide mediates inhibition of NF-kappa B.Q42486524
Sp1 transcription factor as a molecular target for nitric oxide-- and cyclic nucleotide--mediated suppression of cGMP-dependent protein kinase-Ialpha expression in vascular smooth muscle cellsQ42518390
Structural characterization of the caveolin scaffolding domain in association with cholesterol-rich membranes.Q42621806
Biogenesis of caveolae: stepwise assembly of large caveolin and cavin complexesQ43195594
AICAR administration causes an apparent enhancement of muscle and liver insulin action in insulin-resistant high-fat-fed ratsQ44155454
Direct activation of AMP-activated protein kinase stimulates nitric-oxide synthesis in human aortic endothelial cellsQ44468960
Inhibition of endothelial vascular cell adhesion molecule-1 expression by nitric oxide involves the induction and nuclear translocation of IkappaBalpha.Q54350265
TNF-α promotes early atherosclerosis by increasing transcytosis of LDL across endothelial cells: crosstalk between NF-κB and PPAR-γ.Q54389261
A novel mechanism of action for salidroside to alleviate diabetic albuminuria: effects on albumin transcytosis across glomerular endothelial cells.Q55034880
In vivo delivery of the caveolin-1 scaffolding domain inhibits nitric oxide synthesis and reduces inflammationQ60695434
Requirement of Sp1 and estrogen receptor alpha interaction in 17beta-estradiol-mediated transcriptional activation of the low density lipoprotein receptor gene expressionQ73620068
Distinct signals regulate AS160 phosphorylation in response to insulin, AICAR, and contraction in mouse skeletal muscleQ79801118
Estrogen receptor-α drives adiponectin effects on cyclin D1 expression in breast cancer cellsQ86679450
Caveolin-1 knockout mice exhibit airway hyperreactivityQ28389682
PTRF-Cavin, a conserved cytoplasmic protein required for caveola formation and functionQ28511660
Dissecting the interaction between nitric oxide synthase (NOS) and caveolin. Functional significance of the nos caveolin binding domain in vivoQ28609900
Loss of caveolae, vascular dysfunction, and pulmonary defects in caveolin-1 gene-disrupted miceQ29615180
The multiple faces of caveolaeQ29618099
Caveolin-1 induces formation of membrane tubules that sense actomyosin tension and are inhibited by polymerase I and transcript release factor/cavin-1.Q30434788
Structure-based reassessment of the caveolin signaling model: do caveolae regulate signaling through caveolin-protein interactions?Q30524349
C-reactive protein promotes atherosclerosis by increasing LDL transcytosis across endothelial cellsQ33562207
Caveolae and caveolin-1 mediate endocytosis and transcytosis of oxidized low density lipoprotein in endothelial cellsQ33577596
Salidroside stimulates mitochondrial biogenesis and protects against H₂O₂-induced endothelial dysfunctionQ33607478
Dissecting the molecular control of endothelial NO synthase by caveolin-1 using cell-permeable peptidesQ33756528
Role of histone deacetylation in cell-specific expression of endothelial nitric-oxide synthaseQ34131621
Metformin inhibits P‐glycoprotein expression via the NF‐κB pathway and CRE transcriptional activity through AMPK activationQ34148357
Regulation of gene expression by nitric oxideQ34340303
Caveolin-1 is ubiquitinated and targeted to intralumenal vesicles in endolysosomes for degradation.Q34412432
Caveolae: from cell biology to animal physiologyQ34838611
Deletion of Cavin/PTRF causes global loss of caveolae, dyslipidemia, and glucose intoleranceQ34847724
Caveolin, caveolae, and endothelial cell functionQ35104826
β-elemene inhibited expression of DNA methyltransferase 1 through activation of ERK1/2 and AMPKα signalling pathways in human lung cancer cells: the role of Sp1.Q35206525
Regulation of cellular senescence by the essential caveolar component PTRF/Cavin-1.Q35348922
Passage of low-density lipoproteins through Bruch's membrane and choroidQ35622034
Salidroside ameliorates insulin resistance through activation of a mitochondria-associated AMPK/PI3K/Akt/GSK3β pathway.Q35846190
Shear stress regulates endothelial cell autophagy via redox regulation and Sirt1 expressionQ36293891
Biogenesis of caveolae: a structural model for caveolin-induced domain formationQ36403986
Role of caveolin-1 in the regulation of lipoprotein metabolismQ36805369
Cellular spelunking: exploring adipocyte caveolaeQ36818964
Caveolae and transcytosis in endothelial cells: role in atherosclerosisQ37238390
Cavin proteins: New players in the caveolae fieldQ37723786
Caveolae as plasma membrane sensors, protectors and organizers.Q38076024
A critical role of cavin (polymerase I and transcript release factor) in caveolae formation and organization.Q38295746
A simplified probe preparation for ELISA-based NF-kappaB activity assayQ38320430
A negative feedback mechanism involving nitric oxide and nuclear factor kappa-B modulates endothelial nitric oxide synthase transcriptionQ38322185
Inhibition of NF-kappaB DNA binding by nitric oxideQ39716552
Isolation and culture of human umbilical vein endothelial cells (HUVEC).Q40051247
Oxidative stress induces premature senescence by stimulating caveolin-1 gene transcription through p38 mitogen-activated protein kinase/Sp1-mediated activation of two GC-rich promoter elementsQ40208065
Metformin inhibits cytokine-induced nuclear factor kappaB activation via AMP-activated protein kinase activation in vascular endothelial cellsQ40331177
P433issue61
P407language of work or nameEnglishQ1860
P921main subjectNF-κBQ411114
transcytosisQ615386
P304page(s)103985-103995
P577publication date2017-10-19
P1433published inOncotargetQ1573155
P1476titleCavin-1 regulates caveolae-mediated LDL transcytosis: crosstalk in an AMPK/eNOS/ NF-κB/Sp1 loop
P478volume8

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cites work (P2860)
Q91658812Modulation of Nitric Oxide Synthases by Oxidized LDLs: Role in Vascular Inflammation and Atherosclerosis Development
Q89619611Overview of Crosstalk Between Multiple Factor of Transcytosis in Blood Brain Barrier
Q54978965Ripasudil Attenuates Lipopolysaccharide (LPS)-Mediated Apoptosis and Inflammation in Pulmonary Microvascular Endothelial Cells via ROCK2/eNOS Signaling.

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