Abstract is: Robert Clarke is a Northern Irish oncology researcher and academic administrator. He is the executive director of The Hormel Institute, a professor of biochemistry, Molecular Biology and Biophysics at the University of Minnesota, and ab Adjunct Professor of Oncology at Georgetown University. With his work focused in breast cancer research, Clarke studies how hormones (endogenous and exogenous) and related factors affect breast cancer. He has authored over 340 publications, and has 5 patents awarded. His research primarily focuses on determining an individual patient’s prognosis and the likelihood that they will respond to specific systemic therapies. His laboratory also studies drug resistance and the role of cell-cell communication in affecting dormancy and responsiveness to endocrine therapies breast cancers that express the estrogen receptor. Clarke is an elected Fellow of American Association for the Advancement of Science, the Royal Society of Chemistry, the Royal Society of Medicine, and the Royal Society of Biology. He is a Senior Editor for the journal Cancer Research.
human | Q5 |
P6178 | Dimensions author ID | 010362102153.33 |
P227 | GND ID | 173880592 |
P2671 | Google Knowledge Graph ID | /g/11rxrpbtn1 |
P1960 | Google Scholar author ID | BgsjeHMAAAAJ |
P269 | IdRef ID | 197636365 |
P6634 | LinkedIn personal profile ID | robert-clarke-phd-dsc |
P2798 | Loop ID | 27488 |
P496 | ORCID iD | 0000-0002-9278-0854 |
P3829 | Publons author ID | 1541181 |
P1053 | ResearcherID | A-6485-2008 |
P2038 | ResearchGate profile ID | Robert_Clarke2 |
P1153 | Scopus author ID | 56551716900 |
P214 | VIAF cluster ID | 328148704320536932257 |
P166 | award received | Fellow of the American Association for the Advancement of Science | Q5442484 |
Fellow of the Royal Society of Chemistry | Q5442487 | ||
Fellow of the Royal Society of Medicine | Q59779997 | ||
P69 | educated at | Queen's University Belfast | Q877925 |
Ulster University | Q2096524 | ||
P108 | employer | University of Minnesota | Q238101 |
Georgetown University | Q333886 | ||
Georgetown University Medical Center | Q5547057 | ||
Georgetown University School of Medicine | Q5547065 | ||
Hormel Institute | Q24061924 | ||
P734 | family name | Clarke | Q1095787 |
Clarke | Q1095787 | ||
Clarke | Q1095787 | ||
P735 | given name | Robert | Q4927937 |
Robert | Q4927937 | ||
P106 | occupation | researcher | Q1650915 |
oncologist | Q16062369 | ||
P21 | sex or gender | male | Q6581097 |
Q31156840 | A ground truth based comparative study on clustering of gene expression data. |
Q36566887 | A maternal diet high in n − 6 polyunsaturated fats alters mammary gland development, puberty onset, and breast cancer risk among female rat offspring |
Q35843483 | A new class of small molecule estrogen receptor-alpha antagonists that overcome anti-estrogen resistance. |
Q33241980 | AIB1 gene amplification and the instability of polyQ encoding sequence in breast cancer cell lines |
Q35057264 | AISAIC: a software suite for accurate identification of significant aberrations in cancers |
Q81066714 | Acquired estrogen independence and antiestrogen resistance in breast cancer: estrogen receptor driven phenotypes? |
Q41183303 | Acquisition of an antiestrogen-resistant phenotype in breast cancer: role of cellular and molecular mechanisms. |
Q35689023 | Acquisition of estrogen independence induces TOB1-related mechanisms supporting breast cancer cell proliferation |
Q41578634 | Acquisition of hormone-independent growth in MCF-7 cells is accompanied by increased expression of estrogen-regulated genes but without detectable DNA amplifications. |
Q38406794 | Advancing Translational Research through Facility Design in Non-AMC Hospitals. |
Q54751952 | Adverse interactions between cytotoxic drugs and hormonal agents in human breast cancer cells. |
Q48445117 | Alterations in behavior, steroid hormones and natural killer cell activity in male transgenic TGF alpha mice |
Q41639361 | Analysis of tyrosine kinase mRNAs including four FGF receptor mRNAs expressed in MCF-7 breast-cancer cells |
Q41710247 | Animal models of breast cancer: experimental design and their use in nutrition and psychosocial research. |
Q36713946 | Antiestrogen Resistance and the Application of Systems Biology |
Q34272156 | Antiestrogen resistance in breast cancer and the role of estrogen receptor signaling. |
Q28268250 | Antiestrogens, aromatase inhibitors, and apoptosis in breast cancer |
Q26866291 | Application of metabolomics in drug resistant breast cancer research |
Q31147056 | Approaches to working in high-dimensional data spaces: gene expression microarrays |
Q36213244 | Aromatase inhibitor plus ovarian suppression as adjuvant therapy in premenopausal women with breast cancer |
Q38288109 | Association of interferon regulatory factor-1, nucleophosmin, nuclear factor-kappaB, and cyclic AMP response element binding with acquired resistance to Faslodex (ICI 182,780). |
Q100490944 | Author Correction: BICORN: An R package for integrative inference of de novo cis-regulatory modules |
Q77725499 | Autoantibodies to the nuclear phosphoprotein nucleophosmin in breast cancer patients |
Q27023375 | Autophagy and endocrine resistance in breast cancer |
Q57814745 | Autophagy and unfolded protein response (UPR) regulate mammary gland involution by restraining apoptosis-driven irreversible changes |
Q34518669 | Autophagy inhibitor 3-methyladenine potentiates apoptosis induced by dietary tocotrienols in breast cancer cells |
Q36039811 | BACOM2.0 facilitates absolute normalization and quantification of somatic copy number alterations in heterogeneous tumor |
Q30855028 | BADGE: a novel Bayesian model for accurate abundance quantification and differential analysis of RNA-Seq data. |
Q30432099 | BCL2 and CASP8 regulation by NF-kappaB differentially affect mitochondrial function and cell fate in antiestrogen-sensitive and -resistant breast cancer cells. |
Q94687270 | BICORN: An R package for integrative inference of de novo cis-regulatory modules |
Q35671015 | BMRF-MI: integrative identification of protein interaction network by modeling the gene dependency |
Q35574312 | BMRF-Net: a software tool for identification of protein interaction subnetworks by a bagging Markov random field-based method. |
Q30883476 | BSSV: Bayesian based somatic structural variation identification with whole genome DNA-seq data |
Q39399977 | Biologically inspired survival analysis based on integrating gene expression as mediator with genomic variants. |
Q44953213 | Biomarker identification by knowledge-driven multilevel ICA and motif analysis. |
Q45061249 | Breast cancer cell obatoclax response characterization using passivated-electrode insulator-based dielectrophoresis |
Q71878628 | Breast cancer risk in rats fed a diet high in n-6 polyunsaturated fatty acids during pregnancy |
Q43849720 | C-7 analogues of progesterone as potent inhibitors of the P-glycoprotein efflux pump. |
Q47216185 | CRNET: An efficient sampling approach to infer functional regulatory networks by integrating large-scale ChIP-seq and time-course RNA-seq data. |
Q33967143 | Cadmium mimics the in vivo effects of estrogen in the uterus and mammary gland. |
Q26995731 | Cannibalism, cell survival, and endocrine resistance in breast cancer |
Q40190072 | Caveolin-1 tyrosine phosphorylation enhances paclitaxel-mediated cytotoxicity. |
Q36817914 | ChIP-BIT: Bayesian inference of target genes using a novel joint probabilistic model of ChIP-seq profiles. |
Q113309275 | ChIP-GSM: Inferring active transcription factor modules to predict functional regulatory elements |
Q36950653 | Changes in mammary caveolin-1 signaling pathways are associated with breast cancer risk in rats exposed to estradiol in utero or during prepuberty |
Q33523022 | Co-inhibition of BCL-W and BCL2 restores antiestrogen sensitivity through BECN1 and promotes an autophagy-associated necrosis |
Q40464259 | Common origins of MDA-MB-435 cells from various sources with those shown to have melanoma properties. |
Q34918110 | Comparison of tamoxifen and letrozole response in mammary preneoplasia of ER and aromatase overexpressing mice defines an immune-associated gene signature linked to tamoxifen resistance. |
Q43513213 | Competitive and allosteric interactions in ligand binding to P-glycoprotein as observed on an immobilized P-glycoprotein liquid chromatographic stationary phase. |
Q68117728 | Conformational and receptor binding properties of human EGF and TGF-alpha second loop fragments |
Q33520897 | Cross phenotype normalization of microarray data |
Q36259785 | CyNetSVM: A Cytoscape App for Cancer Biomarker Identification Using Network Constrained Support Vector Machines. |
Q43125816 | DBC-1 mediates endocrine resistant breast cancer cell survival. |
Q33812553 | DDN: a caBIG® analytical tool for differential network analysis |
Q39402478 | DM-BLD: differential methylation detection using a hierarchical Bayesian model exploiting local dependency. |
Q112618773 | Data-driven detection of subtype-specific differentially expressed genes |
Q73614924 | Development of an immobilized P-glycoprotein stationary phase for on-line liquid chromatographic determination of drug-binding affinities |
Q41669586 | Differential distribution of protein phosphatase 2A in human breast carcinoma cell lines and its relation to estrogen receptor status. |
Q34565485 | Do estrogens always increase breast cancer risk? |
Q34487539 | Dynamic Modeling of the Interaction Between Autophagy and Apoptosis in Mammalian Cells. |
Q34192940 | Dynamic modelling of oestrogen signalling and cell fate in breast cancer cells |
Q47122770 | EGR1 regulates cellular metabolism and survival in endocrine resistant breast cancer. |
Q54313198 | ERβ decreases breast cancer cell survival by regulating the IRE1/XBP-1 pathway. |
Q70799119 | Early life affects the risk of developing breast cancer |
Q36546451 | Effect of Berry Extracts and Bioactive Compounds on Fulvestrant (ICI 182,780) Sensitive and Resistant Cell Lines |
Q43947064 | Effect of P-glycoprotein expression on sensitivity to hormones in MCF-7 human breast cancer cells |
Q69660043 | Effect of cytotoxic drugs on estrogen receptor expression and response to tamoxifen in MCF-7 cells |
Q41350093 | Effect of estrogen withdrawal on energy-rich phosphates and prediction of estrogen dependence monitored by in vivo 31P magnetic resonance spectroscopy of four human breast cancer xenografts. |
Q54216800 | Effect of tamoxifen on the multidrug-resistant phenotype in human breast cancer cells: isobologram, drug accumulation, and M(r) 170,000 glycoprotein (gp170) binding studies. |
Q38747536 | Effects of In Utero Exposure to Ethinyl Estradiol on Tamoxifen Resistance and Breast Cancer Recurrence in a Preclinical Model. |
Q61818033 | Effects of Jaeumkanghwa-tang on tamoxifen responsiveness in preclinical ER+ breast cancer model |
Q36386322 | Endocrine resistance in breast cancer--An overview and update |
Q40198514 | Endocrine therapy resistance can be associated with high estrogen receptor alpha (ERalpha) expression and reduced ERalpha phosphorylation in breast cancer models. |
Q37072811 | Endoplasmic reticulum stress, the unfolded protein response, and gene network modeling in antiestrogen resistant breast cancer |
Q35855031 | Endoplasmic reticulum stress, the unfolded protein response, autophagy, and the integrated regulation of breast cancer cell fate. |
Q68973307 | Enhancement of methotrexate cytotoxicity towards the MDA.MB.436 human breast cancer cell line by dipyridamole. The role of methotrexate polyglutamates |
Q30405622 | Enhancing reproducibility in cancer drug screening: how do we move forward? |
Q31074315 | Estrogen receptor alpha positive breast tumors and breast cancer cell lines share similarities in their transcriptome data structures. |
Q35634154 | Estrogen receptor-α signaling and localization regulates autophagy and unfolded protein response activation in ER+ breast cancer |
Q91098603 | Estrogen-Induced Apoptosis in Breast Cancers Is Phenocopied by Blocking Dephosphorylation of Eukaryotic Initiation Factor 2 Alpha (eIF2α) Protein |
Q40550409 | Expression of an estrogen receptor variant lacking exon 3 in derivatives of MCF-7 cells with acquired estrogen independence or tamoxifen resistance. |
Q38318101 | Expression patterns among interferon regulatory factor-1, human X-box binding protein-1, nuclear factor kappa B, nucleophosmin, estrogen receptor-alpha and progesterone receptor proteins in breast cancer tissue microarrays. |
Q70675151 | Failure of 5-fluorouracil and methotrexate to destroy the reproductive integrity of a human breast cancer cell line (MCF-7) growing in vitro |
Q45714359 | Functionally active estrogen receptor isoform profiles in the breast tumors of African American women are different from the profiles in breast tumors of Caucasian women. |
Q27319225 | G-DOC Plus - an integrative bioinformatics platform for precision medicine. |
Q35238047 | G-DOC: a systems medicine platform for personalized oncology |
Q44972336 | GIST: a Gibbs sampler to identify intracellular signal transduction pathways |
Q36759341 | GX15-070 (obatoclax) induces apoptosis and inhibits cathepsin D- and L-mediated autophagosomal lysis in antiestrogen-resistant breast cancer cells |
Q35069549 | Gamma-tocotrienol induced apoptosis is associated with unfolded protein response in human breast cancer cells |
Q33516560 | Gene module identification from microarray data using nonnegative independent component analysis |
Q37401741 | Gene network signaling in hormone responsiveness modifies apoptosis and autophagy in breast cancer cells |
Q35208950 | Gene selection for multiclass prediction by weighted Fisher criterion |
Q37170530 | Gene signaling pathways mediating the opposite effects of prepubertal low-fat and high-fat n-3 polyunsaturated fatty acid diets on mammary cancer risk. |
Q34354428 | Genome-wide identification of significant aberrations in cancer genome. |
Q36622926 | Glucose-regulated protein 78 controls cross-talk between apoptosis and autophagy to determine antiestrogen responsiveness |
Q92715598 | Glutamine Metabolism Drives Growth in Advanced Hormone Receptor Positive Breast Cancer |
Q47156376 | Glutamine metabolism and the unfolded protein response in MYC-driven breast cancer |
Q78222414 | Growth and phenotypic characterization of porcine coronary artery smooth muscle cells |
Q21996341 | Guidelines for the use and interpretation of assays for monitoring autophagy |
Q36521680 | Heat shock 70 kDa protein 5/glucose-regulated protein 78 “AMP”ing up autophagy |
Q35898237 | Hormonal aspects of breast cancer. Growth factors, drugs and stromal interactions |
Q40607013 | Hormonal carcinogenesis in breast cancer: cellular and molecular studies of malignant progression. |
Q41365153 | Hormone dependence of breast cancer cells and the effects of tamoxifen and estrogen: 31P NMR studies. |
Q40877540 | Hormone resistance, invasiveness, and metastatic potential in breast cancer. |
Q40101179 | Human X-box binding protein-1 confers both estrogen independence and antiestrogen resistance in breast cancer cell lines. |
Q30417594 | Identification of condition-specific regulatory modules through multi-level motif and mRNA expression analysis. |
Q73815854 | Identification of twenty alternatively spliced estrogen receptor alpha mRNAs in breast cancer cell lines and tumors using splice targeted primer approach |
Q34047245 | Identifying cancer biomarkers by network-constrained support vector machines |
Q36900433 | Identifying early events of gene expression in breast cancer with systems biology phylogenetics |
Q36559266 | Identifying protein interaction subnetworks by a bagging Markov random field-based method. |
Q36629870 | In Silico Discovery of Mitosis Regulation Networks Associated with Early Distant Metastases in Estrogen Receptor Positive Breast Cancers |
Q68059385 | In vitro antineoplastic activity of C7-substituted mitomycin C analogues MC-77 and MC-62 against human breast-cancer cell lines |
Q51903156 | Inferring network interactions using recurrent neural networks and swarm intelligence |
Q28258801 | Influence of berry polyphenols on receptor signaling and cell-death pathways: implications for breast cancer prevention |
Q37234543 | Inhibition of BET proteins impairs estrogen-mediated growth and transcription in breast cancers by pausing RNA polymerase advancement. |
Q78115556 | Inhibition of estrogen receptor function promotes porcine coronary artery smooth muscle cell proliferation |
Q67550875 | Inhibition of growth of MCF-7 MIII human breast carcinoma in nude mice by treatment with agonists or antagonists of LH-RH |
Q35142436 | Integration of Network Biology and Imaging to Study Cancer Phenotypes and Responses |
Q45245687 | Interaction of dietary polyphenols with molecular signaling pathways of antiestrogen resistance: possible role in breast cancer recurrence. |
Q35178371 | Interferon regulatory factor-1 signaling regulates the switch between autophagy and apoptosis to determine breast cancer cell fate |
Q39221896 | Introduction: Cancer Gene Networks |
Q41710325 | Issues in experimental design and endpoint analysis in the study of experimental cytotoxic agents in vivo in breast cancer and other models. |
Q30686050 | Iterative normalization of cDNA microarray data. |
Q34880603 | KDDN: an open-source Cytoscape app for constructing differential dependency networks with significant rewiring |
Q34038359 | Knowledge-fused differential dependency network models for detecting significant rewiring in biological networks |
Q33547729 | Knowledge-guided gene ranking by coordinative component analysis |
Q36023211 | LCC15-MB cells are MDA-MB-435: a review of misidentified breast and prostate cell lines |
Q44933111 | Latent variable and nICA modeling of pathway gene module composite. |
Q47873418 | Lifetime Genistein Intake Increases the Response of Mammary Tumors to Tamoxifen in Rats |
Q36836130 | Linking autophagy with inflammation through IRF1 signaling in ER+ breast cancer |
Q42809219 | MCF7/LCC2: a 4-hydroxytamoxifen resistant human breast cancer variant that retains sensitivity to the steroidal antiestrogen ICI 182,780. |
Q42815735 | MCF7/LCC9: an antiestrogen-resistant MCF-7 variant in which acquired resistance to the steroidal antiestrogen ICI 182,780 confers an early cross-resistance to the nonsteroidal antiestrogen tamoxifen |
Q36134468 | MDA435/LCC6 and MDA435/LCC6MDR1: ascites models of human breast cancer. |
Q34439115 | MYC regulates the unfolded protein response and glucose and glutamine uptake in endocrine resistant breast cancer |
Q34504376 | Maternal exposure to genistein during pregnancy increases carcinogen-induced mammary tumorigenesis in female rat offspring. |
Q73404128 | Maternal exposure to tamoxifen during pregnancy increases carcinogen-induced mammary tumorigenesis among female rat offspring |
Q48477249 | Maternal genistein exposure mimics the effects of estrogen on mammary gland development in female mouse offspring. |
Q36438365 | Mathematical modelling of transcriptional heterogeneity identifies novel markers and subpopulations in complex tissues |
Q33656026 | Mathematical models of the transitions between endocrine therapy responsive and resistant states in breast cancer. |
Q36326590 | Mechanisms mediating the effects of prepubertal (n-3) polyunsaturated fatty acid diet on breast cancer risk in rats. |
Q55041780 | Meta-analysis of soy intake and breast cancer risk. |
Q34367908 | Modeling the estrogen receptor to growth factor receptor signaling switch in human breast cancer cells |
Q37078095 | Module-based breast cancer classification |
Q34668715 | Molecular mechanisms of tamoxifen-associated endometrial cancer (Review). |
Q33584432 | Monoclonal antibody against the ectodomain of E-cadherin (DECMA-1) suppresses breast carcinogenesis: involvement of the HER/PI3K/Akt/mTOR and IAP pathways |
Q33322210 | Motif-directed network component analysis for regulatory network inference |
Q41523907 | Multidrug resistance in breast cancer: a meta-analysis of MDR1/gp170 expression and its possible functional significance. |
Q36345139 | Multidrug resistance/P-glycoprotein and breast cancer: review and meta-analysis |
Q33857304 | Multilevel support vector regression analysis to identify condition-specific regulatory networks |
Q34745409 | NF-κB signaling is required for XBP1 (unspliced and spliced)-mediated effects on antiestrogen responsiveness and cell fate decisions in breast cancer |
Q37938988 | NTP-CERHR expert panel report on the developmental toxicity of soy infant formula. |
Q35991956 | Oestrogen receptor status and the response of human breast cancer cell lines to a combination of methotrexate and 17-beta oestradiol. |
Q35976826 | Opposing behavioural alterations in male and female transgenic TGF alpha mice: association with tumour susceptibility |
Q31029221 | Optimized multilayer perceptrons for molecular classification and diagnosis using genomic data. |
Q36455407 | Orphan nuclear receptors in breast cancer pathogenesis and therapeutic response. |
Q48395472 | Overcoming cancer resistance. |
Q37165163 | Overexpression of the dominant-negative form of interferon regulatory factor 1 in oligodendrocytes protects against experimental autoimmune encephalomyelitis |
Q39360543 | PSSV: a novel pattern-based probabilistic approach for somatic structural variation identification. |
Q40607026 | Perinatal factors increase breast cancer risk. |
Q30441028 | Physical and functional interactions between Cas and c-Src induce tamoxifen resistance of breast cancer cells through pathways involving epidermal growth factor receptor and signal transducer and activator of transcription 5b. |
Q61805769 | Poly-ADP-Ribosylation of Estrogen Receptor-Alpha by PARP1 Mediates Antiestrogen Resistance in Human Breast Cancer Cells |
Q48438001 | Profile of Robert Clarke. Interviewed by Kristie Nybo, Ph.D. |
Q33857080 | Progression of human breast cancer cells from hormone-dependent to hormone-independent growth both in vitro and in vivo. |
Q40100025 | Progressive loss of estrogen receptor alpha cofactor recruitment in endocrine resistance. |
Q40661647 | Psychosocial factors in the development and progression of breast cancer. |
Q47151773 | RNA Interference Screening to Identify Proliferation Determinants in Breast Cancer Cells. |
Q90365558 | RNA interference screening methods to identify proliferation determinants and mechanisms of resistance to immune attack |
Q99727664 | Radiogenomic signatures reveal multiscale intratumour heterogeneity associated with biological functions and survival in breast cancer |
Q33565567 | Reconstruction of gene regulatory modules in cancer cell cycle by multi-source data integration |
Q36840512 | Reconstruction of transcriptional regulatory networks by stability-based network component analysis. |
Q71230912 | Reduction of the anti-metabolic and anti-proliferative effects of methotrexate by 17 beta-oestradiol in a human breast carcinoma cell line, MDA-MB-436 |
Q68589706 | Reduction of the membrane fluidity of human breast cancer cells by tamoxifen and 17 beta-estradiol |
Q36009608 | Regulatory component analysis: A semi-blind extraction approach to infer gene regulatory networks with imperfect biological knowledge |
Q41492304 | Resistance to TNF-alpha and adriamycin in the human breast cancer MCF-7 cell line: relationship to MDR1, MnSOD, and TNF gene expression. |
Q54108530 | Reversal of tamoxifen resistance of human breast carcinomas in vivo by neutralizing antibodies to transforming growth factor-beta. |
Q33481221 | Reverse engineering module networks by PSO-RNN hybrid modeling |
Q57676341 | Robust identification of transcriptional regulatory networks using a Gibbs sampler on outlier sum statistic |
Q36143861 | Role of GRP78 in promoting therapeutic-resistant breast cancer |
Q34603057 | Small-molecule "BRCA1-mimetics" are antagonists of estrogen receptor-α |
Q50172986 | Social isolation induces autophagy in the mouse mammary gland: link to increased mammary cancer risk. |
Q42696647 | SparseIso: A novel Bayesian approach to identify alternatively spliced isoforms from RNA-seq data |
Q41066361 | Steroid metabolism in the hormone dependent MCF-7 human breast carcinoma cell line and its two hormone resistant subpopulations MCF-7/LCC1 and MCF-7/LCC2. |
Q92971911 | Systems biology: perspectives on multiscale modeling in research on endocrine-related cancers |
Q28115071 | TMEM33: a new stress-inducible endoplasmic reticulum transmembrane protein and modulator of the unfolded protein response signaling |
Q40133661 | The A4396G polymorphism in interferon regulatory factor 1 is frequently expressed in breast cancer cell lines. |
Q35684410 | The Role of Interferon Regulatory Factor-1 (IRF1) in Overcoming Antiestrogen Resistance in the Treatment of Breast Cancer. |
Q68939682 | The effect of leucovorin on the synthesis of methotrexate poly-gamma-glutamates in the MCF-7 human breast cancer cell line |
Q43558847 | The effect of the rate of cell proliferation on the synthesis of methotrexate poly-gamma-glutamates in two human breast cancer cell lines. |
Q52490490 | The effects of Mg2+ ions or EDTA on nuclear integrity and apparent subcellular distribution of unoccupied oestrogen receptors in breast cancer cells. |
Q41306567 | The effects of a constitutive expression of transforming growth factor-alpha on the growth of MCF-7 human breast cancer cells in vitro and in vivo. |
Q43781864 | The enantioselective binding of mefloquine enantiomers to P-glycoprotein determined using an immobilized P-glycoprotein liquid chromatographic stationary phase. |
Q42809581 | The invasive and metastatic properties of hormone-independent but hormone-responsive variants of MCF-7 human breast cancer cells. |
Q72691580 | The kinetics of methotrexate polyglutamate formation and efflux in a human breast cancer cell line (MDA.MB.436): the effect of insulin |
Q54299947 | The multidrug resistance phenotype: 31P nuclear magnetic resonance characterization and 2-deoxyglucose toxicity. |
Q24815528 | The nuclear factor kappa B inhibitor parthenolide restores ICI 182,780 (Faslodex; fulvestrant)-induced apoptosis in antiestrogen-resistant breast cancer cells |
Q40417107 | The p160 family coactivators regulate breast cancer cell proliferation and invasion through autocrine/paracrine activity of SDF-1alpha/CXCL12. |
Q39713570 | The proapoptotic molecule BLID interacts with Bcl-XL and its downregulation in breast cancer correlates with poor disease-free and overall survival. |
Q31140694 | The properties of high-dimensional data spaces: implications for exploring gene and protein expression data. |
Q37553966 | The role of X-box binding protein-1 in tumorigenicity. |
Q33555575 | The role of preclinical animal models in breast cancer drug development |
Q69411578 | The unoccupied estrogen receptor: some comments on localization |
Q30419997 | Therapeutically activating RB: reestablishing cell cycle control in endocrine therapy-resistant breast cancer |
Q77582009 | Timing of dietary fat exposure and mammary tumorigenesis: role of estrogen receptor and protein kinase C activity |
Q74465247 | Two-dimensional gel electrophoresis analyses identify nucleophosmin as an estrogen regulated protein associated with acquired estrogen-independence in human breast cancer cells |
Q36006854 | Tyrosine-phosphorylated caveolin-1 (Tyr-14) increases sensitivity to paclitaxel by inhibiting BCL2 and BCLxL proteins via c-Jun N-terminal kinase (JNK). |
Q34737311 | UNDO: a Bioconductor R package for unsupervised deconvolution of mixed gene expressions in tumor samples. |
Q35763853 | Unfolding the Role of Stress Response Signaling in Endocrine Resistant Breast Cancers. |
Q34473011 | Unsupervised deconvolution of dynamic imaging reveals intratumor vascular heterogeneity and repopulation dynamics |
Q40984803 | Use of ERE and reporter gene constructs to assess putative estrogenic activity. |
Q33827037 | VAV3 mediates resistance to breast cancer endocrine therapy. |
Q35648915 | Vitamin E succinate inhibits survivin and induces apoptosis in pancreatic cancer cells |
Q35096599 | When is a vesicle not just a vesicle: mitochondrial spheroids and mitochondrial autophagosomes |
Q33370429 | caBIG VISDA: modeling, visualization, and discovery for cluster analysis of genomic data |
Q40550091 | interferon regulatory factor-1 mediates the proapoptotic but not cell cycle arrest effects of the steroidal antiestrogen ICI 182,780 (faslodex, fulvestrant). |
Q33640925 | mAPC-GibbsOS: an integrated approach for robust identification of gene regulatory networks. |
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