Assembly of phospholipid nanodiscs of controlled size for structural studies of membrane proteins by NMR.

scientific article published on 7 December 2017

Assembly of phospholipid nanodiscs of controlled size for structural studies of membrane proteins by NMR. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/NPROT.2017.094
P932PMC publication ID5806515
P698PubMed publication ID29215632

P2093author name stringGerhard Wagner
Franz Hagn
Mahmoud L Nasr
P2860cites workThe structure of the integrin alphaIIbbeta3 transmembrane complex explains integrin transmembrane signallingQ24320948
Attenuated T2 relaxation by mutual cancellation of dipole-dipole coupling and chemical shift anisotropy indicates an avenue to NMR structures of very large biological macromolecules in solutionQ24649924
Membrane lipids: where they are and how they behaveQ24653084
Unique dimeric structure of BNip3 transmembrane domain suggests membrane permeabilization as a cell death triggerQ27644370
Optimized Phospholipid Bilayer Nanodiscs Facilitate High-Resolution Structure Determination of Membrane ProteinsQ27675772
Measuring membrane protein bond orientations in nanodiscs via residual dipolar couplingsQ27683495
Applications of non-uniform sampling and processing.Q27693218
The CCPN data model for NMR spectroscopy: development of a software pipelineQ27860601
NMRPipe: a multidimensional spectral processing system based on UNIX pipesQ27860859
Tobacco etch virus protease: mechanism of autolysis and rational design of stable mutants with wild-type catalytic proficiencyQ28216587
Inside-out Ca(2+) signalling prompted by STIM1 conformational switch.Q28265152
Tunable alignment of macromolecules by filamentous phage yields dipolar coupling interactionsQ28290988
TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid actionQ28574929
Crystallizing membrane proteins using lipidic mesophasesQ29616431
Utilization of site-directed spin labeling and high-resolution heteronuclear nuclear magnetic resonance for global fold determination of large proteins with limited nuclear overhauser effect dataQ29617299
Covalently circularized nanodiscs for studying membrane proteins and viral entryQ30152700
Optimizing nanodiscs and bicelles for solution NMR studies of two β-barrel membrane proteinsQ30152951
Characterization of the insertase BamA in three different membrane mimetics by solution NMR spectroscopyQ30153242
Solution-NMR characterization of outer-membrane protein A from E. coli in lipid bilayer nanodiscs and detergent micellesQ30153417
Accelerated acquisition of high resolution triple-resonance spectra using non-uniform sampling and maximum entropy reconstruction.Q30342740
Isotope labeling strategies for the study of high-molecular-weight proteins by solution NMR spectroscopy.Q30360846
Single-particle electron microscopy in the study of membrane protein structureQ30380310
Recent contributions from solid-state NMR to the understanding of membrane protein structure and functionQ30406314
The Use of Residual Dipolar Coupling in Studying Proteins by NMRQ30407518
NMR studies of the anti-apoptotic protein Bcl-xL in micellesQ30613316
Conformation of BCL-XL upon Membrane IntegrationQ30902649
Characterization of the membrane-inserted C-terminus of cytoprotective BCL-XL.Q31049767
Insights from biophysical studies on the role of polyunsaturated fatty acids for function of G-protein coupled membrane receptorsQ33384060
Poisson-gap sampling and forward maximum entropy reconstruction for enhancing the resolution and sensitivity of protein NMR dataQ33528062
Membrane lipid composition and cellular functionQ34051085
Application of iterative soft thresholding for fast reconstruction of NMR data non-uniformly sampled with multidimensional Poisson Gap schedulingQ34158085
Applications of phospholipid bilayer nanodiscs in the study of membranes and membrane proteins.Q34607664
Transducin activation by nanoscale lipid bilayers containing one and two rhodopsinsQ34613826
Magic-angle spinning solid-state NMR spectroscopy of nanodisc-embedded human CYP3A4.Q34710847
Membrane protein assembly into NanodiscsQ35008328
Chapter 11 - Reconstitution of membrane proteins in phospholipid bilayer nanodiscsQ35012211
Lipid-protein interactions in biological membranes: a structural perspectiveQ35120901
Conformational transitions in the membrane scaffold protein of phospholipid bilayer nanodiscsQ35264725
Solid-state NMR of the Yersinia pestis outer membrane protein Ail in lipid bilayer nanodiscs sedimented by ultracentrifugationQ35434247
Solution NMR spectroscopic characterization of human VDAC-2 in detergent micelles and lipid bilayer nanodiscsQ35874850
Membrane proteins, lipids and detergents: not just a soap opera.Q35935390
Exocytotic fusion pores are composed of both lipids and proteinsQ36589148
Exploring signal-to-noise ratio and sensitivity in non-uniformly sampled multi-dimensional NMR spectraQ36605239
Reconstitution of G protein-coupled receptors into a model bilayer system: reconstituted high-density lipoprotein particlesQ36638306
TROSY in triple-resonance experiments: new perspectives for sequential NMR assignment of large proteinsQ36793550
Non-uniformly sampled double-TROSY hNcaNH experiments for NMR sequential assignments of large proteinsQ36857023
NMR structural investigation of the mitochondrial outer membrane protein VDAC and its interaction with antiapoptotic Bcl-xL.Q36963944
Functional studies of N‐terminally modified CYP2J2 epoxygenase in model lipid bilayersQ37034584
Conformational dynamics of a G-protein α subunit is tightly regulated by nucleotide bindingQ37065226
Crystallizing membrane proteins for structure determination: use of lipidic mesophasesQ37351974
Structural and functional characterization of the integral membrane protein VDAC-1 in lipid bilayer nanodiscsQ37475250
Detergents: an overviewQ37628103
An annular lipid belt is essential for allosteric coupling and viral inhibition of the antigen translocation complex TAP (transporter associated with antigen processing).Q38948951
Solution structure of discoidal high-density lipoprotein particles with a shortened apolipoprotein A-I.Q39064223
Structure refinement and membrane positioning of selectively labeled OmpX in phospholipid nanodiscsQ39673918
Replacement of endogenous cholesteryl esters of low density lipoprotein with exogenous cholesteryl linoleate. Reconstitution of a biologically active lipoprotein particleQ40152322
The use of 2H, 13C, 15N multidimensional NMR to study the structure and dynamics of proteinsQ40853355
Cell-free expressed bacteriorhodopsin in different soluble membrane mimetics: biophysical properties and NMR accessibility.Q41224711
Stereospecific isotopic labeling of methyl groups for NMR spectroscopic studies of high-molecular-weight proteinsQ43161110
Ultrahigh-resolution (1)H-(13)C HSQC spectra of metabolite mixtures using nonlinear sampling and forward maximum entropy reconstructionQ43193514
Lipid-binding studies of human apolipoprotein A-I and its terminally truncated mutantsQ44649936
Directed self-assembly of monodisperse phospholipid bilayer Nanodiscs with controlled sizeQ44802076
Lipid-protein nanodiscs promote in vitro folding of transmembrane domains of multi-helical and multimeric membrane proteinsQ45410607
An efficient protocol for the complete incorporation of methyl-protonated alanine in perdeuterated protein.Q46179922
Modified lipid and protein dynamics in nanodiscsQ46287422
Effective rotational correlation times of proteins from NMR relaxation interference.Q46724094
Optimizing resolution in multidimensional NMR by three-way decompositionQ47696644
Membrane-dependent modulation of the mTOR activator Rheb: NMR observations of a GTPase tethered to a lipid-bilayer nanodiscQ48162743
Improved resolution in triple-resonance spectra by nonlinear sampling in the constant-time domainQ52374408
Reconstitution of the SecY translocon in nanodiscsQ54386946
Membrane interactions of dynorphins.Q54548333
Self-Assembly of Discoidal Phospholipid Bilayer Nanoparticles with Membrane Scaffold ProteinsQ56770804
A robust and cost-effective method for the production of Val, Leu, Ile (delta 1) methyl-protonated 15N-, 13C-, 2H-labeled proteinsQ57851005
Automatic maximum entropy spectral reconstruction in NMRQ58284799
Persistent contrast enhancement by sterically stabilized paramagnetic liposomes in murine melanomaQ58619128
Reconstitution of Membrane Proteins into Lipid-Rich Bilayered Mixed Micelles for NMR StudiesQ72109555
A simple biosynthetic method for stereospecific resonance assignment of prochiral methyl groups in proteinsQ83347076
P433issue1
P921main subjectmembrane proteinQ423042
P304page(s)79-98
P577publication date2017-12-07
P1433published inNature ProtocolsQ3337109
P1476titleAssembly of phospholipid nanodiscs of controlled size for structural studies of membrane proteins by NMR.
P478volume13

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cites work (P2860)
Q64108004Elucidating the Lipid Binding Properties of Membrane-Active Peptides Using Cyclised Nanodiscs
Q94521899FDA-approved disulfiram inhibits pyroptosis by blocking gasdermin D pore formation
Q90092955Hydrogen-Deuterium Exchange Mass-Spectrometry of Secondary Active Transporters: From Structural Dynamics to Molecular Mechanisms
Q89142074Macrodiscs Comprising SMALPs for Oriented Sample Solid-State NMR Spectroscopy of Membrane Proteins
Q90142133Metal-Chelated Polymer Nanodiscs for NMR Studies
Q92356441Peptide-based NTA(Ni)-nanodiscs for studying membrane enhanced FGFR1 kinase activities
Q58609850Reconstituted Discoidal High-Density Lipoproteins: Bioinspired Nanodiscs with Many Unexpected Applications
Q57799755Structural and functional insights into the interaction and targeting hub TMD0 of the polypeptide transporter TAPL
Q92145320Styrene maleic acid derivates to enhance the applications of bio-inspired polymer based lipid-nanodiscs
Q64992479Supramolecular Organization of Apolipoprotein-A-I-Derived Peptides within Disc-like Arrangements.
Q92224343The energetics of protein-lipid interactions as viewed by molecular simulations
Q91891438The hydrodynamic motion of Nanodiscs
Q90752351Two Distinct Structures of Membrane-associated Homodimers of GTP- and GDP-bound KRAS4B Revealed by Paramagnetic Relaxation Enhancement

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