MPK1/SLT2 Links Multiple Stress Responses with Gene Expression in Budding Yeast by Phosphorylating Tyr1 of the RNAP II CTD.

scientific article published in December 2017

MPK1/SLT2 Links Multiple Stress Responses with Gene Expression in Budding Yeast by Phosphorylating Tyr1 of the RNAP II CTD. is …
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scholarly articleQ13442814

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P356DOI10.1016/J.MOLCEL.2017.11.020
P932PMC publication ID5736309
P698PubMed publication ID29220656

P2093author name stringBin Tian
Mainul Hoque
Takashi Yamazaki
James L Manley
Xiaochuan Liu
Nathan Yurko
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Mpk1 MAPK association with the Paf1 complex blocks Sen1-mediated premature transcription termination.Q27934234
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Histone deacetylases and phosphorylated polymerase II C-terminal domain recruit Spt6 for cotranscriptional histone reassemblyQ34592694
Individual letters of the RNA polymerase II CTD code govern distinct gene expression programs in fission yeastQ35109917
Regulation of cell wall biogenesis in Saccharomyces cerevisiae: the cell wall integrity signaling pathwayQ35620450
Sumoylation of transcription factor Gcn4 facilitates its Srb10-mediated clearance from promoters in yeastQ35788934
Heptad-Specific Phosphorylation of RNA Polymerase II CTD.Q35901477
Biology of the heat shock response and protein chaperones: budding yeast (Saccharomyces cerevisiae) as a model system.Q36023274
TORC1 controls G1-S cell cycle transition in yeast via Mpk1 and the greatwall kinase pathwayQ36085522
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Comprehensive RNA Polymerase II Interactomes Reveal Distinct and Varied Roles for Each Phospho-CTD Residue.Q37139080
Variants of the yeast MAPK Mpk1 are fully functional independently of activation loop phosphorylation.Q37222563
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RNAP II CTD phosphorylated on threonine-4 is required for histone mRNA 3' end processingQ39448117
Transcription-independent phosphorylation of the RNA polymerase II C-terminal domain (CTD) involves ERK kinases (MEK1/2).Q39729551
Transcribing RNA polymerase II is phosphorylated at CTD residue serine-7.Q40035560
Serine-7 of the RNA polymerase II CTD is specifically required for snRNA gene expressionQ40035566
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Suppression analysis reveals a functional difference between the serines in positions two and five in the consensus sequence of the C-terminal domain of yeast RNA polymerase IIQ41932256
Saccharomyces cerevisiae Yak1p protein kinase autophosphorylates on tyrosine residues and phosphorylates myelin basic protein on a C-terminal serine residueQ41935011
The yeast mitogen-activated protein kinase Slt2 is involved in the cellular response to genotoxic stressQ42034752
Multiple faces of the SAGA complexQ42045741
Stress-induced response, localization, and regulation of the Pmk1 cell integrity pathway in Schizosaccharomyces pombeQ42486568
Cell cycle population effects in perturbation studiesQ42593231
A protein kinase gene complements the lytic phenotype of Saccharomyces cerevisiae lyt2 mutants.Q42619371
Construction and analysis of yeast RNA polymerase II CTD deletion and substitution mutations.Q42965782
Analysis of the budding yeast Saccharomyces cerevisiae cell cycle by morphological criteria and flow cytometry.Q44768641
Synthetic genetic array analysis in Saccharomyces cerevisiae.Q46885794
Association of an activator with an RNA polymerase II holoenzymeQ48074470
Genome-wide identification of genes required for growth of Saccharomyces cerevisiae under ethanol stress.Q50734378
The RNA polymerase II CTD "orphan" residues: Emerging insights into the functions of Tyr-1, Thr-4, and Ser-7.Q53128313
CTD tyrosine phosphorylation impairs termination factor recruitment to RNA polymerase II.Q54500955
Role of calcineurin and Mpk1 in regulating the onset of mitosis in budding yeastQ59097400
Serine-7 but not serine-5 phosphorylation primes RNA polymerase II CTD for P-TEFb recognitionQ61207379
Characterization of the Residues Phosphorylated in Vitro by Different C-terminal Domain KinasesQ63362926
Activated signal transduction kinases frequently occupy target genesQ80011658
P433issue5
P921main subjectphosphorylationQ242736
P304page(s)913-925.e3
P577publication date2017-12-01
P1433published inMolecular CellQ3319468
P1476titleMPK1/SLT2 Links Multiple Stress Responses with Gene Expression in Budding Yeast by Phosphorylating Tyr1 of the RNAP II CTD.
P478volume68