Postsynaptic density protein transcripts are differentially modulated by minocycline alone or in add-on to haloperidol: Implications for treatment resistant schizophrenia.

scientific article published on 21 July 2016

Postsynaptic density protein transcripts are differentially modulated by minocycline alone or in add-on to haloperidol: Implications for treatment resistant schizophrenia. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1177/0269881116658987
P698PubMed publication ID27443599

P50authorRodolfo RossiQ63364328
Paolo ChiodiniQ37841178
P2093author name stringAndrea de Bartolomeis
Carmine Tomasetti
Felice Iasevoli
Elisabetta F Buonaguro
Federica Marmo
Gianmarco Latte
Livia Avvisati
P2860cites workGlutamatergic drugs for schizophrenia: a systematic review and meta-analysisQ22251177
A novel mechanism of action of tetracyclines: effects on nitric oxide synthasesQ24680257
Arc/Arg3.1 interacts with the endocytic machinery to regulate AMPA receptor traffickingQ24681745
A double-blind, randomized study of minocycline for the treatment of negative and cognitive symptoms in early-phase schizophreniaQ28263942
Minocycline benefits negative symptoms in early schizophrenia: a randomised double-blind placebo-controlled clinical trial in patients on standard treatmentQ28265163
Minocycline add-on to risperidone for treatment of negative symptoms in patients with stable schizophrenia: randomized double-blind placebo-controlled studyQ28306923
Minocycline supplementation for treatment of negative symptoms in early-phase schizophrenia: a double blind, randomized, controlled trialQ28307393
Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responsesQ29618915
Dysbindin-1 modulates prefrontal cortical activity and schizophrenia-like behaviors via dopamine/D2 pathways.Q30465987
Mice lacking the AMPA GluR1 receptor exhibit striatal hyperdopaminergia and 'schizophrenia-related' behaviorsQ42628411
Functional neuroimaging of minocycline's effect in a patient with schizophreniaQ43170176
Minocycline inhibits cytochrome c release and delays progression of amyotrophic lateral sclerosis in miceQ43977943
Minocycline slows disease progression in a mouse model of amyotrophic lateral sclerosisQ44149270
Homer 1a gene expression modulation by antipsychotic drugs: involvement of the glutamate metabotropic system and effects of D-cycloserineQ44237544
Method for quantitative in situ hybridization histochemistry and image analysis applied for Homer1a gene expression in rat brainQ44501347
Different effects of the NMDA receptor antagonists ketamine, MK-801, and memantine on postsynaptic density transcripts and their topography: role of Homer signaling, and implications for novel antipsychotic and pro-cognitive targets in psychosisQ45283684
Nitric oxide stimulates Ca(2+)-independent synaptic vesicle release.Q46024772
Evaluation of the pro-cognitive effects of the AMPA receptor positive modulator, 5-(1-piperidinylcarbonyl)-2,1,3-benzoxadiazole (CX691), in the rat.Q46067102
Dopamine receptor subtypes contribution to Homer1a induction: insights into antipsychotic molecular actionQ46109007
Imaging brain gene expression profiles by antipsychotics: region-specific action of amisulpride on postsynaptic density transcripts compared to haloperidolQ46219167
Glutamate and the neural basis of the subjective effects of ketamine: a pharmaco-magnetic resonance imaging studyQ46771704
Neuroprotectant minocycline depresses glutamatergic neurotransmission and Ca(2+) signalling in hippocampal neurons.Q46912355
Homer splice variants modulation within cortico-subcortical regions by dopamine D2 antagonists, a partial agonist, and an indirect agonist: implication for glutamatergic postsynaptic density in antipsychotics actionQ46966416
Improvement by minocycline of methamphetamine-induced impairment of recognition memory in miceQ46971610
Minocycline as add-on treatment decreases the negative symptoms of schizophrenia; a randomized placebo-controlled clinical trialQ48184666
Differential expression of Homer 1 gene by acute and chronic administration of antipsychotics and dopamine transporter inhibitors in the rat forebrainQ48234714
Transient neuroprotection by minocycline following traumatic brain injury is associated with attenuated microglial activation but no changes in cell apoptosis or neutrophil infiltration.Q48328477
Possible antipsychotic effects of minocycline in patients with schizophreniaQ48400463
Effects of minocycline add-on treatment on brain morphometry and cerebral perfusion in recent-onset schizophreniaQ48416426
Protective effects of minocycline on 3,4-methylenedioxymethamphetamine-induced neurotoxicity in serotonergic and dopaminergic neurons of mouse brain.Q48465777
Protective effects of minocycline on behavioral changes and neurotoxicity in mice after administration of methamphetamine.Q48472593
Neuroleptics increase c-fos expression in the forebrain: contrasting effects of haloperidol and clozapineQ48594909
Regulation of postsynaptic plasticity genes' expression and topography by sustained dopamine perturbation and modulation by acute memantine: relevance to schizophreniaQ48659194
Minocycline but not tigecycline is neuroprotective and reduces the neuroinflammatory response induced by the superimposition of sepsis upon traumatic brain injuryQ48785510
The acute and chronic effects of combined antipsychotic-mood stabilizing treatment on the expression of cortical and striatal postsynaptic density genesQ48967410
Peroxynitrite inhibits glutamate transporter subtypesQ49057961
Promising use of minocycline augmentation with clozapine in treatment-resistant schizophrenia.Q50653774
Ketamine-induced NMDA receptor hypofunction as a model of memory impairment and psychosis.Q51481467
Nitric oxide inhibits 3H-glutamate transport in synaptosomes.Q52271960
Epidermal immunization by a needle-free powder delivery technology: Immunogenicity of influenza vaccine and protection in miceQ56772848
TetracyclinesQ57533398
Dysfunctional and compensatory prefrontal cortical systems, genes and the pathogenesis of schizophreniaQ33295367
De novo CNV analysis implicates specific abnormalities of postsynaptic signalling complexes in the pathogenesis of schizophrenia.Q33398247
Tetracyclines inhibit microglial activation and are neuroprotective in global brain ischemiaQ33612679
To model a psychiatric disorder in animals: schizophrenia as a reality testQ33913794
Minocycline prevents nigrostriatal dopaminergic neurodegeneration in the MPTP model of Parkinson's diseaseQ33952130
Mouse models of genetic effects on cognition: relevance to schizophreniaQ34183979
Efficacy and tolerability of minocycline augmentation therapy in schizophrenia: a systematic review and meta-analysis of randomized controlled trialsQ34432085
Homeostatic scaling requires group I mGluR activation mediated by Homer1aQ34455735
Arc-dependent synapse-specific homeostatic plasticityQ34490539
Protective effects of minocycline on the reduction of dopamine transporters in the striatum after administration of methamphetamine: a positron emission tomography study in conscious monkeys.Q34567678
Glutamate receptor dysfunction and schizophreniaQ34719075
Neuronal nitric oxide contributes to neuroplasticity-associated protein expression through cGMP, protein kinase G, and extracellular signal-regulated kinaseQ35033344
Prospects for minocycline neuroprotectionQ35079515
Gender differences and the effects of ketamine in healthy volunteers.Q35883433
Minocycline inhibits caspase-independent and -dependent mitochondrial cell death pathways in models of Huntington's diseaseQ35918549
Phosphorylation of AMPA receptors: mechanisms and synaptic plasticityQ36356588
Pharmacological treatment of primary negative symptoms in schizophrenia: a systematic reviewQ36576234
A tetracycline derivative, minocycline, reduces inflammation and protects against focal cerebral ischemia with a wide therapeutic windowQ36678875
Epileptiform stimulus increases Homer 1a expression to modulate synapse number and activity in hippocampal culturesQ36700675
Enhancement by interleukin-1β of AMPA and NMDA receptor-mediated currents in adult rat spinal superficial dorsal horn neuronsQ36755430
Minocycline increases phosphorylation and membrane insertion of neuronal GluR1 receptorsQ37018365
Modulation of behavior by scaffolding proteins of the post-synaptic densityQ37161173
Neuroinflammation is associated with changes in glial mGluR5 expression and the development of neonatal excitotoxic lesionsQ37698259
New views of Arc, a master regulator of synaptic plasticityQ37833492
Targeting glutamate system for novel antipsychotic approaches: relevance for residual psychotic symptoms and treatment resistant schizophrenia.Q37990329
Calcium-dependent networks in dopamine-glutamate interaction: the role of postsynaptic scaffolding proteins.Q38024032
Capturing the angel in "angel dust": twenty years of translational neuroscience studies of NMDA receptor antagonists in animals and humansQ38035216
Scaffolding proteins of the post-synaptic density contribute to synaptic plasticity by regulating receptor localization and distribution: relevance for neuropsychiatric diseasesQ38044699
Intracellular pathways of antipsychotic combined therapies: implication for psychiatric disorders treatment.Q38120101
Molecular mechanisms of homeostatic synaptic downscalingQ38126274
The glutamatergic aspects of schizophrenia molecular pathophysiology: role of the postsynaptic density, and implications for treatmentQ38213709
Minocycline, a second-generation tetracycline, as a neuroprotective agent in an animal model of schizophreniaQ40214962
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectschizophreniaQ41112
haloperidolQ251347
minocyclineQ415336
P304page(s)406-417
P577publication date2016-07-19
P1433published inJournal of PsychopharmacologyQ6295819
P1476titlePostsynaptic density protein transcripts are differentially modulated by minocycline alone or in add-on to haloperidol: Implications for treatment resistant schizophrenia
P478volume31

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cites work (P2860)
Q47871481Immediate-Early Genes Modulation by Antipsychotics: Translational Implications for a Putative Gateway to Drug-Induced Long-Term Brain Changes.
Q38770806Treating the Synapse in Major Psychiatric Disorders: The Role of Postsynaptic Density Network in Dopamine-Glutamate Interplay and Psychopharmacologic Drugs Molecular Actions

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