Notch is required for the formation of all nephron segments and primes nephron progenitors for differentiation

scientific article published on 7 November 2017

Notch is required for the formation of all nephron segments and primes nephron progenitors for differentiation is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1242/DEV.156661
P932PMC publication ID5769624
P698PubMed publication ID29113990

P50authorJoo-Seop ParkQ87634393
P2093author name stringEunah Chung
Patrick Deacon
P2860cites workMastermind recruits CycC:CDK8 to phosphorylate the Notch ICD and coordinate activation with turnoverQ24315524
Notch signaling controls multiple steps of pancreatic differentiationQ24569636
Identification of a conserved negative regulatory sequence that influences the leukemogenic activity of NOTCH1Q24670708
Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locusQ24797230
Nephron Patterning: Lessons from Xenopus, Zebrafish, and Mouse StudiesQ26785918
Generalized lacZ expression with the ROSA26 Cre reporter strainQ27860837
Development of the Mammalian KidneyQ28069920
The mesenchymal cell, its role in the embryo, and the remarkable signaling mechanisms that create itQ28254798
Wnt/beta-catenin signaling regulates nephron induction during mouse kidney developmentQ28506499
Epithelial transformation of metanephric mesenchyme in the developing kidney regulated by Wnt-4Q28508296
Gamma-secretase activity is dispensable for mesenchyme-to-epithelium transition but required for podocyte and proximal tubule formation in developing mouse kidneyQ28512634
HNF1B controls proximal-intermediate nephron segment identity in vertebrates by regulating Notch signalling components and Irx1/2Q28586088
Six2 is required for suppression of nephrogenesis and progenitor renewal in the developing kidneyQ28586205
Distinct and sequential tissue-specific activities of the LIM-class homeobox gene Lim1 for tubular morphogenesis during kidney developmentQ28587889
Six2 defines and regulates a multipotent self-renewing nephron progenitor population throughout mammalian kidney developmentQ28592487
Notch activation induces apoptosis in neural progenitor cells through a p53-dependent pathwayQ28592687
Notch-RBP-J signaling is involved in cell fate determination of marginal zone B cellsQ28594415
Six2 and Wnt regulate self-renewal and commitment of nephron progenitors through shared gene regulatory networksQ28594605
The canonical Notch signaling pathway: unfolding the activation mechanismQ29547725
The contribution of Notch1 to nephron segmentation in the developing kidney is revealed in a sensitized Notch2 background and can be augmented by reducing Mint dosage.Q33615861
Single cell dissection of early kidney development: multilineage primingQ34341652
Intrinsic epithelial cells repair the kidney after injuryQ34765013
Notch pathway activation can replace the requirement for Wnt4 and Wnt9b in mesenchymal-to-epithelial transition of nephron stem cellsQ35208718
Deep Sequencing in Microdissected Renal Tubules Identifies Nephron Segment-Specific TranscriptomesQ35589079
The intracellular domains of Notch1 and Notch2 are functionally equivalent during development and carcinogenesisQ35878150
High-resolution gene expression analysis of the developing mouse kidney defines novel cellular compartments within the nephron progenitor populationQ37356678
Notch signaling promotes nephrogenesis by downregulating Six2.Q37425842
Nephron progenitor cells: shifting the balance of self-renewal and differentiationQ38179668
Pronephric tubule formation in zebrafish: morphogenesis and migration.Q38760594
Cessation of renal morphogenesis in miceQ40007459
Notch2 activation in the embryonic kidney depletes nephron progenitorsQ40404328
Differential expression and function of cadherin-6 during renal epithelium developmentQ41046051
Notch2, but not Notch1, is required for proximal fate acquisition in the mammalian nephron.Q43213014
Hepatocyte nuclear factor 1β controls nephron tubular developmentQ45345858
Notch signaling controls the differentiation of transporting epithelia and multiciliated cells in the zebrafish pronephrosQ47073212
Nephron formation adopts a novel spatial topology at cessation of nephrogenesis.Q51852105
Analysis of early nephron patterning reveals a role for distal RV proliferation in fusion to the ureteric tip via a cap mesenchyme-derived connecting segment.Q51933152
Generation of new Notch2 mutant alleles.Q54623726
Podocyte-specific expression of cre recombinase in transgenic miceQ57740867
Human intrauterine renal growth expressed in absolute number of glomeruli assessed by the disector method and Cavalieri principleQ70180580
Insertion of Cre into the Pax3 locus creates a new allele of Splotch and identifies unexpected Pax3 derivativesQ81729304
P433issue24
P407language of work or nameEnglishQ1860
P1104number of pages10
P304page(s)4530-4539
P577publication date2017-11-07
P1433published inDevelopmentQ3025404
P1476titleNotch is required for the formation of all nephron segments and primes nephron progenitors for differentiation
P478volume144