scholarly article | Q13442814 |
P356 | DOI | 10.1038/ONC.2017.350 |
P8608 | Fatcat ID | release_s66rmm7tqrdijk6lyubqnbod3i |
P698 | PubMed publication ID | 28967903 |
P50 | author | Anna Sablina | Q56769690 |
Veerle Janssens | Q42184056 | ||
P2093 | author name string | J Crowther | |
P Pauwels | |||
L Libbrecht | |||
X Sagaert | |||
C Lambrecht | |||
J V Louis | |||
W Sents | |||
Y Hoorne | |||
P2860 | cites work | B56-containing PP2A dephosphorylate ERK and their activity is controlled by the early gene IEX-1 and ERK | Q24303557 |
The tumor suppressor PP2A Abeta regulates the RalA GTPase | Q24307546 | ||
Identification of c-MYC as a target of the APC pathway | Q24310637 | ||
Identification of PP2A complexes and pathways involved in cell transformation | Q24316472 | ||
CIP2A inhibits PP2A in human malignancies | Q24319683 | ||
PME-1 protects extracellular signal-regulated kinase pathway activity from protein phosphatase 2A-mediated inactivation in human malignant glioma | Q24322118 | ||
Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation | Q24627354 | ||
TopHat: discovering splice junctions with RNA-Seq | Q24655505 | ||
Protein Phosphatase 2A as a Therapeutic Target in Acute Myeloid Leukemia | Q26752430 | ||
PPP2R5C Couples Hepatic Glucose and Lipid Homeostasis | Q27310235 | ||
edgeR: a Bioconductor package for differential expression analysis of digital gene expression data | Q27860819 | ||
The Sequence Alignment/Map format and SAMtools | Q27860966 | ||
Downregulation of PPP2R5E is a common event in acute myeloid leukemia that affects the oncogenic potential of leukemic cells | Q42583764 | ||
Protein phosphatase 2A regulatory subunit B56alpha associates with c-myc and negatively regulates c-myc accumulation | Q43240765 | ||
Consequences of widespread deregulation of the c-myc gene in transgenic mice: multiple neoplasms and normal development | Q43512505 | ||
New targets of beta-catenin signaling in the liver are involved in the glutamine metabolism | Q44226601 | ||
PP2A regulatory subunit PP2A-B' counteracts S6K phosphorylation. | Q47072710 | ||
PP2A Inactivation Mediated by PPP2R4 Haploinsufficiency Promotes Cancer Development | Q47632108 | ||
Upregulation of the oncoprotein SET determines poor clinical outcomes in hepatocellular carcinoma and shows therapeutic potential. | Q48064023 | ||
Gain of function of a p53 hot spot mutation in a mouse model of Li-Fraumeni syndrome. | Q52561781 | ||
CIP2A is highly expressed in hepatocellular carcinoma and predicts poor prognosis. | Q54298803 | ||
Cutadapt removes adapter sequences from high-throughput sequencing reads | Q55953584 | ||
Heterozygous Rb-1 delta 20/+mice are predisposed to tumors of the pituitary gland with a nearly complete penetrance | Q72306282 | ||
Low frequency of alterations of the alpha (PPP2R1A) and beta (PPP2R1B) isoforms of the subunit A of the serine-threonine phosphatase 2A in human neoplasms | Q73540311 | ||
Mutant p53 gain of function in two mouse models of Li-Fraumeni syndrome | Q81166001 | ||
Cancer-associated PP2A Aalpha subunits induce functional haploinsufficiency and tumorigenicity | Q81223136 | ||
Mutation of PPP2R1A: a new clue in unveiling the pathogenesis of uterine serous carcinoma | Q83698217 | ||
Lymphomas and leukemias in mice | Q83815801 | ||
The protein phosphatase 2A B56γ regulatory subunit is required for heart development | Q87098913 | ||
PME-1 modulates protein phosphatase 2A activity to promote the malignant phenotype of endometrial cancer cells | Q88079269 | ||
Creation of human tumour cells with defined genetic elements | Q28141602 | ||
Identification of specific PP2A complexes involved in human cell transformation | Q28248124 | ||
Alterations of the PPP2R1B gene in human lung and colon cancer | Q28284845 | ||
Regulation of beta-catenin signaling by the B56 subunit of protein phosphatase 2A | Q28609056 | ||
BEDTools: a flexible suite of utilities for comparing genomic features | Q29547332 | ||
The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups | Q29614700 | ||
Regulation of c-Myc Protein Abundance by a Protein Phosphatase 2A-Glycogen Synthase Kinase 3β-Negative Feedback Pathway | Q30464719 | ||
Mice lacking phosphatase PP2A subunit PR61/B'delta (Ppp2r5d) develop spatially restricted tauopathy by deregulation of CDK5 and GSK3beta | Q30473576 | ||
Phosphorylation by Cdk2 is required for Myc to repress Ras-induced senescence in cotransformation | Q33591386 | ||
Targeting c-MYC by antagonizing PP2A inhibitors in breast cancer | Q33835127 | ||
A B56gamma mutation in lung cancer disrupts the p53-dependent tumor-suppressor function of protein phosphatase 2A | Q33976501 | ||
Enumeration of the simian virus 40 early region elements necessary for human cell transformation | Q34117528 | ||
MYC inactivation uncovers pluripotent differentiation and tumour dormancy in hepatocellular cancer | Q34357796 | ||
MYC-dependent regulation and prognostic role of CIP2A in gastric cancer. | Q34983172 | ||
Human cancer-associated mutations in the Aα subunit of protein phosphatase 2A increase lung cancer incidence in Aα knock-in and knockout mice | Q35192607 | ||
iRegulon: from a gene list to a gene regulatory network using large motif and track collections | Q35212382 | ||
PP2A: the expected tumor suppressor | Q36015508 | ||
p27kip1 protein levels reflect a nexus of oncogenic signaling during cell transformation | Q36016730 | ||
Circumventing cellular control of PP2A by methylation promotes transformation in an Akt-dependent manner | Q36172723 | ||
Hepatocellular Carcinoma From Epidemiology to Prevention: Translating Knowledge into Practice | Q36199751 | ||
The B56γ3 regulatory subunit-containing protein phosphatase 2A outcompetes Akt to regulate p27KIP1 subcellular localization by selectively dephosphorylating phospho-Thr157 of p27KIP1. | Q36782507 | ||
Evaluation of PPP2R2A as a prostate cancer susceptibility gene: a comprehensive germline and somatic study | Q37044144 | ||
Central role of c-Myc during malignant conversion in human hepatocarcinogenesis | Q37186775 | ||
Protein phosphatase 2A: a target for anticancer therapy | Q38103646 | ||
Cancerous inhibitor of protein phosphatase 2A, an emerging human oncoprotein and a potential cancer therapy target. | Q38160825 | ||
Molecular profiling of liver tumors: classification and clinical translation for decision making | Q38264952 | ||
All roads lead to PP2A: exploiting the therapeutic potential of this phosphatase | Q38617799 | ||
Recurrent PPP2R1A Mutations in Uterine Cancer Act through a Dominant-Negative Mechanism to Promote Malignant Cell Growth. | Q38754146 | ||
Ser70 phosphorylation of Bcl-2 by selective tyrosine nitration of PP2A-B56δ stabilizes its antiapoptotic activity | Q38969632 | ||
B56γ tumor-associated mutations provide new mechanisms for B56γ-PP2A tumor suppressor activity | Q39145503 | ||
PPP2R2C loss promotes castration-resistance and is associated with increased prostate cancer-specific mortality | Q39181062 | ||
α4 is highly expressed in carcinogen-transformed human cells and primary human cancers | Q39588362 | ||
Genomic organisation, chromosomal localisation tissue distribution and developmental regulation of the PR61/B' regulatory subunits of protein phosphatase 2A in mice | Q40516271 | ||
A signalling pathway controlling c-Myc degradation that impacts oncogenic transformation of human cells | Q40572608 | ||
P433 | issue | 4 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 544-552 | |
P577 | publication date | 2017-10-02 | |
P1433 | published in | Oncogene | Q1568657 |
P1476 | title | Loss of protein phosphatase 2A regulatory subunit B56δ promotes spontaneous tumorigenesis in vivo | |
P478 | volume | 37 |
Q92864431 | PP2A: A Promising Biomarker and Therapeutic Target in Endometrial Cancer |
Q92740861 | PPM1G forms a PPP-type phosphatase holoenzyme with B56δ that maintains adherens junction integrity |
Q89781864 | PPP2R5D-Related Intellectual Disability and Neurodevelopmental Delay: A Review of the Current Understanding of the Genetics and Biochemical Basis of the Disorder |
Q57169683 | Targeted Therapies in Type II Endometrial Cancers: Too Little, but Not Too Late |
Q89835318 | The Cell Cycle Checkpoint System MAST(L)-ENSA/ARPP19-PP2A is Targeted by cAMP/PKA and cGMP/PKG in Anucleate Human Platelets |
Q54112403 | The impact of phosphatases on proliferative and survival signaling in cancer. |
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