| scholarly article | Q13442814 |
| P50 | author | Anna Sablina | Q56769690 |
| William C Hahn | Q88192808 | ||
| P2093 | author name string | Nathalie Colpaert | |
| Melissa Hector | |||
| P2860 | cites work | The Hallmarks of Cancer | Q221226 |
| Molecular cloning and mapping of the brain-abundant B1gamma subunit of protein phosphatase 2A, PPP2R2C, to human chromosome 4p16 | Q24290093 | ||
| PR72, a novel regulator of Wnt signaling required for Naked cuticle function | Q24293468 | ||
| Overexpression of the cis/trans isomerase PTPA triggers caspase 3-dependent apoptosis | Q24298793 | ||
| Structural and biochemical insights into the regulation of protein phosphatase 2A by small t antigen of SV40 | Q24307191 | ||
| The tumor suppressor PP2A Abeta regulates the RalA GTPase | Q24307546 | ||
| Protein phosphatase 2A subunit assembly: the catalytic subunit carboxy terminus is important for binding cellular B subunit but not polyomavirus middle tumor antigen | Q42797548 | ||
| Protein phosphatase 2A regulatory subunit B56alpha associates with c-myc and negatively regulates c-myc accumulation | Q43240765 | ||
| Protein phosphatase 2A PR130/B''alpha1 subunit binds to the SH2 domain-containing inositol polyphosphate 5-phosphatase 2 and prevents epidermal growth factor (EGF)-induced EGF receptor degradation sustaining EGF-mediated signaling. | Q54715563 | ||
| Risky immortalization by telomerase | Q59051302 | ||
| Human mammary epithelial cell transformation through the activation of phosphatidylinositol 3-kinase | Q73466868 | ||
| Low frequency of alterations of the alpha (PPP2R1A) and beta (PPP2R1B) isoforms of the subunit A of the serine-threonine phosphatase 2A in human neoplasms | Q73540311 | ||
| Functional expression of human PP2Ac in yeast permits the identification of novel C-terminal and dominant-negative mutant forms | Q78122298 | ||
| Cancer-associated PP2A Aalpha subunits induce functional haploinsufficiency and tumorigenicity | Q81223136 | ||
| PR130 is a modulator of the Wnt-signaling cascade that counters repression of the antagonist Naked cuticle | Q24310866 | ||
| Akt, a pleckstrin homology domain containing kinase, is activated primarily by phosphorylation | Q24312168 | ||
| PME-1 protects extracellular signal-regulated kinase pathway activity from protein phosphatase 2A-mediated inactivation in human malignant glioma | Q24322118 | ||
| Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC | Q24336321 | ||
| Alterations of the PPP2R1B gene located at 11q23 in human colorectal cancers | Q24669975 | ||
| Structural Basis of PP2A Inhibition by Small t Antigen | Q27646534 | ||
| Generation of active protein phosphatase 2A is coupled to holoenzyme assembly | Q27931554 | ||
| A novel and essential mechanism determining specificity and activity of protein phosphatase 2A (PP2A) in vivo. | Q27937987 | ||
| Creation of human tumour cells with defined genetic elements | Q28141602 | ||
| Alterations in protein phosphatase 2A subunit interaction in human carcinomas of the lung and colon with mutations in the A beta subunit gene | Q28213795 | ||
| alpha- and beta-forms of the 65-kDa subunit of protein phosphatase 2A have a similar 39 amino acid repeating structure | Q28238073 | ||
| Identification of specific PP2A complexes involved in human cell transformation | Q28248124 | ||
| Alterations of the PPP2R1B gene in human lung and colon cancer | Q28284845 | ||
| CDK8 is a colorectal cancer oncogene that regulates beta-catenin activity | Q28294122 | ||
| Delayed embryonic lethality in mice lacking protein phosphatase 2A catalytic subunit Calpha | Q28506401 | ||
| Regulation of beta-catenin signaling by the B56 subunit of protein phosphatase 2A | Q28609056 | ||
| Protein phosphatase 2A positively regulates Ras signaling by dephosphorylating KSR1 and Raf-1 on critical 14-3-3 binding sites | Q28609103 | ||
| Regulation of protein serine-threonine phosphatase type-2A by tyrosine phosphorylation | Q28638545 | ||
| A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen | Q29615061 | ||
| Integrative genomic approaches identify IKBKE as a breast cancer oncogene | Q33287979 | ||
| Actions of PP2A on the MAP kinase pathway and apoptosis are mediated by distinct regulatory subunits | Q34047058 | ||
| Enumeration of the simian virus 40 early region elements necessary for human cell transformation | Q34117528 | ||
| The interaction of SV40 small tumor antigen with protein phosphatase 2A stimulates the map kinase pathway and induces cell proliferation. | Q34345750 | ||
| Simian virus 40 small tumor antigen activates AKT and telomerase and induces anchorage-independent growth of human epithelial cells | Q34349115 | ||
| A tumor suppressor role for PP2A-B56alpha through negative regulation of c-Myc and other key oncoproteins | Q34609728 | ||
| Methylation of the protein phosphatase 2A catalytic subunit is essential for association of Balpha regulatory subunit but not SG2NA, striatin, or polyomavirus middle tumor antigen | Q34675213 | ||
| Human breast cancer cells generated by oncogenic transformation of primary mammary epithelial cells. | Q35076272 | ||
| Functional genetics and experimental models of human cancer | Q35830677 | ||
| The 3D structure of protein phosphatase 2A: new insights into a ubiquitous regulator of cell signaling | Q36741381 | ||
| Protein phosphatase 2A regulatory subunits and cancer. | Q37202956 | ||
| Identification of positively and negatively acting elements regulating expression of the E2F2 gene in response to cell growth signals | Q40023280 | ||
| Mutations which affect the inhibition of protein phosphatase 2A by simian virus 40 small-t antigen in vitro decrease viral transformation | Q40039575 | ||
| A signalling pathway controlling c-Myc degradation that impacts oncogenic transformation of human cells | Q40572608 | ||
| Critical role for SV40 small-t antigen in human cell transformation | Q40746221 | ||
| Ras enhances Myc protein stability. | Q40967066 | ||
| An inactive protein phosphatase 2A population is associated with methylesterase and can be re-activated by the phosphotyrosyl phosphatase activator | Q41775985 | ||
| P433 | issue | 24 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 10474-10484 | |
| P577 | publication date | 2010-12-01 | |
| P1433 | published in | Cancer Research | Q326097 |
| P1476 | title | Identification of PP2A complexes and pathways involved in cell transformation | |
| P478 | volume | 70 |
| Q40246228 | (DEAD)-box RNA helicase 3 modulates NF-κB signal pathway by controlling the phosphorylation of PP2A-C subunit |
| Q30405115 | A High-Efficiency Cellular Extraction System for Biological Proteomics |
| Q42322428 | Active β-catenin is regulated by the PTEN/PI3 kinase pathway: a role for protein phosphatase PP2A. |
| Q64134258 | Benzene-induced mouse hematotoxicity is regulated by a protein phosphatase 2A complex that stimulates transcription of |
| Q42500610 | CIP2A signature reveals the MYC dependency of CIP2A-regulated phenotypes and its clinical association with breast cancer subtypes |
| Q36814489 | Cancerous Inhibitor of PP2A Silencing Inhibits Proliferation and Promotes Apoptosis in Human Multiple Myeloma Cells |
| Q91713686 | Cancerous Inhibitor of Protein Phosphatase 2A as a Molecular Marker for Aggressiveness and Survival in Oral Squamous Cell Carcinoma |
| Q36172723 | Circumventing cellular control of PP2A by methylation promotes transformation in an Akt-dependent manner |
| Q27315944 | Circumventing embryonic lethality with Lcmt1 deficiency: generation of hypomorphic Lcmt1 mice with reduced protein phosphatase 2A methyltransferase expression and defects in insulin signaling |
| Q38335027 | Clinical significance of cancerous inhibitor of protein phosphatase 2A in human cancers |
| Q35101445 | Co-modulated behavior and effects of differentially expressed miRNA in colorectal cancer |
| Q37029660 | DNAJB6 chaperones PP2A mediated dephosphorylation of GSK3β to downregulate β-catenin transcription target, osteopontin |
| Q36192496 | Deletion of Pr130 Interrupts Cardiac Development in Zebrafish |
| Q41913139 | Deregulation of the phosphatase, PP2A is a common event in breast cancer, predicting sensitivity to FTY720. |
| Q38904928 | Deregulation of the protein phosphatase 2A, PP2A in cancer: complexity and therapeutic options. |
| Q42583764 | Downregulation of PPP2R5E is a common event in acute myeloid leukemia that affects the oncogenic potential of leukemic cells |
| Q102152168 | EZH2-mediated PP2A inactivation confers resistance to HER2-targeted breast cancer therapy |
| Q47571869 | Functional importance of PP2A regulatory subunit loss in breast cancer |
| Q50317222 | HDAC1 and HDAC2 integrate checkpoint kinase phosphorylation and cell fate through the phosphatase-2A subunit PR130. |
| Q31059965 | Identification and functional analysis of variant haplotypes in the 5'-flanking region of protein phosphatase 2A-Bδ gene |
| Q58374470 | Identification of PP2A/Set Binding Sites and Design of Interacting Peptides with Potential Clinical Applications |
| Q39062088 | Identification of the adenovirus E4orf4 protein binding site on the B55α and Cdc55 regulatory subunits of PP2A: Implications for PP2A function, tumor cell killing and viral replication |
| Q34123850 | Impaired CK1 delta activity attenuates SV40-induced cellular transformation in vitro and mouse mammary carcinogenesis in vivo |
| Q36959063 | Impaired expression of protein phosphatase 2A subunits enhances metastatic potential of human prostate cancer cells through activation of AKT pathway. |
| Q49791664 | In vivo pieces of the PP2A onco-puzzle fallen into place |
| Q90197696 | Inactivation of PP2A by a recurrent mutation drives resistance to MEK inhibitors |
| Q36275673 | Inhibition of Pten deficient Castration Resistant Prostate Cancer by Targeting of the SET - PP2A Signaling axis |
| Q38737146 | Inhibition of protein methylesterase 1 decreased cancerous phenotypes in endometrial adenocarcinoma cell lines and xenograft tumor models |
| Q36273561 | Label-free quantitative phosphoproteomics with novel pairwise abundance normalization reveals synergistic RAS and CIP2A signaling. |
| Q38891984 | Leucine-rich repeat-containing protein 59 mediates nuclear import of cancerous inhibitor of PP2A in prostate cancer cells |
| Q34133391 | Loss of breast epithelial marker hCLCA2 promotes epithelial-to-mesenchymal transition and indicates higher risk of metastasis |
| Q47716673 | Loss of protein phosphatase 2A regulatory subunit B56δ promotes spontaneous tumorigenesis in vivo. |
| Q34443783 | Malawi polyomavirus is a prevalent human virus that interacts with known tumor suppressors |
| Q40526722 | Merkel cell polyomavirus large T antigen has growth-promoting and inhibitory activities |
| Q52714356 | MicroRNA-652 induces NED in LNCaP and EMT in PC3 prostate cancer cells. |
| Q92490663 | Mission Possible: Advances in MYC Therapeutic Targeting in Cancer |
| Q39218657 | NNMT Silencing Activates Tumor Suppressor PP2A, Inactivates Oncogenic STKs, and Inhibits Tumor Forming Ability. |
| Q38613399 | OP449 inhibits breast cancer growth without adverse metabolic effects |
| Q42152408 | Oncoprotein CIP2A is stabilized via interaction with tumor suppressor PP2A/B56. |
| Q38886150 | PHD2 Targeting Overcomes Breast Cancer Cell Death upon Glucose Starvation in a PP2A/B55α-Mediated Manner |
| Q36796453 | PP2A Counterbalances Phosphorylation of pRB and Mitotic Proteins by Multiple CDKs: Potential Implications for PP2A Disruption in Cancer |
| Q39369307 | PP2A inactivation is a crucial step in triggering apoptin-induced tumor-selective cell killing |
| Q26830813 | PP2A targeting by viral proteins: a widespread biological strategy from DNA/RNA tumor viruses to HIV-1 |
| Q35541658 | PP2A-B56α controls oncogene-induced senescence in normal and tumor human melanocytic cells |
| Q33985022 | PP2A-mediated regulation of Ras signaling in G2 is essential for stable quiescence and normal G1 length |
| Q92864431 | PP2A: A Promising Biomarker and Therapeutic Target in Endometrial Cancer |
| Q39181062 | PPP2R2C loss promotes castration-resistance and is associated with increased prostate cancer-specific mortality |
| Q90974926 | PR55α regulatory subunit of PP2A inhibits the MOB1/LATS cascade and activates YAP in pancreatic cancer cells |
| Q35970084 | Peroxisome proliferator-activated receptor γ decouples fatty acid uptake from lipid inhibition of insulin signaling in skeletal muscle |
| Q37524180 | Phenothiazines induce PP2A-mediated apoptosis in T cell acute lymphoblastic leukemia. |
| Q33890604 | Phorbol esters in seed oil of Jatropha curcas L. (saboodam in Thai) and their association with cancer prevention: from the initial investigation to the present topics |
| Q35504084 | Phosphatases: the new brakes for cancer development? |
| Q33686351 | Protein Phosphatase 2A (PP2A) Regulates EG5 to Control Mitotic Progression |
| Q26752430 | Protein Phosphatase 2A as a Therapeutic Target in Acute Myeloid Leukemia |
| Q40756895 | Protein phosphatase 2A (PP2A) regulates low density lipoprotein uptake through regulating sterol response element-binding protein-2 (SREBP-2) DNA binding |
| Q91843539 | Protein phosphatase 2A Aα regulates Aβ protein expression and stability |
| Q38953688 | Protein phosphatase 2A is essential to maintain active Wnt signaling and its Aβ tumor suppressor subunit is not expressed in colon cancer cells |
| Q92457809 | Protein phosphatase 2A modulates podocyte maturation and glomerular functional integrity in mice |
| Q38103646 | Protein phosphatase 2A: a target for anticancer therapy |
| Q35640940 | Restricted protein phosphatase 2A targeting by Merkel cell polyomavirus small T antigen |
| Q35943461 | Retroviral cyclin enhances cyclin-dependent kinase-8 activity |
| Q38648429 | Role of "oncogenic nexus" of CIP2A in breast oncogenesis: how does it work? |
| Q34651583 | Role of a novel functional variant in the PPP2R1A promoter on the regulation of PP2A-Aalpha and the risk of hepatocellular carcinoma |
| Q92932427 | Role of protein phosphatases PP1, PP2A, PP4 and Cdc14 in the DNA damage response |
| Q92490373 | STRIPAK directs PP2A activity toward MAP4K4 to promote oncogenic transformation of human cells |
| Q36012977 | Signalling by protein phosphatases and drug development: a systems-centred view. |
| Q27684630 | Structural and biochemical characterization of human PR70 in isolation and in complex with the scaffolding subunit of protein phosphatase 2A |
| Q27680173 | Structural basis of PP2A activation by PTPA, an ATP-dependent activation chaperone |
| Q27678559 | Structure of the Ca2+-dependent PP2A heterotrimer and insights into Cdc6 dephosphorylation |
| Q28732118 | TBC1D3, a hominoid-specific gene, delays IRS-1 degradation and promotes insulin signaling by modulating p70 S6 kinase activity |
| Q89500713 | Targeting PP2A inhibits the growth of triple-negative breast cancer cells |
| Q33835127 | Targeting c-MYC by antagonizing PP2A inhibitors in breast cancer |
| Q28546976 | The Human Adenovirus Type 5 E4orf4 Protein Targets Two Phosphatase Regulators of the Hippo Signaling Pathway |
| Q89944283 | The Role of MYC and PP2A in the Initiation and Progression of Myeloid Leukemias |
| Q42102304 | The association between Salt-inducible kinase 2 (SIK2) and gamma isoform of the regulatory subunit B55 of PP2A (B55gamma) contributes to the survival of glioma cells under glucose depletion through inhibiting the phosphorylation of S6K. |
| Q26824764 | The biogenesis of active protein phosphatase 2A holoenzymes: a tightly regulated process creating phosphatase specificity |
| Q26739246 | The broken "Off" switch in cancer signaling: PP2A as a regulator of tumorigenesis, drug resistance, and immune surveillance |
| Q34775279 | The tumor suppressor CDKN3 controls mitosis |
| Q47137224 | The tumor suppressor phosphatase PP2A-B56α regulates stemness and promotes the initiation of malignancies in a novel murine model |
| Q35146774 | Viewing serine/threonine protein phosphatases through the eyes of drug designers |
| Q53277017 | [Targeting of PP2A enzymes by viral proteins and cancer signalling]. |
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