Deletion of endoplasmic reticulum stress-responsive co-chaperone p58IPK protects mice from diet-induced steatohepatitis.

scientific article

Deletion of endoplasmic reticulum stress-responsive co-chaperone p58IPK protects mice from diet-induced steatohepatitis. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1111/HEPR.13052
P932PMC publication ID5932231
P698PubMed publication ID29316085

P50authorRondell P GrahamQ48088845
P2093author name stringHarmeet Malhi
Petra Hirsova
Barbora Nozickova
Debanjali Dasgupta
Amy S Mauer
Harikrishna Bandla
Swarup Kumar
P2860cites workp58IPK is an inhibitor of the eIF2α kinase GCN2 and its localization and expression underpin protein synthesis and ER processing capacityQ24306090
Cloning, expression, and cellular localization of the oncogenic 58-kDa inhibitor of the RNA-activated human and mouse protein kinaseQ24322603
Control of PERK eIF2alpha kinase activity by the endoplasmic reticulum stress-induced molecular chaperone P58IPK.Q24541469
Divergent effects of PERK and IRE1 signaling on cell viabilityQ27438124
Signal integration in the endoplasmic reticulum unfolded protein responseQ27860577
Nonalcoholic fatty liver disease: a systematic reviewQ28263139
Regulation of hepatic lipogenesis by the transcription factor XBP1Q28507784
Double-stranded RNA-dependent protein kinase links pathogen sensing with stress and metabolic homeostasisQ28510028
Diabetes mellitus and exocrine pancreatic dysfunction in perk-/- mice reveals a role for translational control in secretory cell survivalQ28593963
Double-stranded RNA-independent dimerization of interferon-induced protein kinase PKR and inhibition of dimerization by the cellular P58IPK inhibitorQ33786424
Saturated fatty acid induction of endoplasmic reticulum stress and apoptosis in human liver cells via the PERK/ATF4/CHOP signaling pathwayQ34128069
P58IPK, a novel endoplasmic reticulum stress-inducible protein and potential negative regulator of eIF2alpha signalingQ34179244
Absence of BiP co-chaperone DNAJC3 causes diabetes mellitus and multisystemic neurodegenerationQ34451639
Nonalcoholic fatty liver disease (NAFLD) activity score and the histopathologic diagnosis in NAFLD: distinct clinicopathologic meaningsQ34815796
Energy expenditure in children with type I diabetes: evidence for increased thermogenesisQ35715277
The role of p58IPK in protecting the stressed endoplasmic reticulumQ35949048
Membrane lipid saturation activates endoplasmic reticulum unfolded protein response transducers through their transmembrane domainsQ36712468
C/EBP homologous protein-induced macrophage apoptosis protects mice from steatohepatitisQ36967242
Lipotoxic lethal and sublethal stress signaling in hepatocytes: relevance to NASH pathogenesis.Q38799232
Hepatic deletion of X-box binding protein 1 impairs bile acid metabolism in miceQ39048675
Inhibition of sphingosine 1-phosphate signaling ameliorates murine nonalcoholic steatohepatitisQ39049164
The unfolded protein response is activated in skeletal muscle by high-fat feeding: potential role in the downregulation of protein synthesisQ39700372
TRAIL receptor deletion in mice suppresses the inflammation of nutrient excessQ39817074
Many commercially available antibodies for detection of CHOP expression as a marker of endoplasmic reticulum stress fail specificity evaluation.Q39957900
Liver-specific loss of glucose-regulated protein 78 perturbs the unfolded protein response and exacerbates a spectrum of liver diseases in miceQ41825121
Characterization of distinct subpopulations of hepatic macrophages in HFD/obese miceQ42688383
Resting energy expenditure in type 2 diabetic patients and the effect of insulin bolus.Q51314244
Comparison of energy metabolism in insulin-dependent and non-insulin-dependent diabetes mellitus.Q51573860
Pancreatic beta-cell failure and diabetes in mice with a deletion mutation of the endoplasmic reticulum molecular chaperone gene P58IPKQ55847305
Hepatocyte apoptosis and fas expression are prominent features of human nonalcoholic steatohepatitisQ73735584
P4510describes a project that usesImageJQ1659584
P433issue6
P921main subjectsteatohepatitisQ2335423
endoplasmic reticulumQ79927
molecular chaperonesQ422496
P1104number of pages16
P304page(s)479-494
P577publication date2018-02-09
P1433published inHepatology ResearchQ15752035
P1476titleDeletion of endoplasmic reticulum stress-responsive co-chaperone p58IPK protects mice from diet-induced steatohepatitis
P478volume48

Reverse relations

cites work (P2860)
Q60947050Hepatocyte-Derived Lipotoxic Extracellular Vesicle Sphingosine 1-Phosphate Induces Macrophage Chemotaxis
Q92370692Inhibiting alpha subunit of eukaryotic initiation factor 2 dephosphorylation protects injured hepatocytes and reduces hepatocyte proliferation in acute liver injury

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