scholarly article | Q13442814 |
P356 | DOI | 10.4049/JIMMUNOL.1701085 |
P698 | PubMed publication ID | 28947542 |
P50 | author | Troy A Baldwin | Q64515004 |
Alexander Y W Suen | Q95951821 | ||
P2093 | author name string | Laura M Henao Caviedes | |
Qian Nancy Hu | |||
P2860 | cites work | BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes | Q28203083 |
Aire regulates negative selection of organ-specific T cells | Q28213185 | ||
Central tolerance: learning self-control in the thymus | Q28275215 | ||
Transcriptional activation of known and novel apoptotic pathways by Nur77 orphan steroid receptor | Q28512848 | ||
Functional redundancy of the Nur77 and Nor-1 orphan steroid receptors in T-cell apoptosis | Q28591401 | ||
T cell receptor antagonist peptides induce positive selection | Q29618820 | ||
A novel TCR transgenic model reveals that negative selection involves an immediate, Bim-dependent pathway and a delayed, Bim-independent pathway | Q33523813 | ||
T cell-specific inhibition of multiple apoptotic pathways blocks negative selection and causes autoimmunity | Q34228163 | ||
Regulation of macrophage inflammatory gene expression by the orphan nuclear receptor Nur77. | Q34474472 | ||
The self-obsession of T cells: how TCR signaling thresholds affect fate 'decisions' and effector function | Q35143413 | ||
Defects in the Bcl-2-regulated apoptotic pathway lead to preferential increase of CD25 low Foxp3+ anergic CD4+ T cells | Q35147708 | ||
T cell receptor signal strength in Treg and iNKT cell development demonstrated by a novel fluorescent reporter mouse | Q35213550 | ||
Arthritogenic self-reactive CD4+ T cells acquire an FR4hiCD73hi anergic state in the presence of Foxp3+ regulatory T cells | Q35629308 | ||
Impairment of organ-specific T cell negative selection by diabetes susceptibility genes: genomic analysis by mRNA profiling | Q35724760 | ||
Proapoptotic protein Bim is differentially required during thymic clonal deletion to ubiquitous versus tissue-restricted antigens | Q35735244 | ||
Deficiency of Nuclear Receptor Nur77 Aggravates Mouse Experimental Colitis by Increased NFκB Activity in Macrophages | Q35737476 | ||
Nuclear receptor Nr4a1 modulates both regulatory T-cell (Treg) differentiation and clonal deletion | Q35845038 | ||
Clonal deletion and the fate of autoreactive thymocytes that survive negative selection | Q35996079 | ||
A broad range of self-reactivity drives thymic regulatory T cell selection to limit responses to self. | Q36275699 | ||
Reduced TCR signaling potential impairs negative selection but does not result in autoimmune disease | Q36278062 | ||
Inhibition of Nur77/Nurr1 leads to inefficient clonal deletion of self-reactive T cells | Q36366355 | ||
Constitutive class I-restricted exogenous presentation of self antigens in vivo | Q36367249 | ||
Central tolerance to tissue-specific antigens mediated by direct and indirect antigen presentation | Q36399298 | ||
The BH3-only proteins Bim and Puma cooperate to impose deletional tolerance of organ-specific antigens | Q36406557 | ||
CD4(+) T cell anergy prevents autoimmunity and generates regulatory T cell precursors | Q36586349 | ||
Helios marks strongly autoreactive CD4+ T cells in two major waves of thymic deletion distinguished by induction of PD-1 or NF-κB. | Q36603522 | ||
The genetic landscape of type 2 diabetes in mice | Q36612875 | ||
During negative selection, Nur77 family proteins translocate to mitochondria where they associate with Bcl-2 and expose its proapoptotic BH3 domain | Q36639961 | ||
Murine thymic selection quantified using a unique method to capture deleted T cells | Q36712531 | ||
Distinct transcriptional programs in thymocytes responding to T cell receptor, Notch, and positive selection signals. | Q37415532 | ||
Selection of regulatory T cells in the thymus | Q37982939 | ||
Apoptotic signals delivered through the T-cell receptor of a T-cell hybrid require the immediate-early gene nur77. | Q38311983 | ||
Development of T-cell tolerance utilizes both cell-autonomous and cooperative presentation of self-antigen | Q38810900 | ||
Are Regulatory T Cells Defective in Type 1 Diabetes and Can We Fix Them? | Q38999162 | ||
Nuclear receptor Nur77 suppresses inflammatory response dependent on COX-2 in macrophages induced by oxLDL. | Q39716580 | ||
Tonic LAT-HDAC7 Signals Sustain Nur77 and Irf4 Expression to Tune Naive CD4 T Cells | Q40188158 | ||
Differential roles for Bim and Nur77 in thymocyte clonal deletion induced by ubiquitous self-antigen | Q41424665 | ||
NR4A1 (Nur77) deletion polarizes macrophages toward an inflammatory phenotype and increases atherosclerosis | Q42573987 | ||
Islet beta-cell-specific T cells can use different homing mechanisms to infiltrate and destroy pancreatic islets | Q43030055 | ||
A role for the orphan steroid receptor Nur77 in apoptosis accompanying antigen-induced negative selection | Q44593628 | ||
Requirement for the orphan steroid receptor Nur77 in apoptosis of T-cell hybridomas | Q46064858 | ||
Gene expression analysis of thymocyte selection in vivo | Q47620555 | ||
Characterization of transcriptional regulation during negative selection in vivo | Q47777685 | ||
Nr4a receptors are essential for thymic regulatory T cell development and immune homeostasis. | Q50764082 | ||
Bim-mediated apoptosis is not necessary for thymic negative selection to ubiquitous self-antigens. | Q54578300 | ||
Fezf2 Orchestrates a Thymic Program of Self-Antigen Expression for Immune Tolerance. | Q55059402 | ||
P433 | issue | 9 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 3147-3157 | |
P577 | publication date | 2017-09-25 | |
P1433 | published in | Journal of Immunology | Q3521441 |
P1476 | title | Nur77 Regulates Nondeletional Mechanisms of Tolerance in T Cells | |
P478 | volume | 199 |
Q100670731 | 'Nur'turing tumor T cell tolerance and exhaustion: novel function for Nuclear Receptor Nur77 in immunity |
Q90131913 | Glucocorticoids Oppose Thymocyte Negative Selection by Inhibiting Helios and Nur77 |
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