scholarly article | Q13442814 |
P2093 | author name string | Yisang Yoon | |
Sylvia B Smith | |||
Hakjoo Lee | |||
P2860 | cites work | OPA1, encoding a dynamin-related GTPase, is mutated in autosomal dominant optic atrophy linked to chromosome 3q28 | Q24290356 |
Dynamin-related protein Drp1 is required for mitochondrial division in mammalian cells | Q24291591 | ||
Primary structure of a dynamin-related mouse mitochondrial GTPase and its distribution in brain, subcellular localization, and effect on mitochondrial morphology | Q24292310 | ||
Inducible proteolytic inactivation of OPA1 mediated by the OMA1 protease in mammalian cells | Q24293452 | ||
Export of mitochondrial AIF in response to proapoptotic stimuli depends on processing at the intermembrane space | Q24298363 | ||
YME1L controls the accumulation of respiratory chain subunits and is required for apoptotic resistance, cristae morphogenesis, and cell proliferation | Q24302280 | ||
OPA1 cleavage depends on decreased mitochondrial ATP level and bivalent metals | Q81161420 | ||
OPA1 mutations induce mitochondrial DNA instability and optic atrophy 'plus' phenotypes | Q24304868 | ||
Mitochondrial functions and estrogen receptor-dependent nuclear translocation of pleiotropic human prohibitin 2 | Q24305114 | ||
C11orf83, a mitochondrial cardiolipin-binding protein involved in bc1 complex assembly and supercomplex stabilization | Q24315727 | ||
Loss of OPA1 perturbates the mitochondrial inner membrane structure and integrity, leading to cytochrome c release and apoptosis | Q24338169 | ||
OPA1 requires mitofusin 1 to promote mitochondrial fusion | Q24560014 | ||
Multi-system neurological disease is common in patients with OPA1 mutations | Q24619312 | ||
Prohibitin 2: At a communications crossroads | Q26825374 | ||
Decreasing mitochondrial fission diminishes vascular smooth muscle cell migration and ameliorates intimal hyperplasia | Q27302132 | ||
Oma1, a novel membrane-bound metallopeptidase in mitochondria with activities overlapping with the m-AAA protease | Q27931615 | ||
Prohibitins act as a membrane-bound chaperone for the stabilization of mitochondrial proteins. | Q27934000 | ||
Prohibitins regulate membrane protein degradation by the m-AAA protease in mitochondria | Q27934696 | ||
Mitochondrial inner-membrane fusion and crista maintenance requires the dynamin-related GTPase Mgm1. | Q27936009 | ||
Multifaceted role of prohibitin in cell survival and apoptosis | Q28087391 | ||
Nuclear gene OPA1, encoding a mitochondrial dynamin-related protein, is mutated in dominant optic atrophy | Q28140286 | ||
The human dynamin-related protein OPA1 is anchored to the mitochondrial inner membrane facing the inter-membrane space | Q28215023 | ||
Mutation spectrum and splicing variants in the OPA1 gene | Q28216607 | ||
Dynamin-like protein 1 is involved in peroxisomal fission | Q28218956 | ||
The i-AAA protease YME1L and OMA1 cleave OPA1 to balance mitochondrial fusion and fission | Q28235694 | ||
The Prohibitins: emerging roles in diverse functions | Q28248077 | ||
OPA1-dependent cristae modulation is essential for cellular adaptation to metabolic demand | Q28249429 | ||
OPA1 controls apoptotic cristae remodeling independently from mitochondrial fusion | Q28251846 | ||
The OPA1-dependent mitochondrial cristae remodeling pathway controls atrophic, apoptotic, and ischemic tissue damage | Q28262786 | ||
Blue native PAGE | Q28296330 | ||
Regulation of mitochondrial morphology through proteolytic cleavage of OPA1 | Q28571639 | ||
Regulation of OPA1 processing and mitochondrial fusion by m-AAA protease isoenzymes and OMA1 | Q28594164 | ||
SLP-2 is required for stress-induced mitochondrial hyperfusion | Q28594182 | ||
Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development | Q28594513 | ||
Disruption of fusion results in mitochondrial heterogeneity and dysfunction | Q29616566 | ||
During autophagy mitochondria elongate, are spared from degradation and sustain cell viability. | Q29616569 | ||
Opa1-mediated cristae opening is Bax/Bak and BH3 dependent, required for apoptosis, and independent of Bak oligomerization | Q30485835 | ||
Mitofusins and OPA1 mediate sequential steps in mitochondrial membrane fusion | Q30489225 | ||
Mitochondrial 'kiss-and-run': interplay between mitochondrial motility and fusion-fission dynamics | Q30491358 | ||
OPA1 disease alleles causing dominant optic atrophy have defects in cardiolipin-stimulated GTP hydrolysis and membrane tubulation | Q30494366 | ||
Loss of OPA1 disturbs cellular calcium homeostasis and sensitizes for excitotoxicity | Q30532888 | ||
Impaired OMA1-dependent cleavage of OPA1 and reduced DRP1 fission activity combine to prevent mitophagy in cells that are dependent on oxidative phosphorylation | Q30578089 | ||
Proteolytic cleavage of Opa1 stimulates mitochondrial inner membrane fusion and couples fusion to oxidative phosphorylation | Q33599185 | ||
Mitochondrial fusion is required for mtDNA stability in skeletal muscle and tolerance of mtDNA mutations | Q33877979 | ||
Mammalian dynamin-like protein DLP1 tubulates membranes | Q33946794 | ||
AAA proteases of mitochondria: quality control of membrane proteins and regulatory functions during mitochondrial biogenesis | Q34332387 | ||
Increased production of reactive oxygen species in hyperglycemic conditions requires dynamic change of mitochondrial morphology | Q34479807 | ||
Mitochondrial dynamics in diabetes | Q34511749 | ||
A Mitofusin-2-dependent inactivating cleavage of Opa1 links changes in mitochondria cristae and ER contacts in the postprandial liver. | Q34526585 | ||
Mitochondrial threshold effects. | Q35017647 | ||
Tubular network formation protects mitochondria from autophagosomal degradation during nutrient starvation | Q35064216 | ||
The dynamin-related GTPase Opa1 is required for glucose-stimulated ATP production in pancreatic beta cells | Q35083432 | ||
Nutrient-sensitized screening for drugs that shift energy metabolism from mitochondrial respiration to glycolysis | Q35101307 | ||
Opa1 overexpression ameliorates the phenotype of two mitochondrial disease mouse models. | Q35689631 | ||
Mitochondrial fission triggered by hyperglycemia is mediated by ROCK1 activation in podocytes and endothelial cells | Q35754670 | ||
Selective Oma1 protease-mediated proteolysis of Cox1 subunit of cytochrome oxidase in assembly mutants | Q35801928 | ||
Mitochondrial diseases and ATPase defects of nuclear origin. | Q35849777 | ||
Mitochondrial complex I plays an essential role in human respirasome assembly | Q35868845 | ||
Fine-tuning of Drp1/Fis1 availability by AKAP121/Siah2 regulates mitochondrial adaptation to hypoxia | Q35990125 | ||
Perspectives on: SGP symposium on mitochondrial physiology and medicine: what comes first, misshape or dysfunction? The view from metabolic excess | Q35995740 | ||
Metalloprotease OMA1 Fine-tunes Mitochondrial Bioenergetic Function and Respiratory Supercomplex Stability | Q36056367 | ||
Regulation of mitochondrial dynamics: another process modulated by Ca2+ signals? | Q36102553 | ||
OPA1 processing controls mitochondrial fusion and is regulated by mRNA splicing, membrane potential, and Yme1L. | Q36119045 | ||
Regulation of the mitochondrial dynamin-like protein Opa1 by proteolytic cleavage | Q36119051 | ||
Prohibitins control cell proliferation and apoptosis by regulating OPA1-dependent cristae morphogenesis in mitochondria | Q36453541 | ||
Mitochondrial cristae shape determines respiratory chain supercomplexes assembly and respiratory efficiency | Q37215027 | ||
Stress-regulated translational attenuation adapts mitochondrial protein import through Tim17A degradation. | Q37524374 | ||
Prohibitins and the functional compartmentalization of mitochondrial membranes. | Q37627477 | ||
Mito-Morphosis: Mitochondrial Fusion, Fission, and Cristae Remodeling as Key Mediators of Cellular Function | Q38669205 | ||
Cell survival during complete nutrient deprivation depends on lipid droplet-fueled β-oxidation of fatty acids | Q39111042 | ||
Respiratory active mitochondrial supercomplexes. | Q39913363 | ||
Structural basis of mitochondrial tethering by mitofusin complexes. | Q40527845 | ||
Loss of the intermembrane space protein Mgm1/OPA1 induces swelling and localized constrictions along the lengths of mitochondria | Q44768454 | ||
OPA1 functionally interacts with MIC60 but is dispensable for crista junction formation. | Q51537419 | ||
Threshold effect and tissue specificity. Implication for mitochondrial cytopathies | Q73176064 | ||
OPA1 alternate splicing uncouples an evolutionary conserved function in mitochondrial fusion from a vertebrate restricted function in apoptosis | Q79196601 | ||
P433 | issue | 17 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 7115-7130 | |
P577 | publication date | 2017-03-15 | |
P1433 | published in | Journal of Biological Chemistry | Q867727 |
P1476 | title | The short variant of the mitochondrial dynamin OPA1 maintains mitochondrial energetics and cristae structure | |
P478 | volume | 292 |
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Q98943954 | Concurrent OPA1 mutation and chromosome 3q deletion leading to Behr syndrome: a case report |
Q93048229 | Diabetic Pregnancy and Maternal High-Fat Diet Impair Mitochondrial Dynamism in the Developing Fetal Rat Heart by Sex-Specific Mechanisms |
Q90265129 | Dysregulated Mitochondrial Dynamics and Metabolism in Obesity, Diabetes, and Cancer |
Q64086905 | Enhanced autophagic-lysosomal activity and increased BAG3-mediated selective macroautophagy as adaptive response of neuronal cells to chronic oxidative stress |
Q47216990 | Exercise and Mitochondrial Dynamics: Keeping in Shape with ROS and AMPK. |
Q93103041 | Functional Interplay between Cristae Biogenesis, Mitochondrial Dynamics and Mitochondrial DNA Integrity |
Q92277670 | Hydrogen sulfide attenuates mitochondrial dysfunction-induced cellular senescence and apoptosis in alveolar epithelial cells by upregulating sirtuin 1 |
Q90709145 | Interplay of mitochondrial fission-fusion with cell cycle regulation: Possible impacts on stem cell and organismal aging |
Q47316049 | Laminar Shear Stress Promotes Mitochondrial Homeostasis in Endothelial Cells. |
Q50115832 | Loss of mitochondrial protease ClpP protects mice from diet-induced obesity and insulin resistance. |
Q58616126 | Loss of the mitochondrial -AAA protease YME1L leads to ocular dysfunction and spinal axonopathy |
Q60919648 | Melatonin Attenuates Cardiac Reperfusion Stress by Improving OPA1-Related Mitochondrial Fusion in a Yap-Hippo Pathway-Dependent Manner |
Q89466157 | MitoQ regulates redox-related noncoding RNAs to preserve mitochondrial network integrity in pressure-overload heart failure |
Q96303473 | Mitochondrial Bioenergetics and Dynamics in Secretion Processes |
Q92327164 | Mitochondrial Dynamics of Proximal Tubular Epithelial Cells in Nephropathic Cystinosis |
Q41056420 | Mitochondrial Heterogeneity: Evaluating Mitochondrial Subpopulation Dynamics in Stem Cells. |
Q92296866 | Mitochondrial Integrity Regulated by Lipid Metabolism Is a Cell-Intrinsic Checkpoint for Treg Suppressive Function |
Q60907654 | Mitochondrial Membrane Dynamics-Functional Positioning of OPA1 |
Q48015636 | Mitochondrial dynamics: The dynamin superfamily and execution by collusion |
Q92562059 | Mitochondrial fusion is required for regulation of mitochondrial DNA replication |
Q90053785 | Mitochondrial stress is relayed to the cytosol by an OMA1-DELE1-HRI pathway |
Q90261718 | OPA1 overexpression ameliorates mitochondrial cristae remodeling, mitochondrial dysfunction, and neuronal apoptosis in prion diseases |
Q47770905 | Regulation of mitochondrial bioenergetics by the non-canonical roles of mitochondrial dynamics proteins in the heart |
Q91776836 | Structure and assembly of the mitochondrial membrane remodelling GTPase Mgm1 |
Q89900069 | The anti-viral dynamin family member MxB participates in mitochondrial integrity |
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