Phosphatidylinositol 3-kinase regulates bone morphogenetic protein-2 (BMP-2)-induced myocyte enhancer factor 2A-dependent transcription of BMP-2 gene in cardiomyocyte precursor cells.

scientific article published on 27 March 2003

Phosphatidylinositol 3-kinase regulates bone morphogenetic protein-2 (BMP-2)-induced myocyte enhancer factor 2A-dependent transcription of BMP-2 gene in cardiomyocyte precursor cells. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M302277200
P698PubMed publication ID12663654

P50authorLenin MahimainathanQ73188780
P2093author name stringNandini Ghosh-Choudhury
Bysani Chandrasekar
Goutam Ghosh Choudhury
Sherry L Abboud
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Overlapping and differential localization of Bmp-2, Bmp-4, Msx-2 and apoptosis in the endocardial cushion and adjacent tissues of the developing mouse heart.Q52130785
BMP2 is required for early heart development during a distinct time period.Q52170375
Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factorQ22009126
Smad proteins function as co-modulators for MEF2 transcriptional regulatory proteinsQ24290752
The Spemann organizer signal noggin binds and inactivates bone morphogenetic protein 4Q24315313
Bone morphogenetic proteins induce cardiomyocyte differentiation through the mitogen-activated protein kinase kinase kinase TAK1 and cardiac transcription factors Csx/Nkx-2.5 and GATA-4Q24554412
Structural basis of BMP signalling inhibition by the cystine knot protein NogginQ27640149
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Structure and expression of Xenopus tropicalis BMP-2 and BMP-4 genesQ28202156
MEF2: a calcium-dependent regulator of cell division, differentiation and deathQ28215798
Signalling through the lipid products of phosphoinositide-3-OH kinaseQ28241516
Noggin, cartilage morphogenesis, and joint formation in the mammalian skeletonQ28272018
Transcriptional control of muscle development by myocyte enhancer factor-2 (MEF2) proteinsQ28294155
MEF2B is a potent transactivator expressed in early myogenic lineagesQ28505977
Bone morphogenetic protein-2 inhibits serum deprivation-induced apoptosis of neonatal cardiac myocytes through activation of the Smad1 pathwayQ28567170
Myocyte enhancer factor (MEF) 2C: a tissue-restricted member of the MEF-2 family of transcription factorsQ28588872
Control of mouse cardiac morphogenesis and myogenesis by transcription factor MEF2CQ28589290
Bone morphogenetic proteins: multifunctional regulators of vertebrate developmentQ29618986
Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt.Q30452681
Multiple pathways control protein kinase C phosphorylationQ33838086
An essential role of phosphatidylinositol 3-kinase in myogenic differentiation.Q36730708
Association and direct activation of signal transducer and activator of transcription1alpha by platelet-derived growth factor receptorQ37383530
Increased effect of interferon gamma on PDGF-induced c-fos gene transcription in glomerular mesangial cells: differential effect of the transcriptional coactivator CBP on STAT1alpha activationQ38310580
Post-translational control of the MEF2A transcriptional regulatory proteinQ39728215
Regulation of Muscle Differentiation by the MEF2 Family of MADS Box Transcription FactorsQ40432858
Requirement of BMP-2-induced phosphatidylinositol 3-kinase and Akt serine/threonine kinase in osteoblast differentiation and Smad-dependent BMP-2 gene transcription.Q40722201
The insulin-like growth factor-phosphatidylinositol 3-kinase-Akt signaling pathway regulates myogenin expression in normal myogenic cells but not in rhabdomyosarcoma-derived RD cellsQ40749592
BMP signaling regulates Nkx2-5 activity during cardiomyogenesisQ40765157
Bone morphogenetic protein-2 induces cyclin kinase inhibitor p21 and hypophosphorylation of retinoblastoma protein in estradiol-treated MCF-7 human breast cancer cellsQ40867507
Phosphoinositide 3-kinase induces the transcriptional activity of MEF2 proteins during muscle differentiationQ40868357
Phosphatidylinositol 3-kinase inhibitors block differentiation of skeletal muscle cellsQ41175824
IGF-I is required for normal embryonic growth in miceQ41510465
Phosphoinositide 3-kinase: the key switch mechanism in insulin signallingQ42991205
P433issue24
P407language of work or nameEnglishQ1860
P921main subjectmorphogenesisQ815547
P1104number of pages8
P304page(s)21998-22005
P577publication date2003-03-27
P1433published inJournal of Biological ChemistryQ867727
P1476titlePhosphatidylinositol 3-kinase regulates bone morphogenetic protein-2 (BMP-2)-induced myocyte enhancer factor 2A-dependent transcription of BMP-2 gene in cardiomyocyte precursor cells
P478volume278

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