BRD7 suppresses the growth of Nasopharyngeal Carcinoma cells (HNE1) through negatively regulating beta-catenin and ERK pathways

scientific article published on 26 April 2007

BRD7 suppresses the growth of Nasopharyngeal Carcinoma cells (HNE1) through negatively regulating beta-catenin and ERK pathways is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S11010-007-9466-X
P8608Fatcat IDrelease_iy4l4q34gjctrgl767q33wzvey
P698PubMed publication ID17458518

P2093author name stringMing Zhou
Cong Peng
Xiao Ling Li
Li Ming Zhang
Gui Yuan Li
Shou Rong Shen
Hua Ying Liu
P2860cites workMolecular characterization of celtix-1, a bromodomain protein interacting with the transcription factor interferon regulatory factor 2Q24290379
Regulation of the PH-domain-containing tyrosine kinase Etk by focal adhesion kinase through the FERM domainQ24291190
The transcriptional regulation role of BRD7 by binding to acetylated histone through bromodomainQ24293463
Regulation of transcription by the heterogeneous nuclear ribonucleoprotein E1B-AP5 is mediated by complex formation with the novel bromodomain-containing protein BRD7Q24337326
Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/AKT by the integrin-linked kinaseQ24682825
The Hedgehog and Wnt signalling pathways in cancerQ28189485
Cell adhesion and the integrin-linked kinase regulate the LEF-1 and beta-catenin signaling pathwaysQ28571378
Researching a novel NPC-related candidate suppressor gene BRD7 by two-dimensional gel electrophoresis and MALDI-TOF-MSQ30980491
Screening of BRD7 interacting proteins by yeast two-hybrid systemQ33365053
The dual role of cytoskeletal anchor proteins in cell adhesion and signal transductionQ33833342
BRD7, a novel bromodomain gene, inhibits G1-S progression by transcriptionally regulating some important molecules involved in ras/MEK/ERK and Rb/E2F pathwaysQ34320007
The Raf/MEK/ERK pathway: new concepts of activation.Q34454912
Mitogen activated protein (MAP) kinase signal transduction pathways and novel anti-inflammatory targets.Q35023644
Transgenic mice demonstrate AP-1 (activator protein-1) transactivation is required for tumor promotionQ36436367
Gene expression profiling of nasopharyngeal carcinoma reveals the abnormally regulated Wnt signaling pathwayQ38309301
Ternary complex factors: growth factor regulated transcriptional activatorsQ40757584
Inhibitors of both nuclear factor-kappaB and activator protein-1 activation block the neoplastic transformation response.Q41093962
Mitogen-activated protein kinase/extracellular signal-regulated protein kinase activation by oncogenes, serum, and 12-O-tetradecanoylphorbol-13-acetate requires Raf and is necessary for transformationQ41481475
Beta-catenin: a key mediator of Wnt signalingQ41732761
Signal transduction through MAP kinase cascadesQ41750250
Both ERK and Wnt/beta-catenin pathways are involved in Wnt3a-induced proliferationQ42472178
Differential signaling pathways are activated in the Epstein-Barr virus-associated malignancies nasopharyngeal carcinoma and Hodgkin lymphomaQ45605928
Chromosomal aberrations in nasopharyngeal carcinoma analyzed by comparative genomic hybridization.Q53423354
Loss of heterozygosity on chromosome arm 3p in nasopharyngeal carcinomaQ71769244
Genome-wide allelotype analysis of sporadic primary nasopharyngeal carcinoma from southern ChinaQ73191186
Expression of c-erbB receptors, heregulin and oestrogen receptor in human breast cell linesQ74081713
Genome-wide scan for familial nasopharyngeal carcinoma reveals evidence of linkage to chromosome 4Q74462924
Signaling from G-protein-coupled receptors to mitogen-activated protein (MAP)-kinase cascadesQ77322545
Downregulation and abnormal expression of E-cadherin and beta-catenin in nasopharyngeal carcinoma: close association with advanced disease stage and lymph node metastasisQ77340409
Loss of heterozygosity on chromosome 14 in nasopharyngeal carcinomaQ77354036
Detection of recurrent chromosomal gains and losses in primary nasopharyngeal carcinoma by comparative genomic hybridisationQ77995454
A susceptibility locus at chromosome 3p21 linked to familial nasopharyngeal carcinomaQ79787068
Detailed deletion mapping on the short arm of chromosome-3 in nasopharyngeal carcinomasQ84089664
P433issue1-2
P304page(s)141-149
P577publication date2007-04-26
P1433published inMolecular and Cellular BiochemistryQ1573176
P1476titleBRD7 suppresses the growth of Nasopharyngeal Carcinoma cells (HNE1) through negatively regulating beta-catenin and ERK pathways
P478volume303

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cites work (P2860)
Q46493497A genomic screen for angiosuppressor genes in the tumor endothelium identifies a multifaceted angiostatic role for bromodomain containing 7 (BRD7).
Q99413660BRD4/8/9 are prognostic biomarkers and associated with immune infiltrates in hepatocellular carcinoma
Q55119106BRD7 inhibits the Warburg effect and tumor progression through inactivation of HIF1α/LDHA axis in breast cancer.
Q24303120BRD7 is a candidate tumour suppressor gene required for p53 function
Q33684240BRD7 mediates hyperglycaemia-induced myocardial apoptosis via endoplasmic reticulum stress signalling pathway
Q38760091BRD7 plays an anti-inflammatory role during early acute inflammation by inhibiting activation of the NF-кB signaling pathway
Q33838482BRD7 regulates XBP1s' activity and glucose homeostasis through its interaction with the regulatory subunits of PI3K
Q47414450BRD7 regulates the insulin-signaling pathway by increasing phosphorylation of GSK3β.
Q89579657BRD7 suppresses invasion and metastasis in breast cancer by negatively regulating YB1-induced epithelial-mesenchymal transition
Q26751298BRD7: a novel tumor suppressor gene in different cancers
Q37086000Bromodomain-containing protein 7 (BRD7) as a potential tumor suppressor in hepatocellular carcinoma
Q24308923Ceap/BLOS2 interacts with BRD7 and selectively inhibits its transcription-suppressing effect on cellular proliferation-associated genes
Q64941197Clinical significance of bromodomain-containing protein 7 and its association with tumor progression in prostate cancer.
Q54933469Design and synthesis of potent and selective inhibitors of BRD7 and BRD9 bromodomains
Q28542858Inhibition of TMEM16A expression suppresses growth and invasion in human colorectal cancer cells
Q38457229Integrating ChIP-sequencing and digital gene expression profiling to identify BRD7 downstream genes and construct their regulating network
Q34514258Knockout of BRD7 results in impaired spermatogenesis and male infertility
Q34708453LPLUNC1 inhibits nasopharyngeal carcinoma cell growth via down-regulation of the MAP kinase and cyclin D1/E2F pathways
Q38790987Low concentration of formononetin stimulates the proliferation of nasopharyngeal carcinoma cell line CNE2 by upregulating bcl-2 and p-ERK1/2 expression
Q38856137MicroRNA-410 promotes cell proliferation by targeting BRD7 in non-small cell lung cancer
Q27704896NMR Fragment Screening Hit Induces Plasticity of BRD7/9 Bromodomains
Q34611577Nasopharyngeal carcinoma--review of the molecular mechanisms of tumorigenesis
Q92800638Poly(ADP-ribosyl)ation of BRD7 by PARP1 confers resistance to DNA-damaging chemotherapeutic agents
Q34069831Polybromo-associated BRG1-associated factor components BRD7 and BAF180 are critical regulators of p53 required for induction of replicative senescence
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Q33367808Promoter methylation inhibits BRD7 expression in human nasopharyngeal carcinoma cells
Q38795544Pyruvate dehydrogenase B promoted the growth and migration of the nasopharyngeal carcinoma cells.
Q34614284SPLUNC1 regulates cell progression and apoptosis through the miR-141-PTEN/p27 pathway, but is hindered by LMP1.
Q37260036Signaling Transduction Network Mediated by Tumor Suppressor/Susceptibility Genes in NPC.
Q36925822Structural basis of protein-protein interaction studied by NMR.
Q24316908TRIM24 mediates ligand-dependent activation of androgen receptor and is repressed by a bromodomain-containing protein, BRD7, in prostate cancer cells
Q33917573Targeting the anaphase-promoting complex/cyclosome (APC/C)- bromodomain containing 7 (BRD7) pathway for human osteosarcoma
Q99629107The BRD7-P53-SLC25A28 axis regulates ferroptosis in hepatic stellate cells
Q39455273The interactions between MicroRNA-200c and BRD7 in endometrial carcinoma
Q37117156The role of BRD7 in embryo development and glucose metabolism
Q42009542Tumor suppressor bromodomain-containing protein 7 cooperates with Smads to promote transforming growth factor-β responses
Q36905617XIAP-associating factor 1, a transcriptional target of BRD7, contributes to endothelial cell senescence
Q55449419[Expression and clinical significance of bromodomain-containing protein 7 in non-small cell lung cancer].
Q36775043miR-141 is involved in BRD7-mediated cell proliferation and tumor formation through suppression of the PTEN/AKT pathway in nasopharyngeal carcinoma

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