Dietary restriction protects hippocampal neurons against the death-promoting action of a presenilin-1 mutation

scientific article published in September 1999

Dietary restriction protects hippocampal neurons against the death-promoting action of a presenilin-1 mutation is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0006-8993(99)01827-2
P698PubMed publication ID10526115

P2093author name stringZhu H
Mattson MP
Guo Q
P2860cites workIncreased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1Q28118975
Neurotrophic factors [activity-dependent neurotrophic factor (ADNF) and basic fibroblast growth factor (bFGF)] interrupt excitotoxic neurodegenerative cascades promoted by a PS1 mutationQ28506810
Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's diseaseQ29614374
Oxidative stress, caloric restriction, and agingQ29618229
The retardation of aging in mice by dietary restriction: longevity, cancer, immunity and lifetime energy intakeQ34051250
Oxidative damage, mitochondrial oxidant generation and antioxidant defenses during aging and in response to food restriction in the mouseQ34323890
The stress protein response in cultured neurons: characterization and evidence for a protective role in excitotoxicityQ34654146
Role of free radicals in aging and diseaseQ35659457
Calbindin D28k blocks the proapoptotic actions of mutant presenilin 1: reduced oxidative stress and preserved mitochondrial functionQ35984381
Excitatory amino acids and Alzheimer's diseaseQ38301056
Bioenergetic and oxidative stress in neurodegenerative diseasesQ40369216
beta-Amyloid precursor protein metabolites and loss of neuronal Ca2+ homeostasis in Alzheimer's disease.Q40384274
Amyloid, the presenilins and Alzheimer's diseaseQ41433661
Cellular actions of beta-amyloid precursor protein and its soluble and fibrillogenic derivativesQ41630805
4-Hydroxynonenal, a product of lipid peroxidation, damages cholinergic neurons and impairs visuospatial memory in ratsQ42455640
Caspase dependent DNA fragmentation might be associated with excitotoxicity in Alzheimer diseaseQ45213177
Increased Transcription of the Astrocyte Gene GFAP During Middle-Age is Attenuated by Food Restriction: Implications for the Role of Oxidative StressQ46062754
Chronic caloric restriction induces stress proteins in the hypothalamus of ratsQ46140259
Dietary restriction: effects on radial maze learning and lipofuscin pigment deposition in the hippocampus and frontal cortexQ48175731
The endoplasmic reticulum stress-responsive protein GRP78 protects neurons against excitotoxicity and apoptosis: suppression of oxidative stress and stabilization of calcium homeostasisQ48266667
Altered calcium homeostasis and mitochondrial dysfunction in cortical synaptic compartments of presenilin-1 mutant miceQ48275838
Increased vulnerability of hippocampal neurons from presenilin-1 mutant knock-in mice to amyloid beta-peptide toxicity: central roles of superoxide production and caspase activationQ48275849
Increased vulnerability of hippocampal neurons to excitotoxic necrosis in presenilin-1 mutant knock-in miceQ48308608
Melatonin protects hippocampal neurons in vivo against kainic acid-induced damage in miceQ48348653
Protein oxidation and enzyme activity decline in old brown Norway rats are reduced by dietary restrictionQ48491092
Elevated 4-hydroxynonenal in ventricular fluid in Alzheimer's diseaseQ48589531
Impairment of glucose and glutamate transport and induction of mitochondrial oxidative stress and dysfunction in synaptosomes by amyloid beta-peptide: role of the lipid peroxidation product 4-hydroxynonenalQ48677217
Alzheimer's presenilin mutation sensitizes neural cells to apoptosis induced by trophic factor withdrawal and amyloid beta-peptide: involvement of calcium and oxyradicals.Q48703300
Widespread peroxynitrite-mediated damage in Alzheimer's diseaseQ48728343
The effects of life-long food restriction on spatial memory in young and aged Fischer 344 rats measured in the eight-arm radial and the Morris water mazesQ48914244
Effect of age and caloric intake on protein oxidation in different brain regions and on behavioral functions of the mouseQ48934444
Caloric restriction increases the expression of heat shock protein in the gut.Q51581731
Deterioration of spatial and nonspatial reference and working memory in aged rats: protective effect of life-long calorie restriction.Q52075498
Dietary restriction benefits learning and motor performance of aged mice.Q52258125
Dietary lipids and antioxidants in Parkinson's disease: a population-based, case-control studyQ70928225
Monoclonal antibodies for detection of 4-hydroxynonenal modified proteinsQ71713576
Neurotrophic factors attenuate glutamate-induced accumulation of peroxides, elevation of intracellular Ca2+ concentration, and neurotoxicity and increase antioxidant enzyme activities in hippocampal neuronsQ71748788
Generation of lipid radicals in the hippocampal extracellular space during kainic acid-induced seizures in ratsQ73206492
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)224-229
P577publication date1999-09-01
P1433published inBrain ResearchQ4955782
P1476titleDietary restriction protects hippocampal neurons against the death-promoting action of a presenilin-1 mutation
P478volume842

Reverse relations

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