Association of factor H of the alternative pathway of complement with agrin and complement receptor 3 in the Alzheimer's disease brain.

scientific article published in October 2002

Association of factor H of the alternative pathway of complement with agrin and complement receptor 3 in the Alzheimer's disease brain. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0165-5728(02)00272-2
P698PubMed publication ID12458045

P2093author name stringJoseph Rogers
Kyle Mueller
Gregory J Cole
Mauricio Ramirez
Ron Strohmeyer
P2860cites workAgrin binds to beta-amyloid (Abeta), accelerates abeta fibril formation, and is localized to Abeta deposits in Alzheimer's disease brainQ22253180
RAGE and amyloid-beta peptide neurotoxicity in Alzheimer's diseaseQ24314906
Integrins: versatility, modulation, and signaling in cell adhesionQ27860844
Inflammation and Alzheimer's diseaseQ28138617
Complement factor H and related proteins: an expanding family of complement-regulatory proteins?Q28252778
An important role of heparan sulfate proteoglycan (Perlecan) in a model system for the deposition and persistence of fibrillar A beta-amyloid in rat brainQ28258921
Agrin in Alzheimer's disease: altered solubility and abnormal distribution within microvasculature and brain parenchymaQ28645584
Identification of human complement Factor H as a ligand for L-selectinQ29543695
Function and activation of NF-kappa B in the immune systemQ29547790
Widespread serum amyloid P immunoreactivity in cortical amyloid deposits and the neurofibrillary pathology of Alzheimer's disease and other degenerative disordersQ33376704
The role of integrins in immune-mediated diseases of the nervous systemQ33544245
FHL-1/reconectin: a human complement and immune regulator with cell-adhesive functionQ33594106
The factor H protein familyQ33688567
Prominent neurodegeneration and increased plaque formation in complement-inhibited Alzheimer's miceQ34076162
NF-kappa B: a crucial transcription factor for glial and neuronal cell functionQ34428983
Biochemical and functional characterization of the factor-H-related protein 4 (FHR-4).Q34457545
Complement proteins and complement inhibitors in Alzheimer's diseaseQ35556129
Agrin is a major heparan sulfate proteoglycan accumulating in Alzheimer's disease brain.Q35787956
Amyloid-beta peptide-receptor for advanced glycation endproduct interaction elicits neuronal expression of macrophage-colony stimulating factor: a proinflammatory pathway in Alzheimer diseaseQ36771851
Proteoglycans as modulators of growth factor activitiesQ37656847
Glycosaminoglycans: molecular properties, protein interactions, and role in physiological processesQ37671601
Microangiopathy, the vascular basement membrane and Alzheimer's disease: a reviewQ37934582
Transcriptional regulation of the interleukin-1beta promoter via fibrinogen engagement of the CD18 integrin receptorQ38325141
Proteoglycans in the pathogenesis of Alzheimer's disease and other amyloidosesQ38715604
The human complement regulatory factor-H-like protein 1, which represents a truncated form of factor H, displays cell-attachment activityQ39063137
Detection and quantitation of perlecan mRNA levels in Alzheimer's disease and normal aged hippocampus by competitive reverse transcription-polymerase chain reactionQ39114018
Complement biosynthesis in the central nervous systemQ40406085
Proteoglycans on endothelial cells present adhesion-inducing cytokines to leukocytes.Q40893812
Integrins: possible functions in the adult CNS.Q41120781
Scavenger receptor-mediated adhesion of microglia to beta-amyloid fibrilsQ41173971
The NF-kappa B/Rel and I kappa B gene families: mediators of immune response and inflammationQ41280940
Alzheimer's disease and heparan sulfate proteoglycan.Q41715940
Microglia, scavenger receptors, and the pathogenesis of Alzheimer's diseaseQ41751577
Thioflavine T interaction with synthetic Alzheimer's disease beta-amyloid peptides: detection of amyloid aggregation in solutionQ42153291
Identification of extracellular matrix ligands for the heparan sulfate proteoglycan agrinQ42472113
Identification of human complement factor H as a chemotactic protein for monocytes.Q42987610
Evidence for an active hydrophobic form of factor H that is able to induce secretion of interleukin 1-β or by human monocytesQ46237179
A new biological activity of the complement factor H: identification of the precursor of the major macrophage-chemotactic factor in delayed hypersensitivity reaction sites of guinea pigsQ46729890
Localization of heparan sulfate glycosaminoglycan and proteoglycan core protein in aged brain and Alzheimer's diseaseQ46852742
Complement regulationQ47686748
Mechanisms of cell death in Alzheimer disease--immunopathology.Q48330745
The importance of inflammatory mechanisms in Alzheimer diseaseQ48380991
Integrin Mac-1 and beta-amyloid in microglial release of nitric oxide.Q48593698
Brain microglia constitutively express beta-2 integrins.Q48874195
Microglial cells internalize aggregates of the Alzheimer's disease amyloid beta-protein via a scavenger receptor.Q48933977
Detection of complement alternative pathway mRNA and proteins in the Alzheimer's disease brain.Q53237812
Crucial role of heparan sulfate proteoglycan (agrin) in beta-amyloid formation in Alzheimer's disease.Q53238449
Chemotactic-like receptors and Abeta peptide induced responses in Alzheimer's disease.Q53341475
Binding of vascular heparan sulfate proteoglycan to Alzheimer's amyloid precursor protein is mediated in part by the N-terminal region of A4 peptideQ57897218
Heparin specifically inhibits binding of apolipoprotein E to amyloid β-peptideQ57996004
Kinetics of apolipoprotein E isoforms-binding to the major glycosaminoglycans of the extracellular matrixQ57996135
Proteoglycans and the extracellular matrix in amyloidosisQ58283024
Agrin and microvascular damage in Alzheimer’s diseaseQ60145604
Induction of cell-associated interleukin 1 through stimulation of the adhesion-promoting proteins LFA-1 (CD11a/CD18) and CR3 (CD11b/CD18) of human monocytesQ67662039
Solution conformations and aggregational properties of synthetic amyloid beta-peptides of Alzheimer's disease. Analysis of circular dichroism spectraQ68173181
pH-dependent binding of synthetic beta-amyloid peptides to glycosaminoglycansQ72621597
Regulation of alternative pathway complement activation by glycosaminoglycans: specificity of the polyanion binding site on factor HQ72733127
Lipid mediators up-regulate CD11b and prime for concordant superoxide and elastase release in human neutrophilsQ73684083
CD11/CD18 leukocyte integrins: new signaling receptors for bacterial endotoxinQ74087960
Localization of human serum amyloid P component and heparan sulfate proteoglycan in in vitro-formed Abeta fibrilsQ74130148
Molecular and cellular mediators of Alzheimer's disease inflammationQ74736408
P433issue1-2
P921main subjectAlzheimer's diseaseQ11081
P304page(s)135-146
P577publication date2002-10-01
P1433published inJournal of NeuroimmunologyQ15716691
P1476titleAssociation of factor H of the alternative pathway of complement with agrin and complement receptor 3 in the Alzheimer's disease brain.
P478volume131

Reverse relations

cites work (P2860)
Q42026180Amyloid-β sequester proteins as blood-based biomarkers of cognitive decline
Q33920123Apolipoprotein E allele-dependent pathogenesis: a model for age-related retinal degeneration
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Q37505868CCAAT-enhancer binding protein-β expression and elevation in Alzheimer's disease and microglial cell cultures
Q36565635CFH Variants Affect Structural and Functional Brain Changes and Genetic Risk of Alzheimer's Disease
Q41897818CSF Biomarkers for Alzheimer's Disease Diagnosis
Q36592268CSF complement 3 and factor H are staging biomarkers in Alzheimer's disease
Q30665205Complement component C3 and complement receptor type 3 contribute to the phagocytosis and clearance of fibrillar Aβ by microglia
Q53290404Complement factor H Y402H polymorphism is not associated with late-onset Alzheimer's disease.
Q37872442Complement in the brain.
Q30665192Complement receptor 3 (CD11b/CD18) is implicated in the elimination of β-amyloid peptides
Q38362621Complementing the Sugar Code: Role of GAGs and Sialic Acid in Complement Regulation
Q37769045Corruption of homeostatic mechanisms in the guanylyl cyclase C signaling pathway underlying colorectal tumorigenesis
Q42103651Deletion of Crry, the murine ortholog of the sporadic Alzheimer's disease risk gene CR1, impacts tau phosphorylation and brain CFH.
Q38223669Factor h: a complement regulator in health and disease, and a mediator of cellular interactions.
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Q41705490Identification of factor H-like protein 1 as the predominant complement regulator in Bruch's membrane: implications for age-related macular degeneration.
Q35677347Immune aging, dysmetabolism, and inflammation in neurological diseases
Q38120744Innate immunity and neuroinflammation
Q34630522Low levels of cerebrospinal fluid complement 3 and factor H predict faster cognitive decline in mild cognitive impairment
Q38195641Microglia receptors and their implications in the response to amyloid β for Alzheimer's disease pathogenesis
Q42322507Microglia, Alzheimer's disease, and complement
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Q58738012Two distinct conformations of factor H regulate discrete complement-binding functions in the fluid phase and at cell surfaces
Q24796236Using animal models to determine the significance of complement activation in Alzheimer's disease
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Q38887260c-Jun and c-Fos regulate the complement factor H promoter in murine astrocytes

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