review article | Q7318358 |
scholarly article | Q13442814 |
P356 | DOI | 10.1016/S0531-5565(98)00013-8 |
P698 | PubMed publication ID | 9762518 |
P2093 | author name string | McGeer PL | |
McGeer EG | |||
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P433 | issue | 5 | |
P921 | main subject | Alzheimer's disease | Q11081 |
inflammation | Q101991 | ||
P304 | page(s) | 371-378 | |
P577 | publication date | 1998-08-01 | |
P1433 | published in | Experimental Gerontology | Q15766996 |
P1476 | title | The importance of inflammatory mechanisms in Alzheimer disease. | |
P478 | volume | 33 |
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Q64943218 | A Precision Medicine Model for Targeted NSAID Therapy in Alzheimer's Disease. |
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Q42247119 | A changing perspective on the role of neuroinflammation in Alzheimer's disease |
Q26997058 | A deficiency in CCR2+ monocytes: the hidden side of Alzheimer's disease |
Q52025813 | A polymorphism in the complement component C1r is not associated with sporadic Alzheimer's disease. |
Q44241464 | Absence of C1q leads to less neuropathology in transgenic mouse models of Alzheimer's disease. |
Q37319542 | Accuracy of hippocampal network activity is disrupted by neuroinflammation: rescue by memantine |
Q48447497 | Aerosol Delivery of Curcumin Reduced Amyloid-β Deposition and Improved Cognitive Performance in a Transgenic Model of Alzheimer's Disease. |
Q36721813 | Age-related inflammatory diseases: role of genetics and gender in the pathophysiology of Alzheimer's disease |
Q21128630 | Age-related neuroinflammatory changes negatively impact on neuronal function |
Q34360848 | Ageing, science and the cosmetics industry. The micro-inflammatory model serves as a basis for developing effective anti-ageing products for the skin |
Q44684179 | Allele frequencies of +874T --> A single nucleotide polymorphism at the first intron of IFN-gamma gene in Alzheimer's disease patients |
Q41929659 | Allergy influences the inflammatory status of the brain and enhances tau-phosphorylation. |
Q45255505 | Altered cytokine and acute phase response protein levels in the blood of children with Downs syndrome: relationship with dementia of Alzheimer's type |
Q37034397 | Alzheimer's disease and genetics of inflammation: a pharmacogenomic vision |
Q34646469 | Ammonia and Alzheimer's disease |
Q37358028 | Amyloid-beta(1-42) fibrillar precursors are optimal for inducing tumor necrosis factor-alpha production in the THP-1 human monocytic cell line |
Q36654872 | Amyloid-β(1-42) protofibrils formed in modified artificial cerebrospinal fluid bind and activate microglia |
Q34302262 | Amyloid-β(1-42) protofibrils stimulate a quantum of secreted IL-1β despite significant intracellular IL-1β accumulation in microglia |
Q44060081 | Association between high-density lipoprotein and cognitive impairment in the oldest old. |
Q48939488 | Association between polymorphism in regulatory region of gene encoding tumour necrosis factor alpha and risk of Alzheimer's disease and vascular dementia: a case-control study. |
Q36882004 | Association of alleles carried at TNFA -850 and BAT1 -22 with Alzheimer's disease |
Q48435905 | Association of factor H of the alternative pathway of complement with agrin and complement receptor 3 in the Alzheimer's disease brain. |
Q92689483 | Astrocyte senescence promotes glutamate toxicity in cortical neurons |
Q51952390 | Atherosclerosis and cognitive impairment are linked in the elderly. The Leiden 85-plus Study. |
Q89495923 | Benefits of aged garlic extract on Alzheimer's disease: Possible mechanisms of action |
Q53236327 | Brain inflammatory reaction in an animal model of neuronal degeneration and its modulation by an anti-inflammatory drug: implication in Alzheimer's disease. |
Q35032515 | CD47 does not mediate amyloid-β(1-42) protofibril-stimulated microglial cytokine release |
Q33689076 | Can peripheral leukocytes be used as Alzheimer's disease biomarkers? |
Q28478463 | Characterization of a Drosophila Alzheimer's disease model: pharmacological rescue of cognitive defects |
Q26748974 | Chronic Stress and Glucocorticoids: From Neuronal Plasticity to Neurodegeneration |
Q39630580 | Chronic brain inflammation causes a reduction in GluN2A and GluN2B subunits of NMDA receptors and an increase in the phosphorylation of mitogen-activated protein kinases in the hippocampus |
Q24796326 | Chronic brain inflammation leads to a decline in hippocampal NMDA-R1 receptors |
Q33882627 | Clinical pharmacokinetics and pharmacodynamics of celecoxib: a selective cyclo-oxygenase-2 inhibitor |
Q34631859 | Clozapine protects dopaminergic neurons from inflammation-induced damage by inhibiting microglial overactivation |
Q34071528 | Common gene variants, mortality and extreme longevity in humans. |
Q36891064 | Curcumin: a natural substance with potential efficacy in Alzheimer's disease |
Q48597699 | Cyclooxygenase-2-positive macrophages infiltrate the Alzheimer's disease brain and damage the blood-brain barrier. |
Q73225523 | Cytokine regulation of CD40 expression in fetal human astrocyte cultures |
Q53353949 | Decrease of TGF-beta1 plasma levels and increase of nitric oxide synthase activity in leukocytes as potential biomarkers of Alzheimer's disease. |
Q34826210 | Degeneration of neuronal cells due to oxidative stress--microglial contribution |
Q48791445 | Depiction of microglial activation in aging and dementia: Positron emission tomography with [11C]DPA713 versus [11C]( R)PK11195. |
Q53237812 | Detection of complement alternative pathway mRNA and proteins in the Alzheimer's disease brain. |
Q34658937 | Dietary flavonoids as potential neuroprotectants |
Q41825402 | Differential effects of Th1, monocyte/macrophage and Th2 cytokine mixtures on early gene expression for glial and neural-related molecules in central nervous system mixed glial cell cultures: neurotrophins, growth factors and structural proteins |
Q36931725 | Dual role of CD38 in microglial activation and activation-induced cell death. |
Q37331433 | Dystrophic (senescent) rather than activated microglial cells are associated with tau pathology and likely precede neurodegeneration in Alzheimer's disease |
Q43734948 | Early behavioural changes in scrapie-affected mice and the influence of dapsone |
Q53250180 | Early inflammation and dementia: a 25-year follow-up of the Honolulu-Asia Aging Study. |
Q36245937 | Effects and possible mechanisms of action of acacetin on the behavior and eye morphology of Drosophila models of Alzheimer's disease |
Q39980648 | Electrophilic cyclopentenone neuroprostanes are anti-inflammatory mediators formed from the peroxidation of the omega-3 polyunsaturated fatty acid docosahexaenoic acid |
Q36831055 | Enhanced prostacyclin synthesis by adenoviral gene transfer reduced glial activation and ameliorated dopaminergic dysfunction in hemiparkinsonian rats |
Q38001328 | Essential roles of gangliosides in the formation and maintenance of membrane microdomains in brain tissues |
Q73447675 | Evidence for glial-mediated inflammation in aged APP(SW) transgenic mice |
Q37155141 | Expression and localization of lactotransferrin messenger RNA in the cortex of Alzheimer's disease |
Q34951817 | Function and comorbidities of apolipoprotein e in Alzheimer's disease |
Q37702966 | Ganglioside deficiency causes inflammation and neurodegeneration via the activation of complement system in the spinal cord |
Q30492292 | Gangliosides play pivotal roles in the regulation of complement systems and in the maintenance of integrity in nerve tissues |
Q34154632 | Gene expression reveals overlap between normal aging and Alzheimer's disease genes |
Q53108080 | Genetic polymorphism of interleukin 1β -511C/T and susceptibility to sporadic Alzheimer's disease: a meta-analysis. |
Q37610265 | Genomics of immune molecules: early detection of cognitive decline and new therapeutic interventions |
Q36914297 | Guarding the blood-brain barrier: a role for estrogen in the etiology of neurodegenerative disease. |
Q41090932 | Hsp70 alters tau function and aggregation in an isoform specific manner |
Q40672202 | Hypothermia suppresses inducible nitric oxide synthase and stimulates cyclooxygenase-2 in lipopolysaccharide stimulated BV-2 cells |
Q41749781 | Ibuprofen suppresses plaque pathology and inflammation in a mouse model for Alzheimer's disease. |
Q33881161 | Identification of 167 polymorphisms in 88 genes from candidate neurodegeneration pathways |
Q36460445 | Immunology and immunotherapy of Alzheimer's disease |
Q36312711 | Immunophenotypes in the circulation of patients with mild cognitive impairment |
Q35573436 | Immunotherapeutic Approaches to Alzheimer's Disease |
Q35169132 | Increased T cell reactivity to amyloid beta protein in older humans and patients with Alzheimer disease |
Q53233114 | Increased plasma levels of interleukin-1, interleukin-6 and alpha-1-antichymotrypsin in patients with Alzheimer's disease: peripheral inflammation or signals from the brain? |
Q35792619 | Increased production of inflammatory cytokines in mild cognitive impairment |
Q44807284 | Induction of cyclooxygenase-2 and peroxisome proliferator-activated receptor-gamma during nitric oxide-induced apoptotic PC12 cell death |
Q48895241 | Inflammation and Alzheimer disease: the good, the bad, and the ugly. |
Q35030005 | Inflammation and therapeutic vaccination in CNS diseases |
Q37685285 | Inflammation in Alzheimer's disease: relevance to pathogenesis and therapy |
Q36380232 | Inflammatory changes parallel the early stages of Alzheimer disease |
Q53232489 | Inflammatory mechanisms in Alzheimer's disease: inhibition of beta-amyloid-stimulated proinflammatory responses and neurotoxicity by PPARgamma agonists. |
Q34401462 | Inflammatory regulation of ATP binding cassette efflux transporter expression and function in microglia |
Q24814846 | Innate immunity and inflammation in ageing: a key for understanding age-related diseases |
Q37051184 | Interleukin 6 plasma concentration associates with cognitive decline: the northern Manhattan study |
Q53357994 | Interleukin-10 promoter polymorphism in sporadic Alzheimer's disease. |
Q48222290 | Interleukin-6 gene alleles affect the risk of Alzheimer's disease and levels of the cytokine in blood and brain |
Q51021135 | Involvement of interleukin-1 in lipopolysaccaride-induced microglial activation and learning and memory deficits. |
Q35917735 | Involvement of metabotropic glutamate receptor 5, AKT/PI3K signaling and NF-κB pathway in methamphetamine-mediated increase in IL-6 and IL-8 expression in astrocytes. |
Q28575185 | Involvement of the intracellular ion channel CLIC1 in microglia-mediated beta-amyloid-induced neurotoxicity |
Q36109443 | Isolated amyloid-β(1-42) protofibrils, but not isolated fibrils, are robust stimulators of microglia |
Q40765436 | Lactoferrin is synthesized by activated microglia in the human substantia nigra and its synthesis by the human microglial CHME cell line is upregulated by tumor necrosis factor alpha or 1-methyl-4-phenylpyridinium treatment |
Q54939485 | Lychee Seed Fraction Inhibits Aβ(1-42)-Induced Neuroinflammation in BV-2 Cells via NF-κB Signaling Pathway. |
Q48159922 | Matrix metalloproteinases in peripheral blood and cerebrospinal fluid in patients with Alzheimer's disease |
Q42491893 | Mechanisms to prevent the toxicity of chronic neuroinflammation on forebrain cholinergic neurons |
Q36824990 | Memory-enhancing effect of aspirin is mediated through opioid system modulation in an AlCl3-induced neurotoxicity mouse model |
Q43918834 | Microglial activation and beta -amyloid deposit reduction caused by a nitric oxide-releasing nonsteroidal anti-inflammatory drug in amyloid precursor protein plus presenilin-1 transgenic mice. |
Q38082670 | Molecular basis of etiological implications in Alzheimer's disease: focus on neuroinflammation |
Q42577142 | Multi factorial interactions in the pathogenesis pathway of Alzheimer's disease: a new risk charts for prevention of dementia |
Q73755556 | Naloxone prevents microglia-induced degeneration of dopaminergic substantia nigra neurons in adult rats |
Q64854489 | Neurodegenerative disorders: the role of peroxynitrite |
Q42473123 | Neuroinflammation alters the hippocampal pattern of behaviorally induced Arc expression. |
Q37841810 | Neuroinflammation and the plasticity-related immediate-early gene Arc. |
Q27014919 | Neuroinflammation in Alzheimer's disease; A source of heterogeneity and target for personalized therapy |
Q33663970 | Neuroinflammation in Parkinson's disease: its role in neuronal death and implications for therapeutic intervention |
Q43936618 | Neuroinflammation of the nigrostriatal pathway during progressive 6-OHDA dopamine degeneration in rats monitored by immunohistochemistry and PET imaging. |
Q36919403 | Neuroinflammatory mechanisms in Parkinson's disease: potential environmental triggers, pathways, and targets for early therapeutic intervention |
Q37628345 | Neuroprotective Effects of Aged Garlic Extract on Cognitive Dysfunction and Neuroinflammation Induced by β-Amyloid in Rats |
Q43992276 | Neutrophils CD11b and fibroblasts PGE(2) are elevated in Alzheimer's disease |
Q99238404 | Nicotinamide, a Poly [ADP-Ribose] Polymerase 1 (PARP-1) Inhibitor, as an Adjunctive Therapy for the Treatment of Alzheimer's Disease |
Q46241778 | Optimized-SopungSunkiwon, a Herbal Formula, Attenuates Aβ Oligomer-Induced Neurotoxicity in Alzheimer's Disease Models. |
Q34192388 | Overview and perspective on the therapy of Alzheimer's disease from a preclinical viewpoint |
Q36635045 | Pathogenesis of cognitive dysfunction in patients with obstructive sleep apnea: a hypothesis with emphasis on the nucleus tractus solitarius |
Q73405979 | Patients with Alzheimer's disease display a pro-inflammatory phenotype |
Q47284845 | Peripheral inflammation in prodromal Alzheimer's and Lewy body dementias |
Q44459219 | Persistent protease-activated receptor 4 signaling mediates thrombin-induced microglial activation |
Q31859338 | Post-dexamethasone cortisol level and memory performance in elderly depressed patients |
Q47127820 | Promoter haplotypes of interleukin-10 gene linked to cortex plasticity in subjects with risk of Alzheimer's disease |
Q38239636 | Protease-activated receptor 4: a critical participator in inflammatory response |
Q73191513 | Regional and age-related expression of gelatinases in the brains of young and old rats after treatment with kainic acid |
Q35050412 | Regulation of microglia - potential new drug targets in the CNS. |
Q37874462 | Regulatory mechanisms of nervous systems with glycosphingolipids |
Q37233240 | Relationship between plasma lipids and mild cognitive impairment in the elderly Chinese: a case-control study |
Q35025023 | Risk factors for Alzheimer's disease: role of multiple antioxidants, non-steroidal anti-inflammatory and cholinergic agents alone or in combination in prevention and treatment |
Q37889475 | Risk profiles of Alzheimer disease |
Q48459353 | Role of CD40 ligand in amyloidosis in transgenic Alzheimer's mice. |
Q34400646 | Role of free radicals in the neurodegenerative diseases: therapeutic implications for antioxidant treatment |
Q53324311 | Role of interleukin 6 and alpha-globulins in differentiating Alzheimer and vascular dementias. |
Q41819939 | S100B Inhibitor Pentamidine Attenuates Reactive Gliosis and Reduces Neuronal Loss in a Mouse Model of Alzheimer's Disease. |
Q51895354 | Serum albumin levels predict cognitive impairment in elderly hip fracture patients. |
Q44880812 | Sulindac improves memory and increases NMDA receptor subunits in aged Fischer 344 rats. |
Q40267347 | TRPM2 is elevated in the tMCAO stroke model, transcriptionally regulated, and functionally expressed in C13 microglia. |
Q35846770 | Temporal mRNA profiles of inflammatory mediators in the murine 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrimidine model of Parkinson's disease |
Q91763563 | The Cross-sectional and Longitudinal Associations Between IL-6, IL-10, and TNFα and Cognitive Outcomes in the Mayo Clinic Study of Aging |
Q37652589 | The Neuroprotective Effects of Brazilian Green Propolis on Neurodegenerative Damage in Human Neuronal SH-SY5Y Cells. |
Q24814335 | The microglial "activation" continuum: from innate to adaptive responses |
Q48287927 | The possible role of the immune system in Alzheimer's disease |
Q36266548 | The prospective association of socioeconomic status with C-reactive protein levels in the CARDIA study |
Q35638053 | The role of cholesterol and statins in Alzheimer's disease |
Q33971345 | The role of complement in Alzheimer's disease pathology |
Q42451572 | The toxicity of tumor necrosis factor-α upon cholinergic neurons within the nucleus basalis and the role of norepinephrine in the regulation of inflammation: implications for alzheimer's disease |
Q53343057 | The transcriptional factor LBP-1c/CP2/LSF gene on chromosome 12 is a genetic determinant of Alzheimer's disease. |
Q40055691 | Toll-like receptors 2 and 4 mediate Abeta(1-42) activation of the innate immune response in a human monocytic cell line |
Q38040990 | Treatment strategies targeting amyloid β-protein |
Q48602330 | Up-regulation of the inflammatory cytokines IFN-gamma and IL-12 and down-regulation of IL-4 in cerebral cortex regions of APP(SWE) transgenic mice. |
Q81167475 | Vasoactive intestinal peptide protects against beta-amyloid-induced neurodegeneration by inhibiting microglia activation at multiple levels |
Q36285113 | Wine Flavonoids in Health and Disease Prevention |
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