| scholarly article | Q13442814 |
| P50 | author | Stephen J Perkins | Q59824213 |
| Amy J Osborne | Q59824217 | ||
| P2093 | author name string | Ami Miller | |
| Ruodan Nan | |||
| Jayesh Gor | |||
| Jayesh S Bhatt | |||
| P2860 | cites work | Statistical Validation of Rare Complement Variants Provides Insights into the Molecular Basis of Atypical Hemolytic Uremic Syndrome and C3 Glomerulopathy. | Q52676485 |
| Localization of the third heparin-binding site in the human complement regulator factor H1. | Q53610635 | ||
| Dehydrated but unharmed | Q59050918 | ||
| Ultrastructures and interactions of complement factors H and I | Q67907815 | ||
| Competition for binding sites on C3b by CR1, CR2, MCP, factor B and factor H | Q68414646 | ||
| Identification of a heparin binding domain in the seventh short consensus repeat of complement factor H | Q71860156 | ||
| Identification of the second heparin-binding domain in human complement factor H | Q74412035 | ||
| CHARMM-GUI: a web-based graphical user interface for CHARMM | Q80900573 | ||
| Bivalent and co-operative binding of complement factor H to heparan sulfate and heparin | Q24311571 | ||
| A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration | Q24523983 | ||
| Structure of complement factor H carboxyl-terminus reveals molecular basis of atypical haemolytic uremic syndrome | Q24543850 | ||
| Complement factor H polymorphism in age-related macular degeneration | Q24553334 | ||
| Control of the amplification convertase of complement by the plasma protein beta1H | Q24561671 | ||
| Structural basis for engagement by complement factor H of C3b on a self surface | Q24604385 | ||
| A series of PDB related databases for everyday needs | Q24613221 | ||
| Dual interaction of factor H with C3d and glycosaminoglycans in host-nonhost discrimination by complement | Q24619612 | ||
| Therapeutic targets in age-related macular disease | Q24623107 | ||
| The central portion of factor H (modules 10-15) is compact and contains a structurally deviant CCP module | Q24646284 | ||
| Structure of complement fragment C3b-factor H and implications for host protection by complement regulators | Q24646723 | ||
| Structure of the N-terminal region of complement factor H and conformational implications of disease-linked sequence variations | Q24648540 | ||
| CHARMM: the biomolecular simulation program | Q24658108 | ||
| Structural basis for complement factor H linked age-related macular degeneration | Q24676448 | ||
| CFH haplotypes without the Y402H coding variant show strong association with susceptibility to age-related macular degeneration | Q24681526 | ||
| Human complement C3b inactivator: isolation, characterization, and demonstration of an absolute requirement for the serum protein beta1H for cleavage of C3b and C4b in solution | Q24684822 | ||
| Basic local alignment search tool | Q25938991 | ||
| Folded-back solution structure of monomeric factor H of human complement by synchrotron X-ray and neutron scattering, analytical ultracentrifugation and constrained molecular modelling | Q27632511 | ||
| Structure shows that a glycosaminoglycan and protein recognition site in factor H is perturbed by age-related macular degeneration-linked single nucleotide polymorphism | Q27644071 | ||
| Associative and structural properties of the region of complement factor H encompassing the Tyr402His disease-related polymorphism and its interactions with heparin | Q27644077 | ||
| The regulatory SCR-1/5 and cell surface-binding SCR-16/20 fragments of factor H reveal partially folded-back solution structures and different self-associative properties | Q27649067 | ||
| Electrostatic interactions contribute to the folded-back conformation of wild type human factor H | Q27655807 | ||
| Solution Structure of CCP Modules 10–12 Illuminates Functional Architecture of the Complement Regulator, Factor H | Q27673696 | ||
| Solution structure of a pair of complement modules by nuclear magnetic resonance | Q27731948 | ||
| VMD: visual molecular dynamics | Q27860554 | ||
| Structure validation by Calpha geometry: phi,psi and Cbeta deviation | Q27860657 | ||
| Dictionary of protein secondary structure: pattern recognition of hydrogen-bonded and geometrical features | Q27860675 | ||
| Scalable molecular dynamics with NAMD | Q27860718 | ||
| Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega | Q27860809 | ||
| Size-Distribution Analysis of Macromolecules by Sedimentation Velocity Ultracentrifugation and Lamm Equation Modeling | Q27860847 | ||
| Comparative protein modelling by satisfaction of spatial restraints | Q27860866 | ||
| Host recognition and target differentiation by factor H, a regulator of the alternative pathway of complement | Q28141398 | ||
| An integrated hypothesis that considers drusen as biomarkers of immune-mediated processes at the RPE-Bruch's membrane interface in aging and age-related macular degeneration | Q28190470 | ||
| Complement factor H variant increases the risk of age-related macular degeneration | Q28239239 | ||
| The interactive Factor H-atypical hemolytic uremic syndrome mutation database and website: update and integration of membrane cofactor protein and Factor I mutations with structural models | Q28272816 | ||
| Solution structure of the fifth repeat of factor H: a second example of the complement control protein module | Q28279008 | ||
| Production of biologically active complement factor H in therapeutically useful quantities | Q28300280 | ||
| Complement factor H polymorphism and age-related macular degeneration | Q29614931 | ||
| Statistical potential for assessment and prediction of protein structures | Q29615145 | ||
| Calculation of hydrodynamic properties of globular proteins from their atomic-level structure | Q29620591 | ||
| SCT: a suite of programs for comparing atomistic models with small-angle scattering data | Q30974944 | ||
| X-ray and neutron scattering data and their constrained molecular modeling | Q31134465 | ||
| Atomistic modelling of scattering data in the Collaborative Computational Project for Small Angle Scattering (CCP-SAS). | Q31149216 | ||
| Site-specific N-glycan characterization of human complement factor H. | Q33288780 | ||
| An interactive web database of factor H-associated hemolytic uremic syndrome mutations: insights into the structural consequences of disease-associated mutations | Q33369200 | ||
| Implications of the progressive self-association of wild-type human factor H for complement regulation and disease | Q33377649 | ||
| Tissue-specific host recognition by complement factor H is mediated by differential activities of its glycosaminoglycan-binding regions | Q33405609 | ||
| Evidence for an inflammatory process in age-related macular degeneration gains new support | Q33821745 | ||
| Complement control protein factor H: the good, the bad, and the inadequate. | Q34067107 | ||
| Sedimentation analysis of noninteracting and self-associating solutes using numerical solutions to the Lamm equation | Q34168967 | ||
| Sedimentation velocity analysis of heterogeneous protein-protein interactions: sedimentation coefficient distributions c(s) and asymptotic boundary profiles from Gilbert-Jenkins theory | Q34350597 | ||
| Drusen proteome analysis: an approach to the etiology of age-related macular degeneration. | Q34378842 | ||
| Control of the complement system. | Q34400002 | ||
| Common variation in three genes, including a noncoding variant in CFH, strongly influences risk of age-related macular degeneration | Q34561066 | ||
| A rare penetrant mutation in CFH confers high risk of age-related macular degeneration. | Q35577472 | ||
| Modulation of the alternative complement pathways by beta 1 H globulin | Q36359984 | ||
| Novel function of complement C3d as an autologous helper T-cell target. | Q51897183 | ||
| Oligomeric domain structure of human complement factor H by X-ray and neutron solution scattering. | Q52453534 | ||
| Protein volumes and hydration effects. The calculations of partial specific volumes, neutron scattering matchpoints and 280-nm absorption coefficients for proteins and glycoproteins from amino acid sequences. | Q52641055 | ||
| The solution structures of native and patient monomeric human IgA1 reveal asymmetric extended structures: implications for function and IgAN disease | Q36406807 | ||
| CHARMM-GUI Input Generator for NAMD, GROMACS, AMBER, OpenMM, and CHARMM/OpenMM Simulations Using the CHARMM36 Additive Force Field | Q36461179 | ||
| CHARMM-GUI PDB manipulator for advanced modeling and simulations of proteins containing nonstandard residues. | Q36539936 | ||
| Systematic review and meta-analysis of the association between complement factor H Y402H polymorphisms and age-related macular degeneration | Q36564570 | ||
| Heparan sulfate, including that in Bruch's membrane, inhibits the complement alternative pathway: implications for age-related macular degeneration. | Q36804333 | ||
| Y402H polymorphism of complement factor H affects binding affinity to C-reactive protein | Q36860930 | ||
| Polyanion-induced self-association of complement factor H. | Q37181643 | ||
| Analytical ultracentrifugation: sedimentation velocity and sedimentation equilibrium | Q37264240 | ||
| Identification of three physically and functionally distinct binding sites for C3b in human complement factor H by deletion mutagenesis | Q37306486 | ||
| Genetic control of the alternative pathway of complement in humans and age-related macular degeneration | Q37471769 | ||
| Unravelling protein-protein interactions between complement factor H and C-reactive protein using a multidisciplinary strategy | Q37775642 | ||
| Multiple interactions of complement Factor H with its ligands in solution: a progress report. | Q37780126 | ||
| How random are intrinsically disordered proteins? A small angle scattering perspective | Q37951586 | ||
| Complement factor H-ligand interactions: self-association, multivalency and dissociation constants. | Q37964102 | ||
| Principal component analysis: a method for determining the essential dynamics of proteins | Q38141903 | ||
| The role of complement in age-related macular degeneration: heparan sulphate, a ZIP code for complement factor H? | Q38171012 | ||
| Molecular Interactions between Complement Factor H and Its Heparin and Heparan Sulfate Ligands. | Q38205436 | ||
| New functional and structural insights from updated mutational databases for complement factor H, Factor I, membrane cofactor protein and C3. | Q38304445 | ||
| Prediction of hydrodynamic and other solution properties of rigid proteins from atomic- and residue-level models | Q38492496 | ||
| Arginine side chain interactions and the role of arginine as a gating charge carrier in voltage sensitive ion channels. | Q38582941 | ||
| Combined Monte Carlo/torsion-angle molecular dynamics for ensemble modeling of proteins, nucleic acids and carbohydrates | Q38908424 | ||
| The complement system in age-related macular degeneration: A review of rare genetic variants and implications for personalized treatment | Q39034874 | ||
| Mapping of the domains required for decay acceleration activity of the human factor H-like protein 1 and factor H. | Q39154806 | ||
| Domain structure of human complement C4b extends with increasing NaCl concentration: implications for its regulatory mechanism | Q39293867 | ||
| Constrained solution scattering modelling of human antibodies and complement proteins reveals novel biological insights | Q39757500 | ||
| The disease-protective complement factor H allotypic variant Ile62 shows increased binding affinity for C3b and enhanced cofactor activity | Q39968584 | ||
| Defective complement control of factor H (Y402H) and FHL-1 in age-related macular degeneration | Q40151482 | ||
| Complement factor I and cofactors in control of complement system convertase enzymes | Q40796156 | ||
| Complement factor H binds at two independent sites to C-reactive protein in acute phase concentrations | Q42021566 | ||
| Expression, purification, cocrystallization and preliminary crystallographic analysis of sucrose octasulfate/human complement regulator factor H SCRs 6-8. | Q43167342 | ||
| A tandem mass spectrometer for improved transmission and analysis of large macromolecular assemblies. | Q43939217 | ||
| Complement factor H in AMD: Bridging genetic associations and pathobiology. | Q46022690 | ||
| Bio3d: an R package for the comparative analysis of protein structures. | Q46122078 | ||
| Uncontrolled zinc- and copper-induced oligomerisation of the human complement regulator factor H and its possible implications for function and disease. | Q46270582 | ||
| Functional and structural implications of the complement factor H Y402H polymorphism associated with age-related macular degeneration | Q46761824 | ||
| Association of complement factor H Y402H gene polymorphism with Alzheimer's disease | Q46830145 | ||
| Biosensor-surface plasmon resonance methods for quantitative analysis of biomolecular interactions | Q46928000 | ||
| Crystal structure of a tripartite complex between C3dg, C-terminal domains of factor H and OspE of Borrelia burgdorferi | Q47096479 | ||
| Association of factor H of the alternative pathway of complement with agrin and complement receptor 3 in the Alzheimer's disease brain | Q48435905 | ||
| P433 | issue | 44 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | molecular biology | Q7202 |
| P304 | page(s) | 17166-17187 | |
| P577 | publication date | 2018-11-02 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | Two distinct conformations of factor H regulate discrete complement-binding functions in the fluid phase and at cell surfaces | |
| P478 | volume | 293 |
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