p32 regulates ER stress and lipid homeostasis by down-regulating GCS1 expression

scientific article published on 20 February 2018

p32 regulates ER stress and lipid homeostasis by down-regulating GCS1 expression is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1096/FJ.201701004RR
P932PMC publication ID5998967
P698PubMed publication ID29465311

P2093author name stringYong Liu
Yanping Zhang
Lee M Graves
Koji Itahana
Aiwen Jin
Patrick L Leslie
P2860cites workThe splicing factor-associated protein, p32, regulates RNA splicing by inhibiting ASF/SF2 RNA binding and phosphorylationQ22001546
Oxygen-dependent expression of cytochrome c oxidase subunit 4-2 gene expression is mediated by transcription factors RBPJ, CXXC5 and CHCHD2Q24307974
Isolation, cDNA cloning, and overexpression of a 33-kD cell surface glycoprotein that binds to the globular "heads" of C1qQ24315866
Functional expression of cloned human splicing factor SF2: homology to rna-binding proteins, U1 70K, and drosophila splicing regulatorsQ24317722
Castanospermine inhibits alpha-glucosidase activities and alters glycogen distribution in animalsQ24568239
Endoplasmic reticulum stress and the inflammatory basis of metabolic diseaseQ24633352
Lipid droplets at a glanceQ24646389
p32 protein, a splicing factor 2-associated protein, is localized in mitochondrial matrix and is functionally important in maintaining oxidative phosphorylationQ27935814
Stress-induced phosphorylation and activation of the transcription factor CHOP (GADD153) by p38 MAP KinaseQ28280649
The mitochondrial transporter family SLC25: identification, properties and physiopathologyQ28282100
Regulation of hepatic lipogenesis by the transcription factor XBP1Q28507784
A spectrophotometric assay for glucosidase IQ72547552
Retargeting of the mitochondrial protein p32/gC1Qr to a cytoplasmic compartment and the cell surfaceQ74331022
p32/gC1qR is indispensable for fetal development and mitochondrial translation: importance of its RNA-binding abilityQ28587023
Phospholipid synthesis in a membrane fraction associated with mitochondriaQ28647511
Constitutive role for IRE1α-XBP1 signaling pathway in the insulin-mediated hepatic lipogenic programQ30426645
Mitochondrial p32 protein is a critical regulator of tumor metabolism via maintenance of oxidative phosphorylationQ33705060
Glycosylation, hypogammaglobulinemia, and resistance to viral infectionsQ33789632
Bridging the gap: membrane contact sites in signaling, metabolism, and organelle dynamicsQ33797013
p32 heterozygosity protects against age- and diet-induced obesity by increasing energy expenditureQ33916214
Aberrant lipid metabolism disrupts calcium homeostasis causing liver endoplasmic reticulum stress in obesityQ34181503
A unique mitochondria-associated membrane fraction from rat liver has a high capacity for lipid synthesis and contains pre-Golgi secretory proteins including nascent lipoproteinsQ34325693
The enzymes of neutral lipid synthesisQ34360744
How N-linked oligosaccharides affect glycoprotein folding in the endoplasmic reticulumQ34441056
Chronic enrichment of hepatic endoplasmic reticulum-mitochondria contact leads to mitochondrial dysfunction in obesityQ34449244
Mice deficient in the respiratory chain gene Cox6a2 are protected against high-fat diet-induced obesity and insulin resistanceQ34608360
The unfolded protein response in nutrient sensing and differentiationQ34664763
Mitofusin 2 ablation increases endoplasmic reticulum-mitochondria couplingQ35567148
CHCHD2 inhibits apoptosis by interacting with Bcl-x L to regulate Bax activation.Q35579307
Pharmacological ER stress promotes hepatic lipogenesis and lipid droplet formationQ35747483
The impact of the unfolded protein response on human diseaseQ36062081
ER stress and diseases.Q36731474
Deficiency of α-glucosidase I alters glycoprotein glycosylation and lifespan in Caenorhabditis elegans.Q37154034
Nutritional regulation of the fatty acid synthase promoter in vivo: sterol regulatory element binding protein functions through an upstream region containing a sterol regulatory elementQ37254332
Mitofusin 2 in POMC neurons connects ER stress with leptin resistance and energy imbalance.Q37339111
Regulation of sterol regulatory element binding proteins in livers of fasted and refed miceQ37375695
Endoplasmic reticulum-mitochondria contacts: function of the junctionQ37417736
Endoplasmic reticulum stress, obesity and diabetesQ37926034
MAM (mitochondria-associated membranes) in mammalian cells: lipids and beyondQ38169449
The Lec23 Chinese hamster ovary mutant is a sensitive host for detecting mutations in alpha-glucosidase I that give rise to congenital disorder of glycosylation IIb (CDG IIb).Q38336319
The life cycle of lipid dropletsQ38363818
Mitochondria-Associated Membranes Response to Nutrient Availability and Role in Metabolic DiseasesQ38964888
Adipose-specific deletion of TFAM increases mitochondrial oxidation and protects mice against obesity and insulin resistanceQ39241662
Fatty acid synthesis in liver and adipose tissueQ40156434
Obesity-induced endoplasmic reticulum stress causes chronic inflammation in adipose tissueQ41248481
The role of SREBP-1c in nutritional regulation of lipogenic enzyme gene expressionQ43997258
Targeted deletion of AIF decreases mitochondrial oxidative phosphorylation and protects from obesity and diabetesQ46915798
Acetyl-CoA carboxylase beta gene is regulated by sterol regulatory element-binding protein-1 in liverQ47891691
Obesity: stressing about unfolded proteins.Q53992488
Purification and characterization of trimming glucosidase I from pig liver.Q54346726
P407language of work or nameEnglishQ1860
P304page(s)fj201701004RR
P577publication date2018-02-20
P1433published inFASEB JournalQ520194
P1476titlep32 regulates ER stress and lipid homeostasis by down-regulating GCS1 expression

Reverse relations

Q98205106Porcine reproductive and respiratory syndrome virus infection induces endoplasmic reticulum stress, facilitates virus replication, and contributes to autophagy and apoptosiscites workP2860

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