HDAC5 integrates ER stress and fasting signals to regulate hepatic fatty acid oxidation

scientific article published on 11 December 2017

HDAC5 integrates ER stress and fasting signals to regulate hepatic fatty acid oxidation is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1194/JLR.M080382
P932PMC publication ID5794426
P698PubMed publication ID29229738

P2093author name stringYang Xiao
Chao Zhang
Jian Li
Haiyan He
Bing Luan
Bingxin Xu
Fangfei Guo
Jiamin Yu
Jindong Yao
Junkun Jiang
Sihan Lv
Xinchen Qiu
Zhen-Ning Zhang
P2860cites workActivation of the myocyte enhancer factor-2 transcription factor by calcium/calmodulin-dependent protein kinase-stimulated binding of 14-3-3 to histone deacetylase 5Q24290618
Peroxisome proliferator-activated receptor alpha mediates the adaptive response to fastingQ24563197
Class IIa histone deacetylases are hormone-activated regulators of FOXO and mammalian glucose homeostasisQ42681991
Nonalcoholic fatty liver, steatohepatitis, and the metabolic syndromeQ44385945
Hepatic glucokinase is required for the synergistic action of ChREBP and SREBP-1c on glycolytic and lipogenic gene expressionQ44777483
Glucagon-induced extracellular cAMP regulates hepatic lipid metabolism.Q50996094
Defect in peroxisome proliferator-activated receptor alpha-inducible fatty acid oxidation determines the severity of hepatic steatosis in response to fasting.Q51555809
The CREB coactivator CRTC2 controls hepatic lipid metabolism by regulating SREBP1.Q52661639
A negative feedback loop of ICER and NF-κB regulates TLR signaling in innate immune responses.Q53917688
The many roles of histone deacetylases in development and physiology: implications for disease and therapyQ24628821
A fasting inducible switch modulates gluconeogenesis via activator/coactivator exchangeQ24648525
Analyzing real-time PCR data by the comparative C(T) methodQ28131831
Regulation of hepatic lipogenesis by the transcription factor XBP1Q28507784
Leptin-mediated increases in catecholamine signaling reduce adipose tissue inflammation via activation of macrophage HDAC4Q28508755
Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetesQ28575190
SIK1 is a class II HDAC kinase that promotes survival of skeletal myocytesQ28590015
Regulation of glucose homeostasis through a XBP-1-FoxO1 interactionQ28592129
Histone deacetylase 5 acquires calcium/calmodulin-dependent kinase II responsiveness by oligomerization with histone deacetylase 4Q28592681
The glucagon receptor is required for the adaptive metabolic response to fastingQ28594780
Endocrine regulation of the fasting response by PPARalpha-mediated induction of fibroblast growth factor 21Q29615209
Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetesQ29615503
PPARs and the complex journey to obesityQ29619271
Nuclear receptors and lipid physiology: opening the X-filesQ29619362
PPARalpha: energy combustion, hypolipidemia, inflammation and cancerQ33805104
CREB and the CRTC co-activators: sensors for hormonal and metabolic signalsQ34166530
Regulation of hepatic fatty acid oxidation and ketone body productionQ34248852
Genetic determinants of hepatic steatosis in man.Q34646183
Ca2+ signaling and calcium binding chaperones of the endoplasmic reticulumQ35051255
A hormone-dependent module regulating energy balanceQ35086655
PKA phosphorylation couples hepatic inositol-requiring enzyme 1alpha to glucagon signaling in glucose metabolismQ35229188
Studies of pancreatic alpha cell function in normal and diabetic subjectsQ35576866
Human fatty liver disease: old questions and new insightsQ35588477
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Calcium/calmodulin-dependent protein kinase II links ER stress with Fas and mitochondrial apoptosis pathways.Q37363053
New insights into ER stress-induced insulin resistance.Q38024445
Targeting the unfolded protein response in disease.Q38132652
SIK2 regulates fasting-induced PPARα activity and ketogenesis through p300.Q39064634
Glucagon-induced acetylation of Foxa2 regulates hepatic lipid metabolismQ39193322
HDAC5 Inhibits Hepatic Lipogenic Genes Expression by Attenuating the Transcriptional Activity of Liver X ReceptorQ39403994
Hepatic ATF6 Increases Fatty Acid Oxidation to Attenuate Hepatic Steatosis in Mice Through Peroxisome Proliferator-Activated Receptor α.Q39748140
Pivotal role of calcium/calmodulin-dependent protein kinase II in ER stress-induced apoptosisQ39827850
Insulin modulates gluconeogenesis by inhibition of the coactivator TORC2.Q40084257
Suppression of CRTC2-mediated hepatic gluconeogenesis by TRAF6 contributes to hypoglycemia in septic shockQ40404873
The CREB coactivator CRTC2 links hepatic ER stress and fasting gluconeogenesisQ41791624
The unfolded protein response transducer IRE1α prevents ER stress-induced hepatic steatosisQ41904044
UPR pathways combine to prevent hepatic steatosis caused by ER stress-mediated suppression of transcriptional master regulators.Q42041480
Ectopic expression of glucagon receptor in skeletal muscles improves glucose homeostasis in a mouse model of diabetes.Q42501816
P433issue2
P921main subjectfatty acidQ61476
P304page(s)330-338
P577publication date2017-12-11
P1433published inJournal of Lipid ResearchQ6295449
P1476titleHDAC5 integrates ER stress and fasting signals to regulate hepatic fatty acid oxidation
P478volume59

Reverse relations

cites work (P2860)
Q87973497BMAL1 functions as a cAMP-responsive coactivator of HDAC5 to regulate hepatic gluconeogenesis
Q61803675Epigenomic signatures in liver and blood of Wilson disease patients include hypermethylation of liver-specific enhancers
Q57072853Peroxisome Proliferator Activated Receptor Agonists Modulate Transposable Element Expression in Brain and Liver

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