| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1100823648 |
| P356 | DOI | 10.1186/S40364-018-0120-4 |
| P932 | PMC publication ID | 5800079 |
| P698 | PubMed publication ID | 29441205 |
| P50 | author | Craig T Wallington-Beddoe | Q83771647 |
| Linda Bendall | Q89287832 | ||
| P2093 | author name string | Ken F Bradstock | |
| Daochen Tong | |||
| Vicki Xie | |||
| P2860 | cites work | Sphingosine kinase 1 is a reliable prognostic factor and a novel therapeutic target for uterine cervical cancer | Q27853204 |
| Biological characterization of 3-(2-amino-ethyl)-5-[3-(4-butoxyl-phenyl)-propylidene]-thiazolidine-2,4-dione (K145) as a selective sphingosine kinase-2 inhibitor and anticancer agent | Q28486289 | ||
| Essential role for sphingosine kinases in neural and vascular development | Q28505987 | ||
| RAG-1-deficient mice have no mature B and T lymphocytes | Q28592133 | ||
| Transient expression of the Arf tumor suppressor during male germ cell and eye development in Arf-Cre reporter mice | Q30486791 | ||
| Sphingosine kinase 1: A novel independent prognosis biomarker in hepatocellular carcinoma | Q33598751 | ||
| The expression of sphingosine kinase-1 in head and neck carcinoma | Q33626361 | ||
| Overexpression of sphingosine kinase 1 is associated with salivary gland carcinoma progression and might be a novel predictive marker for adjuvant therapy | Q33693882 | ||
| Pharmacology and antitumor activity of ABC294640, a selective inhibitor of sphingosine kinase-2 | Q33755206 | ||
| Regulation of histone acetylation in the nucleus by sphingosine-1-phosphate. | Q33773569 | ||
| A novel sphingosine kinase inhibitor induces autophagy in tumor cells | Q33861997 | ||
| Inhibition of sphingosine kinase 2 downregulates the expression of c-Myc and Mcl-1 and induces apoptosis in multiple myeloma. | Q34209320 | ||
| Assessment of the effect of sphingosine kinase inhibitors on apoptosis,unfolded protein response and autophagy of T-cell acute lymphoblastic leukemia cells; indications for novel therapeutics | Q34365926 | ||
| Antitumor activity of sphingosine kinase 2 inhibitor ABC294640 and sorafenib in hepatocellular carcinoma xenografts | Q34928923 | ||
| Sphingosine kinase-1 and sphingosine 1-phosphate receptor 2 mediate Bcr-Abl1 stability and drug resistance by modulation of protein phosphatase 2A. | Q35037415 | ||
| Targeting sphingosine kinase 2 (SphK2) by ABC294640 inhibits colorectal cancer cell growth in vitro and in vivo | Q36027371 | ||
| ABC294640, a sphingosine kinase 2 inhibitor, enhances the antitumor effects of TRAIL in non-small cell lung cancer | Q36216032 | ||
| The Sphingosine Kinase 2 Inhibitor ABC294640 Reduces the Growth of Prostate Cancer Cells and Results in Accumulation of Dihydroceramides In Vitro and In Vivo | Q36359489 | ||
| Identification of SPHK1 as a therapeutic target and marker of poor prognosis in cholangiocarcinoma. | Q36414244 | ||
| A selective sphingosine kinase 1 inhibitor integrates multiple molecular therapeutic targets in human leukemia. | Q36835151 | ||
| Sphingosine kinase isoforms as a therapeutic target in endocrine therapy resistant luminal and basal-A breast cancer | Q37637959 | ||
| Oncogenic properties of sphingosine kinases in haematological malignancies. | Q38092176 | ||
| Increased SPHK1 expression is associated with poor prognosis in bladder cancer | Q38394714 | ||
| Clinical significance of sphingosine kinase-1 expression in human astrocytomas progression and overall patient survival | Q38424345 | ||
| Targeting sphingosine kinase 1 induces MCL1-dependent cell death in acute myeloid leukemia | Q38726551 | ||
| Sphingosine 1-phosphate and sphingosine kinases in health and disease: Recent advances | Q38771485 | ||
| Downregulation of Critical Oncogenes by the Selective SK2 Inhibitor ABC294640 Hinders Prostate Cancer Progression | Q38843958 | ||
| Targeting ovarian cancer and chemoresistance through selective inhibition of sphingosine kinase-2 with ABC294640. | Q39097511 | ||
| Sphingosine kinase 2 deficient tumor xenografts show impaired growth and fail to polarize macrophages towards an anti-inflammatory phenotype | Q39823174 | ||
| Hypoxia enhances sphingosine kinase 2 activity and provokes sphingosine-1-phosphate-mediated chemoresistance in A549 lung cancer cells. | Q39880133 | ||
| Sphingosine kinase isoforms regulate oxaliplatin sensitivity of human colon cancer cells through ceramide accumulation and Akt activation. | Q39880179 | ||
| Sphingosine kinase 1 is associated with gastric cancer progression and poor survival of patients | Q39881982 | ||
| Implications of sphingosine kinase 1 expression level for the cellular sphingolipid rheostat: relevance as a marker for daunorubicin sensitivity of leukemia cells | Q40011666 | ||
| Involvement of sphingosine kinase 2 in p53-independent induction of p21 by the chemotherapeutic drug doxorubicin | Q40059172 | ||
| Sphingosine kinase-1 expression correlates with poor survival of patients with glioblastoma multiforme: roles of sphingosine kinase isoforms in growth of glioblastoma cell lines | Q40384186 | ||
| Sphingosine kinase 2 inhibition synergises with bortezomib to target myeloma by enhancing endoplasmic reticulum stress. | Q41279386 | ||
| Mobilization studies in mice deficient in sphingosine kinase 2 support a crucial role of the plasma level of sphingosine-1-phosphate in the egress of hematopoietic stem progenitor cells. | Q42371558 | ||
| Microarray analysis of altered sphingolipid metabolism reveals prognostic significance of sphingosine kinase 1 in breast cancer. | Q42638803 | ||
| CDKN2A, CDKN2B, and MTAP gene dosage permits precise characterization of mono- and bi-allelic 9p21 deletions in childhood acute lymphoblastic leukemia | Q44379464 | ||
| Potentiating effects of RAD001 (Everolimus) on vincristine therapy in childhood acute lymphoblastic leukemia | Q46131736 | ||
| Sphingosine kinase-1 is a downstream regulator of imatinib-induced apoptosis in chronic myeloid leukemia cells | Q46653570 | ||
| Prognostic significance of sphingosine kinase 2 expression in non-small cell lung cancer | Q47851906 | ||
| Using MS-MLPA as an efficient screening tool for detecting 9p21 abnormalities in pediatric acute lymphoblastic leukemia. | Q51018567 | ||
| Down-regulation of sphingosine kinase 2 (SphK2) increases the effects of all-trans-retinoic acid (ATRA) on colon cancer cells. | Q52998128 | ||
| Tumor spectrum in ARF-deficient mice. | Q53423902 | ||
| Sphingosine kinase 2 promotes acute lymphoblastic leukemia by enhancing MYC expression. | Q54363475 | ||
| A Phase I Study of ABC294640, a First-in-Class Sphingosine Kinase-2 Inhibitor, in Patients with Advanced Solid Tumors. | Q55001442 | ||
| The incidence of chromosome 9p21 abnormalities and deletions of tumor suppressor genes p15(INK4b)/p16(INK4a)/p14(ARF) in patients with acute lymphoblastic leukemia | Q73370235 | ||
| Alterations of ceramide/sphingosine 1-phosphate rheostat involved in the regulation of resistance to imatinib-induced apoptosis in K562 human chronic myeloid leukemia cells | Q79782164 | ||
| P921 | main subject | leukemia | Q29496 |
| lymphoblastic leukemia | Q18553852 | ||
| P304 | page(s) | 6 | |
| P577 | publication date | 2018-02-05 | |
| P1433 | published in | Biomarker Research | Q27724844 |
| P1476 | title | Sphingosine kinase 2 supports the development of BCR/ABL-independent acute lymphoblastic leukemia in mice | |
| P478 | volume | 6 |
| Q89987678 | Sphingosine kinase-2 is overexpressed in large granular lymphocyte leukaemia and promotes survival through Mcl-1 | cites work | P2860 |
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