Human iPSC-Derived Endothelial Cells and Microengineered Organ-Chip Enhance Neuronal Development.

scientific article published on 21 March 2018

Human iPSC-Derived Endothelial Cells and Microengineered Organ-Chip Enhance Neuronal Development. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/J.STEMCR.2018.02.012
P932PMC publication ID5998748
P698PubMed publication ID29576540

P50authorRitchie HoQ57232730
Marlesa GodoyQ86664870
P2093author name stringClive N Svendsen
Gad Vatine
Geraldine A Hamilton
Amanda Meyer
Dhruv Sareen
Dylan West
Berhan Mandefro
Samuel Sances
Alex Laperle
Chris Hinojosa
Norman Wen
Paul S Kay
Seigo Hatata
P2860cites workDorsal-ventral patterning of the spinal cord requires Gli3 transcriptional repressor activityQ24682634
Wiring the Vascular Network with Neural Cues: A CNS PerspectiveQ26800182
Subtype-specific plasticity of inhibitory circuits in motor cortex during motor learning.Q27312283
An acetylcholine-activated microcircuit drives temporal dynamics of cortical activityQ27312520
Contributions of microbiome and mechanical deformation to intestinal bacterial overgrowth and inflammation in a human gut-on-a-chipQ27316911
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resourcesQ27860739
Modeling ALS with motor neurons derived from human induced pluripotent stem cellsQ28076026
Molecular and cellular development of spinal cord locomotor circuitryQ28082501
Requirement for LIM homeobox gene Isl1 in motor neuron generation reveals a motor neuron-dependent step in interneuron differentiationQ28273468
Pax6 controls progenitor cell identity and neuronal fate in response to graded Shh signalingQ28571762
Thrombospondins are astrocyte-secreted proteins that promote CNS synaptogenesisQ28574686
Cerebral organoids model human brain development and microcephalyQ28973619
Neuronal specification in the spinal cord: inductive signals and transcriptional codesQ29616039
Vascular niche for adult hippocampal neurogenesisQ29619395
Nuclear RNA-seq of single neurons reveals molecular signatures of activationQ30276962
Probing embryonic stem cell autocrine and paracrine signaling using microfluidicsQ33647797
ALS-causing SOD1 mutants generate vascular changes prior to motor neuron degenerationQ33954016
Reconstituting organ-level lung functions on a chipQ34122591
An RNA-sequencing transcriptome and splicing database of glia, neurons, and vascular cells of the cerebral cortex.Q34123789
Coordinated interaction of neurogenesis and angiogenesis in the adult songbird brain.Q34135656
Emergence of patterned activity in the developing zebrafish spinal cordQ34242855
The NIH Roadmap Epigenomics Program data resourceQ34300879
Maturation of spinal motor neurons derived from human embryonic stem cellsQ34339658
Delayed disease onset and extended survival in the SOD1G93A rat model of amyotrophic lateral sclerosis after suppression of mutant SOD1 in the motor cortexQ34983540
Stimulation of GABA-induced Ca2+ influx enhances maturation of human induced pluripotent stem cell-derived neuronsQ35053840
Cyclin D1 promotes neurogenesis in the developing spinal cord in a cell cycle-independent mannerQ35105147
Astrocytes from familial and sporadic ALS patients are toxic to motor neuronsQ35206666
Generation and expansion of highly pure motor neuron progenitors from human pluripotent stem cellsQ35222288
HD iPSC-derived neural progenitors accumulate in culture and are susceptible to BDNF withdrawal due to glutamate toxicityQ35585297
Human pluripotent stem cell-derived neural constructs for predicting neural toxicityQ36155259
Hyperactive somatostatin interneurons contribute to excitotoxicity in neurodegenerative disorders.Q36739537
Early Somatostatin Interneuron Connectivity Mediates the Maturation of Deep Layer Cortical Circuits.Q36883553
Neurovascular signalling defects in neurodegenerationQ37078102
Cell lineages and early patterns of embryonic CNS vascularizationQ37186236
A dynamic in vivo-like organotypic blood-brain barrier model to probe metastatic brain tumors.Q37405615
Cellular observations enabled by microculture: paracrine signaling and population demographicsQ37469001
A retinoic acid-enhanced, multicellular human blood-brain barrier model derived from stem cell sources.Q37598924
Brain microvascular endothelial cells resist elongation due to curvature and shear stress.Q37702743
Getting neural circuits into shape with semaphorinsQ38034907
The role of semaphorins and their receptors in vascular development and cancer.Q38082866
Novel insights into the development and maintenance of the blood-brain barrierQ38192912
Pluripotent stem cells in disease modelling and drug discoveryQ38714328
Somatostatin-expressing neurons in cortical networks.Q38844277
Induced pluripotent stem cell technology: a decade of progressQ39040578
BBB on chip: microfluidic platform to mechanically and biochemically modulate blood-brain barrier function.Q39284045
Understanding microchannel culture: parameters involved in soluble factor signalingQ40125971
Endothelial cells stimulate self-renewal and expand neurogenesis of neural stem cellsQ40570664
ALS disrupts spinal motor neuron maturation and aging pathways within gene co-expression networksQ40968548
Automated quantification of neuronal networks and single-cell calcium dynamics using calcium imaging.Q41356153
Somatostatin enhances nerve growth factor-induced neurite outgrowth in PC12 cellsQ41454963
C9orf72 is required for proper macrophage and microglial function in miceQ42364302
Expression pattern of NeuN and GFAP during human fetal spinal cord developmentQ42476051
Muscle-conditioned media and cAMP promote survival and neurite outgrowth of adult spinal cord motor neurons.Q43277866
Assembly of functionally integrated human forebrain spheroidsQ43487488
Modeling Psychomotor Retardation using iPSCs from MCT8-Deficient Patients Indicates a Prominent Role for the Blood-Brain Barrier.Q46205341
Microfluidic blood-brain barrier model provides in vivo-like barrier properties for drug permeability screening.Q48629588
Organoid and Organ-On-A-Chip Systems: New Paradigms for Modeling Neurological and Gastrointestinal Disease.Q49569055
Microfluidic organs-on-chips.Q51510970
Formation and characterisation of neuromuscular junctions between hiPSC derived motoneurons and myotubes.Q51816582
Development of innervation of skeletal muscle fibers in man: relation to acetylcholine receptors.Q52224054
P4510describes a project that usesImageJQ1659584
P433issue4
P304page(s)1222-1236
P577publication date2018-03-22
P1433published inStem Cell ReportsQ27725039
P1476titleHuman iPSC-Derived Endothelial Cells and Microengineered Organ-Chip Enhance Neuronal Development.
P478volume10

Reverse relations

cites work (P2860)
Q90733769Brain-on-a-chip: A history of development and future perspective
Q88732189Developmentally inspired human 'organs on chips'
Q64900124Hypoxia-enhanced Blood-Brain Barrier Chip recapitulates human barrier function and shuttling of drugs and antibodies.
Q90110358Multi-lineage Human iPSC-Derived Platforms for Disease Modeling and Drug Discovery
Q97644327Organ-On-Chip Technology: The Future of Feto-Maternal Interface Research?
Q91409376Organs-on-Chips in Clinical Pharmacology: Putting the Patient Into the Center of Treatment Selection and Drug Development
Q99350419Organs-on-chips: into the next decade
Q93160159Recent advances in human iPSC-derived models of the blood-brain barrier
Q92979190Robotic fluidic coupling and interrogation of multiple vascularized organ chips
Q101403284Using multi-organ culture systems to study Parkinson's disease

Search more.