Pitavastatin inhibits lysophosphatidic acid-induced proliferation and monocyte chemoattractant protein-1 expression in aortic smooth muscle cells by suppressing Rac-1-mediated reactive oxygen species generation.

scientific article published on 14 November 2006

Pitavastatin inhibits lysophosphatidic acid-induced proliferation and monocyte chemoattractant protein-1 expression in aortic smooth muscle cells by suppressing Rac-1-mediated reactive oxygen species generation. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.VPH.2006.11.002
P698PubMed publication ID17178255

P2093author name stringUtako Kaneyuki
Masamichi Kojiro
Seiya Kato
Seiya Okuda
Sho-ichi Yamagishi
Seiji Ueda
Koichi Oshima
Junko Yoshimura
Ayako Hayashida
Ryo Shibata
Toshiko Fujimura
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Pigment epithelium-derived factor prevents advanced glycation end products-induced monocyte chemoattractant protein-1 production in microvascular endothelial cells by suppressing intracellular reactive oxygen species generationQ44355887
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Subtype-selective antagonists of lysophosphatidic Acid receptors inhibit platelet activation triggered by the lipid core of atherosclerotic plaquesQ44529184
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Regulation of mitogen-activated protein kinase cascades by low density lipoprotein and lysophosphatidic acidQ44859407
Inhibitory efficacy of pitavastatin on the early inflammatory response and neointimal thickening in a porcine coronary after stentingQ44890789
Pigment epithelium-derived factor inhibits TNF-alpha-induced interleukin-6 expression in endothelial cells by suppressing NADPH oxidase-mediated reactive oxygen species generation.Q44994254
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Pigment epithelium-derived factor (PEDF) blocks angiotensin II signaling in endothelial cells via suppression of NADPH oxidase: a novel anti-oxidative mechanism of PEDF.Q46450720
Decreased lesion formation in CCR2-/- mice reveals a role for chemokines in the initiation of atherosclerosisQ46897070
Convergence of redox-sensitive and mitogen-activated protein kinase signaling pathways in tumor necrosis factor-alpha-mediated monocyte chemoattractant protein-1 induction in vascular smooth muscle cellsQ73435144
Platelet-derived growth factor-stimulated superoxide anion production modulates activation of transcription factor NF-kappaB and expression of monocyte chemoattractant protein 1 in human aortic smooth muscle cellsQ73804432
Coordinate regulation of matrix metalloproteinase-1 and tissue inhibitor of metalloproteinase-1 expression in human vascular smooth muscle cellsQ74327226
Stimulation of a vascular smooth muscle cell NAD(P)H oxidase by thrombin. Evidence that p47(phox) may participate in forming this oxidase in vitro and in vivoQ77955201
Atherosclerosis — An Inflammatory DiseaseQ26776972
Vascular smooth muscle migration and proliferation in response to lysophosphatidic acid (LPA) is mediated by LPA receptors coupling to GqQ28566091
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Characterization of rac and cdc42 activation in chemoattractant-stimulated human neutrophils using a novel assay for active GTPasesQ29618793
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Monocyte chemoattractant protein-1 in human atheromatous plaquesQ34203056
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Lysophospholipids and the cardiovascular systemQ34691544
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Role of oxidative stress in atherosclerosisQ35088521
Minodronate, a newly developed nitrogen-containing bisphosphonate, suppresses melanoma growth and improves survival in nude mice by blocking vascular endothelial growth factor signalingQ35103539
Rac regulates cardiovascular superoxide through diverse molecular interactions: more than a binary GTP switchQ35212986
Reactive oxygen species in the vasculature: molecular and cellular mechanismsQ35569201
Vascular NADPH oxidases: molecular mechanisms of activation.Q35994483
Lysophospholipids increase ICAM-1 expression in HUVEC through a Gi- and NF-kappaB-dependent mechanismQ40528453
NK-104, a newly developed HMG-CoA reductase inhibitor, suppresses neointimal thickening by inhibiting smooth muscle cell growth and fibronectin production in balloon-injured rabbit carotid arteryQ41021554
Lysophosphatidic acid and intracellular signalling in vascular smooth muscle cellsQ42437572
P433issue4
P921main subjectreactive oxygen speciesQ424361
P1104number of pages7
P304page(s)286-292
P577publication date2006-11-14
P1433published inVascular PharmacologyQ7916446
P1476titlePitavastatin inhibits lysophosphatidic acid-induced proliferation and monocyte chemoattractant protein-1 expression in aortic smooth muscle cells by suppressing Rac-1-mediated reactive oxygen species generation.
P478volume46

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