Literature mining for the discovery of hidden connections between drugs, genes and diseases

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Literature mining for the discovery of hidden connections between drugs, genes and diseases is …
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scholarly articleQ13442814

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P8978DBLP publication IDjournals/ploscb/FrijtersVSSVA10
P356DOI10.1371/JOURNAL.PCBI.1000943
P3181OpenCitations bibliographic resource ID2266224
P932PMC publication ID2944780
P698PubMed publication ID20885778
P5875ResearchGate publication ID47157413

P50authorWynand AlkemaQ55545159
P2093author name stringJacob de Vlieg
Ruben Smeets
René van Schaik
Raoul Frijters
Marianne van Vugt
P2860cites workExtending the mutual information measure to rank inferred literature relationshipsQ24792665
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Monocyte and macrophage heterogeneityQ29547438
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Can the pharmaceutical industry reduce attrition rates?Q29616077
Literature mining for the biologist: from information retrieval to biological discoveryQ30002370
Compactin and simvastatin, but not pravastatin, induce bone morphogenetic protein-2 in human osteosarcoma cellsQ30871041
CoPub: a literature-based keyword enrichment tool for microarray data analysisQ31153846
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Damnacanthal is a highly potent, selective inhibitor of p56lck tyrosine kinase activityQ34294649
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5-HT1A-receptor subtype mediates the effect of fluvoxamine, a selective serotonin reuptake inhibitor, on marble-burying behavior in miceQ71574445
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Monocyte chemoattractant protein-1 induces scavenger receptor expression and monocyte differentiation into foam cellsQ73389643
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Dephostatin, a novel protein tyrosine phosphatase inhibitor produced by Streptomyces. I. Taxonomy,isolation, and characterization.Q78421489
Association of an A/C single nucleotide polymorphism in programmed cell death-ligand 1 gene with Graves' disease in Japanese patientsQ80825538
Interaction of CTLA-4 (CD152) with CD80 or CD86 inhibits human T-cell activationQ34506039
Biomarkers, validation and pharmacokinetic-pharmacodynamic modellingQ35213462
The computational analysis of scientific literature to define and recognize gene expression clustersQ35222434
Adhesion mechanisms regulating the migration of monocytesQ35790360
Using text analysis to identify functionally coherent gene groupsQ35806045
Effects of 5-HT uptake inhibitors, agonists and antagonists on the burying of harmless objects by mice; a putative test for anxiolytic agentsQ35871873
Clinical experience with dual action antidepressants in different chronic pain syndromesQ35892373
Systems biology in drug discoveryQ35911464
Can cell systems biology rescue drug discovery?Q36138342
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Systems biology, metabolic modelling and metabolomics in drug discovery and developmentQ36665669
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Overview of BioCreative II gene normalizationQ36920188
The thyrotropin receptor in Graves' diseaseQ36932727
Strategic approach to fit-for-purpose biomarkers in drug developmentQ36971800
Adipose tissue dysfunction in obesity, diabetes, and vascular diseasesQ37262617
Role of peroxisome proliferator-activated receptor-gamma in maintenance of the characteristics of mature 3T3-L1 adipocytesQ38287702
Extracting human protein interactions from MEDLINE using a full-sentence parserQ38423132
Knowledge discovery by automated identification and ranking of implicit relationshipsQ38423824
Literature-based compound profiling: application to toxicogenomicsQ38514958
Gene annotation from scientific literature using mappings between keyword systemsQ38522068
Using ARROWSMITH: a computer-assisted approach to formulating and assessing scientific hypothesesQ38548869
Induction of normal phenotypes in ras-transformed cells by damnacanthal from Morinda citrifoliaQ39068580
Fish-oil dietary supplementation in patients with Raynaud's phenomenon: a double-blind, controlled, prospective studyQ39274596
Induction of heme oxygenase-1 inhibits monocyte chemoattractant protein-1 mRNA expression in U937 cellsQ40317306
Pitavastatin downregulates expression of the macrophage type B scavenger receptor, CD36.Q40588956
Automatic extraction of keywords from scientific text: application to the knowledge domain of protein familiesQ40843917
PPARgamma activation induces the expression of the adipocyte fatty acid binding protein gene in human monocytesQ40939045
Dephostatin, a novel protein tyrosine phosphatase inhibitor produced by Streptomyces. I. Taxonomy, isolation, and characterizationQ41531489
Anti-adipogenic action of pitavastatin occurs through the coordinate regulation of PPARgamma and Pref-1 expressionQ41591074
Peroxisome Proliferator Activated Receptor γ, CCAAT/ Enhancer-binding Protein α, and Cell Cycle Status Regulate the Commitment to Adipocyte DifferentiationQ42796360
Both wortmannin and simvastatin inhibit the adipogenesis in 3T3-L1 cells during the late phase of differentiationQ42810681
The effect of statins on mRNA levels of genes related to inflammation, coagulation, and vascular constriction in HUVEC. Human umbilical vein endothelial cellsQ44134020
Functional expression of the norepinephrine transporter in cultured rat astrocytesQ44251293
Milnacipran: a comparative analysis of human monoamine uptake and transporter binding affinityQ44742917
CTLA-4 gene A-G polymorphism and childhood Graves' diseaseQ44807674
Effectiveness of milnacipran for the treatment of chronic pain: a case seriesQ45189016
The applications of biomarkers in early clinical drug development to improve decision-making processesQ45372315
Effects of the serotonin and noradrenaline reuptake inhibitor (SNRI) milnacipran on marble burying behavior in miceQ46867584
Evidence for linkage disequilibrium between serotonin transporter protein gene (SLC6A4) and obsessive compulsive disorderQ47806910
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Association study between the 1287 A/G exonic polymorphism of the norepinephrine transporter (NET) gene and obsessive-compulsive disorder in a Brazilian sampleQ51915444
Using statistical and knowledge-based approaches for literature-based discoveryQ51953854
Improving literature based discovery support by genetic knowledge integration.Q52006778
Genes, themes and microarrays: using information retrieval for large-scale gene analysisQ52074402
Tag SNP screening of the PDCD1 gene for association with Graves' diseaseQ53554417
Pitavastatin inhibits lysophosphatidic acid-induced proliferation and monocyte chemoattractant protein-1 expression in aortic smooth muscle cells by suppressing Rac-1-mediated reactive oxygen species generationQ53582013
A literature network of human genes for high-throughput analysis of gene expressionQ56225641
Analysis of the role of negative T cell costimulatory pathways in CD4 and CD8 T cell-mediated alloimmune responses in vivoQ56902821
CTLA4 gene and Graves' disease: association of Graves' disease with the CTLA4 exon 1 and intron 1 polymorphisms, but not with the promoter polymorphismQ56903893
An interactive system for finding complementary literatures: a stimulus to scientific discoveryQ57372877
Fish oil, Raynaud's syndrome, and undiscovered public knowledgeQ69703977
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue9
P407language of work or nameEnglishQ1860
P304page(s)e1000943
P577publication date2010-09-23
P1433published inPLOS Computational BiologyQ2635829
P1476titleLiterature mining for the discovery of hidden connections between drugs, genes and diseases
P478volume6

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