| scholarly article | Q13442814 |
| P50 | author | Maria A Burnatowska-Hledin | Q96246337 |
| P2093 | author name string | Michael Short | |
| Gabriel A Marquez | |||
| Michael P Hledin | |||
| Abigayle Schnell | |||
| Bryan Kunkler | |||
| Caitlin Ploch | |||
| Daniel Salamango | |||
| David Grossens | |||
| Julie Madden | |||
| Shirley Dean | |||
| Zachary J DeBruine | |||
| P2860 | cites work | Identification of a primary target of thalidomide teratogenicity | Q24302178 |
| Identification and analysis of expression of human VACM-1, a cullin gene family member located on chromosome 11q22-23 | Q24320339 | ||
| Characterization of NEDD8, a developmentally down-regulated ubiquitin-like protein | Q24322977 | ||
| Microvessel overexpression of aquaporin 1 parallels bone marrow angiogenesis in patients with active multiple myeloma | Q61876285 | ||
| Adenovirus E4orf6 assembles with Cullin5-ElonginB-ElonginC E3 ubiquitin ligase through an HIV/SIV Vif-like BC-box to regulate p53 | Q64377210 | ||
| E3 ubiquitin ligases as regulators of membrane protein trafficking and degradation | Q36121124 | ||
| Multimodal activation of the ubiquitin ligase SCF by Nedd8 conjugation | Q37101488 | ||
| Regulation of Hsp90 client proteins by a Cullin5-RING E3 ubiquitin ligase | Q37453413 | ||
| Thalidomide-analogue biology: immunological, molecular and epigenetic targets in cancer therapy. | Q38074017 | ||
| CUL2 is required for the activity of hypoxia-inducible factor and vasculogenesis | Q38868654 | ||
| Inhibition of NEDD8-activating enzyme: a novel approach for the treatment of acute myeloid leukemia. | Q39732225 | ||
| Restriction of Src activity by Cullin-5 | Q39894835 | ||
| Granulocytic differentiation of HL-60 promyelocytic leukemia cells is associated with increased expression of Cul5. | Q39899501 | ||
| Thalidomide induces limb deformities by perturbing the Bmp/Dkk1/Wnt signaling pathway | Q40174117 | ||
| Thalidomide downregulates angiogenic genes in bone marrow endothelial cells of patients with active multiple myeloma. | Q40412896 | ||
| The effect of thalidomide in chicken embryos | Q41994803 | ||
| Expression of aquaporin 1 in primary renal tumors: a prognostic indicator for clear-cell renal cell carcinoma | Q43880715 | ||
| Thalidomide affects the skeletal system of young rats. | Q45898683 | ||
| High cereblon expression is associated with better survival in patients with newly diagnosed multiple myeloma treated with thalidomide maintenance. | Q45910770 | ||
| Impairment of angiogenesis and cell migration by targeted aquaporin-1 gene disruption. | Q46588165 | ||
| Zebrafish cul4a, but not cul4b, modulates cardiac and forelimb development by upregulating tbx5a expression. | Q47073820 | ||
| Heterogeneous expression of the aquaporin 1 (AQP1) water channel in tumors of the prostate, breast, ovary, colon and lung: a study using high density multiple human tumor tissue microarrays. | Q48943250 | ||
| cul-1 is required for cell cycle exit in C. elegans and identifies a novel gene family | Q24336422 | ||
| Thalidomide is an inhibitor of angiogenesis | Q24563363 | ||
| Thalidomide induces limb defects by preventing angiogenic outgrowth during early limb formation | Q24653215 | ||
| Cullin 5 regulates Dab1 protein levels and neuron positioning during cortical development | Q24672124 | ||
| Targeted disruption of p185/Cul7 gene results in abnormal vascular morphogenesis | Q24680360 | ||
| Analysis of CUL-5 expression in breast epithelial cells, breast cancer cell lines, normal tissues and tumor tissues | Q24806313 | ||
| Cdc53p acts in concert with Cdc4p and Cdc34p to control the G1-to-S-phase transition and identifies a conserved family of proteins | Q27933764 | ||
| Function and regulation of cullin-RING ubiquitin ligases | Q28131707 | ||
| Covalent modification of all members of human cullin family proteins by NEDD8 | Q28140243 | ||
| VACM-1, a cul-5 gene, inhibits cellular growth by a mechanism that involves MAPK and p53 signaling pathways | Q28201553 | ||
| Expression of VACM-1 protein in cultured rat adrenal endothelial cells is linked to the cell cycle | Q28202165 | ||
| Induction of APOBEC3G Ubiquitination and Degradation by an HIV-1 Vif-Cul5-SCF Complex | Q28210666 | ||
| T47D breast cancer cell growth is inhibited by expression of VACM-1, a cul-5 gene | Q28265603 | ||
| Expression cloning of an AVP-activated, calcium-mobilizing receptor from rabbit kidney medulla | Q28293389 | ||
| VACM-1 receptor is specifically expressed in rabbit vascular endothelium and renal collecting tubule | Q28296762 | ||
| The myeloma drug lenalidomide promotes the cereblon-dependent destruction of Ikaros proteins | Q28303081 | ||
| Lenalidomide causes selective degradation of IKZF1 and IKZF3 in multiple myeloma cells | Q28303091 | ||
| Thalidomide inhibits the replication of human immunodeficiency virus type 1 | Q28378516 | ||
| Expression of VACM-1/cul5 mutant in endothelial cells induces MAPK phosphorylation and maspin degradation and converts cells to the angiogenic phenotype | Q28578323 | ||
| Degradation of p53 by adenovirus E4orf6 and E1B55K proteins occurs via a novel mechanism involving a Cullin-containing complex | Q29041391 | ||
| An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer | Q29616732 | ||
| Thalidomide attenuates nitric oxide mediated angiogenesis by blocking migration of endothelial cells | Q33238514 | ||
| Polymorphisms of CUL5 are associated with CD4+ T cell loss in HIV-1 infected individuals | Q33270513 | ||
| Thalidomide-induced limb defects: resolving a 50-year-old puzzle | Q33348200 | ||
| E3 ubiquitin ligase Cullin-5 modulates multiple molecular and cellular responses to heat shock protein 90 inhibition in human cancer cells | Q33606911 | ||
| Thalidomide inhibits inflammatory and angiogenic activation of human intestinal microvascular endothelial cells (HIMEC). | Q33655628 | ||
| Phosphorylation of VACM-1/Cul5 by protein kinase A regulates its neddylation and antiproliferative effect | Q33717656 | ||
| Regulation of Apobec3F and human immunodeficiency virus type 1 Vif by Vif-Cul5-ElonB/C E3 ubiquitin ligase | Q33908716 | ||
| MicroRNA-19a and -19b regulate cervical carcinoma cell proliferation and invasion by targeting CUL5. | Q34031832 | ||
| VACM-1/cul5 expression in vascular tissue in vivo is induced by water deprivation and its expression in vitro regulates aquaporin-1 concentrations | Q34031947 | ||
| Cereblon expression is required for the antimyeloma activity of lenalidomide and pomalidomide. | Q34210005 | ||
| ASB2 is an Elongin BC-interacting protein that can assemble with Cullin 5 and Rbx1 to reconstitute an E3 ubiquitin ligase complex | Q34375157 | ||
| Analysis of 11q22-q23 deletion target genes in B-cell chronic lymphocytic leukaemia: evidence for a pathogenic role of NPAT, CUL5, and PPP2R1B. | Q34621297 | ||
| XRab40 and XCullin5 form a ubiquitin ligase complex essential for the noncanonical Wnt pathway | Q35941534 | ||
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P433 | issue | 5 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | thalidomide | Q203174 |
| P304 | page(s) | e0196760 | |
| P577 | publication date | 2018-05-10 | |
| P1433 | published in | PLOS One | Q564954 |
| P1476 | title | CUL5 is required for thalidomide-dependent inhibition of cellular proliferation. | |
| P478 | volume | 13 |
| Q60913826 | Cullin 5 is a novel candidate tumor suppressor in renal cell carcinoma involved in the maintenance of genome stability |
| Q90653983 | ERp29 counteracts the suppression of malignancy mediated by endoplasmic reticulum stress and promotes the metastasis of colorectal cancer |
| Q90482001 | The functions and properties of cullin-5, a potential therapeutic target for cancers |
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