scholarly article | Q13442814 |
P50 | author | Susana Kalko | Q41049953 |
Sandra Rebuffat | Q56523945 | ||
Ainhoa García | Q80455186 | ||
P2093 | author name string | Joan J Guinovart | |
Ramon Gomis | |||
Deborah J Burks | |||
Joana Moitinho Oliveira | |||
Rosa Gasa | |||
Delia Zafra | |||
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GASDERMIN, suppressed frequently in gastric cancer, is a target of LMO1 in TGF-beta-dependent apoptotic signalling | Q24304350 | ||
Disruption of IRS-2 causes type 2 diabetes in mice | Q24316112 | ||
Dysregulation of insulin receptor substrate 2 in beta cells and brain causes obesity and diabetes | Q24564844 | ||
Tungstate reduces the expression of gluconeogenic enzymes in STZ rats | Q27325843 | ||
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Exploration, normalization, and summaries of high density oligonucleotide array probe level data | Q27861098 | ||
Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms | Q28137802 | ||
The IRS-signalling system: a network of docking proteins that mediate insulin action | Q28272481 | ||
Cidea-deficient mice have lean phenotype and are resistant to obesity | Q28504440 | ||
Targeted disruption of the Chop gene delays endoplasmic reticulum stress-mediated diabetes | Q28506402 | ||
Tungstate is an effective antidiabetic agent in streptozotocin-induced diabetic rats: a long-term study | Q28564460 | ||
Role of IGFBP-3 in the regulation of β-cell mass during obesity: adipose tissue/β-cell cross talk | Q28566031 | ||
Rank products: a simple, yet powerful, new method to detect differentially regulated genes in replicated microarray experiments | Q29616371 | ||
Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes | Q29619192 | ||
The role of insulin receptor substrate 2 in hypothalamic and beta cell function. | Q30475796 | ||
Molecular mechanisms of tungstate-induced pancreatic plasticity: a transcriptomics approach. | Q33498114 | ||
Inhibition of PTP1B restores IRS1-mediated hepatic insulin signaling in IRS2-deficient mice | Q33688527 | ||
IRS proteins and beta-cell function | Q34197331 | ||
Pdx1 restores beta cell function in Irs2 knockout mice | Q34791297 | ||
Differential regulation of CHOP-10/GADD153 gene expression by MAPK signaling in pancreatic beta-cells. | Q35880276 | ||
Five stages of evolving beta-cell dysfunction during progression to diabetes | Q35961960 | ||
Relationship between beta-cell mass and diabetes onset. | Q36034329 | ||
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Beta cell apoptosis in diabetes | Q37424013 | ||
Targeting β-Cell Function Early in the Course of Therapy for Type 2 Diabetes Mellitus | Q37782506 | ||
ERK1/2 MAP kinases: structure, function, and regulation | Q38008550 | ||
Loss of ARNT/HIF1beta mediates altered gene expression and pancreatic-islet dysfunction in human type 2 diabetes | Q38322289 | ||
Suppression of FoxO1/cell death-inducing DNA fragmentation factor α-like effector A (Cidea) axis protects mouse β-cells against palmitic acid-induced apoptosis | Q39468503 | ||
cAMP promotes pancreatic beta-cell survival via CREB-mediated induction of IRS2. | Q39895683 | ||
Calcium elevation in mouse pancreatic beta cells evoked by extracellular human islet amyloid polypeptide involves activation of the mechanosensitive ion channel TRPV4. | Q39946656 | ||
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Exendin-4 uses Irs2 signaling to mediate pancreatic beta cell growth and function | Q40354183 | ||
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Molybdate and tungstate act like vanadate on glucose metabolism in isolated hepatocytes | Q42150877 | ||
The antidiabetic agent sodium tungstate activates glycogen synthesis through an insulin receptor-independent pathway. | Q44553715 | ||
Stable and functional regeneration of pancreatic beta-cell population in nSTZ-rats treated with tungstate | Q44767287 | ||
Sodium tungstate activates glycogen synthesis through a non-canonical mechanism involving G-proteins | Q44807995 | ||
Pancreatic remodeling: beta-cell apoptosis, proliferation and neogenesis, and the measurement of beta-cell mass and of individual beta-cell size. | Q45979032 | ||
Crucial role of insulin receptor substrate-2 in compensatory beta-cell hyperplasia in response to high fat diet-induced insulin resistance | Q46332802 | ||
Integration of DIGE and bioinformatics analyses reveals a role of the antiobesity agent tungstate in redox and energy homeostasis pathways in brown adipose tissue | Q46912061 | ||
Tungstate decreases weight gain and adiposity in obese rats through increased thermogenesis and lipid oxidation | Q47375837 | ||
Sodium tungstate regulates food intake and body weight through activation of the hypothalamic leptin pathway. | Q47397864 | ||
Contrasting effects of IRS-1 versus IRS-2 gene disruption on carbohydrate and lipid metabolism in vivo. | Q48702756 | ||
Irs-2 coordinates Igf-1 receptor-mediated beta-cell development and peripheral insulin signalling. | Q52174749 | ||
Insulin-like Growth Factor 1 Inhibits Apoptosis Using the Phosphatidylinositol 3′-Kinase and Mitogen-activated Protein Kinase Pathways | Q58197201 | ||
IRS-2 pathways integrate female reproduction and energy homeostasis | Q59088199 | ||
P433 | issue | 1 | |
P304 | page(s) | E36-47 | |
P577 | publication date | 2013-11-19 | |
P1433 | published in | American Journal of Physiology - Endocrinology and Metabolism | Q15765671 |
P1476 | title | Tungstate promotes β-cell survival in Irs2-/- mice | |
P478 | volume | 306 |
Q28385348 | An update to the toxicological profile for water-soluble and sparingly soluble tungsten substances |
Q91790389 | Effects of D-Chiro-Inositol on Glucose Metabolism in db/db Mice and the Associated Underlying Mechanisms |
Q35618949 | Preclinical and Clinical Studies for Sodium Tungstate: Application in Humans. |
Q38224544 | Targeting type 2 diabetes: lessons from a knockout model of insulin receptor substrate 2. |
Q55531998 | The Antidiabetic Agent Sodium Tungstate Induces Abnormal Glycogen Accumulation in Renal Proximal Tubules from Diabetic IRS2-Knockout Mice. |
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