| scholarly article | Q13442814 |
| P356 | DOI | 10.1016/S0092-8674(85)80053-2 |
| P698 | PubMed publication ID | 3924409 |
| P2093 | author name string | M Steinmetz | |
| R Palacios | |||
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| Plasmid-Determined Resistance to Antimicrobial Agents | Q39776156 | ||
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| Pre-B cells; normal and abnormal development | Q40263609 | ||
| Formation of B lymphocytes in fetal and adult life. | Q40321123 | ||
| Two rearranged immunoglobulin kappa light chain genes in one mouse myeloma | Q40481136 | ||
| T-helper function of parent leads to F1 chimeras. Presence of a separate T-cell subgroup able to stimulate allogeneic B cells but not syngeneic B cells | Q40701106 | ||
| B220: a B cell-specific member of th T200 glycoprotein family | Q42800334 | ||
| A plaque assay for all cells secreting Ig of a given type or class | Q44062553 | ||
| P433 | issue | 3 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | lymphocyte | Q715347 |
| P304 | page(s) | 727-734 | |
| P577 | publication date | 1985-07-01 | |
| P1433 | published in | Cell | Q655814 |
| P1476 | title | Il-3-dependent mouse clones that express B-220 surface antigen, contain Ig genes in germ-line configuration, and generate B lymphocytes in vivo. | |
| P478 | volume | 41 |
| Q35201827 | A GATA-2/estrogen receptor chimera functions as a ligand-dependent negative regulator of self-renewal |
| Q34488193 | A core region of the mafK gene IN promoter directs neurone-specific transcription in vivo |
| Q33774162 | A critical role for cyclin C in promotion of the hematopoietic cell cycle by cooperation with c-Myc |
| Q24563301 | A direct binding site for Grb2 contributes to transformation and leukemogenesis by the Tel-Abl (ETV6-Abl) tyrosine kinase |
| Q36649362 | A dominant negative erythropoietin (EPO) receptor inhibits EPO-dependent growth and blocks F-gp55-dependent transformation |
| Q28472406 | A dual-color fluorescence-based platform to identify selective inhibitors of Akt signaling |
| Q24323368 | A functional interleukin 12 receptor complex is composed of two beta-type cytokine receptor subunits |
| Q33890169 | A link between cell cycle and cell death: Bax and Bcl-2 modulate Cdk2 activation during thymocyte apoptosis. |
| Q38298152 | A novel enhancer, the pro-B enhancer, regulates Id1 gene expression in progenitor B cells |
| Q39721838 | A novel method to isolate cells with conditional gene expression using fluorescence activated cell sorting |
| Q36077799 | A proliferation switch for genetically modified cells |
| Q41063635 | A role for JNK/SAPK in proliferation, but not apoptosis, of IL-3-dependent cells |
| Q33890119 | A single amino acid substitution in a WW-like domain of diverse members of the PDGF receptor subfamily of tyrosine kinases causes constitutive receptor activation |
| Q24648750 | A single tyrosine of the interleukin-9 (IL-9) receptor is required for STAT activation, antiapoptotic activity, and growth regulation by IL-9 |
| Q24291506 | A soluble class II cytokine receptor, IL-22RA2, is a naturally occurring IL-22 antagonist |
| Q40794199 | A temperature sensitive p210 BCR-ABL mutant defines the primary consequences of BCR-ABL tyrosine kinase expression in growth factor dependent cells. |
| Q40542763 | A truncated isoform of c-Mpl with an essential C-terminal peptide targets the full-length receptor for degradation |
| Q40595051 | AML1/RUNX1 increases during G1 to S cell cycle progression independent of cytokine-dependent phosphorylation and induces cyclin D3 gene expression |
| Q36900679 | Abelson virus abrogation of interleukin-3 dependence in a lymphoid cell line |
| Q53525558 | Abnormalities in DNA rearrangements of immunoglobulin gene loci in precursor B cells derived from X-linked agammaglobulinemia patient and a severe combined immunodeficiency patient. |
| Q40751543 | Abnormality of c-kit oncoprotein in certain patients with chronic myelogenous leukemia--potential clinical significance |
| Q33254113 | Abrogation of viral interleukin-6 (vIL-6)-induced signaling by intracellular retention and neutralization of vIL-6 with an anti-vIL-6 single-chain antibody selected by phage display |
| Q36505270 | Absence of cytokine receptor-dependent specificity in red blood cell differentiation in vivo |
| Q71173528 | Acceleration of IgE responses by treatment with recombinant interleukin-3 prior to infection with Trichinella spiralis in mice |
| Q38614149 | Activation and functional analysis of Janus kinase 2 in BA/F3 cells using the coumermycin/gyrase B system |
| Q28609160 | Activation of ErbB4 by the bifunctional epidermal growth factor family hormone epiregulin is regulated by ErbB2 |
| Q33883366 | Activation of JAK2-V617F by components of heterodimeric cytokine receptors |
| Q40744434 | Activation of STAT5 triggers proliferation and contributes to anti-apoptotic signalling mediated by the oncogenic Xmrk kinase |
| Q39415399 | Activation of target signal transducers utilizing chimeric receptors with signaling-molecule binding motifs |
| Q33781714 | Activation of the Ras/mitogen-activated protein kinase pathway by kinase-defective epidermal growth factor receptors results in cell survival but not proliferation |
| Q40399553 | Activation of the immunoglobulin kappa 3' enhancer in pre-B cells correlates with the suppression of a nuclear factor binding to a sequence flanking the active core |
| Q40787375 | Activation of the transcription factor NF-kappaB by the erythropoietin receptor: structural requirements and biological significance |
| Q40613603 | Active and inactive orientations of the transmembrane and cytosolic domains of the erythropoietin receptor dimer |
| Q40380373 | Acute activation of Erk1/Erk2 and protein kinase B/akt proceed by independent pathways in multiple cell types. |
| Q40104197 | Akt shows variable sensitivity to an Hsp90 inhibitor depending on cell context. |
| Q42552328 | An Inducible Retroviral Expression System for Tandem Affinity Purification Mass-Spectrometry-Based Proteomics Identifies Mixed Lineage Kinase Domain-like Protein (MLKL) as an Heat Shock Protein 90 (HSP90) Client |
| Q38354181 | An activating mutation in the ATP binding site of the ABL kinase domain. |
| Q41875441 | An activating mutation in the murine erythropoietin receptor induces erythroleukemia in mice: A cytokine receptor superfamily oncogene |
| Q40357987 | An amphipathic motif at the transmembrane-cytoplasmic junction prevents autonomous activation of the thrombopoietin receptor. |
| Q38756560 | Analysis of acquired mutations in transgenes arising in Ba/F3 transformation assays: findings and recommendations. |
| Q73089654 | Analysis of cis-acting sequences and trans-acting factors regulating the interleukin-3 response element of the DUB-1 gene |
| Q40896666 | Analysis of mechanisms involved in the prevention of gamma irradiation-induced apoptosis by hGM-CSF. |
| Q50336633 | Anosmin-1 modulates fibroblast growth factor receptor 1 signaling in human gonadotropin-releasing hormone olfactory neuroblasts through a heparan sulfate-dependent mechanism. |
| Q28345081 | Apoptosis of haematopoietic cells upon thymidylate synthase inhibition is independent of p53 accumulation and CD95-CD95 ligand interaction |
| Q40464878 | Apoptosis of hematopoietic cells induced by growth factor withdrawal is associated with caspase-9 mediated cleavage of Raf-1. |
| Q41187642 | Aqueous stability of recombinant human thrombopoietin as a function of processing schemes |
| Q35146759 | Assembling ligands in situ using bioorthogonal boronate ester synthesis |
| Q40872061 | Association of p56lck with IL-2 receptor beta chain is critical for the IL-2-induced activation of p56lck |
| Q50134139 | B cell lymphoma 2 (Bcl-2) residues essential for Bcl-2's apoptosis-inducing interaction with Nur77/Nor-1 orphan steroid receptors. |
| Q69736123 | B cell precursors are present in the thymus during early development |
| Q37376649 | B lymphocytes from patients with chronic lymphocytic leukemia contain signal transducer and activator of transcription (STAT) 1 and STAT3 constitutively phosphorylated on serine residues. |
| Q40809849 | BCR-ABL and interleukin 3 promote haematopoietic cell proliferation and survival through modulation of cyclin D2 and p27Kip1 expression. |
| Q42335074 | Ba/F3 transformation assays |
| Q24647985 | Bach proteins belong to a novel family of BTB-basic leucine zipper transcription factors that interact with MafK and regulate transcription through the NF-E2 site |
| Q40549758 | Bacteria displaying interleukin-4 mutants stimulate mammalian cells and reflect the biological activities of variant soluble cytokines |
| Q37357899 | Bcr/Abl expression stimulates integrin function in hematopoietic cell lines |
| Q41002214 | Biochemical characterization of mutant EGF receptors expressed in the hemopoietic cell line BaF/3. |
| Q24530573 | Biological effects of c-Mer receptor tyrosine kinase in hematopoietic cells depend on the Grb2 binding site in the receptor and activation of NF-kappaB. |
| Q35742172 | Biologically active LIL proteins built with minimal chemical diversity |
| Q70025824 | Bone marrow pro-T and pro-B lymphocyte clones express functional receptors for interleukin (IL) 3 and IL 4/BSF-1 and nonfunctional receptors for IL 2 |
| Q40891304 | Bovine papillomavirus E5 protein induces the formation of signal transduction complexes containing dimeric activated platelet-derived growth factor beta receptor and associated signaling proteins |
| Q39744509 | Bypassing antibiotic selection: positive screening of genetically modified cells with an antigen-dependent proliferation switch |
| Q40804318 | C/EBPalpha and G-CSF receptor signals cooperate to induce the myeloperoxidase and neutrophil elastase genes |
| Q34924432 | C/EBPα and C/EBPα oncoproteins regulate nfkb1 and displace histone deacetylases from NF-κB p50 homodimers to induce NF-κB target genes |
| Q68809218 | CC11: a monoclonal antibody specific for interleukin 3-sensitive mouse cells defines two major populations of B cell precursors in the bone marrow |
| Q33775064 | CCAAT/enhancer binding protein alpha is a regulatory switch sufficient for induction of granulocytic development from bipotential myeloid progenitors |
| Q30010282 | CIN85 interacting proteins in B cells-specific role for SHIP-1. |
| Q39075134 | CSF1R mutations in hereditary diffuse leukoencephalopathy with spheroids are loss of function |
| Q40365089 | Cancer development induced by graded expression of Snail in mice. |
| Q37010433 | Cancer induction by restriction of oncogene expression to the stem cell compartment |
| Q40865547 | Cell-growth control by monomeric antigen: the cell surface expression of lysozyme-specific Ig V-domains fused to truncated Epo receptor |
| Q28144144 | Characterization of FIM-FGFR1, the fusion product of the myeloproliferative disorder-associated t(8;13) translocation |
| Q36870553 | Characterization of Potential Antagonists of Human Interleukin 5 Demonstrates Their Cross‐Reactivity with Receptors for Interleukin 3 and Granulocyte‐Macrophage Colony‐Stimulating Factor |
| Q40934024 | Characterization of a bioassay for detection of recombinant and native ovine interleukin-5. |
| Q38293999 | Characterization of critical residues in the cytoplasmic domain of the human interleukin-5 receptor alpha chain required for growth signal transduction |
| Q24302347 | Characterization of p87C3G, a novel, truncated C3G isoform that is overexpressed in chronic myeloid leukemia and interacts with Bcr-Abl |
| Q41107677 | Characterization of the receptor binding determinants of granulocyte colony stimulating factor |
| Q33908547 | Clonal competition in BcrAbl-driven leukemia: how transplantations can accelerate clonal conversion. |
| Q24557510 | Cloning and expression of a widely expressed receptor tyrosine phosphatase |
| Q36406762 | Cloning and expression of porcine Colony Stimulating Factor-1 (CSF-1) and Colony Stimulating Factor-1 Receptor (CSF-1R) and analysis of the species specificity of stimulation by CSF-1 and Interleukin 34. |
| Q24336395 | Cloning of a murine IL-11 receptor alpha-chain; requirement for gp130 for high affinity binding and signal transduction |
| Q36356099 | Cloning of phenotypically different human lymphocytes originating from a single stem cell |
| Q37112849 | Comparative analysis of oncogenic properties and nuclear factor-kappaB activity of latent membrane protein 1 natural variants from Hodgkin's lymphoma's Reed-Sternberg cells and normal B-lymphocytes |
| Q41575461 | Comparison of the levels of inositol metabolites in transformed haemopoietic cells and their normal counterparts. |
| Q41116748 | Conformational changes required in the human growth hormone receptor for growth hormone signaling. |
| Q36571164 | Control of thrombopoietin-induced megakaryocytic differentiation by the mitogen-activated protein kinase pathway |
| Q40975219 | Cooperation of p38 and extracellular signal-regulated kinase mitogen-activated protein kinase pathways during granulocyte colony-stimulating factor-induced hemopoietic cell proliferation |
| Q74604694 | Cooperative and redundant effects of STAT5 and Ras signaling in BCR/ABL transformed hematopoietic cells |
| Q28274169 | Cotranscription and intergenic splicing of human galactose-1-phosphate uridylyltransferase and interleukin-11 receptor alpha-chain genes generate a fusion mRNA in normal cells. Implication for the production of multidomain proteins during evolution |
| Q28608970 | Critical cytoplasmic domains of the common beta subunit of the human GM-CSF, IL-3 and IL-5 receptors for growth signal transduction and tyrosine phosphorylation |
| Q28508035 | Critical role of the TIE2 endothelial cell receptor in the development of definitive hematopoiesis |
| Q90658988 | Cryo-EM structure of a dimeric B-Raf:14-3-3 complex reveals asymmetry in the active sites of B-Raf kinases |
| Q39988132 | Cyclin D1 mediates resistance to apoptosis through upregulation of molecular chaperones and consequent redistribution of cell death regulators |
| Q33959940 | Cytokine receptor common beta chain as a potential activator of cytokine withdrawal-induced apoptosis |
| Q40763830 | Cytokine receptor common beta subunit-mediated STAT5 activation confers NF-kappa B activation in murine proB cell line Ba/F3 cells |
| Q37059944 | Cytokine-induced nuclear translocation of signaling proteins and their analysis using the inducible translocation trap system. |
| Q28592240 | DUB-1, a deubiquitinating enzyme with growth-suppressing activity |
| Q38900285 | Deacetylase inhibitors repress STAT5-mediated transcription by interfering with bromodomain and extra-terminal (BET) protein function |
| Q40710486 | Definition of an inhibitory juxtamembrane WW-like domain in the platelet-derived growth factor beta receptor |
| Q55007974 | Deletion of Src homology 3 domain results in constitutive activation of Tec protein-tyrosine kinase. |
| Q61048563 | Development of lymphocytes in interleukin 7-transgenic mice |
| Q41612756 | Developmentally regulated cell surface expression and function of c-kit receptor during lymphocyte ontogeny in the embryo and adult mice |
| Q41686468 | Different stromal cell lines support lineage-selective differentiation of the multipotential bone marrow stem cell clone LyD9. |
| Q40464506 | Differential STAT5 signaling by ligand-dependent and constitutively active cytokine receptors. |
| Q28303959 | Differential associations between the cytoplasmic regions of the interleukin-12 receptor subunits beta1 and beta2 and JAK kinases |
| Q40241741 | Differential regulation of early response genes and cell proliferation through the human granulocyte macrophage colony-stimulating factor receptor: selective activation of the c-fos promoter by genistein |
| Q39574462 | Differentiation of a precursor cell with the germline context immunoglobulin gene into immunoglobulin-producing cells in vitro |
| Q33582641 | Differentiation of an interleukin 3-dependent precursor B-cell clone into immunoglobulin-producing cells in vitro |
| Q34969897 | Direct activation of STAT5 by ETV6-LYN fusion protein promotes induction of myeloproliferative neoplasm with myelofibrosis. |
| Q28743749 | Direct identification of insulator components by insertional chromatin immunoprecipitation |
| Q41275571 | Discrimination of apoptotic thymocytes by forward light scatter |
| Q36756480 | Distinct cytoplasmic regions of the human granulocyte colony-stimulating factor receptor involved in induction of proliferation and maturation |
| Q59097131 | Distinct factors bind to apparently homolgous sequences in the immunoglobulin heavy-chain enhancer |
| Q28143141 | Distinct roles for STAT1, STAT3, and STAT5 in differentiation gene induction and apoptosis inhibition by interleukin-9 |
| Q38768199 | Diverse, Biologically Relevant, and Targetable Gene Rearrangements in Triple-Negative Breast Cancer and Other Malignancies |
| Q41101434 | EBF and E47 collaborate to induce expression of the endogenous immunoglobulin surrogate light chain genes |
| Q46640466 | Early arrest of B cell development in nude, X-linked immune-deficient mice |
| Q40811164 | Ectopic expression of cyclin D1 impairs the proliferation and enhances the apoptosis of a murine lymphoid cell line. |
| Q34556842 | Engineering and Functional Characterization of Fusion Genes Identifies Novel Oncogenic Drivers of Cancer. |
| Q33937392 | Enrichment and characterization of uncommitted B-cell precursors from fetal liver at day 12 of gestation |
| Q27865182 | Epidermal growth factor receptor activation in glioblastoma through novel missense mutations in the extracellular domain |
| Q52197267 | Epo-induced hemoglobinization of SKT6 cells is mediated by minimal cytoplasmic domains of the Epo or prolactin receptors without modulation of GATA-1 or EKLF. |
| Q28251507 | Erythropoietin induces the tyrosine phosphorylation of insulin receptor substrate-2. An alternate pathway for erythropoietin-induced phosphatidylinositol 3-kinase activation |
| Q36702398 | Erythropoietin receptor signals both proliferation and erythroid-specific differentiation |
| Q33920201 | Establishment of an interleukin-5-dependent subclone from an interleukin-3-dependent murine hemopoietic progenitor cell line, LyD9, and its malignant transformation by autocrine secretion of interleukin-5 |
| Q34024987 | Evaluating erythropoietin-associated tumor progression using archival tissues from a phase III clinical trial |
| Q41450864 | Evidence for a critical role for the cytoplasmic region of the interleukin 2 (IL-2) receptor gamma chain in IL-2, IL-4, and IL-7 signalling |
| Q41741318 | Evidence that the level of the p55 component of the interleukin (IL) 2 receptor can control IL 2 responsiveness in a murine IL 3-dependent cell |
| Q60923199 | Ex Vivo Transposon-Mediated Genetic Screens for Cancer Gene Discovery |
| Q33852935 | Experimental approaches to hypothetical hormones: detection of a candidate ligand of the neu protooncogene |
| Q38550035 | Expressed luciferase viability assay (ELVA) for the measurement of cell growth and viability |
| Q62819858 | Expression of BCR – ABL in M1 myeloid leukemia cells induces differentiation without arresting proliferation |
| Q33889628 | Expression of the LIM-homeobox gene LH2 generates immortalized steel factor-dependent multipotent hematopoietic precursors. |
| Q38332198 | Expression of the RAG-2 gene in murine central nervous system tumor cell lines |
| Q41526350 | Expression, purification and crystallization of fully active, glycosylated human interleukin-5. |
| Q42174977 | Extracellular domain N-glycosylation controls human thrombopoietin receptor cell surface levels |
| Q36811855 | Fetal liver pro-B and pre-B lymphocyte clones: expression of lymphoid-specific genes, surface markers, growth requirements, colonization of the bone marrow, and generation of B lymphocytes in vivo and in vitro |
| Q28609648 | Fibroblast growth factor receptors have different signaling and mitogenic potentials |
| Q34698039 | Forced dimerization of gp130 leads to constitutive STAT3 activation, cytokine-independent growth, and blockade of differentiation of embryonic stem cells |
| Q41097922 | Formation of an active tissue-specific chromatin domain initiated by epigenetic marking at the embryonic stem cell stage. |
| Q33412741 | Functional characterization of c-Mpl ectodomain mutations that underlie congenital amegakaryocytic thrombocytopenia |
| Q40276991 | Functional expression of a biologically active fragment of soluble gp130 as an ELP-fusion protein in transgenic plants: purification via inverse transition cycling |
| Q41149871 | Functional replacement of cytokine receptor extracellular domains by leucine zippers |
| Q28743977 | Functional studies on the IBD susceptibility gene IL23R implicate reduced receptor function in the protective genetic variant R381Q |
| Q39574814 | GATA-1 dominantly activates a program of erythroid gene expression in factor-dependent myeloid FDCW2 cells |
| Q39694616 | Gatekeeper mutations mediate resistance to BRAF-targeted therapies. |
| Q41976222 | Generation of continuous large granular lymphocyte lines by interleukin 2 from the spleen cells of mice infected with Moloney leukemia virus. Involvement of interleukin 3. |
| Q31029794 | Genetic complementation of cytokine signaling identifies central role of kinases in hematopoietic cell proliferation |
| Q28283759 | Grb10/GrbIR as an in vivo substrate of Tec tyrosine kinase |
| Q37371968 | Growth as a solid tumor or reduced glucose concentrations in culture reversibly induce CD44-mediated hyaluronan recognition by Chinese hamster ovary cells |
| Q41365779 | Growth factor modulation of p53-mediated growth arrest versus apoptosis |
| Q41294941 | Growth signal transduction by the human interleukin-2 receptor requires cytoplasmic tyrosines of the beta chain and non-tyrosine residues of the gamma c chain. |
| Q47720679 | Haemopoietic transformation by the TEL/ABL oncogene. |
| Q36774107 | Helix-loo-helix proteins in the regulation of immunoglobulin gene transcription |
| Q40724152 | Heparan sulfate-growth factor interactions |
| Q38331586 | Heparin is required for cell-free binding of basic fibroblast growth factor to a soluble receptor and for mitogenesis in whole cells |
| Q49252646 | Highly multiplexed single-cell quantitative PCR. |
| Q41166284 | Homodimerization of interleukin-4 receptor alpha chain can induce intracellular signaling |
| Q40687431 | Human GM-CSF induces HIV-1 LTR by multiple signalling pathways |
| Q41759266 | Human interleukin 2 (IL 2) receptor beta chain allows transduction of IL 2-induced proliferation signal(s) in a murine cell line |
| Q41562450 | Human interleukin-4 receptor signaling requires sequences contained within two cytoplasmic regions |
| Q37162871 | ICSBP-mediated immune protection against BCR-ABL-induced leukemia requires the CCL6 and CCL9 chemokines |
| Q22254387 | Identification and characterization of a novel cell cycle-regulated internal ribosome entry site |
| Q36351952 | Identification and characterization of pro-T lymphocytes and lineage-uncommitted lymphocyte precursors from mice with three novel surface markers |
| Q37632995 | Identification of JAK protein tyrosine kinases as signaling molecules for prolactin. Functional analysis of prolactin receptor and prolactin-erythropoietin receptor chimera expressed in lymphoid cells. |
| Q36377998 | Identification of Variant-Specific Functions of PIK3CA by Rapid Phenotyping of Rare Mutations |
| Q35025251 | Identification of a STAT5 target gene, Dpf3, provides novel insights in chronic lymphocytic leukemia |
| Q39016705 | Identification of a new Mpl-interacting protein, Atp5d |
| Q40198860 | Identification of a novel EGF-sensitive cell cycle checkpoint |
| Q46458028 | Identification of a variable region within the cytoplasmic tail of the IL-2 receptor beta chain that is required for growth signal transduction |
| Q35895171 | Identification of amino acids in the transmembrane and juxtamembrane domains of the platelet-derived growth factor receptor required for productive interaction with the bovine papillomavirus E5 protein |
| Q35392175 | Identification of non-coding RNAs associated with telomeres using a combination of enChIP and RNA sequencing |
| Q34321183 | Identification of nuclear protein targets for six leukemogenic tyrosine kinases governed by post-translational regulation |
| Q39575087 | Identification of the cytoplasmic regions of fibroblast growth factor (FGF) receptor 1 which play important roles in induction of neurite outgrowth in PC12 cells by FGF-1. |
| Q27851410 | Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer |
| Q41525082 | Identification of three adjacent amino acids of interleukin-2 receptor beta chain which control the affinity and the specificity of the interaction with interleukin-2 |
| Q34384711 | Imaging the intracellular distribution of tyrosine kinase inhibitors in living cells with quantitative hyperspectral stimulated Raman scattering |
| Q70378954 | Immunoglobulin gene expression is a normal differentiation event in embryonic thymocytes |
| Q33841120 | In vitro effects of recombinant interleukin 7 on growth and differentiation of bone marrow pro-B- and pro-T-lymphocyte clones and fetal thymocyte clones. |
| Q34497738 | In vitro validation of bioluminescent monitoring of disease progression and therapeutic response in leukaemia model animals |
| Q28242665 | In vivo repression by a site-specific DNA-binding protein designed against an oncogenic sequence |
| Q36967528 | Inhibition of fibroblast growth factor receptor 3-dependent lung adenocarcinoma with a human monoclonal antibody. |
| Q37033273 | Insertional gene activation by lentiviral and gammaretroviral vectors. |
| Q36679345 | Interaction between NF-kappa B- and serum response factor-binding elements activates an interleukin-2 receptor alpha-chain enhancer specifically in T lymphocytes |
| Q40949181 | Interaction of granulocyte colony-stimulating factor (G-CSF) with its receptor. Evidence that Glu19 of G-CSF interacts with Arg288 of the receptor |
| Q40729143 | Interferon-alpha inhibits cell cycle progression by Ba/F3 cells through the antagonisation of interleukin-3 effects on key regulators of G(1)/S transition |
| Q38347603 | Interferon-alpha inhibits interleukin-3-induced proliferation of Ba/F3 cells in a protein kinase R-dependent manner |
| Q40916049 | Interferon-alpha inhibits proliferation of Ba/F3 cells by interfering with interleukin-3 action |
| Q36362418 | Interleukin 2 activates extracellular signal-regulated protein kinase 2. |
| Q41651678 | Interleukin 2 and Tumor Necrosis Factor α are Complementary for Proliferation of the Hematopoietic Stem Cell Line LyD9 |
| Q24290522 | Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function |
| Q36356453 | Interleukin 3 (IL-3) induces transcription from nonrearranged T cell receptor gamma loci in IL-3-dependent cell lines |
| Q36231901 | Interleukin 3 protects murine bone marrow cells from apoptosis induced by DNA damaging agents |
| Q28265772 | Interleukin 31, a cytokine produced by activated T cells, induces dermatitis in mice |
| Q41155420 | Interleukin-3 (IL-3) inhibits erythropoietin-induced differentiation in Ba/F3 cells via the IL-3 receptor alpha subunit |
| Q41486062 | Interleukin-3 and Bcl-2 cooperatively inhibit etoposide-induced apoptosis in a murine pre-B cell line. |
| Q39657462 | Interleukin-7-induced Stat-5 acts in synergy with Flt-3 signaling to stimulate expansion of hematopoietic progenitor cells. |
| Q39606583 | Interleukins: from purified proteins to chains, circles, cascades and other complexities |
| Q30480832 | Internalization, intracellular trafficking, and biodistribution of monoclonal antibody 806: a novel anti-epidermal growth factor receptor antibody |
| Q37237331 | Investigating human leukemogenesis: from cell lines to in vivo models of human leukemia |
| Q74200513 | Involvement of p53 and interleukin 3 in the up-regulation of CD95 (APO-1/Fas) by X-ray irradiation |
| Q37483255 | Involvement of ras p21 protein in signal-transduction pathways from interleukin 2, interleukin 3, and granulocyte/macrophage colony-stimulating factor, but not from interleukin 4 |
| Q41390488 | Involvement of the interleukin-2 receptor gamma subunit in interleukin-4-dependent activation of mouse hematopoietic cells and splenic B cells |
| Q41455300 | Isolation of tyrosine kinase related genes expressed in the early hematopoietic system |
| Q40079753 | JAK kinases overexpression promotes in vitro cell transformation |
| Q40022414 | JAK2 is required for induction of the murine DUB-1 gene |
| Q34087180 | JAK2, complemented by a second signal from c-kit or flt-3, triggers extensive self-renewal of primary multipotential hemopoietic cells |
| Q40944633 | JNK activation is not required for Fas-mediated apoptosis |
| Q40420997 | Janus kinases affect thrombopoietin receptor cell surface localization and stability |
| Q36837473 | Leptin can induce proliferation, differentiation, and functional activation of hemopoietic cells. |
| Q24310069 | Ligand for FLT3/FLK2 receptor tyrosine kinase regulates growth of haematopoietic stem cells and is encoded by variant RNAs |
| Q36550896 | Ligand-independent activation of the platelet-derived growth factor beta receptor: requirements for bovine papillomavirus E5-induced mitogenic signaling |
| Q31473336 | Ligand-independent dimerization and activation of the oncogenic Xmrk receptor by two mutations in the extracellular domain |
| Q42044657 | Ligand-independent homomeric and heteromeric complexes between interleukin-2 or -9 receptor subunits and the gamma chain. |
| Q42589992 | Lipopolysaccharide interaction with cell surface Toll-like receptor 4-MD-2: higher affinity than that with MD-2 or CD14. |
| Q39705691 | Long-term culture systems for analysis of early B lymphocyte development |
| Q35921230 | Long-term proliferating early pre B cell lines and clones with the potential to develop to surface Ig-positive, mitogen reactive B cells in vitro and in vivo. |
| Q33929950 | Ly1+ PRO-B lymphocyte clones. Phenotype, growth requirements and differentiation in vitro and in vivo |
| Q41540937 | Lymphoid precursor cells adhere to two different sites on fibronectin |
| Q37348266 | M-CSF elevates c-Fos and phospho-C/EBPalpha(S21) via ERK whereas G-CSF stimulates SHP2 phosphorylation in marrow progenitors to contribute to myeloid lineage specification |
| Q34273369 | MAPK phosphatase DUSP16/MKP-7, a candidate tumor suppressor for chromosome region 12p12-13, reduces BCR-ABL-induced transformation |
| Q22009943 | MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4 |
| Q51083278 | MPT0B002, a novel microtubule inhibitor, downregulates T315I mutant Bcr-Abl and induces apoptosis of imatinib-resistant chronic myeloid leukemia cells. |
| Q37535249 | MUC1-C oncoprotein promotes FLT3 receptor activation in acute myeloid leukemia cells |
| Q33902807 | Mediation by the protein-tyrosine kinase Tec of signaling between the B cell antigen receptor and Dok-1. |
| Q37690147 | Meprin Metalloproteases Generate Biologically Active Soluble Interleukin-6 Receptor to Induce Trans-Signaling |
| Q90217105 | Metallopeptidase inhibitor 1 (TIMP-1) promotes receptor tyrosine kinase c-Kit signaling in colorectal cancer |
| Q36824500 | Mitogenic Signalling and Substrate Specificity of the Flk2/Flt3 Receptor Tyrosine Kinase in Fibroblasts and Interleukin 3-Dependent Hematopoietic Cells |
| Q35739439 | Modulation of cell death by Bcl-XL through caspase interaction |
| Q37564472 | Modulation of growth factor receptor function by isoform heterodimerization |
| Q40701066 | Molecular examination of the transmembrane requirements of the platelet-derived growth factor beta receptor for a productive interaction with the bovine papillomavirus E5 oncoprotein |
| Q28216722 | Molecular interactions of SHP1 and SHP2 in IL-3-signalling |
| Q26769659 | Molecular mechanisms that underpin EML4-ALK driven cancers and their response to targeted drugs |
| Q36353715 | Molecular, cellular, and functional properties of bone marrow T lymphocyte progenitor clones |
| Q24523671 | Mouse mammary tumor virus superantigen expression in B cells is regulated by a central enhancer within the pol gene |
| Q39675523 | Multimerization via its myosin domain facilitates nuclear localization and inhibition of core binding factor (CBF) activities by the CBFbeta-smooth muscle myosin heavy chain myeloid leukemia oncoprotein |
| Q41707575 | Multiple steps in the immortalization of cells of the B lineage |
| Q35000599 | Multiple transmembrane amino acid requirements suggest a highly specific interaction between the bovine papillomavirus E5 oncoprotein and the platelet-derived growth factor beta receptor |
| Q34054413 | Murine c-mpl: a member of the hematopoietic growth factor receptor superfamily that transduces a proliferative signal |
| Q37634171 | Mutagenesis of retroviral vectors transducing human beta-globin gene and beta-globin locus control region derivatives results in stable transmission of an active transcriptional structure |
| Q35094952 | Mutational analysis of a critical signaling domain of the human interleukin 4 receptor |
| Q30167708 | Mutational analysis of the regulatory function of the c-Abl Src homology 3 domain |
| Q37110277 | Myeloblastin is a granulocyte colony-stimulating factor-responsive gene conferring factor-independent growth to hematopoietic cells |
| Q40671312 | Nature and specificity of lymphokine independence induced by a selectable retroviral vector expressing v-src |
| Q28345510 | Negative cross-talk between interleukin-3 and interleukin-11 is mediated by suppressor of cytokine signalling-3 (SOCS-3) |
| Q34977719 | Negative regulation of early B lymphopoiesis by interleukin 3 and interleukin 1 alpha |
| Q81402332 | New mutations of MPL in primitive myelofibrosis: only the MPL W515 mutations promote a G1/S-phase transition |
| Q40662810 | New selective amplifier genes containing c-Mpl for hematopoietic cell expansion |
| Q35669297 | Nitric oxide and thiol redox regulation of Janus kinase activity |
| Q40678630 | Nonmyristoylated Abl proteins transform a factor-dependent hematopoietic cell line |
| Q36375198 | Novel point mutation in the extracellular domain of the granulocyte colony-stimulating factor (G-CSF) receptor in a case of severe congenital neutropenia hyporesponsive to G-CSF treatment. |
| Q41714456 | Novel primitive lymphoid tumours induced in transgenic mice by cooperation between myc and bcl-2. |
| Q24522838 | Nucleophosmin-anaplastic lymphoma kinase of large-cell anaplastic lymphoma is a constitutively active tyrosine kinase that utilizes phospholipase C-gamma to mediate its mitogenicity |
| Q54326636 | Omacetaxine mepesuccinate prevents cytokine-dependent resistance to nilotinib in vitro: potential role of the common β-subunit c of cytokine receptors. |
| Q35096609 | Oncogenic tyrosine kinases target Dok-1 for ubiquitin-mediated proteasomal degradation to promote cell transformation |
| Q36357100 | One synchronous wave of B cell development in mouse fetal liver changes at day 16 of gestation from dependence to independence of a stromal cell environment |
| Q58599659 | Overcoming EGFR-mediated osimertinib resistance through unique binding characteristics of second-generation EGFR inhibitors |
| Q41115446 | Overexpression of a heterologous thymidine kinase delays apoptosis induced by factor deprivation and inhibitors of deoxynucleotide metabolism |
| Q41145752 | P210 and P190(BCR/ABL) induce the tyrosine phosphorylation and DNA binding activity of multiple specific STAT family members |
| Q30904638 | Pearson correlation analysis of microarray data allows for the identification of genetic targets for early B-cell factor. |
| Q24564951 | Pivotal role for the NFIL3/E4BP4 transcription factor in interleukin 3-mediated survival of pro-B lymphocytes |
| Q37624867 | Point mutations within a dimer interface homology domain of c-Mpl induce constitutive receptor activity and tumorigenicity |
| Q39526448 | Prethymic and intrathymic mouse T-cell progenitors. Growth requirements and analysis of the expression of genes encoding TCR/T3 components and other T-cell-specific molecules |
| Q28285503 | Proteasomes regulate erythropoietin receptor and signal transducer and activator of transcription 5 (STAT5) activation. Possible involvement of the ubiquitinated Cis protein |
| Q37626301 | Protein abundance of AKT and ERK pathway components governs cell type-specific regulation of proliferation |
| Q40815901 | Proximal promoter of the murine syndecan-1 gene is not sufficient for the developmental pattern of syndecan expression in B lineage cells. |
| Q40539051 | Purification and characterization of a protein that binds to the recombination signal sequence of the immunoglobulin J kappa segment |
| Q36768954 | Quantification of apoptosis and necrosis by flow cytometry |
| Q33786920 | Rap1 is a potent activation signal for leukocyte function-associated antigen 1 distinct from protein kinase C and phosphatidylinositol-3-OH kinase |
| Q35605419 | Rearrangement of chicken immunoglobulin genes is not an ongoing process in the embryonic bursa of Fabricius |
| Q24320178 | Receptor specificity of the fibroblast growth factor family |
| Q41569898 | Reconstituted human granulocyte-macrophage colony-stimulating factor receptor transduces growth-promoting signals in mouse NIH 3T3 cells: comparison with signalling in BA/F3 pro-B cells |
| Q37529929 | Reconstitution of functional receptors for human granulocyte/macrophage colony-stimulating factor (GM-CSF): evidence that the protein encoded by the AIC2B cDNA is a subunit of the murine GM-CSF receptor |
| Q28508756 | Redundant promoter elements mediate IL-3-induced expression of a novel cytokine-inducible gene, cyclon |
| Q34319878 | Regulation of GATA-2 phosphorylation by mitogen-activated protein kinase and interleukin-3. |
| Q41224123 | Regulation of apoptosis in interleukin-3-dependent hemopoietic cells by interleukin-3 and calcium ionophores |
| Q41195279 | Regulation of the salvage pathway of deoxynucleotides synthesis in apoptosis induced by growth factor deprivation |
| Q40642489 | Repression of immunoglobulin enhancers by the helix-loop-helix protein Id: implications for B-lymphoid-cell development |
| Q41245740 | Retroviral vector design for gene therapy of cancer: specific inhibition and tagging of BCR-ABLp190 cells. |
| Q41175980 | Reversal of apoptosis by the leukaemia-associated E2A-HLF chimaeric transcription factor |
| Q40787492 | Role of Bax in apoptosis of IL-3-dependent cells. |
| Q40946907 | Role of STAT5 in interferon-alpha signal transduction in Ba/F3 cells |
| Q40453569 | SLUG in cancer development. |
| Q28252144 | SOCS-1/JAB/SSI-1 can bind to and suppress Tec protein-tyrosine kinase |
| Q24561861 | STK/RON receptor tyrosine kinase mediates both apoptotic and growth signals via the multifunctional docking site conserved among the HGF receptor family |
| Q34086066 | Sak serine-threonine kinase acts as an effector of Tec tyrosine kinase |
| Q41435366 | Serum alleviates the requirement of the granulocyte-macrophage colony-stimulating factor (GM-CSF)-induced Ras activation for proliferation of BaF3 cells. |
| Q28137857 | Shc associates with the IL-3 receptor β subunit, SHIP and Gab2 following IL-3 stimulation |
| Q35988744 | Signal transducer and activator of transcription STAT5 is recruited to c-Myc super-enhancer |
| Q30160307 | Signal transduction and cellular functions of the TEL/ARG oncoprotein |
| Q24564337 | Signal transduction by the high-affinity GM-CSF receptor: two distinct cytoplasmic regions of the common beta subunit responsible for different signaling |
| Q39705688 | Some facts about the progenitors of murine B lymphocytes |
| Q30480043 | Specific and covalent labeling of a membrane protein with organic fluorochromes and quantum dots |
| Q36559604 | Spi-1/PU.1 transgenic mice develop multistep erythroleukemias |
| Q64060862 | Splice donor site sgRNAs enhance CRISPR/Cas9-mediated knockout efficiency |
| Q74197200 | Src family kinases are required for prolactin induction of cell proliferation |
| Q79261538 | Stability and subcellular localization of API2-MALT1 chimeric protein involved in t(11;18) (q21;q21) MALT lymphoma |
| Q34175507 | Stable expression of immunoglobulin gene V(D)J recombinase activity by gene transfer into 3T3 fibroblasts |
| Q28202503 | Stemness, fusion and renewal of hematopoietic and embryonic stem cells |
| Q41460921 | Stimulation of megakaryocytopoiesis and thrombopoiesis by the c-Mpl ligand. |
| Q33898114 | Stimulation of mouse mammary tumor virus superantigen expression by an intragenic enhancer |
| Q33771375 | Stoichiometric structure-function analysis of the prolactin receptor signaling domain by receptor chimeras |
| Q36555271 | Structural and signaling requirements for BCR-ABL-mediated transformation and inhibition of apoptosis |
| Q40469656 | Structural requirements of the extracellular to transmembrane domain junction for erythropoietin receptor function. |
| Q40305409 | Subcellular localization of Bcr, Abl, and Bcr-Abl proteins in normal and leukemic cells and correlation of expression with myeloid differentiation |
| Q40230301 | Sustained leukaemic phenotype after inactivation of BCR-ABLp190 in mice. |
| Q40658192 | T-cell receptor and immunoglobulin genes are rearranged together in Abelson virus-transformed pre-B and pre-T cells |
| Q40879530 | TEL/PDGFbetaR fusion protein activates STAT1 and STAT5: a common mechanism for transformation by tyrosine kinase fusion proteins |
| Q34795604 | TGF-β-Neutralizing Antibody 1D11 Enhances Cytarabine-Induced Apoptosis in AML Cells in the Bone Marrow Microenvironment |
| Q28512952 | TROY, a newly identified member of the tumor necrosis factor receptor superfamily, exhibits a homology with Edar and is expressed in embryonic skin and hair follicles |
| Q36129030 | Targeting CDK1 promotes FLT3-activated acute myeloid leukemia differentiation through C/EBPα. |
| Q38302787 | The CD53 and CEACAM-1 genes are genetic targets for early B cell factor. |
| Q33688509 | The CRISPR/Cas9 system efficiently reverts the tumorigenic ability of BCR/ABL in vitro and in a xenograft model of chronic myeloid leukemia |
| Q36053065 | The Chemopreventive Phytochemical Moringin Isolated from Moringa oleifera Seeds Inhibits JAK/STAT Signaling |
| Q28214721 | The N-terminal domain of Janus kinase 2 is required for Golgi processing and cell surface expression of erythropoietin receptor |
| Q74066499 | The SH2 domain-containing protein tyrosine phosphatase SHP-1 is induced by granulocyte colony-stimulating factor (G-CSF) and modulates signaling from the G-CSF receptor |
| Q37143354 | The TEL-AML1 leukemia fusion gene dysregulates the TGF-beta pathway in early B lineage progenitor cells |
| Q40581361 | The TEL/ARG leukemia oncogene promotes viability and hyperresponsiveness to hematopoietic growth factors |
| Q41941514 | The beta c component of the granulocyte-macrophage colony-stimulating factor (GM-CSF)/interleukin 3 (IL-3)/IL-5 receptor interacts with a hybrid GM-CSF/erythropoietin receptor to influence proliferation and beta-globin mRNA expression |
| Q40988652 | The box-1 region of the leukemia inhibitory factor receptor alpha-chain cytoplasmic domain is sufficient for hemopoietic cell proliferation and differentiation. |
| Q41185142 | The box1 domain of the erythropoietin receptor specifies Janus kinase 2 activation and functions mitogenically within an interleukin 2 beta-receptor chimera |
| Q28287528 | The c-Mpl ligand (thrombopoietin) stimulates tyrosine phosphorylation of Jak2, Shc, and c-Mpl |
| Q41506573 | The c-kit receptor transduces the stem cell factor-triggered growth signal in murine interleukin-3-dependent cell line. |
| Q28609130 | The cellular response to neuregulins is governed by complex interactions of the erbB receptor family |
| Q24314280 | The cytoplasmic region of the erythropoietin receptor contains nonoverlapping positive and negative growth-regulatory domains |
| Q37577429 | The dual role of LSD1 and HDAC3 in STAT5-dependent transcription is determined by protein interactions, binding affinities, motifs and genomic positions. |
| Q33853516 | The envelope glycoprotein of friend spleen focus-forming virus covalently interacts with and constitutively activates a truncated form of the receptor tyrosine kinase Stk. |
| Q42816773 | The epigenetic influences of bone marrow and fetal liver stroma cells on the developmental potential of Ly-1+ pro-B lymphocyte clones |
| Q32138809 | The erythropoietin receptor cytosolic juxtamembrane domain contains an essential, precisely oriented, hydrophobic motif |
| Q39079942 | The impact of TEL-AML1 (ETV6-RUNX1) expression in precursor B cells and implications for leukaemia using three different genome-wide screening methods |
| Q33920771 | The ltk receptor tyrosine kinase is expressed in pre-B lymphocytes and cerebral neurons and uses a non-AUG translational initiator |
| Q41056192 | The macrosialin promoter directs high levels of transcriptional activity in macrophages dependent on combinatorial interactions between PU.1 and c-Jun |
| Q38327469 | The matrix metalloproteinase-9 regulates the insulin-like growth factor-triggered autocrine response in DU-145 carcinoma cells |
| Q34500384 | The molecular profiles of neural stem cell niche in the adult subventricular zone |
| Q33811050 | The mouse mammary tumor virus transcription enhancers for hematopoietic progenitor and mammary gland cells share functional elements |
| Q36562055 | The murine DUB-1 gene is specifically induced by the betac subunit of interleukin-3 receptor |
| Q28539573 | The natural chemopreventive agent sulforaphane inhibits STAT5 activity |
| Q41144407 | The response of IL-3 dependent B6SUtA bone marrow cells to both erythropoietin and chemical inducers of differentiation |
| Q36366835 | The role of gp130-mediated signals in osteoclast development: regulation of interleukin 11 production by osteoblasts and distribution of its receptor in bone marrow cultures. |
| Q38247896 | The role of interleukin-1 in the immunological response |
| Q40865232 | The role of p53 in death of IL-3-dependent cells in response to cytotoxic drugs |
| Q35111380 | The synthetic α-bromo-2',3,4,4'-tetramethoxychalcone (α-Br-TMC) inhibits the JAK/STAT signaling pathway |
| Q22254437 | The toll-like receptor protein RP105 regulates lipopolysaccharide signaling in B cells |
| Q40541045 | The tumor-specific de2-7 epidermal growth factor receptor (EGFR) promotes cells survival and heterodimerizes with the wild-type EGFR. |
| Q24316156 | Three distinct IL-2 signaling pathways mediated by bcl-2, c-myc, and lck cooperate in hematopoietic cell proliferation |
| Q41047876 | Thrombopoietin stimulates proliferation and megakaryocytic differentiation of mouse pro-B cell line BF-TE22 |
| Q68814158 | Thymus grafts induce B cell development in nude, X-linked immune deficient mice |
| Q37511971 | Trans-presentation of IL-6 by dendritic cells is required for the priming of pathogenic TH17 cells |
| Q36658475 | Transcriptional inhibition of the murine erythropoietin receptor gene by an upstream repetitive element |
| Q33682660 | Transformation of an interleukin 3-dependent hematopoietic cell line by the chronic myelogenous leukemia-specific P210bcr/abl protein |
| Q42378681 | Transforming Mutations of Jak3 (A573V and M511I) Show Differential Sensitivity to Selective Jak3 Inhibitors |
| Q34206916 | Tumorigenic activity of the BCR-ABL oncogenes is mediated by BCL2. |
| Q38614761 | Two distinct signaling pathways downstream of Janus kinase 2 play redundant roles for antiapoptotic activity of granulocyte-macrophage colony-stimulating factor |
| Q60064670 | Tyrosine kinase activation through the extracellular domains of cytokine receptors |
| Q35915787 | Tyrosine-599 of the c-Mpl receptor is required for Shc phosphorylation and the induction of cellular differentiation |
| Q36365946 | Tyrosyl phosphorylation and DNA binding activity of signal transducers and activators of transcription (STAT) proteins in hematopoietic cell lines transformed by Bcr/Abl |
| Q42360114 | Unwanted acquired mutations in Ba/F3 transformation assays |
| Q24307778 | Xk-related protein 8 and CED-8 promote phosphatidylserine exposure in apoptotic cells |
| Q69502133 | [Molecular biology and functions of interleukin 3, a growth factor for bone marrow cells] |
| Q41460906 | cMpl ligand is a humoral regulator of megakaryocytopoiesis |
| Q24314825 | p110δ, a novel phosphoinositide 3-kinase in leukocytes |
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