Frequency of KRAS, BRAF, and NRAS mutations in colorectal cancer.

scientific article

Frequency of KRAS, BRAF, and NRAS mutations in colorectal cancer. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/GCC.20854
P698PubMed publication ID21305640

P50authorWade S. SamowitzQ112111709
P2093author name stringChristine L Baker
Larissa V Furtado
Cecily P Vaughn
Scott D Zobell
P2860cites workKRAS mutation status is predictive of response to cetuximab therapy in colorectal cancer.Q27824867
KRAS mutations as an independent prognostic factor in patients with advanced colorectal cancer treated with cetuximab.Q27851422
Wild-type BRAF is required for response to panitumumab or cetuximab in metastatic colorectal cancerQ27851456
Effects of KRAS, BRAF, NRAS, and PIK3CA mutations on the efficacy of cetuximab plus chemotherapy in chemotherapy-refractory metastatic colorectal cancer: a retrospective consortium analysisQ27851573
Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancerQ28271324
Germline KRAS mutations cause Noonan syndromeQ28297024
Comparison of Sanger sequencing, pyrosequencing, and melting curve analysis for the detection of KRAS mutations: diagnostic and clinical implicationsQ33947050
Sensitive sequencing method for KRAS mutation detection by PyrosequencingQ35789986
Clinical relevance of KRAS mutation detection in metastatic colorectal cancer treated by Cetuximab plus chemotherapyQ36610301
RAS signaling in colorectal carcinomas through alteration of RAS, RAF, NF1, and/or RASSF1AQ36730389
High-throughput sequencing screen reveals novel, transforming RAS mutations in myeloid leukemia patientsQ37109358
KRAS codon 61, 146 and BRAF mutations predict resistance to cetuximab plus irinotecan in KRAS codon 12 and 13 wild-type metastatic colorectal cancer.Q37330719
Biomarkers predicting clinical outcome of epidermal growth factor receptor-targeted therapy in metastatic colorectal cancerQ37378581
Analysis of PTEN, BRAF, and EGFR status in determining benefit from cetuximab therapy in wild-type KRAS metastatic colon cancer.Q38934630
Biochemical characterization of a novel KRAS insertion mutation from a human leukemiaQ42806046
KRAS and BRAF mutations in advanced colorectal cancer are associated with poor prognosis but do not preclude benefit from oxaliplatin or irinotecan: results from the MRC FOCUS trialQ43250046
Impact of GSTT1, GSTM1, GSTP1 and NAT2 genotypes on KRAS2 and TP53 gene mutations in colorectal cancerQ44834239
KRAS wild-type state predicts survival and is associated to early radiological response in metastatic colorectal cancer treated with cetuximabQ46903224
Markers for EGFR pathway activation as predictor of outcome in metastatic colorectal cancer patients treated with or without cetuximab.Q54081321
PIK3CA Mutations Predict Local Recurrences in Rectal Cancer PatientsQ61481236
Alleles of APC modulate the frequency and classes of mutations that lead to colon polypsQ77647963
Association of K-ras mutational status and clinical outcomes in patients with metastatic colorectal cancer receiving panitumumab aloneQ81629286
High-resolution melting analysis for rapid detection of KRAS, BRAF, and PIK3CA gene mutations in colorectal cancerQ81643198
P433issue5
P921main subjectcolorectal cancerQ188874
P304page(s)307-312
P577publication date2011-02-08
P1433published inGenes, Chromosomes and CancerQ5532697
P1476titleFrequency of KRAS, BRAF, and NRAS mutations in colorectal cancer.
P478volume50

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