scholarly article | Q13442814 |
review article | Q7318358 |
P50 | author | Romain Joubert | Q61825596 |
Virginie Mariot | Q89839658 | ||
P2093 | author name string | Julie Dumonceaux | |
Anne-Charlotte Marsollier | |||
P2860 | cites work | DUX4, a candidate gene of facioscapulohumeral muscular dystrophy, encodes a transcriptional activator of PITX1 | Q24299685 |
A mechanism for the regulation of pre-mRNA 3' processing by human cleavage factor Im | Q24302567 | ||
The poly A polymerase Star-PAP controls 3'-end cleavage by promoting CPSF interaction and specificity toward the pre-mRNA | Q24307893 | ||
The novel poly(A) polymerase Star-PAP is a signal-regulated switch at the 3'-end of mRNAs | Q36765062 | ||
Degradation of mRNAs that lack a stop codon: a decade of nonstop progress | Q36802258 | ||
Mechanisms controlling production of membrane and secreted immunoglobulin during B cell development | Q36818995 | ||
Patterns of polyadenylation site selection in gene constructs containing multiple polyadenylation signals | Q36849107 | ||
Mutations in DNMT3B Modify Epigenetic Repression of the D4Z4 Repeat and the Penetrance of Facioscapulohumeral Dystrophy. | Q36891155 | ||
Alternative polyadenylation sites reveal distinct chromatin accessibility and histone modification in human cell lines | Q36985007 | ||
Protein factors in pre-mRNA 3'-end processing. | Q37044967 | ||
Human TREX component Thoc5 affects alternative polyadenylation site choice by recruiting mammalian cleavage factor I. | Q37080336 | ||
Progressive lengthening of 3' untranslated regions of mRNAs by alternative polyadenylation during mouse embryonic development. | Q37160188 | ||
Sequence variation between 462 human individuals fine-tunes functional sites of RNA processing | Q37248390 | ||
Morpholino-mediated Knockdown of DUX4 Toward Facioscapulohumeral Muscular Dystrophy Therapeutics | Q37256163 | ||
3' UTR-isoform choice has limited influence on the stability and translational efficiency of most mRNAs in mouse fibroblasts | Q37358020 | ||
Mammalian pre-mRNA 3' end processing factor CF I m 68 functions in mRNA export. | Q37475340 | ||
The myotonic dystrophies: molecular, clinical, and therapeutic challenges | Q38045121 | ||
PABPN1: molecular function and muscle disease | Q38100286 | ||
Molecular mechanisms in DM1 - a focus on foci. | Q38326275 | ||
Correlation between low FAT1 expression and early affected muscle in facioscapulohumeral muscular dystrophy | Q38505065 | ||
Evolution and Biological Roles of Alternative 3'UTRs | Q38644580 | ||
CstF-64 and 3'-UTR cis-element determine Star-PAP specificity for target mRNA selection by excluding PAPα. | Q38825492 | ||
Cleavage factor Im (CFIm) as a regulator of alternative polyadenylation | Q38928598 | ||
Purification and characterization of human cleavage factor Im involved in the 3' end processing of messenger RNA precursors | Q24309304 | ||
Structural basis of UGUA recognition by the Nudix protein CFI(m)25 and implications for a regulatory role in mRNA 3' processing | Q24313447 | ||
Human pre-mRNA cleavage factor Im is related to spliceosomal SR proteins and can be reconstituted in vitro from recombinant subunits | Q24313453 | ||
The 160-kD subunit of human cleavage-polyadenylation specificity factor coordinates pre-mRNA 3'-end formation | Q24314710 | ||
A PtdIns4,5P2-regulated nuclear poly(A) polymerase controls expression of select mRNAs | Q24315942 | ||
Human 5' --> 3' exonuclease Xrn2 promotes transcription termination at co-transcriptional cleavage sites | Q24317135 | ||
Participation of the nuclear cap binding complex in pre-mRNA 3' processing | Q24320261 | ||
Crystal structure of a human cleavage factor CFI(m)25/CFI(m)68/RNA complex provides an insight into poly(A) site recognition and RNA looping | Q24338977 | ||
Influenza A virus NS1 protein targets poly(A)-binding protein II of the cellular 3'-end processing machinery | Q24534097 | ||
Yhh1p/Cft1p directly links poly(A) site recognition and RNA polymerase II transcription termination | Q24534246 | ||
Human Fip1 is a subunit of CPSF that binds to U-rich RNA elements and stimulates poly(A) polymerase | Q24535920 | ||
Complex protein interactions within the human polyadenylation machinery identify a novel component | Q24554306 | ||
A CPSF-73 homologue is required for cell cycle progression but not cell growth and interacts with a protein having features of CPSF-100 | Q24557030 | ||
A large-scale analysis of mRNA polyadenylation of human and mouse genes | Q24557438 | ||
Cleavage and polyadenylation factor CPF specifically interacts with the pre-mRNA 3' processing signal AAUAAA | Q24564625 | ||
Assembly of a processive messenger RNA polyadenylation complex | Q24564750 | ||
Capping, splicing, and 3' processing are independently stimulated by RNA polymerase II: different functions for different segments of the CTD | Q24601077 | ||
U1 snRNP determines mRNA length and regulates isoform expression | Q24623251 | ||
Patterns of variant polyadenylation signal usage in human genes | Q24624061 | ||
RNA recognition by the human polyadenylation factor CstF | Q24646013 | ||
3' end mRNA processing: molecular mechanisms and implications for health and disease | Q24648650 | ||
Proliferating cells express mRNAs with shortened 3' untranslated regions and fewer microRNA target sites | Q24653978 | ||
Recognition of GU-rich polyadenylation regulatory elements by human CstF-64 protein | Q24671232 | ||
Poly(A)-binding proteins: multifunctional scaffolds for the post-transcriptional control of gene expression | Q24796373 | ||
Poly(A) polymerase (PAP) diversity in gene expression--star-PAP vs canonical PAP | Q26991894 | ||
Antisense oligonucleotides: treating neurodegeneration at the level of RNA | Q27007056 | ||
Deregulation of the protocadherin gene FAT1 alters muscle shapes: implications for the pathogenesis of facioscapulohumeral dystrophy | Q27322323 | ||
Crystal structure of the 25 kDa subunit of human cleavage factor Im | Q27650479 | ||
Hexameric architecture of CstF supported by CstF-50 homodimerization domain structure | Q27666576 | ||
A Mammalian Pre-mRNA 5′ End Capping Quality Control Mechanism and an Unexpected Link of Capping to Pre-mRNA Processing | Q27676995 | ||
Dysregulation of 4q35- and muscle-specific genes in fetuses with a short D4Z4 array linked to facio-scapulo-humeral dystrophy. | Q50738350 | ||
Antisense targeting of 3' end elements involved in DUX4 mRNA processing is an efficient therapeutic strategy for facioscapulohumeral dystrophy: a new gene-silencing approach. | Q50889865 | ||
Computer-based assessment for facioscapulohumeral dystrophy diagnosis. | Q50925534 | ||
A distal auxiliary element facilitates cleavage and polyadenylation of Dux4 mRNA in the pathogenic haplotype of FSHD. | Q50982781 | ||
An ordered pathway of assembly of components required for polyadenylation site recognition and processing. | Q51172966 | ||
Nuclear protein spreading: implication for pathophysiology of neuromuscular diseases. | Q54365453 | ||
Genome-wide analysis of pre-mRNA 3' end processing reveals a decisive role of human cleavage factor I in the regulation of 3' UTR length. | Q55056466 | ||
Primary structure and expression of bovine poly(A) polymerase | Q59097203 | ||
Position-dependent sequence elements downstream of AAUAAA are required for efficient rabbit beta-globin mRNA 3' end formation | Q68985721 | ||
Facioscapulohumeral muscular dystrophy | Q82663047 | ||
Differential DNA methylation of the D4Z4 repeat in patients with FSHD and asymptomatic carriers | Q87405047 | ||
Global 3' UTR shortening has a limited effect on protein abundance in proliferating T cells | Q38938771 | ||
Cleavage and polyadenylation: Ending the message expands gene regulation | Q39269835 | ||
The poly(A)-binding protein nuclear 1 suppresses alternative cleavage and polyadenylation sites. | Q39364902 | ||
Alternative polyadenylation mediates microRNA regulation of muscle stem cell function | Q39386660 | ||
De-regulation of the RBBP6 isoform 3/DWNN in human cancers | Q39433404 | ||
A functional human Poly(A) site requires only a potent DSE and an A-rich upstream sequence. | Q39722557 | ||
Stimulation of poly(A) polymerase through a direct interaction with the nuclear poly(A) binding protein allosterically regulated by RNA. | Q39790864 | ||
Two G-rich regulatory elements located adjacent to and 440 nucleotides downstream of the core poly(A) site of the intronless melanocortin receptor 1 gene are critical for efficient 3' end processing | Q40190265 | ||
In vivo aggregation properties of the nuclear poly(A)-binding protein PABPN1. | Q40438611 | ||
Genome modification leads to phenotype reversal in human myotonic dystrophy type 1 induced pluripotent stem cell-derived neural stem cells | Q40979450 | ||
Genome Therapy of Myotonic Dystrophy Type 1 iPS Cells for Development of Autologous Stem Cell Therapy | Q41092886 | ||
Ribosome-associated complex and Ssb are required for translational repression induced by polylysine segments within nascent chains | Q41170166 | ||
A core complex of CPSF73, CPSF100, and Symplekin may form two different cleavage factors for processing of poly(A) and histone mRNAs | Q41656652 | ||
Purification and characterization of a mammalian polyadenylate polymerase involved in the 3' end processing of messenger RNA precursors. | Q41767252 | ||
Molecular architecture of the human pre-mRNA 3' processing complex | Q42418612 | ||
Bioinformatic identification of candidate cis-regulatory elements involved in human mRNA polyadenylation | Q42868459 | ||
The beta-adrenergic system is involved in the regulation of the expression of avian uncoupling protein in the chicken. | Q43270931 | ||
Four factors are required for 3'-end cleavage of pre-mRNAs | Q43727383 | ||
mTOR as a Key Regulator in Maintaining Skeletal Muscle Mass | Q44682872 | ||
The prothrombin 3'end formation signal reveals a unique architecture that is sensitive to thrombophilic gain-of-function mutations | Q44826905 | ||
A novel poly(A)-binding protein acts as a specificity factor in the second phase of messenger RNA polyadenylation | Q45284501 | ||
Androgen receptors and muscle: a key mechanism underlying life history trade-offs. | Q46276412 | ||
Molecular Mechanisms for CFIm-Mediated Regulation of mRNA Alternative Polyadenylation | Q47256963 | ||
Structural insights into the assembly and polyA signal recognition mechanism of the human CPSF complex | Q47258918 | ||
The distinct transcriptomes of slow and fast adult muscles are delineated by noncoding RNAs. | Q47590628 | ||
Dynamic changes in copper homeostasis and post-transcriptional regulation of Atp7a during myogenic differentiation | Q47864682 | ||
mRNA 3'-UTR shortening is a molecular signature of mTORC1 activation | Q48173809 | ||
Cleavage factor Im is a key regulator of 3' UTR length | Q50320383 | ||
3' non-coding region sequences in eukaryotic messenger RNA | Q27860858 | ||
Evidence that polyadenylation factor CPSF-73 is the mRNA 3' processing endonuclease. | Q27932064 | ||
Independent functions of yeast Pcf11p in pre-mRNA 3' end processing and in transcription termination | Q27933119 | ||
The yeast Rat1 exonuclease promotes transcription termination by RNA polymerase II. | Q27934493 | ||
The end of the message: multiple protein-RNA interactions define the mRNA polyadenylation site | Q28082339 | ||
The BARD1-CstF-50 interaction links mRNA 3' end formation to DNA damage and tumor suppression | Q28205420 | ||
Transcription factor TFIID recruits factor CPSF for formation of 3' end of mRNA | Q28249862 | ||
Polyadenylation factor CPSF-73 is the pre-mRNA 3'-end-processing endonuclease | Q28275724 | ||
A unifying genetic model for facioscapulohumeral muscular dystrophy | Q28291033 | ||
Expression of two protein isoforms of PAX7 is controlled by competing cleavage-polyadenylation and splicing | Q28291809 | ||
The polyadenylation factor CstF-64 regulates alternative processing of IgM heavy chain pre-mRNA during B cell differentiation | Q28298568 | ||
The C-terminal domain of RNA polymerase II couples mRNA processing to transcription | Q28301744 | ||
Formation of mRNA 3' ends in eukaryotes: mechanism, regulation, and interrelationships with other steps in mRNA synthesis | Q28609911 | ||
5'-Capping enzymes are targeted to pre-mRNA by binding to the phosphorylated carboxy-terminal domain of RNA polymerase II | Q28623635 | ||
U1 snRNP protects pre-mRNAs from premature cleavage and polyadenylation | Q29032058 | ||
RNA transcripts, miRNA-sized fragments and proteins produced from D4Z4 units: new candidates for the pathophysiology of facioscapulohumeral dystrophy | Q29036117 | ||
Digenic inheritance of an SMCHD1 mutation and an FSHD-permissive D4Z4 allele causes facioscapulohumeral muscular dystrophy type 2 | Q29303884 | ||
DUX4 and DUX4 downstream target genes are expressed in fetal FSHD muscles | Q29391941 | ||
RNA polymerase II and the integration of nuclear events | Q29614772 | ||
RNA polymerase II is an essential mRNA polyadenylation factor | Q29614773 | ||
Mechanism and regulation of mRNA polyadenylation | Q29614774 | ||
Chromosome 4q DNA rearrangements associated with facioscapulohumeral muscular dystrophy | Q30039698 | ||
Ligand-independent androgen receptor variants derived from splicing of cryptic exons signify hormone-refractory prostate cancer | Q30485336 | ||
Heterogeneity in polyadenylation cleavage sites in mammalian mRNA sequences: implications for SAGE analysis. | Q30663306 | ||
A downstream polyadenylation element in human papillomavirus type 16 L2 encodes multiple GGG motifs and interacts with hnRNP H. | Q30789709 | ||
Aberrant herpesvirus-induced polyadenylation correlates with cellular messenger RNA destruction | Q30863867 | ||
A comprehensive analysis of 3' end sequencing data sets reveals novel polyadenylation signals and the repressive role of heterogeneous ribonucleoprotein C on cleavage and polyadenylation | Q31112743 | ||
Reprogramming of 3' untranslated regions of mRNAs by alternative polyadenylation in generation of pluripotent stem cells from different cell types | Q33520920 | ||
Human skeletal muscle xenograft as a new preclinical model for muscle disorders | Q33649287 | ||
Loss of nuclear poly(A)-binding protein 1 causes defects in myogenesis and mRNA biogenesis. | Q33697689 | ||
Upper girdle imaging in facioscapulohumeral muscular dystrophy | Q33763548 | ||
Global analyses of the effect of different cellular contexts on microRNA targeting | Q33773060 | ||
Molecular mechanisms of eukaryotic pre-mRNA 3' end processing regulation | Q33871092 | ||
Contractions of D4Z4 on 4qB subtelomeres do not cause facioscapulohumeral muscular dystrophy. | Q33910577 | ||
Molecular basis of myotonic dystrophy: expansion of a trinucleotide (CTG) repeat at the 3' end of a transcript encoding a protein kinase family member. | Q33968674 | ||
Regulation of alternative polyadenylation by genomic imprinting | Q34011433 | ||
CFIm25 links alternative polyadenylation to glioblastoma tumour suppression. | Q34027447 | ||
Synthesis of secreted and membrane-bound immunoglobulin mu heavy chains is directed by mRNAs that differ at their 3' ends | Q34056363 | ||
DUX4-induced gene expression is the major molecular signature in FSHD skeletal muscle | Q34211798 | ||
An RNA polymerase pause site is associated with the immunoglobulin mus poly(A) site | Q34283461 | ||
RBBP6 isoforms regulate the human polyadenylation machinery and modulate expression of mRNAs with AU-rich 3' UTRs | Q34360775 | ||
Expanded CUG repeat RNAs form hairpins that activate the double-stranded RNA-dependent protein kinase PKR | Q34362347 | ||
Rules of engagement: co-transcriptional recruitment of pre-mRNA processing factors | Q34419716 | ||
CPSF30 and Wdr33 directly bind to AAUAAA in mammalian mRNA 3' processing | Q34430715 | ||
Reconstitution of CPSF active in polyadenylation: recognition of the polyadenylation signal by WDR33. | Q34430722 | ||
Interactions of CstF-64, CstF-77, and symplekin: implications on localisation and function. | Q34471019 | ||
Loss of MBNL leads to disruption of developmentally regulated alternative polyadenylation in RNA-mediated disease. | Q34473863 | ||
Downstream elements of mammalian pre-mRNA polyadenylation signals: primary, secondary and higher-order structures. | Q34759787 | ||
Cleavage site determinants min the mammalian polydenylation signal | Q34762164 | ||
Splicing factor ASF/SF2 and transcription factor PPAR-gamma cooperate to directly regulate transcription of uncoupling protein-3. | Q34900774 | ||
RNA polymerase II kinetics in polo polyadenylation signal selection. | Q35048913 | ||
The nucleosome regulates the usage of polyadenylation sites in the human genome | Q35074663 | ||
Systematic profiling of poly(A)+ transcripts modulated by core 3' end processing and splicing factors reveals regulatory rules of alternative cleavage and polyadenylation | Q35532398 | ||
Structure and function of poly(A) binding proteins | Q35781035 | ||
A quantitative atlas of polyadenylation in five mammals | Q36021683 | ||
Implications of polyadenylation in health and disease | Q36189648 | ||
GC skew defines distinct RNA polymerase pause sites in CpG island promoters | Q36199553 | ||
Poly(A) binding protein nuclear 1 levels affect alternative polyadenylation | Q36305636 | ||
Subcellular RNA profiling links splicing and nuclear DICER1 to alternative cleavage and polyadenylation. | Q36406071 | ||
Transcriptome-wide analyses of CstF64-RNA interactions in global regulation of mRNA alternative polyadenylation | Q36414738 | ||
Analysis of alternative cleavage and polyadenylation by 3' region extraction and deep sequencing. | Q36575994 | ||
P275 | copyright license | Creative Commons Attribution | Q6905323 |
P6216 | copyright status | copyrighted | Q50423863 |
P433 | issue | 5 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | messenger RNA | Q188928 |
gene silencing | Q1431332 | ||
P577 | publication date | 2018-05-03 | |
P1433 | published in | International Journal of Molecular Sciences | Q3153277 |
P1476 | title | Targeting the Polyadenylation Signal of Pre-mRNA: A New Gene Silencing Approach for Facioscapulohumeral Dystrophy. | |
P478 | volume | 19 |
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