PTEN mutation analysis in two genetic subtypes of high-grade oligodendroglial tumors. PTEN is only occasionally mutated in one of the two genetic subtypes.

scientific article published in May 2000

PTEN mutation analysis in two genetic subtypes of high-grade oligodendroglial tumors. PTEN is only occasionally mutated in one of the two genetic subtypes. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/S0165-4608(99)00210-1
P698PubMed publication ID10812170

P2093author name stringH Kremer
J J van Overbeeke
R H Boerman
H Vermeer
J W Jeuken
M R Nelen
W C van Staveren
P2860cites workGermline mutations in PTEN are present in Bannayan-Zonana syndromeQ48046915
Mutational analysis of the PTEN gene in gliomas: molecular and pathological correlationsQ48252490
Molecular genetic evidence for subtypes of oligoastrocytomas.Q48607827
New deletion in low-grade oligodendroglioma at the glioblastoma suppressor locus on chromosome 10q25-26.Q48636243
Oligodendrogliomas. Part II: A new grading system based on morphological and imaging criteriaQ48654914
Oligodendrogliomas. Part I: Patterns of growth, histological diagnosis, clinical and imaging correlations: a study of 153 cases.Q48654928
Identification of subgroups of high-grade oligodendroglial tumors by comparative genomic hybridization.Q55476866
PTEN/MMAC1 mutations in primary glioblastomas and short-term cultures of malignant gliomas.Q55477977
Genetic reflection of glioblastoma biopsy material in xenografts: characterization of 11 glioblastoma xenograft lines by comparative genomic hybridizationQ60536668
Malignant potential of murine stromal cells after transplantation of human tumors into nude miceQ70708626
Two tumor suppressive loci on chromosome 10 involved in human glioblastomasQ71695102
PTEN germ-line mutations in juvenile polyposis coliQ74026971
Novel PTEN mutations in patients with Cowden disease: absence of clear genotype-phenotype correlationsQ77421649
DMBT1, a new member of the SRCR superfamily, on chromosome 10q25.3-26.1 is deleted in malignant brain tumoursQ24310338
The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphateQ24317714
Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTENQ24322051
P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphataseQ24322705
PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancerQ27860985
A simple salting out procedure for extracting DNA from human nucleated cellsQ27861086
A highly conserved processed PTEN pseudogene is located on chromosome band 9p21Q28273178
Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancersQ28306997
Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTENQ28513537
Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndromeQ29615538
Rapid and sensitive detection of point mutations and DNA polymorphisms using the polymerase chain reactionQ29618515
Comparative genomic hybridization for molecular cytogenetic analysis of solid tumorsQ29618818
Germline mutations in the PTEN/MMAC1 gene in patients with Cowden disease.Q34742581
Inherited mutations in PTEN that are associated with breast cancer, cowden disease, and juvenile polyposisQ35250337
Vascularity and perfusion of human gliomas xenografted in the athymic nude mouseQ36080718
Genetic aberrations in human brain tumorsQ40659282
Molecular pathways in the formation of gliomas.Q40961534
Phenotypic analysis of human glioma cells expressing the MMAC1 tumor suppressor phosphataseQ40972780
PTEN: sometimes taking it off can be better than putting it on.Q43104730
PTEN (MMAC1) mutations are frequent in primary glioblastomas (de novo) but not in secondary glioblastomasQ47740646
Somatic deletion mapping on chromosome 10 and sequence analysis of PTEN/MMAC1 point to the 10q25-26 region as the primary target in low-grade and high-grade gliomasQ47775705
PTEN mutations in gliomas and glioneuronal tumors.Q47995275
P433issue1
P921main subjectoligodendrocyteQ916698
P304page(s)42-47
P577publication date2000-05-01
P1433published inCancer Genetics and CytogeneticsQ15753061
P1476titlePTEN mutation analysis in two genetic subtypes of high-grade oligodendroglial tumors. PTEN is only occasionally mutated in one of the two genetic subtypes.
P478volume119

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cites work (P2860)
Q48125887Clinical utility of fluorescence in situ hybridization (FISH) in morphologically ambiguous gliomas with hybrid oligodendroglial/astrocytic features
Q34566430Genetics of brain neoplasms
Q34480154Genetics of nervous system tumors
Q48172557Loss of heterozygosity for loci on chromosome arms 1p and 10q in oligodendroglial tumors: relationship to outcome and chemosensitivity
Q33410196Molecular analysis of anaplastic oligodendroglial tumors in a prospective randomized study: A report from EORTC study 26951.
Q33183924New perspectives for the diagnosis and treatment of oligodendroglioma.
Q48591255PIK3CA mutations in oligodendroglial tumours.
Q35868124Pathology and molecular genetics of oligodendroglial tumors
Q30391301Structural mutation analysis of PTEN and its genotype-phenotype correlations in endometriosis and cancer

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