B cells are capable of independently eliciting rapid reactivation of encephalitogenic CD4 T cells in a murine model of multiple sclerosis.

scientific article published on 26 June 2018

B cells are capable of independently eliciting rapid reactivation of encephalitogenic CD4 T cells in a murine model of multiple sclerosis. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1371/JOURNAL.PONE.0199694
P932PMC publication ID6019098
P698PubMed publication ID29944721

P50authorChelsea R Parker HarpQ49336637
Gregory F WuQ88637202
P2093author name stringMark J Shlomchik
John H Russell
Julia Sim
Angela S Archambault
P2860cites workOcrelizumab versus Interferon Beta-1a in Relapsing Multiple SclerosisQ40400262
Proinflammatory GM-CSF-producing B cells in multiple sclerosis and B cell depletion therapyQ40404169
Receptor-mediated B cell antigen processing. Increased antigenicity of a globular protein covalently coupled to antibodies specific for B cell surface structuresQ41902663
B cell antigen presentation in the initiation of follicular helper T cell and germinal center differentiationQ41968057
Tertiary lymphoid organ development coincides with determinant spreading of the myelin-specific T cell responseQ43887998
Antibodies to sulfatide in cerebrospinal fluid of patients with multiple sclerosisQ44473356
Rat and human myelin oligodendrocyte glycoproteins induce experimental autoimmune encephalomyelitis by different mechanisms in C57BL/6 miceQ44484576
B cells from patients with multiple sclerosis induce cell death via apoptosis in neurons in vitroQ45061123
Rituximab in relapsing-remitting multiple sclerosis: a 72-week, open-label, phase I trialQ45119459
Lipid microarrays identify key mediators of autoimmune brain inflammationQ46845275
Activated B Cells Participating in the Anti-Myelin Response Are Excluded from the Inflamed Central Nervous System in a Model of Autoimmunity that Allows for B Cell Recognition of AutoantigenQ48325814
B-cell-deficient mice develop experimental allergic encephalomyelitis with demyelination after myelin oligodendrocyte glycoprotein sensitizationQ48364459
Short-lived plasma blasts are the main B cell effector subset during the course of multiple sclerosisQ48949365
Intracerebral expression of CXCL13 and BAFF is accompanied by formation of lymphoid follicle-like structures in the meninges of mice with relapsing experimental autoimmune encephalomyelitis.Q51027456
Abnormal B-cell cytokine responses a trigger of T-cell-mediated disease in MS?Q57041523
Antigen-specific interaction between T and B cellsQ59063745
B cells are critical to induction of experimental allergic encephalomyelitis by protein but not by a short encephalitogenic peptideQ73170385
A Conformational Study of the Human and Rat Encephalitogenic Myelin Oligodendrocyte Glycoprotein Peptides 35–55Q73483126
Dendritic cells in inflammatory responses in the CNSQ73672190
Rituximab in a patient with multiple sclerosis--effect on B cells, plasma cells and intrathecal IgG synthesisQ79930770
Impact of myelin-specific antigen presenting B cells on T cell activation in multiple sclerosisQ81575313
Cytokine-Defined B Cell Responses as Therapeutic Targets in Multiple SclerosisQ26771459
B-cell depletion with rituximab in relapsing-remitting multiple sclerosisQ28268626
Multiple sclerosisQ28299151
B cell receptor signal transduction in the GC is short-circuited by high phosphatase activityQ28680673
Autoimmune T cell responses in the central nervous systemQ33620003
Immunoglobulin class-switched B cells form an active immune axis between CNS and periphery in multiple sclerosis.Q34251673
Germinal center selection and the development of memory B and plasma cellsQ34268133
Experimental autoimmune encephalomyelitis induction in genetically B cell-deficient miceQ34411828
CD11c/EYFP transgene illuminates a discrete network of dendritic cells within the embryonic, neonatal, adult, and injured mouse brainQ34590006
Limited sufficiency of antigen presentation by dendritic cells in models of central nervous system autoimmunity.Q34645411
Spontaneous opticospinal encephalomyelitis in a double-transgenic mouse model of autoimmune T cell/B cell cooperation.Q35009513
Myelin oligodendrocyte glycoprotein-specific T and B cells cooperate to induce a Devic-like disease in miceQ35009518
B cells populating the multiple sclerosis brain mature in the draining cervical lymph nodesQ35298764
B-cell very late antigen-4 deficiency reduces leukocyte recruitment and susceptibility to central nervous system autoimmunity.Q35514450
Rituximab reduces B cells and T cells in cerebrospinal fluid of multiple sclerosis patientsQ35585366
B cell antigen presentation is sufficient to drive neuroinflammation in an animal model of multiple sclerosisQ35613006
Lipid arrays identify myelin-derived lipids and lipid complexes as prominent targets for oligoclonal band antibodies in multiple sclerosisQ36104857
Th17 cells induce ectopic lymphoid follicles in central nervous system tissue inflammationQ36174679
Optic Neuritis, A New Variant of Experimental Encephalomyelitis, A Durable Model for All Seasons, Now In Its Seventieth YearQ36370956
Regulatory B cells control T-cell autoimmunity through IL-21-dependent cognate interactions.Q36385029
B cell exchange across the blood-brain barrier in multiple sclerosisQ36498036
CNS accumulation of regulatory B cells is VLA-4-dependentQ36694494
Cutting Edge: Integrin α4 Is Required for Regulatory B Cell Control of Experimental Autoimmune EncephalomyelitisQ36905571
Antigen specificity of clonally expanded and receptor edited cerebrospinal fluid B cells from patients with relapsing remitting MSQ37258223
Spontaneous relapsing-remitting EAE in the SJL/J mouse: MOG-reactive transgenic T cells recruit endogenous MOG-specific B cells.Q37273211
MHC class II-dependent B cell APC function is required for induction of CNS autoimmunity independent of myelin-specific antibodiesQ37397820
B cells promote induction of experimental autoimmune encephalomyelitis by facilitating reactivation of T cells in the central nervous systemQ37601825
Using EAE to better understand principles of immune function and autoimmune pathologyQ37657501
Receptor-mediated antigen uptake and its effect on antigen presentation to class II-restricted T lymphocytesQ37925555
Decisions about dendritic cells: past, present, and futureQ37963951
Cutting edge: Conditional MHC class II expression reveals a limited role for B cell antigen presentation in primary and secondary CD4 T cell responsesQ39138822
P275copyright licenseCreative Commons CC0 LicenseQ6938433
P6216copyright statuscopyrighted, dedicated to the public domain by copyright holderQ88088423
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectmultiple sclerosisQ8277
murine modelQ122890741
P304page(s)e0199694
P577publication date2018-06-26
P1433published inPLOS OneQ564954
P1476titleB cells are capable of independently eliciting rapid reactivation of encephalitogenic CD4 T cells in a murine model of multiple sclerosis.
P478volume13

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cites work (P2860)
Q91236273B cells in autoimmune and neurodegenerative central nervous system diseases
Q90471432Novel B cell-dependent multiple sclerosis model using extracellular domains of myelin proteolipid protein
Q61812996The Diversity of Encephalitogenic CD4+ T Cells in Multiple Sclerosis and Its Animal Models

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