Stuart A Nicklin

researcher

Stuart A Nicklin is …
instance of (P31):
humanQ5

External links are
P856official websitehttps://www.gla.ac.uk/researchinstitutes/icams/staff/stuartnicklin/
P496ORCID iD0000-0002-9691-6210

P69educated atUniversity of GlasgowQ192775
P108employerUniversity of GlasgowQ192775
P734family nameNicklinQ37247608
NicklinQ37247608
NicklinQ37247608
P735given nameStuartQ7626248
StuartQ7626248
P106occupationresearcherQ1650915
P21sex or gendermaleQ6581097

Reverse relations

author (P50)
Q58227792A Novel Mechanism of Action for Angiotensin-(1–7) via the Angiotensin Type 1 Receptor
Q35545274AAV-based gene transfer
Q36445557Ad5:Ad48 hexon hypervariable region substitutions lead to toxicity and increased inflammatory responses following intravenous delivery
Q40411990Adeno-associated virus (AAV)-7 and -8 poorly transduce vascular endothelial cells and are sensitive to proteasomal degradation.
Q34429431Adenoviral delivery of angiotensin-(1-7) or angiotensin-(1-9) inhibits cardiomyocyte hypertrophy via the mas or angiotensin type 2 receptor
Q40478824Adenoviral serotype 5 vectors pseudotyped with fibers from subgroup D show modified tropism in vitro and in vivo.
Q114231598Adenoviral vectors for cardiovascular gene therapy applications: a clinical and industry perspective
Q38305480Adenovirus 5 fibers mutated at the putative HSPG-binding site show restricted retargeting with targeting peptides in the HI loop
Q45875068Adenovirus serotype 5 hexon mediates liver gene transfer
Q38193206Angiotensin-(1-7) and angiotensin-(1-9): function in cardiac and vascular remodelling
Q28565979Angiotensin-(1-9) attenuates cardiac fibrosis in the stroke-prone spontaneously hypertensive rat via the angiotensin type 2 receptor
Q28566391Angiotensin1-9 antagonises pro-hypertrophic signalling in cardiomyocytes via the angiotensin type 2 receptor
Q41401817Antagonists of GPR35 display high species ortholog selectivity and varying modes of action
Q64092404Assessing the effects of Ang-(1-7) therapy following transient middle cerebral artery occlusion
Q39342777Biodistribution and inflammatory profiles of novel penton and hexon double-mutant serotype 5 adenoviruses
Q34282191Biodistribution and retargeting of FX-binding ablated adenovirus serotype 5 vectors
Q42261987Capsid modification strategies for detargeting adenoviral vectors
Q29397067Cardiac Hypertrophy Is Inhibited by a Local Pool of cAMP Regulated by Phosphodiesterase 2Novelty and Significance
Q35948498Cell-selective viral gene delivery vectors for the vasculature
Q39048039Combined therapeutic benefit of mitochondria-targeted antioxidant, MitoQ10, and angiotensin receptor blocker, losartan, on cardiovascular function.
Q33440718Defining a Novel Role for the Coxsackievirus and Adenovirus Receptor in Human Adenovirus Serotype 5 Transduction In Vitro in the Presence of Mouse Serum
Q33197377Development of efficient viral vectors selective for vascular smooth muscle cells
Q33286806Development of renal-targeted vectors through combined in vivo phage display and capsid engineering of adenoviral fibers from serotype 19p.
Q40528748Dual targeting of gene delivery by genetic modification of adenovirus serotype 5 fibers and cell-selective transcriptional control.
Q40528538Effect of adenovirus serotype 5 fiber and penton modifications on in vivo tropism in rats
Q39926337Effect of neutralizing sera on factor x-mediated adenovirus serotype 5 gene transfer
Q58227795Efficient Vascular Endothelial Gene Transfer Following Intravenous Adenovirus Delivery
Q38901143Efficient transduction of primary vascular cells by the rare adenovirus serotype 49 vector
Q38502124Electrical consequences of cardiac myocyte: fibroblast coupling
Q40051540Engineering adeno-associated virus 2 vectors for targeted gene delivery to atherosclerotic lesions.
Q40431364Enhanced gene transfer activity of peptide-targeted gene-delivery vectors
Q42146790FX and host defense evasion tactics by adenovirus
Q38389922G protein-coupled receptor 35: an emerging target in inflammatory and cardiovascular disease
Q37122933G-Protein-Coupled Receptor 35 Mediates Human Saphenous Vein Vascular Smooth Muscle Cell Migration and Endothelial Cell Proliferation
Q39799967GPR35 as a Novel Therapeutic Target.
Q39097850Gene Therapy With Angiotensin-(1-9) Preserves Left Ventricular Systolic Function After Myocardial Infarction
Q29417122Genome-wide association study of blood pressure extremes identifies variant near UMOD associated with hypertension
Q91714392Human Adenovirus Serotype 5 Is Sensitive to IgM-Independent Neutralization In Vitro and In Vivo
Q37291653Identification of coagulation factor (F)X binding sites on the adenovirus serotype 5 hexon: effect of mutagenesis on FX interactions and gene transfer
Q40822981Identification of peptides that target the endothelial cell-specific LOX-1 receptor.
Q38343485In vitro and in vivo characterisation of endothelial cell selective adenoviral vectors.
Q39502394Influence of coagulation factor x on in vitro and in vivo gene delivery by adenovirus (Ad) 5, Ad35, and chimeric Ad5/Ad35 vectors
Q41900381Influence of coagulation factor zymogens on the infectivity of adenoviruses pseudotyped with fibers from subgroup D.
Q37284881Interactions of adenovirus vectors with blood: implications for intravascular gene therapy applications.
Q35557004Manipulating adenovirus hexon hypervariable loops dictates immune neutralisation and coagulation factor X-dependent cell interaction in vitro and in vivo
Q42805327Mouse adenovirus type 1 and human adenovirus type 5 differ in endothelial cell tropism and liver targeting
Q40264847Multiple vitamin K-dependent coagulation zymogens promote adenovirus-mediated gene delivery to hepatocytes
Q36842711Novel vectors for in vivo gene delivery to vascular tissue
Q46120246Onset of experimental severe cardiac fibrosis is mediated by overexpression of Angiotensin-converting enzyme 2.
Q47420905Overexpression of p53 increases lumen size and blocks neointima formation in porcine interposition vein grafts
Q38026374Prevention of coronary in-stent restenosis and vein graft failure: does vascular gene therapy have a role?
Q35698680Promoters and control elements: designing expression cassettes for gene therapy.
Q38069197Regulation of cardiovascular remodeling by the counter-regulatory axis of the renin-angiotensin system
Q28475714Requirements for receptor engagement during infection by adenovirus complexed with blood coagulation factor X
Q38866016Retargeting FX-binding-ablated HAdV-5 to vascular cells by inclusion of the RGD-4C peptide in hexon hypervariable region 7 and the HI loop
Q47613009Runx1 Deficiency Protects Against Adverse Cardiac Remodeling After Myocardial Infarction.
Q45876086Special focus issue on the annual meeting of the British Society for Gene and Cell Therapy
Q64947025Systems biology identifies cytosolic PLA2 as a target in vascular calcification treatment.
Q31036743Targeted gene delivery to vascular tissue in vivo by tropism-modified adeno-associated virus vectors
Q35095393Targeting gene therapy vectors to the vascular endothelium
Q42152828Targeting of adenovirus serotype 5 (Ad5) and 5/47 pseudotyped vectors in vivo: fundamental involvement of coagulation factors and redundancy of CAR binding by Ad5.
Q58227789The Orphan Receptor GPR35 Contributes to Angiotensin II-Induced Hypertension and Cardiac Dysfunction in Mice
Q37405405The antiallergic mast cell stabilizers lodoxamide and bufrolin as the first high and equipotent agonists of human and rat GPR35
Q58227799The frequency of hemochromatosis-associated alleles is increased in British patients with sporadic porphyria cutanea tarda
Q58227800The frequency of the haemochromatosis-associated genotype D6S265-1:D6S105-8 in blood donors
Q38230901The importance of coagulation factors binding to adenovirus: historical perspectives and implications for gene delivery
Q36182171The influence of adenovirus fiber structure and function on vector development for gene therapy
Q37085147The relevance of coagulation factor X protection of adenoviruses in human sera.
Q34207550Third-generation lentivirus vectors efficiently transduce and phenotypically modify vascular cells: implications for gene therapy
Q45870079Transductional and transcriptional targeting of cancer cells using genetically engineered viral vectors
Q38614156Tropism-modification strategies for targeted gene delivery using adenoviral vectors
Q34791438Tropism-modified adenoviral and adeno-associated viral vectors for gene therapy
Q33456433Use of in vivo phage display to engineer novel adenoviruses for targeted delivery to the cardiac vasculature
Q40655242Use of phage display to identify novel peptides for targeted gene therapy
Q58227790Utilizing proteomics to understand and define hypertension: where are we and where do we go?
Q33230629Vascular bed-targeted in vivo gene delivery using tropism-modified adeno-associated viruses
Q44631683Vector systems for prenatal gene therapy: principles of adenovirus design and production