human | Q5 |
P856 | official website | https://www.gla.ac.uk/researchinstitutes/icams/staff/stuartnicklin/ |
P496 | ORCID iD | 0000-0002-9691-6210 |
P69 | educated at | University of Glasgow | Q192775 |
P108 | employer | University of Glasgow | Q192775 |
P734 | family name | Nicklin | Q37247608 |
Nicklin | Q37247608 | ||
Nicklin | Q37247608 | ||
P735 | given name | Stuart | Q7626248 |
Stuart | Q7626248 | ||
P106 | occupation | researcher | Q1650915 |
P21 | sex or gender | male | Q6581097 |
Q58227792 | A Novel Mechanism of Action for Angiotensin-(1–7) via the Angiotensin Type 1 Receptor |
Q35545274 | AAV-based gene transfer |
Q36445557 | Ad5:Ad48 hexon hypervariable region substitutions lead to toxicity and increased inflammatory responses following intravenous delivery |
Q40411990 | Adeno-associated virus (AAV)-7 and -8 poorly transduce vascular endothelial cells and are sensitive to proteasomal degradation. |
Q34429431 | Adenoviral delivery of angiotensin-(1-7) or angiotensin-(1-9) inhibits cardiomyocyte hypertrophy via the mas or angiotensin type 2 receptor |
Q40478824 | Adenoviral serotype 5 vectors pseudotyped with fibers from subgroup D show modified tropism in vitro and in vivo. |
Q114231598 | Adenoviral vectors for cardiovascular gene therapy applications: a clinical and industry perspective |
Q38305480 | Adenovirus 5 fibers mutated at the putative HSPG-binding site show restricted retargeting with targeting peptides in the HI loop |
Q45875068 | Adenovirus serotype 5 hexon mediates liver gene transfer |
Q38193206 | Angiotensin-(1-7) and angiotensin-(1-9): function in cardiac and vascular remodelling |
Q28565979 | Angiotensin-(1-9) attenuates cardiac fibrosis in the stroke-prone spontaneously hypertensive rat via the angiotensin type 2 receptor |
Q28566391 | Angiotensin1-9 antagonises pro-hypertrophic signalling in cardiomyocytes via the angiotensin type 2 receptor |
Q41401817 | Antagonists of GPR35 display high species ortholog selectivity and varying modes of action |
Q64092404 | Assessing the effects of Ang-(1-7) therapy following transient middle cerebral artery occlusion |
Q39342777 | Biodistribution and inflammatory profiles of novel penton and hexon double-mutant serotype 5 adenoviruses |
Q34282191 | Biodistribution and retargeting of FX-binding ablated adenovirus serotype 5 vectors |
Q42261987 | Capsid modification strategies for detargeting adenoviral vectors |
Q29397067 | Cardiac Hypertrophy Is Inhibited by a Local Pool of cAMP Regulated by Phosphodiesterase 2Novelty and Significance |
Q35948498 | Cell-selective viral gene delivery vectors for the vasculature |
Q39048039 | Combined therapeutic benefit of mitochondria-targeted antioxidant, MitoQ10, and angiotensin receptor blocker, losartan, on cardiovascular function. |
Q33440718 | Defining a Novel Role for the Coxsackievirus and Adenovirus Receptor in Human Adenovirus Serotype 5 Transduction In Vitro in the Presence of Mouse Serum |
Q33197377 | Development of efficient viral vectors selective for vascular smooth muscle cells |
Q33286806 | Development of renal-targeted vectors through combined in vivo phage display and capsid engineering of adenoviral fibers from serotype 19p. |
Q40528748 | Dual targeting of gene delivery by genetic modification of adenovirus serotype 5 fibers and cell-selective transcriptional control. |
Q40528538 | Effect of adenovirus serotype 5 fiber and penton modifications on in vivo tropism in rats |
Q39926337 | Effect of neutralizing sera on factor x-mediated adenovirus serotype 5 gene transfer |
Q58227795 | Efficient Vascular Endothelial Gene Transfer Following Intravenous Adenovirus Delivery |
Q38901143 | Efficient transduction of primary vascular cells by the rare adenovirus serotype 49 vector |
Q38502124 | Electrical consequences of cardiac myocyte: fibroblast coupling |
Q40051540 | Engineering adeno-associated virus 2 vectors for targeted gene delivery to atherosclerotic lesions. |
Q40431364 | Enhanced gene transfer activity of peptide-targeted gene-delivery vectors |
Q42146790 | FX and host defense evasion tactics by adenovirus |
Q38389922 | G protein-coupled receptor 35: an emerging target in inflammatory and cardiovascular disease |
Q37122933 | G-Protein-Coupled Receptor 35 Mediates Human Saphenous Vein Vascular Smooth Muscle Cell Migration and Endothelial Cell Proliferation |
Q39799967 | GPR35 as a Novel Therapeutic Target. |
Q39097850 | Gene Therapy With Angiotensin-(1-9) Preserves Left Ventricular Systolic Function After Myocardial Infarction |
Q29417122 | Genome-wide association study of blood pressure extremes identifies variant near UMOD associated with hypertension |
Q91714392 | Human Adenovirus Serotype 5 Is Sensitive to IgM-Independent Neutralization In Vitro and In Vivo |
Q37291653 | Identification of coagulation factor (F)X binding sites on the adenovirus serotype 5 hexon: effect of mutagenesis on FX interactions and gene transfer |
Q40822981 | Identification of peptides that target the endothelial cell-specific LOX-1 receptor. |
Q38343485 | In vitro and in vivo characterisation of endothelial cell selective adenoviral vectors. |
Q39502394 | Influence of coagulation factor x on in vitro and in vivo gene delivery by adenovirus (Ad) 5, Ad35, and chimeric Ad5/Ad35 vectors |
Q41900381 | Influence of coagulation factor zymogens on the infectivity of adenoviruses pseudotyped with fibers from subgroup D. |
Q37284881 | Interactions of adenovirus vectors with blood: implications for intravascular gene therapy applications. |
Q35557004 | Manipulating adenovirus hexon hypervariable loops dictates immune neutralisation and coagulation factor X-dependent cell interaction in vitro and in vivo |
Q42805327 | Mouse adenovirus type 1 and human adenovirus type 5 differ in endothelial cell tropism and liver targeting |
Q40264847 | Multiple vitamin K-dependent coagulation zymogens promote adenovirus-mediated gene delivery to hepatocytes |
Q36842711 | Novel vectors for in vivo gene delivery to vascular tissue |
Q46120246 | Onset of experimental severe cardiac fibrosis is mediated by overexpression of Angiotensin-converting enzyme 2. |
Q47420905 | Overexpression of p53 increases lumen size and blocks neointima formation in porcine interposition vein grafts |
Q38026374 | Prevention of coronary in-stent restenosis and vein graft failure: does vascular gene therapy have a role? |
Q35698680 | Promoters and control elements: designing expression cassettes for gene therapy. |
Q38069197 | Regulation of cardiovascular remodeling by the counter-regulatory axis of the renin-angiotensin system |
Q28475714 | Requirements for receptor engagement during infection by adenovirus complexed with blood coagulation factor X |
Q38866016 | Retargeting FX-binding-ablated HAdV-5 to vascular cells by inclusion of the RGD-4C peptide in hexon hypervariable region 7 and the HI loop |
Q47613009 | Runx1 Deficiency Protects Against Adverse Cardiac Remodeling After Myocardial Infarction. |
Q45876086 | Special focus issue on the annual meeting of the British Society for Gene and Cell Therapy |
Q64947025 | Systems biology identifies cytosolic PLA2 as a target in vascular calcification treatment. |
Q31036743 | Targeted gene delivery to vascular tissue in vivo by tropism-modified adeno-associated virus vectors |
Q35095393 | Targeting gene therapy vectors to the vascular endothelium |
Q42152828 | Targeting of adenovirus serotype 5 (Ad5) and 5/47 pseudotyped vectors in vivo: fundamental involvement of coagulation factors and redundancy of CAR binding by Ad5. |
Q58227789 | The Orphan Receptor GPR35 Contributes to Angiotensin II-Induced Hypertension and Cardiac Dysfunction in Mice |
Q37405405 | The antiallergic mast cell stabilizers lodoxamide and bufrolin as the first high and equipotent agonists of human and rat GPR35 |
Q58227799 | The frequency of hemochromatosis-associated alleles is increased in British patients with sporadic porphyria cutanea tarda |
Q58227800 | The frequency of the haemochromatosis-associated genotype D6S265-1:D6S105-8 in blood donors |
Q38230901 | The importance of coagulation factors binding to adenovirus: historical perspectives and implications for gene delivery |
Q36182171 | The influence of adenovirus fiber structure and function on vector development for gene therapy |
Q37085147 | The relevance of coagulation factor X protection of adenoviruses in human sera. |
Q34207550 | Third-generation lentivirus vectors efficiently transduce and phenotypically modify vascular cells: implications for gene therapy |
Q45870079 | Transductional and transcriptional targeting of cancer cells using genetically engineered viral vectors |
Q38614156 | Tropism-modification strategies for targeted gene delivery using adenoviral vectors |
Q34791438 | Tropism-modified adenoviral and adeno-associated viral vectors for gene therapy |
Q33456433 | Use of in vivo phage display to engineer novel adenoviruses for targeted delivery to the cardiac vasculature |
Q40655242 | Use of phage display to identify novel peptides for targeted gene therapy |
Q58227790 | Utilizing proteomics to understand and define hypertension: where are we and where do we go? |
Q33230629 | Vascular bed-targeted in vivo gene delivery using tropism-modified adeno-associated viruses |
Q44631683 | Vector systems for prenatal gene therapy: principles of adenovirus design and production |