The E3 ligase HACE1 is a critical chromosome 6q21 tumor suppressor involved in multiple cancers

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The E3 ligase HACE1 is a critical chromosome 6q21 tumor suppressor involved in multiple cancers is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/NM1621
P698PubMed publication ID17694067
P5875ResearchGate publication ID6145608

P50authorJosef PenningerQ1674391
Maureen O'SullivanQ62579170
Hiromitsu HaraQ114428367
Renu SaraoQ114577344
Michael S AnglesioQ50613362
Jason E FarrarQ55691936
Shane CroninQ57904186
P2093author name stringGe Yang
Teiji Wada
Nataliya Melnyk
Fan Zhang
Liyong Zhang
Peter P Liu
Robert J Arceci
Poul H Sorensen
Mai P Nghiem
Liheng Li
P2860cites workA family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligaseQ24313174
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Molecular analysis of region t(5;6)(q21;q21) in Wilms tumorQ73048152
A 3-cM commonly deleted region in 6q21 in leukemias and lymphomas delineated by fluorescence in situ hybridizationQ73189650
Detection of frequent allelic loss of 6q23-q25.2 in microdissected human breast cancer tissuesQ73363385
Deletion mapping of the long arm of chromosome 6 in peripheral T and NK cell lymphomasQ76307740
Mucinous cancers have fewer genomic alterations than more common classes of breast cancerQ78601846
Allelotype analysis in relapsed childhood acute lymphoblastic leukemiaQ79133960
Allelic loss of chromosome 6q in gastric carcinomaQ79324191
Ductal carcinoma in situ of the breast with different histopathological grades and corresponding new breast tumour events: analysis of loss of heterozygosityQ81680858
The epigenomics of cancerQ28289975
Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localizationQ28290083
One Hundred and Twenty-Seven Cultured Human Tumor Cell Lines Producing Tumors in Nude Mice23Q28294341
Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumoursQ29547697
Defining the region(s) of deletion at 6q16-q22 in human prostate cancerQ30309336
Association of poor prognosis with loss of 12q, 17p, and 18q, and concordant loss of 6q/17p and 12q/18q in human pancreatic ductal adenocarcinomaQ30907534
BiQ Analyzer: visualization and quality control for DNA methylation data from bisulfite sequencing.Q31002908
Regulation of RasGRP via a phorbol ester-responsive C1 domain.Q31973953
Physical localisation of the breakpoints of a constitutional translocation t(5;6)(q21;q21) in a child with bilateral Wilms' tumour.Q33678730
To cycle or not to cycle: a critical decision in cancer.Q33957955
Expression of the ETV6-NTRK3 gene fusion as a primary event in human secretory breast carcinomaQ34160782
Loss of the cell cycle inhibitors p21(Cip1) and p27(Kip1) enhances tumorigenesis in knockout mouse modelsQ34162785
Spontaneous and carcinogen-induced tumorigenesis in p53-deficient mice.Q34347328
Loss of heterozygosity as a predictor to map tumor suppressor genes in cancer: molecular basis of its occurrenceQ34493845
Chromosome 6 suffers frequent and multiple aberrations in thymomaQ35789302
Putative tumor suppressor loci at 6q22 and 6q23-q24 are involved in the malignant progression of sporadic endocrine pancreatic tumorsQ35842229
Allelic imbalance of chromosome 6q in ovarian tumoursQ36080781
Detection of a novel t(6;15)(q21;q21) in a pediatric Wilms tumorQ38492004
Cloning and characterization of the common fragile site FRA6F harboring a replicative senescence gene and frequently deleted in human tumorsQ38495093
p27Kip1 and p21Cip1 Are Not Required for the Formation of Active D Cyclin-cdk4 ComplexesQ40015617
Differential expression of a novel ankyrin containing E3 ubiquitin-protein ligase, Hace1, in sporadic Wilms' tumor versus normal kidneyQ40535916
Genetic analysis of benign ovarian tumors.Q40592025
Serum hyaluronan and its association with unfavorable histology and aggressiveness of heterotransplanted Wilms' tumorQ40864996
Cdkn2a encodes functional variation of p16INK4a but not p19ARF, which confers selection in mouse lung tumorigenesisQ42814521
Loss of p16Ink4a with retention of p19Arf predisposes mice to tumorigenesisQ43729274
Absence of TSG101 transcript abnormalities in human cancersQ47886630
Mouse development and cell proliferation in the absence of D-cyclins.Q52088064
Genetic mapping of allelic loss on chromosome 6q within heterogeneous prostate carcinoma.Q53376016
Mapping of target regions of allelic loss in primary breast cancers to 1-cM intervals on genomic contigs at 6q21 and 6q25.3.Q55181109
The fundamental role of epigenetic events in cancerQ56421597
P433issue9
P407language of work or nameEnglishQ1860
P304page(s)1060-1069
P577publication date2007-08-12
P1433published inNature MedicineQ1633234
P1476titleThe E3 ligase HACE1 is a critical chromosome 6q21 tumor suppressor involved in multiple cancers
P478volume13

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cites work (P2860)
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