Calcium - a life and death signal

scientific article published in Nature

Calcium - a life and death signal is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1016044529
P356DOI10.1038/27094
P698PubMed publication ID9790183

P50authorMartin D BootmanQ40116729
P2093author name stringBerridge MJ
Lipp P
P2860cites workInositol trisphosphate and calcium signallingQ28262867
Role of the NF-ATc transcription factor in morphogenesis of cardiac valves and septumQ28508556
Calcium oscillations increase the efficiency and specificity of gene expressionQ29614728
Differential activation of transcription factors induced by Ca2+ response amplitude and durationQ29619010
Distinct functions of nuclear and cytoplasmic calcium in the control of gene expressionQ34413718
Interaction of Wnt and a Frizzled homologue triggers G-protein-linked phosphatidylinositol signallingQ38529495
Distinct aspects of neuronal differentiation encoded by frequency of spontaneous Ca2+ transientsQ46567447
Frequency modulation of Ca2+ sparks is involved in regulation of arterial diameter by cyclic nucleotides.Q48014718
Cell-cycle calcium transients driven by cyclic changes in inositol trisphosphate levelsQ59054543
P433issue6703
P407language of work or nameEnglishQ1860
P921main subjectcalciumQ706
P1104number of pages4
P304page(s)645-648
P577publication date1998-10-01
P1433published inNatureQ180445
P1476titleCalcium--a life and death signal
P478volume395

Reverse relations

cites work (P2860)
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Q42095947Differential expression of genes in the calcium-signaling pathway underlies lesion development in the LDb mouse model of atherosclerosis
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Q34412693Disturbed Ca2+ homeostasis increases glutaminyl cyclase expression; connecting two early pathogenic events in Alzheimer's disease in vitro
Q37642018Divergent Soybean Calmodulins Respond Similarly to Calcium Transients: Insight into Differential Target Regulation
Q46187669Diversity of voltage-dependent K+ channels in human pulmonary artery smooth muscle cells
Q90009702Dual dynamics of mitochondrial permeability transition pore opening
Q44231298Dual fatty acyl modification determines the localization and plasma membrane targeting of CBL/CIPK Ca2+ signaling complexes in Arabidopsis.
Q41952385Dual regulation of calcium mobilization by inositol 1,4, 5-trisphosphate in a living cell
Q28591132Ducky mouse phenotype of epilepsy and ataxia is associated with mutations in the Cacna2d2 gene and decreased calcium channel current in cerebellar Purkinje cells
Q46922116Dynamic expression patterns of zebrafish 1G5 (1G5z), a calmodulin kinase-like gene in the developing nervous system.
Q39719269Ecdysteroids elicit a rapid Ca2+ flux leading to Akt activation and increased protein synthesis in skeletal muscle cells
Q38939166Effect of bovine adenovirus 3 on mitochondria.
Q38445833Effect of human adipose tissue-derived mesenchymal-stem-cell bioactive materials on porcine embryo development
Q39719275Effect of ultrasonic exposure on Ca2+-ATPase activity in plasma membrane from Aloe arborescens callus cells
Q38435918Effect of vitrification on the mRNA transcriptome of bovine oocytes
Q40598753Effects of CaCl2 and MgCl2 on Fourier transform infrared spectra of lung cancer cells
Q42531948Effects of Low Amyloid-β (Aβ) Concentration on Aβ1-42 Oligomers Binding and GluN2B Membrane Expression
Q47153233Effects of Re-Vitrification of Mouse Morula and Early Blastocyst Stages on Apoptotic Gene Expression and Developmental Potential
Q28364342Effects of aldosterone on transient outward K+ current density in rat ventricular myocytes
Q82341156Effects of camptothecin, etoposide and Ca2+ on caspase-3 activity and myofibrillar disruption of chicken during postmortem ageing
Q35089938Effects of estrogen on brain development and neuroprotection--implications for negative symptoms in schizophrenia
Q33674286Effects of four kinds of electromagnetic fields (EMF) with different frequency spectrum bands on ovariectomized osteoporosis in mice
Q77530458Effects of noise on the off rate of Ca(2+) binding proteins in a coupled biochemical cell system
Q83094952Effects of phospholipids on the functional regulation of tBID in membranes
Q79442999Effects of rapid and slow cooling on thermoregulatory reactions in hypertensive rats after administration of calcium
Q54486263Effects of the Escherichia coli toxin cytolysin A on mucosal immunostimulation via epithelial Ca2+ signalling and Toll-like receptor 4.
Q40104319Electronic control of Ca2+ signalling in neuronal cells using an organic electronic ion pump
Q28572723Electrophysiological characterization and ionic stoichiometry of the rat brain K(+)-dependent NA(+)/CA(2+) exchanger, NCKX2
Q38973059Elevated receptor for activated C kinase 1 expression is involved in intracellular Ca2+ influx and potentially associated with compromised regulatory T cell function in patients with asthma
Q33339744Elucidating the mechanisms of cooperative calcium-calmodulin interactions: a structural systems biology approach.
Q43002879Encoding of progesterone stimulus intensity by intracellular [Ca2+] ([Ca2+]i) in human spermatozoa.
Q35735405Endogenous activation of metabotropic glutamate receptors in neocortical development causes neuronal calcium oscillations
Q34989433Endoplasmic reticulum (ER) stress: hepatitis C virus induces an ER-nucleus signal transduction pathway and activates NF-kappaB and STAT-3.
Q34240633Endoplasmic reticulum of animal cells and its organization into structural and functional domains
Q34104052Enhanced Orai1 and STIM1 expression as well as store operated Ca2+ entry in therapy resistant ovary carcinoma cells
Q48546084Enhanced ryanodine receptor recruitment contributes to Ca2+ disruptions in young, adult, and aged Alzheimer's disease mice.
Q50690364Enhanced ryanodine-mediated calcium release in mutant PS1-expressing Alzheimer's mouse models.
Q36281831Enhancement by Mg2+ of domain specificity in Ca2+-dependent interactions of calmodulin with target sequences
Q51657590Entropically modified spiking ability and periodicity in clustered channels
Q40736137Epidermal growth factor-mediated activation of the ETS domain transcription factor Elk-1 requires nuclear calcium
Q39670421Epigallocatechin-3-gallate increases intracellular [Ca2+] in U87 cells mainly by influx of extracellular Ca2+ and partly by release of intracellular stores
Q51896712Equality of average and steady-state levels in some nonlinear models of biological oscillations.
Q54525915Escherichia coli lacking the AcrAB multidrug efflux pump also lacks nonproteinaceous, PHB-polyphosphate Ca2+ channels in the membrane.
Q34465767Establishment of medium for laboratory cultivation and maintenance of Fredericella sultana for in vivo experiments with Tetracapsuloides bryosalmonae (Myxozoa)
Q44377088Ethanol-induced cephalic apoptosis requires phospholipase C-dependent intracellular calcium signaling
Q46302150Ethyl acetate fraction from methanol extraction of Vitis thunbergii var. taiwaniana induced G0 /G1 phase arrest via inhibition of cyclins D and E and induction of apoptosis through caspase-dependent and -independent pathways in human prostate carcin
Q30826490Evidence for Altered Ca(2+) Handling in Growth Associated Protein 43-Knockout Skeletal Muscle
Q40158034Evidence that calmodulin binding to the dopamine D2 receptor enhances receptor signaling
Q38307446Evolutionary physiology of bone: bone metabolism in changing environments.
Q42644751Exclusion of the Darier's disease gene, ATP2A2, as a common susceptibility gene for bipolar disorder
Q44185623Exercise training attenuates coronary smooth muscle phenotypic modulation and nuclear Ca2+ signaling
Q35983324Exogenous lactate infusion improved neurocognitive function of patients with mild traumatic brain injury
Q36119863Experimental Design for Stochastic Models of Nonlinear Signaling Pathways Using an Interval-Wise Linear Noise Approximation and State Estimation
Q46405254Experimental study of effect of corticosterone on primary cultured hippocampal neurons and their Ca2+/CaMKII expression
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Q36228381Expression of transient receptor potential channel 6 in cervical cancer
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Q35158887Fluorescence fluctuations and equivalence classes of Ca²⁺ imaging experiments.
Q34535350Fluorescent histochemical techniques for analysis of intracellular signaling
Q30582040Focal activation of cells by plasmon resonance assisted optical injection of signaling molecules
Q37403178Focal calcium monitoring with targeted nanosensors at the cytosolic side of endoplasmic reticulum.
Q54966356Force-Mediating Magnetic Nanoparticles to Engineer Neuronal Cell Function.
Q28571577Four tyrosine residues in phospholipase C-gamma 2, identified as Btk-dependent phosphorylation sites, are required for B cell antigen receptor-coupled calcium signaling
Q34564550Fraternal twins: Swiprosin-1/EFhd2 and Swiprosin-2/EFhd1, two homologous EF-hand containing calcium binding adaptor proteins with distinct functions
Q33736477Frequency and relative prevalence of calcium blips and puffs in a model of small IP₃R clusters
Q36701025From calcium blips to calcium puffs: theoretical analysis of the requirements for interchannel communication
Q37605806From puffs to global Ca2+ signals: how molecular properties shape global signals
Q24621422Functional properties of a new voltage-dependent calcium channel alpha(2)delta auxiliary subunit gene (CACNA2D2)
Q43553578Functional receptor-channel coupling compared in contractile and proliferative human vascular smooth muscle
Q35423938Functional switching of GABAergic synapses by ryanodine receptor activation
Q42910631G protein-coupled receptor Ca2+-linked mitochondrial reactive oxygen species are essential for endothelial/leukocyte adherence
Q52347058GSK-3β-mediated regulation of cadmium-induced cell death and survival.
Q36074089Gene Therapy Fully Restores Vision to the All-Cone Nrl(-/-) Gucy2e(-/-) Mouse Model of Leber Congenital Amaurosis-1.
Q28594817Gene knockout studies of Ca2+-transporting ATPases
Q98611555Generation of interconnected vesicles in a liposomal cell model
Q28139459Generic signals and specific outcomes: signaling through Ca2+, calcineurin, and NF-AT
Q33925318Genetic analysis of calcium spiking responses in nodulation mutants of Medicago truncatula
Q37686687Genetic polymorphisms of ORAI1 and chronic kidney disease in Taiwanese population
Q24675911Genomes at the interface between bacteria and organelles
Q27027531Ginseng ginsenoside pharmacology in the nervous system: involvement in the regulation of ion channels and receptors
Q36209242Ginseng pharmacology: a new paradigm based on gintonin-lysophosphatidic acid receptor interactions
Q42072404Ginseng saponins induce store-operated calcium entry in Xenopus oocytes
Q92357166Ginsenoside Rb1 exerts antiarrhythmic effects by inhibiting INa and ICaL in rabbit ventricular myocytes
Q37818509Ginsenosides and their CNS targets.
Q37031566Ginsenosides: are any of them candidates for drugs acting on the central nervous system?
Q45973238Global noise and oscillations in clustered excitable media.
Q39679201Global, synchronous oscillations in cytosolic calcium and adherence in bradykinin-stimulated Madin-Darby canine kidney cells
Q37361068Glutamate regulation of calcium and IP3 oscillating and pulsating dynamics in astrocytes
Q30832760Glycosides from edible sea cucumbers stimulate macrophages via purinergic receptors
Q33716082H-series protein kinase inhibitors and potential clinical applications
Q40927846HEK-293 cells possess a carbachol- and thapsigargin-sensitive intracellular Ca2+ store that is responsive to stop-flow medium changes and insensitive to caffeine and ryanodine
Q45741819Hepatitis B virus-related insertional mutagenesis implicates SERCA1 gene in the control of apoptosis
Q35804007Hesperidin inhibits HeLa cell proliferation through apoptosis mediated by endoplasmic reticulum stress pathways and cell cycle arrest
Q48655911High cytosolic free calcium level signals apoptosis through mitochondria-caspase mediated pathway in rat eggs cultured in vitro
Q34098400High levels of endorphin and related pathologies of veterinary concern. A review
Q30488677Highly thermosensitive Ca dynamics in a HeLa cell through IP(3) receptors
Q44330920Homocysteine-evoked 45Ca release in the rabbit hippocampus is mediated by both NMDA and group I metabotropic glutamate receptors: in vivo microdialysis study
Q92443990Host Calcium Channels and Pumps in Viral Infections
Q33933056Human hepatitis C virus NS5A protein alters intracellular calcium levels, induces oxidative stress, and activates STAT-3 and NF-kappa B.
Q104076497Human neurotropic polyomavirus, JC virus, agnoprotein targets mitochondrion and modulates its functions
Q35763597Human tumor cell proliferation evaluated using manganese-enhanced MRI.
Q40928760Hydrogen peroxide alters mitochondrial activation and insulin secretion in pancreatic beta cells.
Q33207008Hydrostatic pressure induces apoptosis in the human leukaemic T-cell line Jurkat via the mitochondrial pathway
Q44046764Hypoglossal motor neurons display a reduced calcium increase after axotomy in mice with upregulated parvalbumin
Q44602920Hypothalamic vasopressin release and hepatocyte Ca 2+ signaling during liver regeneration: an interplay stimulating liver growth and bile flow
Q39140608IP3 receptor mutations and brain diseases in human and rodents.
Q28202808IRBIT, a novel inositol 1,4,5-trisphosphate (IP3) receptor-binding protein, is released from the IP3 receptor upon IP3 binding to the receptor
Q33839155Identification and dissection of Ca(2+)-binding sites in the extracellular domain of Ca(2+)-sensing receptor
Q36627602Identification of Lys49-PLA2 from crude venom of Crotalus atrox as a human neutrophil-calcium modulating protein
Q34065260Identification of a family of calcium sensors as protein ligands of inositol trisphosphate receptor Ca(2+) release channels
Q28117761Identification of a novel loss-of-function calcium channel gene mutation in short QT syndrome (SQTS6)
Q45735381Identification of human cancer-related genes by naturally occurring Hepatitis B Virus DNA tagging
Q47239181Identification of weight-bearing-responsive elements in the skeletal muscle sarco(endo)plasmic reticulum Ca2+ ATPase (SERCA1) gene
Q30477207Imaging cellular signals in the heart in vivo: Cardiac expression of the high-signal Ca2+ indicator GCaMP2.
Q33848906Imaging intraorganellar Ca2+ at subcellular resolution using CEPIA
Q24673906Imaging single-channel calcium microdomains
Q36210548Immunohistochemical and calcium imaging methods in wholemount rat retina
Q41700451Impaired NFATc translocation and failure of Th2 development in Itk-deficient CD4+ T cells
Q39063410Implications of oxidative stress on viral pathogenesis
Q90315788Improvement of signal-to-noise ratio in parallel neuron arrays with spatially nearest neighbor correlated noise
Q45932228In vitro effects of environmentally relevant polybrominated diphenyl ether (PBDE) congeners on calcium buffering mechanisms in rat brain.
Q39992262In vitro evaluation of casein phosphopeptide-amorphous calcium phosphate as a potential tooth transport medium: viability and apoptosis in L929 fibroblasts
Q90485522In vitro human stem cell derived cultures to monitor calcium signaling in neuronal development and function
Q39521453In vivo imaging of near-membrane calcium ions with two-photon probes
Q30899955In vivo spectrometric calcium flux recordings of intrinsic Caudate-Putamen cells and transplanted IMR-32 neuroblastoma cells using miniature fiber optrodes in anesthetized and awake rats and monkeys
Q74127924Incorporation of N-propanoylneuraminic acid leads to calcium oscillations in oligodendrocytes upon the application of GABA
Q24812245Incorporation of branched-chain fatty acid into cellular lipids and caspase-independent apoptosis in human breast cancer cell line, SKBR-3.
Q40609771Increased calcium influx and ribosomal content correlate with resistance to endoplasmic reticulum stress-induced cell death in mutant leukemia cell lines
Q47594568Increased intracellular Ca2+ concentrations prevent membrane localization of PH domains through the formation of Ca2+-phosphoinositides.
Q24683719Increased islet apoptosis in Pdx1+/- mice
Q30786246Increasing hydroxyapatite incorporation into poly(methylmethacrylate) cement increases osteoblast adhesion and response.
Q44049940Inducible nitric-oxide synthase attenuates vasopressin-dependent Ca2+ signaling in rat hepatocytes.
Q42210513Inflammatory activation of human cardiac fibroblasts leads to altered calcium signaling, decreased connexin 43 expression and increased glutamate secretion
Q37960605Influence of calcium and other cations on surface adhesion of bacteria and diatoms: A review
Q31148501Information transfer in signaling pathways: a study using coupled simulated and experimental data
Q56984168Inhibition of Autophagy by Captopril Attenuates Prion Peptide-Mediated Neuronal Apoptosis via AMPK Activation
Q44086578Inhibition of SERCA Ca2+ pumps by 2-aminoethoxydiphenyl borate (2-APB). 2-APB reduces both Ca2+ binding and phosphoryl transfer from ATP, by interfering with the pathway leading to the Ca2+-binding sites
Q28204580Inhibition of human SERCA3 by PL/IM430. Molecular analysis of the interaction
Q28183525Inhibition of store-operated calcium entry contributes to the anti-proliferative effect of non-steroidal anti-inflammatory drugs in human colon cancer cells
Q44130943Inhibition of the type 1 inositol 1,4,5-trisphosphate receptor by 2-aminoethoxydiphenylborate
Q48892405Injection of sperm cytosolic factor into mouse metaphase II oocytes induces different developmental fates according to the frequency of [Ca(2+)](i) oscillations and oocyte age.
Q28575960Inositol 1,4,5-trisphosphate receptor localization and stability in neonatal cardiomyocytes requires interaction with ankyrin-B
Q44896476Inositol 1,4,5-trisphosphate receptor regulates replication, differentiation, infectivity and virulence of the parasitic protist Trypanosoma cruzi
Q49666213Inositol 1,4,5-trisphosphate receptors and neurodegenerative disorders
Q33934302Inositol signaling and plant growth.
Q33946097Inositol trisphosphate receptor Ca2+ release channels in neurological diseases
Q33983069Inositol trisphosphate receptor Ca2+ release channels.
Q38885850Inseparable tandem: evolution chooses ATP and Ca2+ to control life, death and cellular signalling
Q34810222Insights into modulation of calcium signaling by magnesium in calmodulin, troponin C and related EF-hand proteins
Q24599847Integration of calcineurin and MEF2 signals by the coactivator p300 during T-cell apoptosis
Q48597501Intercellular Communication Via Intracellular Calcium Oscillations
Q51983531Intercellular calcium signalling in cultured renal epithelia: a theoretical study of synchronization mode and pacemaker activity.
Q51198112Intercellular waves propagation in an array of cells coupled through paracrine signaling: a computer simulation study.
Q44988728Internal stochastic resonance under two-parameter modulation in intercellular calcium ion oscillations
Q33533346Intra-cluster percolation of calcium signals
Q44538744Intracellular Ca2+ homeostatic regulation and 4-hydroxynonenal-induced aortic endothelial dysfunction
Q38168374Intracellular calcium channels: inositol-1,4,5-trisphosphate receptors
Q48336810Intracellular calcium oscillations in strongly metastatic human breast and prostate cancer cells: control by voltage-gated sodium channel activity.
Q44000528Intracellular calcium oscillations signal apoptosis rather than activation in in vitro aged mouse eggs
Q37398591Intracellular calcium plays a critical role in the alcohol-mediated death of cerebellar granule neurons
Q35837754Intracellular calcium signals and control of cell proliferation: how many mechanisms?
Q42055478Intracellular calcium signals display an avalanche-like behavior over multiple lengthscales.
Q44050259Intracellular calcium stores regulate activity-dependent neuropeptide release from dendrites
Q30499524Intracellular delivery of bioactive molecules using light-addressable nanocapsules
Q51788938Introduction to focus issue: intracellular Ca2+ dynamics--a change of modeling paradigm?
Q43269168Investigating the effects of molecular crowding on Ca2+ diffusion using a particle-based simulation model
Q43593280Investigation of the ternary D-myo-inositol 1,2,6-tris(phosphate)-spermine-Zn2+ system in solution
Q54025967Involvement of c-Fos in signaling grp78 induction following ER calcium release.
Q33871158Involvement of gap junctional communication in myogenesis
Q41838197Involvement of phosphoinositide 3-kinase and PTEN protein in mechanism of activation of TRPC6 protein in vascular smooth muscle cells
Q64084189Ion Channels: New Actors Playing in Chemotherapeutic Resistance
Q36345954Ion channels and cancer
Q38184990Ion channels in cancer: future perspectives and clinical potential
Q36345950Ion channels in cell proliferation and apoptotic cell death
Q35965652Ion channels in osteoblasts: a story of two intracellular organelles
Q38811371Ion channels in regulated cell death
Q34127634Ionomycin-activated calpain triggers apoptosis. A probable role for Bcl-2 family members.
Q28571963Ischemia enhances activation by Ca2+ and redox modification of ryanodine receptor channels from rat brain cortex
Q51404715Ischemia-induced inhibition of active calcium transport into gerbil brain microsomes: effect of anesthetics and models of ischemia.
Q39225781Isolation and characterization of the 5´-upstream region of the human voltage-gated Ca(2+) channel α 2δ-1 auxiliary subunit gene: promoter analysis and regulation by transcription factor Sp1.
Q59903436Jensen’s inequality as a tool for explaining the effect of oscillations on the average cytosolic calcium concentration
Q38018945K(Ca)2 and k(ca)3 channels in learning and memory processes, and neurodegeneration.
Q39998605KCNA1 and TRPC6 ion channels and NHE1 exchanger operate the biological outcome of HGF/scatter factor in renal tubular cells
Q24538918Kaposi's sarcoma-associated herpesvirus mitochondrial K7 protein targets a cellular calcium-modulating cyclophilin ligand to modulate intracellular calcium concentration and inhibit apoptosis
Q46608561Keratinocytes cultured from patients with Hailey-Hailey disease and Darier disease display distinct patterns of calcium regulation.
Q38107681Key role of lipids in heat stress management.
Q30373952L-type Calcium Channel Cav1.2 Is Required for Maintenance of Auditory Brainstem Nuclei.
Q44005252LAT displacement from lipid rafts as a molecular mechanism for the inhibition of T cell signaling by polyunsaturated fatty acids
Q47303939LEFTY2 inhibits endometrial receptivity by downregulating Orai1 expression and store-operated Ca2+ entry
Q28216181LTRPC2 Ca2+-permeable channel activated by changes in redox status confers susceptibility to cell death
Q33378365Lack of association between the CALM1 core promoter polymorphism (-16C/T) and susceptibility to knee osteoarthritis in a Chinese Han population
Q35247759Late-onset inner retinal dysfunction in mice lacking sigma receptor 1 (σR1).
Q38311662Ligand binding directly stimulates ubiquitination of the inositol 1, 4,5-trisphosphate receptor
Q34833218Linkage of beta1-adrenergic stimulation to apoptotic heart cell death through protein kinase A-independent activation of Ca2+/calmodulin kinase II.
Q83861879Linking microstructure and nanochemistry in human dental tissues
Q46048211Listeriolysin O affects barrier function and induces chloride secretion in HT-29/B6 colon epithelial cells
Q30908047Live cell imaging using confocal microscopy induces intracellular calcium transients and cell death.
Q44270187Local and global spontaneous calcium events regulate neurite outgrowth and onset of GABAergic phenotype during neural precursor differentiation.
Q35885033Long-Lasting Sparks: Multi-Metastability and Release Competition in the Calcium Release Unit Network
Q44506961Low energy visible light induces reactive oxygen species generation and stimulates an increase of intracellular calcium concentration in cardiac cells
Q58799585MPP decreases store-operated calcium entry and TRPC1 expression in Mesenchymal Stem Cell derived dopaminergic neurons
Q37176146Management of non-neuronopathic Gaucher disease with special reference to pregnancy, splenectomy, bisphosphonate therapy, use of biomarkers and bone disease monitoring
Q34114394Maturation of channels and receptors: consequences for excitability
Q33867783Mechanically induced intracellular calcium waves in osteoblasts demonstrate calcium fingerprints in bone cell mechanotransduction
Q44306042Mechanism of melatonin-induced oscillations in the peroxidase-oxidase reaction
Q44489234Mechanism of protection of peroxidase activity by oscillatory dynamics
Q46806940Mechanism of suppression of physiological functions in hypothermia and means for their stimulation without body warming
Q48647754Mechanisms of TiO2 nanoparticle-induced neuronal apoptosis in rat primary cultured hippocampal neurons
Q28571331Mechanisms of prolonged presynaptic Ca2+ signaling and glutamate release induced by TRPV1 activation in rat sensory neurons
Q40465067Mechanistic and functional changes in Ca2+ entry after retinoic acid-induced differentiation of neuroblastoma cells.
Q84113307Metabotropic glutamate receptors regulate hippocampal CA1 pyramidal neuron excitability via Ca²⁺ wave-dependent activation of SK and TRPC channels
Q33948972Metal ion cooperativity in ribozyme cleavage of RNA.
Q34378429Methylation and colorectal cancer
Q35577699Mice lacking functional TRPV1 are protected from pressure overload cardiac hypertrophy
Q34014024Microcin E492, a channel-forming bacteriocin from Klebsiella pneumoniae, induces apoptosis in some human cell lines
Q52537936Microscopic properties of elementary Ca2+ release sites in non-excitable cells.
Q100512497Minimal contribution of IP3R2 in cardiac differentiation and derived ventricular-like myocytes from human embryonic stem cells
Q52575434Minimal domain requirement for cation transport by the potassium-dependent Na/Ca-K exchanger. Comparison with an NCKX paralog from Caenorhabditis elegans.
Q52041668Minimal model for complex dynamics in cellular processes.
Q40805115Mitochondria recycle Ca(2+) to the endoplasmic reticulum and prevent the depletion of neighboring endoplasmic reticulum regions
Q41596964Mitochondrial characteristics in oocytes of the domestic cat (Felis catus) after in vitro maturation and vitrification.
Q35751689Mitochondrial distribution and microtubule organization in fertilized and cloned porcine embryos: implications for developmental potential.
Q27027384Mitochondrial signaling: forwards, backwards, and in between
Q35739853Mitochondrial signaling: the retrograde response
Q34549893Modelling of simple and complex calcium oscillations. From single-cell responses to intercellular signalling.
Q36649473Modifying effect of calcium/magnesium intake ratio and mortality: a population-based cohort study
Q38038228Modulating macroautophagy: a neuronal perspective
Q52536986Modulation of mitochondrial Ca(2+) homeostasis by Bcl-2.
Q42071980Modulation of neurological deficits and expression of glutamate receptors during experimental autoimmune encephalomyelitis after treatment with selected antagonists of glutamate receptors
Q28344311Modulation of type-1 Ins(1,4,5)P3 receptor channels by the FK506-binding protein, FKBP12
Q36832884Molecular "negativity" may underlie multiple sclerosis: role of the myelin basic protein family in the pathogenesis of MS.
Q38042081Molecular aspects of vitamin D anticancer activity
Q55052477Molecular biology of rotavirus entry and replication.
Q35150622Molecular characteristics, mRNA expression, and alternative splicing of a ryanodine receptor gene in the oriental fruit fly, Bactrocera dorsalis (Hendel).
Q28587761Molecular cloning and characterization of CLICK-III/CaMKIgamma, a novel membrane-anchored neuronal Ca2+/calmodulin-dependent protein kinase (CaMK)
Q39026971Morphogenetic study on the maturation of osteoblastic cell as induced by inorganic polyphosphate
Q40840020Morphological changes in the nucleus and actin cytoskeleton in the process of Fas-induced apoptosis in Jurkat T cells
Q28363682Mouse mast cell secretory granules can function as intracellular ionic oscillators
Q48029020Multiple calcium binding sites make calmodulin multifunctional.
Q50135945Multiple calcium patterns of rat osteoblasts under fluidic shear stress
Q41504880Multiple cellular roles of Neurospora crassa plc-1, splA2, and cpe-1 in regulation of cytosolic free calcium, carotenoid accumulation, stress responses, and acquisition of thermotolerance
Q28210479Multiplicity of mechanisms of serotonin receptor signal transduction
Q28576465Muscarinic acetylcholine receptor regulation of TRP6 Ca2+ channel isoforms. Molecular structures and functional characterization
Q22009038Mutations in ATP2A2, encoding a Ca2+ pump, cause Darier disease
Q24297807MxA, a member of the dynamin superfamily, interacts with the ankyrin-like repeat domain of TRPC
Q92641372NAADP Receptors
Q34147867NAADP receptors
Q24631606NAIP interacts with hippocalcin and protects neurons against calcium-induced cell death through caspase-3-dependent and -independent pathways
Q40814092NF-kappaB activation and susceptibility to apoptosis after polyamine depletion in intestinal epithelial cells
Q39804742NFAT functions as a working memory of Ca2+ signals in decoding Ca2+ oscillation
Q28216151NFAT signaling: choreographing the social lives of cells
Q36526298NMR and molecular dynamics studies of the interaction of melatonin with calmodulin
Q37561380Nanosecond Pulsed Electric Fields Enhance the Anti-tumour Effects of the mTOR Inhibitor Everolimus against Melanoma
Q37959319Nanospaces between endoplasmic reticulum and mitochondria as control centres of pancreatic β-cell metabolism and survival.
Q50462433Near-IR-triggered, remote-controlled release of metal ions: a novel strategy for caged ions.
Q89988051Near-Infrared Light Triggered-Release in Deep Brain Regions Using Ultra-photosensitive Nanovesicles
Q33733240Neuromuscular disease and calcium channels
Q39094786Neuronal Ryanodine Receptors in Development and Aging
Q36934762Neuronal calcium mishandling and the pathogenesis of Alzheimer's disease
Q35051305Neuronal survival in the balance: are endoplasmic reticulum membrane proteins the fulcrum?
Q48057138Neurospora crassa homologue of Neuronal Calcium Sensor-1 has a role in growth, calcium stress tolerance, and ultraviolet survival
Q35710568Neurotoxicity by synthetic androgen steroids: oxidative stress, apoptosis, and neuropathology: A review.
Q47812978New Aspects of the Contribution of ER to SOCE Regulation: TRPC Proteins as a Link Between Plasma Membrane Ion Transport and Intracellular Ca2+ Stores
Q43002260Nicotinic acid-adenine dinucleotide phosphate activates the skeletal muscle ryanodine receptor
Q51129304Nitric oxide activates TRP channels by cysteine S-nitrosylation.
Q34727863Non-genomic actions of androgens.
Q34245774Nonlinear and Stochastic Dynamics in the Heart
Q53287298Normalizing effect of plant-originated glycoprotein (116 kDa) on G0/G1 arrest in cadmium chloride-induced primary cultured mouse myelocytes
Q24532234Novel CIPK1-associated proteins in Arabidopsis contain an evolutionarily conserved C-terminal region that mediates nuclear localization
Q39581519Novel evidence that testosterone promotes cell proliferation and differentiation via G protein-coupled receptors in the rat L6 skeletal muscle myoblast cell line
Q40216257Novel functions of small conductance Ca2+-activated K+ channel in enhanced cell proliferation by ATP in brain endothelial cells
Q27303144Novel quinazolinone MJ-29 triggers endoplasmic reticulum stress and intrinsic apoptosis in murine leukemia WEHI-3 cells and inhibits leukemic mice
Q36227308Novel sarco(endo)plasmic reticulum proteins and calcium homeostasis in striated muscles.
Q37316618Nuclear calcium signaling: a cell within a cell
Q90950278Nuclear calcium signatures are associated with root development
Q42813142Observable effects of Ca2+ buffers on local Ca2+ signals
Q47350563On the fate of skeletal myoblasts in a cardiac environment: down-regulation of voltage-gated ion channels
Q40225975On the role of stochastic channel behavior in intracellular Ca2+ dynamics
Q58426379Oncogenic KRAS suppresses store-operated Ca 2+ entry and I CRAC through ERK pathway-dependent remodelling of STIM expression in colorectal cancer cell lines
Q42513050Oncosis and apoptosis induction by activation of an overexpressed ion channel in breast cancer cells
Q39095462Optogenetic toolkit for precise control of calcium signaling
Q89731179Orai, STIM, and PMCA contribute to reduced calcium signal generation in CD8+ T cells of elderly mice
Q44254818Orai1 mediates store-operated Ca2+ entry during fertilization in mammalian oocytes
Q50093685Orai3 calcium channel and resistance to chemotherapy in breast cancer cells: the p53 connection.
Q58769634Organelle Optogenetics: Direct Manipulation of Intracellular Ca Dynamics by Light
Q21144219Orientation of the calcium channel beta relative to the alpha(1)2.2 subunit is critical for its regulation of channel activity
Q78673368Osteoblastic cells have refractory periods for fluid-flow-induced intracellular calcium oscillations for short bouts of flow and display multiple low-magnitude oscillations during long-term flow
Q33949448Ouabain, a steroid hormone that signals with slow calcium oscillations.
Q34620989Our "energy-Ca(2+) signaling deficits" hypothesis and its explanatory potential for key features of Alzheimer's disease
Q34110103Overexpression of an alpha 1H (Cav3.2) T-type calcium channel during neuroendocrine differentiation of human prostate cancer cells.
Q40743401Overexpression of calreticulin modulates protein kinase B/Akt signaling to promote apoptosis during cardiac differentiation of cardiomyoblast H9c2 cells
Q40542753Oxidative stress-induced apoptosis in retinal photoreceptor cells is mediated by calpains and caspases and blocked by the oxygen radical scavenger CR-6.
Q42218702Pharmacological Characterization of the Mechanisms Involved in Delayed Calcium Deregulation in SH-SY5Y Cells Challenged with Methadone
Q37910243Pharmacologists and Alzheimer disease therapy: to boldly go where no scientist has gone before.
Q42908525Phosphatidic acid domains in membranes: effect of divalent counterions.
Q46217447Phosphatidylinositol (4,5)bisphosphate inhibits K+-efflux channel activity in NT1 tobacco cultured cells
Q39305479Phospholipase A2 activity-dependent stimulation of Ca2+ entry by human parvovirus B19 capsid protein VP1
Q28574874Phospholipase C-gamma is required for agonist-induced Ca2+ entry
Q47923584Phospholipase C-mediated calcium signalling is required for fungal development and pathogenicity in Magnaporthe oryzae.
Q41558346Phospholipid Phosphatase 4 promotes proliferation and tumorigenesis, and activates Ca2+-permeable Cationic Channel in lung carcinoma cells
Q30515041Photochemically initiated intracellular astrocytic calcium waves in living mice using two-photon uncaging of IP(3).
Q73955162Physiological blocking of the mechanisms of cold death: theoretical and experimental considerations
Q39675062Physiological levels of TNFalpha stimulation induce stochastic dynamics of NF-kappaB responses in single living cells
Q30497665Pituitary growth hormone network responses are sexually dimorphic and regulated by gonadal steroids in adulthood
Q34878884Plasma membrane Ca-ATPases in the nervous system during development and ageing
Q34578858Plasma membrane Ca2+ ATPases as dynamic regulators of cellular calcium handling
Q24290994Plasma membrane Ca2+-atpase isoforms 2b and 4b interact promiscuously and selectively with members of the membrane-associated guanylate kinase family of PDZ (PSD95/Dlg/ZO-1) domain-containing proteins
Q53271781Plasma membrane calcium ATPase expression in human colon multistep carcinogenesis.
Q36979457Plasma-membrane Ca(2+) pumps: structural diversity as the basis for functional versatility
Q28211116Plasticity of KIR channels in human smooth muscle cells from internal thoracic artery
Q40710847Polyamines regulate beta-catenin tyrosine phosphorylation via Ca(2+) during intestinal epithelial cell migration
Q24292332Polycystin-2 is an intracellular calcium release channel
Q39254065Post-translational modification plays an essential role in the translocation of annexin A1 from the cytoplasm to the cell surface.
Q28346072Predetermined recruitment of calcium release sites underlies excitation-contraction coupling in rat atrial myocytes
Q41557386Predicting Ca2+ -binding sites using refined carbon clusters
Q35156329Prediction and analysis of canonical EF hand loop and qualitative estimation of Ca²⁺ binding affinity
Q58769494Preferential Binding of Mg Over Ca to CIB2 Triggers an Allosteric Switch Impaired in Usher Syndrome Type 1J
Q92588155Preserved Calretinin Interneurons in an App Model of Alzheimer's Disease Disrupt Hippocampal Inhibition via Upregulated P2Y1 Purinoreceptors
Q97524455Prion peptide-mediated calcium level alteration governs neuronal cell damage through AMPK-autophagy flux
Q36718674Promoter-Specific Effects of DREADD Modulation on Hippocampal Synaptic Plasticity and Memory Formation.
Q28345086Propagation of the apoptotic signal by mitochondrial waves
Q45295696Prostaglandin E2 EP1 receptor antagonist improves motor deficits and rescues memory decline in R6/1 mouse model of Huntington's disease
Q35201401Protective effect of calpain inhibitor N-acetyl-L-leucyl-L-leucyl-L-norleucinal on acute alcohol consumption related cardiomyopathy
Q78145390Protective effect of low frequency low energy pulsing electromagnetic fields on acute experimental myocardial infarcts in rats
Q33834084Protein folding and deficiencies caused by dominant-negative mutants of hormones
Q27003283Protein homeostasis as a therapeutic target for diseases of protein conformation
Q60949363Proteomic Profile of Carbonylated Proteins Screen Regulation of Apoptosis via CaMK Signaling in Response to Regular Aerobic Exercise
Q43060249Puff-wave transition in an inhomogeneous model for calcium signals
Q39972019Quantifying stochastic effects in biochemical reaction networks using partitioned leaping.
Q33855347RAFTK/Pyk2-mediated cellular signalling
Q39761712RANKL-mediated reactive oxygen species pathway that induces long lasting Ca2+ oscillations essential for osteoclastogenesis
Q34166301RET PLCγ phosphotyrosine binding domain regulates Ca2+ signaling and neocortical neuronal migration.
Q24630254RTX proteins: a highly diverse family secreted by a common mechanism
Q36993488Rapid actions of androgens
Q37371423Rat vas deferens SERCA2 is modulated by Ca2+/calmodulin protein kinase II-mediated phosphorylation.
Q57208132Ratiometric analysis of calcium mobilization
Q37058615Rational Design of Particle Mesh Ewald Compatible Lennard-Jones Parameters for +2 Metal Cations in Explicit Solvent
Q78047083Re: Ellmerer et al. (1998) Biosensors & Bioelectronics 13: 1007-1013
Q30541066Reaction-diffusion systems in intracellular molecular transport and control
Q46841918Reactive oxygen species and Udx1 during early sea urchin development
Q56838103Reading the patterns in living cells —the physics of ca2+signaling
Q27317892Real-Time Dynamics of Ca2+, Caspase-3/7, and Morphological Changes in Retinal Ganglion Cell Apoptosis under Elevated Pressure
Q44425153Receptor-coupled, DAG-gated Ca2+-permeable cationic channels in LNCaP human prostate cancer epithelial cells.
Q40938019Receptors linked to polyphosphoinositide hydrolysis stimulate Ca2+ extrusion by a phospholipase C-independent mechanism.
Q33958516Reciprocal communication systems between astrocytes and neurones
Q35805009Reciprocal regulation and integration of signaling by intracellular calcium and cyclic GMP.
Q41607105Recovery of mitochondrial function and endogenous antioxidant systems in vitrified bovine oocytes during extended in vitro culture
Q59128094Reduced Cytosolic Calcium as an Early Decisive Cellular State in Parkinson's Disease and Synucleinopathies
Q34718076Regulation and function of Cav3.1 T-type calcium channels in IGF-I-stimulated pulmonary artery smooth muscle cells.
Q33950353Regulation of Ca2+ channel expression at the cell surface by the small G-protein kir/Gem
Q36124945Regulation of Cdc2/cyclin B activation in Xenopus egg extracts via inhibitory phosphorylation of Cdc25C phosphatase by Ca(2+)/calmodulin-dependent protein [corrected] kinase II.
Q38810445Regulation of breast tumorigenesis through acid sensors.
Q48490680Regulation of inositol 1,4,5-triphosphate receptor, type 1 (IP3R1) in hypoxic/reperfusion injury of white matter
Q28139129Regulation of intracellular calcium by a signalling complex of IRAG, IP3 receptor and cGMP kinase Ibeta
Q36228270Regulation of peripheral T cell activation by calreticulin
Q43509775Regulation of phosphatidylserine transbilayer redistribution by store-operated Ca2+ entry: role of actin cytoskeleton
Q53922264Regulation of ryanodine receptor opening by lumenal Ca(2+) underlies quantal Ca(2+) release in PC12 cells.
Q36624167Regulation of ryanodine receptors from skeletal and cardiac muscle during rest and excitation
Q73819740Regulation of secretory protein gene expression in paramecium role of the cortical exocytotic sites
Q92567538Regulation of signal transduction in Coilia nasus during migration
Q37225373Regulation of store-operated and voltage-operated Ca2+ channels in the proliferation and death of oligodendrocyte precursor cells by golli proteins
Q39501406Relationship between intracellular Ca²⁺ and ROS during fluoride-induced injury in SH-SY5Y cells
Q40280198Release currents of IP(3) receptor channel clusters and concentration profiles
Q34688803Remodeling the proteostasis network to rescue glucocerebrosidase variants by inhibiting ER-associated degradation and enhancing ER folding
Q37566460Remodelling of Ca2+ transport in cancer: how it contributes to cancer hallmarks?
Q27334512Rescuing loading induced bone formation at senescence
Q51075320Residue-residue interactions regulating the Ca2+-induced EF-hand conformation changes in calmodulin.
Q59904754Resonance effects determine the frequency of bursting Ca2+ oscillations
Q73822570Responses to reversible anoxia of intracellular free and bound Ca(2+) in rat cortical slices
Q57092203Resveratrol promotes the embryonic development of vitrified mouse oocytes after in vitro fertilization
Q37952272Review--Interactions between diatoms and stainless steel: focus on biofouling and biocorrosion
Q52105621Rhizobium-Induced Calcium Spiking in Lotus japonicus
Q37972068Road to Alzheimer's disease: the pathomechanism underlying
Q46897963Role of ATP in DNA synthesis of renal proximal tubule cells: involvement of calcium, MAPKs, and CDKs
Q46761892Role of NHE1 in calcium signaling and cell proliferation in human CNS pericytes
Q44312311Role of TRPM2 cation channels in dorsal root ganglion of rats after experimental spinal cord injury
Q40379206Role of calreticulin in the sensitivity of myocardiac H9c2 cells to oxidative stress caused by hydrogen peroxide
Q44437646Role of group I metabotropic glutamate receptors and NMDA receptors in homocysteine-evoked acute neurodegeneration of cultured cerebellar granule neurones
Q93014408Role of intracellular Ca2+-based mechanotransduction of human periodontal ligament fibroblasts
Q38826623Role of phosphatase and tensin homolog in hypoxic pulmonary vasoconstriction
Q24652395Role of sigma-1 receptor C-terminal segment in inositol 1,4,5-trisphosphate receptor activation: constitutive enhancement of calcium signaling in MCF-7 tumor cells
Q40209033Role of the lipopolysaccharide-CD14 complex for the activity of hemolysin from uropathogenic Escherichia coli
Q28192707Role of the nitric oxide/cyclic GMP/Ca2+ signaling pathway in the pyrogenic effect of interleukin-1beta
Q46567241Roles of external noise correlation in optimal intracellular calcium signaling
Q33961958Ruled by waves? Intracellular and intercellular calcium signalling
Q44395860Ruthenium red, inhibitor of mitochondrial Ca2+ uniporter, inhibits curcumin-induced apoptosis via the prevention of intracellular Ca2+ depletion and cytochrome c release
Q38217975Ryanodine receptors: physiological function and deregulation in Alzheimer disease.
Q24291323SERCA1 truncated proteins unable to pump calcium reduce the endoplasmic reticulum calcium concentration and induce apoptosis
Q55717680STIM1 Knockout Enhances PDGF-Mediated Ca2+ Signaling through Upregulation of the PDGFR⁻PLCγ⁻STIM2 Cascade.
Q35932914STIM1 accelerates cell senescence in a remodeled microenvironment but enhances the epithelial-to-mesenchymal transition in prostate cancer
Q34183867Saltatory and continuous calcium waves and the rapid buffering approximation
Q30475365Saving cells from ultrasound-induced apoptosis: quantification of cell death and uptake following sonication and effects of targeted calcium chelation
Q37076175Secretory mechanisms and Ca2+ signaling in gametes: similarities to regulated neuroendocrine secretion in somatic cells and involvement in emerging pathologies
Q33744641Selected tetrapeptides lead to a GLP-1 release from the human enteroendocrine cell line NCI-H716
Q44399466Selection of intracellular calcium patterns in a model with clusteredCa2+release channels
Q51962591Selective regulation of cellular processes via protein cascades acting as band-pass filters for time-limited oscillations.
Q36321026Selective role for superoxide in InsP3 receptor-mediated mitochondrial dysfunction and endothelial apoptosis
Q44523918Sensitivity and flexibility of regular and chaotic calcium oscillations
Q48079057Serum 25-hydroxyvitamin D is associated with reduced verbal episodic memory in healthy, middle-aged and older adults
Q40756960Serum deprivation increases ceramide levels and induces apoptosis in undifferentiated HN9.10e cells
Q33730425Shaping excitation at glutamatergic synapses
Q50681312Sheet excitability and nonlinear wave propagation.
Q33166770Short QT Syndrome - Review of Diagnosis and Treatment
Q34435917Sigma receptors and iboga alkaloids
Q44795611Signal mass and Ca²⁺ kinetics in local calcium events: a modeling study.
Q40282733Signaling pathways involved with the stimulatory effect of angiotensin II on vacuolar H+-ATPase in proximal tubule cells
Q24305341Similar Ca(2+)-signaling properties in keratinocytes and in COS-1 cells overexpressing the secretory-pathway Ca(2+)-ATPase SPCA1
Q74224996Similar effects of ether phospholipids, PAF and lyso-PAF on the Ca(2+)-ATPase activity of rat brain synaptosomes and leukocyte membranes
Q31054077Simple data-driven models of intracellular calcium dynamics with predictive power
Q46254318Simplified model of cytosolic Ca2+ dynamics in the presence of one or several clusters of Ca2+ -release channels
Q50581120Simulation of intracellular Ca²⁺ transients in osteoblasts induced by fluid shear stress and its application.
Q44290653Simulation of waves in calcium models with 3D spherical geometry
Q51004815Simulations of intracellular calcium release dynamics in response to a high-intensity, ultrashort electric pulse.
Q30361439Singing modulates parvalbumin interneurons throughout songbird forebrain vocal control circuitry
Q60660320Slow time evolution of two-time-scale reaction-diffusion systems: The physical origin of nondiffusive transport
Q33995433Sodium/calcium exchangers selectively regulate calcium signaling in mouse taste receptor cells.
Q42107446Solution structure and backbone dynamics of Calsensin, an invertebrate neuronal calcium-binding protein
Q44300140Spatial profiles of store-dependent calcium release in motoneurones of the nucleus hypoglossus from newborn mouse
Q39971841Spatiotemporal characteristics of calcium dynamics in astrocytes
Q34049067Spatiotemporal dynamics of intracellular calcium in the middle cerebral artery isolated from stroke-prone spontaneously hypertensive rats
Q44768427Specific structural requirements for the inhibitory effect of thapsigargin on the Ca2+ ATPase SERCA.
Q33728912Specificity of calcium/calmodulin-dependent protein kinases in mouse egg activation
Q41089465Spectrally tunable uncaging of biological stimuli from nanocapsules
Q33784652Sphingosine kinase regulates oxidized low density lipoprotein-mediated calcium oscillations and macrophage survival
Q73963563Squamous cell tumors in mice heterozygous for a null allele of Atp2a2, encoding the sarco(endo)plasmic reticulum Ca2+-ATPase isoform 2 Ca2+ pump
Q42458729Stimulation of capacitative calcium entry in HL-60 cells by nanosecond pulsed electric fields
Q42758107Stochastic fire-diffuse-fire model with realistic cluster dynamics.
Q51824773Stochastic resonance is a method to improve the biosynthetic response of chondrocytes to mechanical stimulation.
Q74176749Store depletion and store-operated Ca2+ current in human prostate cancer LNCaP cells: involvement in apoptosis
Q44400229Store operated Ca2+ influx by selective depletion of ryanodine sensitive Ca2+ pools in primary human skeletal muscle cells
Q40645346Store-operated Ca2+ channels in prostate cancer epithelial cells: function, regulation, and role in carcinogenesis.
Q40929782Store-operated Ca2+ entry: evidence for a secretion-like coupling model
Q30596771Strength of Ca(2+) binding to retinal lipid membranes: consequences for lipid organization
Q43956364Structural analysis, identification, and design of calcium-binding sites in proteins
Q27680764Structural basis for a hand-like site in the calcium sensor CatchER with fast kinetics
Q44253409Study of the protective effect of calcium channel blockers against neuronal damage induced by glutamate in cultured hippocampal neurons.
Q47100285Study on the role of transient receptor potential C6 channels in esophageal squamous cell carcinoma radiosensitivity
Q36371619Subcellular distribution of calcium during spermatogenesis of zebrafish, Danio rerio.
Q39629842Substance P immunoreactive nerve fibres are related to gastric cancer differentiation status and could promote proliferation and migration of gastric cancer cells
Q35703292Suppression of Propionibacterium acnes Infection and the Associated Inflammatory Response by the Antimicrobial Peptide P5 in Mice
Q34671790Surface dynamics in allosteric regulation of protein-protein interactions: modulation of calmodulin functions by Ca2+.
Q38683359Surface sensing and stress-signalling in Ulva and fouling diatoms - potential targets for antifouling: a review
Q40142082Sustained elevation of intracellular cGMP causes oxidative stress triggering calpain-mediated apoptosis in photoreceptor degeneration
Q28139783Sustained recruitment of phospholipase C-gamma to Gab1 is required for HGF-induced branching tubulogenesis
Q40169510Switching from simple to complex oscillations in calcium signaling
Q37570537Synaptic homeostasis and input selectivity follow from a calcium-dependent plasticity model
Q33699195Synthesis and characterization of cell-permeant 6-nitrodibenzofuranyl-caged IP3.
Q38841376Synthesis of new indole-based bisphosphonates and evaluation of their chelating ability in PE/CA-PJ15 cells
Q44046161T-Type calcium channel alpha1G and alpha1H subunits in human retinoblastoma cells and their loss after differentiation
Q37217714T-type Ca2+ channel expression in human esophageal carcinomas: a functional role in proliferation
Q35645713T-type calcium channel antagonists, mibefradil and NNC-55-0396 inhibit cell proliferation and induce cell apoptosis in leukemia cell lines
Q36691003TLR3-/4-Priming Differentially Promotes Ca(2+) Signaling and Cytokine Expression and Ca(2+)-Dependently Augments Cytokine Release in hMSCs
Q33757601TRPC channels and their implication in neurological diseases
Q88035861TRPC1 Deficiency Impairs the Endothelial Progenitor Cell Function via Inhibition of Calmodulin/eNOS Pathway
Q57456309TRPV2-induced Ca-calcineurin-NFAT signaling regulates differentiation of osteoclast in multiple myeloma
Q48061178TRPV4 mediates the Ca2+ influx required for the interaction between flightless-1 and non-muscle myosin, and collagen remodeling
Q37649459Taking into Account the Ion-induced Dipole Interaction in the Nonbonded Model of Ions
Q37341230Targeting Bcl-2 based on the interaction of its BH4 domain with the inositol 1,4,5-trisphosphate receptor.
Q44412390Temporal variations in protein tyrosine kinase activity in leukaemic cells: response to all-trans retinoic acid
Q33680652The AT2 receptor: fact, fancy and fantasy
Q44628577The Allosteric Potentiation of Nicotinic Acetylcholine Receptors by Galantamine Is Transduced into Cellular Responses in Neurons: Ca2+Signals and Neurotransmitter Release
Q37690637The Function of the Mitochondrial Calcium Uniporter in Neurodegenerative Disorders.
Q31780083The Golgi PMR1 P-type ATPase of Caenorhabditis elegans. Identification of the gene and demonstration of calcium and manganese transport
Q47582963The Role of Sigma 1 Receptor as a Neuroprotective Target in Glaucoma
Q52584082The SERCA2: A Gatekeeper of Neuronal Calcium Homeostasis in the Brain.
Q47681865The STIM-Orai Pathway: Light-Operated Ca2+ Entry Through Engineered CRAC Channels.
Q33929772The TRPC channel blocker SKF 96365 inhibits glioblastoma cell growth by enhancing reverse mode of the Na(+) /Ca(2+) exchanger and increasing intracellular Ca(2+).
Q54489074The ability of phosphodiesterase-5 inhibitors sildenafil and ordonafil to reverse L-NAME induced cardiac hypertrophy in the rabbit: possible role of calcineurin and p38.
Q73109599The alpha7 nicotinic acetylcholine receptor subtype mediates nicotine protection against NMDA excitotoxicity in primary hippocampal cultures through a Ca(2+) dependent mechanism
Q57697436The association between Darier disease, bipolar disorder, and schizophrenia revisited: a population-based family study
Q35825859The cell biology of lysosomal storage disorders
Q34988284The cellular and molecular basis of store-operated calcium entry
Q38437151The central role of aquaporins in the pathophysiology of ischemic stroke.
Q28193254The cyclo-oxygenase-2 inhibitor celecoxib perturbs intracellular calcium by inhibiting endoplasmic reticulum Ca2+-ATPases: a plausible link with its anti-tumour effect and cardiovascular risks
Q40450435The cytoplasmic C-terminus of polycystin-1 increases cell proliferation in kidney epithelial cells through serum-activated and Ca(2+)-dependent pathway(s).
Q40655185The effect of oxygen tension on calcium homeostasis in bovine articular chondrocytes
Q38724143The effects of electromagnetic fields on B16-BL6 cells are dependent on their spatial and temporal character.
Q38967010The emerging neuroprotective role of mitochondrial uncoupling protein-2 in traumatic brain injury
Q35051249The endoplasmic reticulum: a multifunctional signaling organelle
Q39451898The hepatitis B virus X protein elevates cytosolic calcium signals by modulating mitochondrial calcium uptake
Q44087961The influence of different InsP(3) receptor isoforms on Ca(2+) signaling in tracheal smooth muscle cells
Q40826472The invasion protein InIB from Listeria monocytogenes activates PLC-gamma1 downstream from PI 3-kinase
Q35040631The involvement of PI3K-mediated and L-VGCC-gated transient Ca2+ influx in 17β-estradiol-mediated protection of retinal cells from H2O2-induced apoptosis with Ca2+ overload.
Q44137992The mechanism of inhibition of the sarco/endoplasmic reticulum Ca2+ ATPase by paxilline
Q38569106The molecular era of the mitochondrial calcium uniporter
Q92386466The neuroprotective mechanism of cinnamaldehyde against amyloid-β in neuronal SHSY5Y cell line: The role of N-methyl-D-aspartate, ryanodine, and adenosine receptors and glycogen synthase kinase-3β
Q44174069The novel endoplasmic reticulum (ER)-targeted protein HAP induces cell apoptosis by the depletion of the ER Ca(2+) stores
Q33257839The number and spatial distribution of IP3 receptors underlying calcium puffs in Xenopus oocytes
Q38066188The other side of cardiac Ca(2+) signaling: transcriptional control
Q36954095The pathogenesis of Alzheimers disease is it a lifelong "calciumopathy"?
Q61889536The plasma membrane calcium pump
Q46408097The pleiotropic vegetative and sexual development phenotypes of Neurospora crassa arise from double mutants of the calcium signaling genes plc-1, splA2, and cpe-1.
Q28142122The postmitotic growth suppressor necdin interacts with a calcium-binding protein (NEFA) in neuronal cytoplasm
Q33861172The protection of hepatocyte cells from the effects of oxidative stress by treatment with vitamin E in conjunction with DTT
Q34599899The receptor-like properties of nitric oxide-activated soluble guanylyl cyclase in intact cells.
Q33731222The recombinant 5-HT1A receptor: G protein coupling and signalling pathways.
Q93173303The roles of mechanosensitive ion channels and associated downstream MAPK signaling pathways in PDLC mechanotransduction
Q35755257The ryanodine receptor is essential for larval development in Drosophila melanogaster
Q35010395The uremic toxin indoxyl sulphate enhances macrophage response to LPS.
Q35393443The vitamin D, ionised calcium and parathyroid hormone axis of cerebral capillary function: therapeutic considerations for vascular-based neurodegenerative disorders
Q46428272The voltage-dependent anion channel-1 modulates apoptotic cell death.
Q43075990The widely utilized brominated flame retardant tetrabromobisphenol A (TBBPA) is a potent inhibitor of the SERCA Ca2+ pump
Q39864024Thiazolidinediones induce proliferation of human bronchial epithelial cells through the GPR40 receptor.
Q48019893Toxicity of industrially relevant chlorinated organic solvents in vitro
Q74643574Transcriptional activation of the human S100A2 promoter by wild-type p53
Q36363852Transcriptome analysis identifies genes involved in adventitious branches formation of Gracilaria lichenoides in vitro
Q40995826Transcriptomic and metabolomic profiles of Chinese citrus fly, Bactrocera minax (Diptera: Tephritidae), along with pupal development provide insight into diapause program.
Q53691564Transcriptomic study to understand thermal adaptation in a high temperature-tolerant strain of Pyropia haitanensis.
Q28364864Transfection of annexin 1 in monocytic cells produces a high degree of spontaneous and stimulated apoptosis associated with caspase-3 activation
Q30437245Transfer of beta subunit regulation from high to low voltage-gated Ca2+ channels
Q39646750Transformation of local Ca2+ spikes to global Ca2+ transients: the combinatorial roles of multiple Ca2+ releasing messengers
Q36372840Transient and sustained increases in inositol 1,4,5-trisphosphate precede the differential growth response in gravistimulated maize pulvini
Q28613792Transient receptor potential 1 regulates capacitative Ca(2+) entry and Ca(2+) release from endoplasmic reticulum in B lymphocytes
Q36681384Transient receptor potential melastatin 7-like current in human head and neck carcinoma cells: role in cell proliferation
Q42069897Transition from stochastic to deterministic behavior in calcium oscillations.
Q28575512Translational mobility of the type 3 inositol 1,4,5-trisphosphate receptor Ca2+ release channel in endoplasmic reticulum membrane
Q46907491Transmembrane redox sensor of ryanodine receptor complex
Q40213839Transthyretin oligomers induce calcium influx via voltage-gated calcium channels.
Q48591636Treatment with Ca2+ ionophore improves embryo development and outcome in cases with previous developmental problems: a prospective multicenter study
Q39369740Type 1 inositol-1,4,5-trisphosphate receptor is a late substrate of caspases during apoptosis
Q34864568Type-specific inositol 1,4,5-trisphosphate receptor localization in the vomeronasal organ and its interaction with a transient receptor potential channel, TRPC2
Q28577738UTP affects the Schwannoma cell line proteome through P2Y receptors leading to cytoskeletal reorganisation
Q47312886Ultrafast Near-Infrared Light-triggered Intracellular Uncaging to Probe Cell Signaling
Q43274235Ultrasound and microbubble-induced intra- and intercellular bioeffects in primary endothelial cells
Q30491066Ultrasound and microbubble-targeted delivery of therapeutic compounds: ICIN Report Project 49: Drug and gene delivery through ultrasound and microbubbles.
Q52009638Under what conditions signal transduction pathways are highly flexible in response to external forcing? A case study on calcium oscillations.
Q38412791Understanding anomalous delays in a model of intracellular calcium dynamics
Q36650244Unique Regulatory Properties of Heterotetrameric Inositol 1,4,5-Trisphosphate Receptors Revealed by Studying Concatenated Receptor Constructs
Q42254591Unique kinetics of nicotinic acid-adenine dinucleotide phosphate (NAADP) binding enhance the sensitivity of NAADP receptors for their ligand
Q43698993Unreliability of the cytochrome c-enhanced green fluorescent fusion protein as a marker of cytochrome c release in cells that overexpress Bcl-2.
Q35874513Up-regulation of Orai1 expression and store operated Ca(2+) entry following activation of membrane androgen receptors in MCF-7 breast tumor cells
Q51037112Vanilloid receptor 1 regulates multiple calcium compartments and contributes to Ca2+-induced Ca2+ release in sensory neurons.
Q24597190Viral calciomics: interplays between Ca2+ and virus
Q38164707Viruses as modulators of mitochondrial functions
Q38086727Vitamin D and heart
Q49966377Wave failure at strong coupling in intracellular Ca^{2+} signaling system with clustered channels
Q85913942Window current through the T-type Ca2+ channel triggers the mechanism for cellular apoptosis via mitochondrial pathways
Q36323273Wnt-5/pipetail functions in vertebrate axis formation as a negative regulator of Wnt/beta-catenin activity.
Q27670768X-ray structures of magnesium and manganese complexes with the N-terminal domain of calmodulin: insights into the mechanism and specificity of metal ion binding to an EF-hand.
Q43263790Xestospongin C, a novel blocker of IP3 receptor, attenuates the increase in cytosolic calcium level and degranulation that is induced by antigen in RBL-2H3 mast cells
Q35795820Yeast mitochondrial interactosome model: metabolon membrane proteins complex involved in the channeling of ADP/ATP
Q81614117[Evolution of mechanisms of Calcium signaling: the role of Calcium ions in signal transduction in prokaryotes]
Q42158584cADP-ribose potentiates cytosolic Ca2+ elevation and Ca2+ entry via L-type voltage-activated Ca2+ channels in NG108-15 neuronal cells

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