Patients with early rheumatoid arthritis who smoke are less likely to respond to treatment with methotrexate and tumor necrosis factor inhibitors: Observations from the Epidemiological Investigation of Rheumatoid Arthritis and the Swedish Rheumatolog

scholarly article by Saedis Saevarsdottir et al published 28 December 2010 in Arthritis and Rheumatism

Patients with early rheumatoid arthritis who smoke are less likely to respond to treatment with methotrexate and tumor necrosis factor inhibitors: Observations from the Epidemiological Investigation of Rheumatoid Arthritis and the Swedish Rheumatolog is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/ART.27758
P698PubMed publication ID20862678

P50authorLars KlareskogQ5912759
Johan AsklingQ89669829
Saedis SaevarsdottirQ90603200
Sara WedrénQ114337587
Staffan LindbladQ114341727
Maria SeddighzadehQ114341730
Annmarie WesleyQ114402425
Lars AlfredssonQ30349390
P2093author name stringCamilla Bengtsson
P2860cites workRheumatoid arthritis patients who smoke have a higher need for DMARDs and feel worse, but they do not have more joint damage than non-smokers of the same serological group.Q52919247
Rheumatoid arthritisQ57349151
Predictors of response to anti-TNF- therapy among patients with rheumatoid arthritis: results from the British Society for Rheumatology Biologics RegisterQ57751361
A clinical pharmacogenetic model to predict the efficacy of methotrexate monotherapy in recent-onset rheumatoid arthritisQ57788757
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Extra-articular disease manifestations in rheumatoid arthritis: incidence trends and risk factors over 46 yearsQ24674079
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A gene-environment interaction between smoking and shared epitope genes in HLA-DR provides a high risk of seropositive rheumatoid arthritisQ33982255
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Cigarette smoking and rheumatoid arthritis severityQ35547371
HLA-DRB1 typing in rheumatoid arthritis: predicting response to specific treatmentsQ35547815
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Can clinical factors at presentation be used to predict outcome of treatment with methotrexate in patients with early inflammatory polyarthritis?Q37000103
Association of rheumatoid factor and anti-cyclic citrullinated peptide positivity, but not carriage of shared epitope or PTPN22 susceptibility variants, with anti-tumour necrosis factor response in rheumatoid arthritisQ37000109
The BeSt story: on strategy trials in rheumatoid arthritisQ37422987
Recent progress in rheumatoid arthritis genetics: one step towards improved patient careQ37443734
Progression of joint damage in early rheumatoid arthritis: association with HLA-DRB1, rheumatoid factor, and anti-citrullinated protein antibodies in relation to different treatment strategiesQ42653404
A new model for an etiology of rheumatoid arthritis: smoking may trigger HLA-DR (shared epitope)-restricted immune reactions to autoantigens modified by citrullinationQ42676934
Anti-TNF-alpha agents are less effective for the treatment of rheumatoid arthritis in current smokersQ43201741
Determinants of red blood cell methotrexate polyglutamate concentrations in rheumatoid arthritis patients receiving long-term methotrexate treatmentQ45915302
The influence of genetic variation in the HLA-DRB1 and LTA-TNF regions on the response to treatment of early rheumatoid arthritis with methotrexate or etanerceptQ46114766
Relationship between pack-year history of smoking and response to tumor necrosis factor antagonists in patients with rheumatoid arthritisQ47784100
High disease activity disability burden and smoking predict severe extra-articular manifestations in early rheumatoid arthritis.Q51824341
P433issue1
P921main subjectimmunologyQ101929
patientQ181600
epidemiologyQ133805
rheumatoid arthritisQ187255
rheumatologyQ327657
methotrexateQ422232
P304page(s)26-36
P577publication date2010-12-28
P1433published inArthritis and RheumatismQ23929027
P1476titlePatients with early rheumatoid arthritis who smoke are less likely to respond to treatment with methotrexate and tumor necrosis factor inhibitors: Observations from the Epidemiological Investigation of Rheumatoid Arthritis and the Swedish Rheumatolog
P478volume63

Reverse relations

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